FI111713B - Menetelmä selegiliinin valmistamiseksi - Google Patents

Menetelmä selegiliinin valmistamiseksi Download PDF

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Publication number
FI111713B
FI111713B FI971038A FI971038A FI111713B FI 111713 B FI111713 B FI 111713B FI 971038 A FI971038 A FI 971038A FI 971038 A FI971038 A FI 971038A FI 111713 B FI111713 B FI 111713B
Authority
FI
Finland
Prior art keywords
selegiline
hydrochloride
bromo
reaction
pct
Prior art date
Application number
FI971038A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI971038A (fi
FI971038A0 (fi
Inventor
Silvia Ott-Dembrowski
Richard Cyrus
Joerg Schmidt
Hans Waiblinger
Original Assignee
Knoll Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Knoll Ag filed Critical Knoll Ag
Publication of FI971038A publication Critical patent/FI971038A/fi
Publication of FI971038A0 publication Critical patent/FI971038A0/fi
Application granted granted Critical
Publication of FI111713B publication Critical patent/FI111713B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C209/00Preparation of compounds containing amino groups bound to a carbon skeleton
    • C07C209/60Preparation of compounds containing amino groups bound to a carbon skeleton by condensation or addition reactions, e.g. Mannich reaction, addition of ammonia or amines to alkenes or to alkynes or addition of compounds containing an active hydrogen atom to Schiff's bases, quinone imines, or aziranes

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Saccharide Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
FI971038A 1994-09-13 1997-03-12 Menetelmä selegiliinin valmistamiseksi FI111713B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE4432610 1994-09-13
DE4432610A DE4432610C1 (de) 1994-09-13 1994-09-13 Verfahren zur Herstellung von Selegilin-Hydrochlorid
PCT/EP1995/003460 WO1996008461A1 (de) 1994-09-13 1995-09-02 Verfahren zur herstellung von selegilin
EP9503460 1995-09-02

Publications (3)

Publication Number Publication Date
FI971038A FI971038A (fi) 1997-03-12
FI971038A0 FI971038A0 (fi) 1997-03-12
FI111713B true FI111713B (fi) 2003-09-15

Family

ID=6528113

Family Applications (1)

Application Number Title Priority Date Filing Date
FI971038A FI111713B (fi) 1994-09-13 1997-03-12 Menetelmä selegiliinin valmistamiseksi

Country Status (15)

Country Link
US (1) US5847216A (cs)
EP (1) EP0772584B1 (cs)
JP (1) JPH10505602A (cs)
AT (1) ATE167469T1 (cs)
AU (1) AU3520895A (cs)
CA (1) CA2198781C (cs)
CZ (1) CZ287647B6 (cs)
DE (2) DE4432610C1 (cs)
DK (1) DK0772584T3 (cs)
ES (1) ES2117445T3 (cs)
FI (1) FI111713B (cs)
HU (1) HU214840B (cs)
IL (1) IL115157A (cs)
MX (1) MX9701831A (cs)
WO (1) WO1996008461A1 (cs)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19716905C1 (de) * 1997-04-22 1998-08-27 Iip Inst Fuer Ind Pharmazie Fo Stabile, wäßrige Lösung auf der Grundlage von Selegilin und Vorrichtung zu ihrer Verabreichung
US10189803B2 (en) 2008-02-22 2019-01-29 Illinois Institute Of Technology Synthesis of therapeutic and diagnostic drugs centered on regioselective and stereoselective ring opening of aziridinium ions
US9446995B2 (en) 2012-05-21 2016-09-20 Illinois Institute Of Technology Synthesis of therapeutic and diagnostic drugs centered on regioselective and stereoselective ring opening of aziridinium ions
WO2015051362A1 (en) 2013-10-04 2015-04-09 Illinois Institute Of Technology Multifunctional chelators, complexes, and compositions thereof, and methods of using same

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH393306A (de) * 1962-03-30 1965-06-15 Wander Ag Dr A Verfahren zur Herstellung von tertiären Aminen der Phenylalkylreihe
GB1121857A (en) * 1965-01-05 1968-07-31 Science Union & Cie New phenylisopropylamine derivatives and process for their preparation and pharmaceutical preparations of such derivatives
US3485874A (en) * 1966-05-04 1969-12-23 Chinoin Gyogyszer Es Vegyeszet Ortho and para bromophenyl isopropyl methylamines
US4156017A (en) * 1977-02-22 1979-05-22 Schering Aktiengesellschaft Pesticides
HU187775B (en) * 1982-07-14 1986-02-28 Chinoin Gyogyszer Es Vegyeszeti Termekek Gyara Rt,Hu New process for producing propargile-amines of pharmaceutical activity
CS269271B1 (en) * 1988-05-30 1990-04-11 Hajicek Josef Method of selegiline's hydrochloride production
HUT63579A (en) * 1991-12-20 1993-09-28 Chinoin Gyogyszer Es Vegyeszet Process for producing double-phase pharmaceutical compositions suitable for treating diseases occurring during neurodegenerative processes

Also Published As

Publication number Publication date
CA2198781A1 (en) 1996-03-21
CZ77597A3 (cs) 1998-02-18
DK0772584T3 (da) 1998-10-19
CA2198781C (en) 2004-08-24
FI971038A (fi) 1997-03-12
WO1996008461A1 (de) 1996-03-21
ATE167469T1 (de) 1998-07-15
HUT77185A (hu) 1998-03-02
CZ287647B6 (en) 2001-01-17
AU3520895A (en) 1996-03-29
DE4432610C1 (de) 1996-02-01
HU214840B (hu) 1998-06-29
IL115157A (en) 1999-05-09
FI971038A0 (fi) 1997-03-12
EP0772584B1 (de) 1998-06-17
ES2117445T3 (es) 1998-08-01
EP0772584A1 (de) 1997-05-14
US5847216A (en) 1998-12-08
MX9701831A (es) 1997-06-28
JPH10505602A (ja) 1998-06-02
DE59502606D1 (de) 1998-07-23
IL115157A0 (en) 1995-12-31

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