FI111383B - Menetelmä runsaasti hivenaineita sisältävän lisäaineen valmistamiseksi - Google Patents
Menetelmä runsaasti hivenaineita sisältävän lisäaineen valmistamiseksi Download PDFInfo
- Publication number
- FI111383B FI111383B FI935408A FI935408A FI111383B FI 111383 B FI111383 B FI 111383B FI 935408 A FI935408 A FI 935408A FI 935408 A FI935408 A FI 935408A FI 111383 B FI111383 B FI 111383B
- Authority
- FI
- Finland
- Prior art keywords
- selenium
- additive
- trace
- culture medium
- bacteria
- Prior art date
Links
- 238000000034 method Methods 0.000 title claims abstract description 15
- 230000008569 process Effects 0.000 title claims description 7
- 239000000654 additive Substances 0.000 title abstract description 26
- 230000000996 additive effect Effects 0.000 title abstract description 26
- 239000011573 trace mineral Substances 0.000 title abstract description 15
- 235000013619 trace mineral Nutrition 0.000 title abstract description 15
- 238000002360 preparation method Methods 0.000 title abstract description 12
- 239000011669 selenium Substances 0.000 claims abstract description 43
- BUGBHKTXTAQXES-UHFFFAOYSA-N Selenium Chemical compound [Se] BUGBHKTXTAQXES-UHFFFAOYSA-N 0.000 claims abstract description 30
- 229910052711 selenium Inorganic materials 0.000 claims abstract description 28
- 239000001963 growth medium Substances 0.000 claims abstract description 9
- 150000001875 compounds Chemical class 0.000 claims abstract description 3
- 241000894006 Bacteria Species 0.000 claims description 14
- 241000186660 Lactobacillus Species 0.000 claims description 6
- XEEYBQQBJWHFJM-UHFFFAOYSA-N Iron Chemical compound [Fe] XEEYBQQBJWHFJM-UHFFFAOYSA-N 0.000 claims description 4
- PXHVJJICTQNCMI-UHFFFAOYSA-N Nickel Chemical compound [Ni] PXHVJJICTQNCMI-UHFFFAOYSA-N 0.000 claims description 4
- 229940039696 lactobacillus Drugs 0.000 claims description 4
- 230000001580 bacterial effect Effects 0.000 claims description 3
- VYZAMTAEIAYCRO-UHFFFAOYSA-N Chromium Chemical compound [Cr] VYZAMTAEIAYCRO-UHFFFAOYSA-N 0.000 claims description 2
- RYGMFSIKBFXOCR-UHFFFAOYSA-N Copper Chemical compound [Cu] RYGMFSIKBFXOCR-UHFFFAOYSA-N 0.000 claims description 2
- HCHKCACWOHOZIP-UHFFFAOYSA-N Zinc Chemical compound [Zn] HCHKCACWOHOZIP-UHFFFAOYSA-N 0.000 claims description 2
- 229910052804 chromium Inorganic materials 0.000 claims description 2
- 239000011651 chromium Substances 0.000 claims description 2
- 239000010941 cobalt Substances 0.000 claims description 2
- 229910017052 cobalt Inorganic materials 0.000 claims description 2
- GUTLYIVDDKVIGB-UHFFFAOYSA-N cobalt atom Chemical compound [Co] GUTLYIVDDKVIGB-UHFFFAOYSA-N 0.000 claims description 2
- 229910052802 copper Inorganic materials 0.000 claims description 2
- 239000010949 copper Substances 0.000 claims description 2
- 229910052742 iron Inorganic materials 0.000 claims description 2
- WPBNNNQJVZRUHP-UHFFFAOYSA-L manganese(2+);methyl n-[[2-(methoxycarbonylcarbamothioylamino)phenyl]carbamothioyl]carbamate;n-[2-(sulfidocarbothioylamino)ethyl]carbamodithioate Chemical compound [Mn+2].[S-]C(=S)NCCNC([S-])=S.COC(=O)NC(=S)NC1=CC=CC=C1NC(=S)NC(=O)OC WPBNNNQJVZRUHP-UHFFFAOYSA-L 0.000 claims description 2
- 238000004519 manufacturing process Methods 0.000 claims description 2
- 229910052759 nickel Inorganic materials 0.000 claims description 2
- 239000011701 zinc Substances 0.000 claims description 2
- 229910052725 zinc Inorganic materials 0.000 claims description 2
- 239000002981 blocking agent Substances 0.000 claims 2
- 239000000575 pesticide Substances 0.000 claims 2
- 241000186672 Lactobacillus delbrueckii subsp. bulgaricus Species 0.000 claims 1
- 235000020939 nutritional additive Nutrition 0.000 claims 1
- 125000003748 selenium group Chemical group *[Se]* 0.000 claims 1
- 244000005700 microbiome Species 0.000 abstract description 12
- 235000013305 food Nutrition 0.000 abstract description 8
- 238000012258 culturing Methods 0.000 abstract description 4
- 230000001225 therapeutic effect Effects 0.000 abstract description 3
- 206010044278 Trace element deficiency Diseases 0.000 abstract description 2
- 238000009825 accumulation Methods 0.000 abstract 1
- 235000018102 proteins Nutrition 0.000 description 14
- 102000004169 proteins and genes Human genes 0.000 description 14
- 108090000623 proteins and genes Proteins 0.000 description 14
- 229940082569 selenite Drugs 0.000 description 13
- MCAHWIHFGHIESP-UHFFFAOYSA-L selenite(2-) Chemical compound [O-][Se]([O-])=O MCAHWIHFGHIESP-UHFFFAOYSA-L 0.000 description 13
- RJFAYQIBOAGBLC-BYPYZUCNSA-N Selenium-L-methionine Chemical compound C[Se]CC[C@H](N)C(O)=O RJFAYQIBOAGBLC-BYPYZUCNSA-N 0.000 description 12
- RJFAYQIBOAGBLC-UHFFFAOYSA-N Selenomethionine Natural products C[Se]CCC(N)C(O)=O RJFAYQIBOAGBLC-UHFFFAOYSA-N 0.000 description 12
- 230000000694 effects Effects 0.000 description 12
- 229960002718 selenomethionine Drugs 0.000 description 12
- 244000199885 Lactobacillus bulgaricus Species 0.000 description 8
- 239000013589 supplement Substances 0.000 description 8
- 102000006587 Glutathione peroxidase Human genes 0.000 description 7
- 229940065287 selenium compound Drugs 0.000 description 7
- 150000003343 selenium compounds Chemical class 0.000 description 7
- ZKZBPNGNEQAJSX-UHFFFAOYSA-N selenocysteine Natural products [SeH]CC(N)C(O)=O ZKZBPNGNEQAJSX-UHFFFAOYSA-N 0.000 description 7
- FDKWRPBBCBCIGA-REOHCLBHSA-N (2r)-2-azaniumyl-3-$l^{1}-selanylpropanoate Chemical compound [Se]C[C@H](N)C(O)=O FDKWRPBBCBCIGA-REOHCLBHSA-N 0.000 description 6
- FDKWRPBBCBCIGA-UWTATZPHSA-N D-Selenocysteine Natural products [Se]C[C@@H](N)C(O)=O FDKWRPBBCBCIGA-UWTATZPHSA-N 0.000 description 6
- 108700016172 Glutathione peroxidases Proteins 0.000 description 6
- 235000005911 diet Nutrition 0.000 description 6
- 230000037213 diet Effects 0.000 description 6
- 229940055619 selenocysteine Drugs 0.000 description 6
- 235000016491 selenocysteine Nutrition 0.000 description 6
- 230000007812 deficiency Effects 0.000 description 5
- RWSXRVCMGQZWBV-WDSKDSINSA-N glutathione Chemical compound OC(=O)[C@@H](N)CCC(=O)N[C@@H](CS)C(=O)NCC(O)=O RWSXRVCMGQZWBV-WDSKDSINSA-N 0.000 description 5
- 239000002609 medium Substances 0.000 description 5
- 230000002950 deficient Effects 0.000 description 4
- 201000010099 disease Diseases 0.000 description 4
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 description 4
- 108010024636 Glutathione Proteins 0.000 description 3
- 241000699670 Mus sp. Species 0.000 description 3
- 240000004808 Saccharomyces cerevisiae Species 0.000 description 3
- 230000000259 anti-tumor effect Effects 0.000 description 3
- 210000004027 cell Anatomy 0.000 description 3
- 210000000936 intestine Anatomy 0.000 description 3
- 208000024891 symptom Diseases 0.000 description 3
- 241000282414 Homo sapiens Species 0.000 description 2
- 208000019926 Keshan disease Diseases 0.000 description 2
- 235000013960 Lactobacillus bulgaricus Nutrition 0.000 description 2
- 241001465754 Metazoa Species 0.000 description 2
- 208000029578 Muscle disease Diseases 0.000 description 2
- 102000008114 Selenoproteins Human genes 0.000 description 2
- 108010074686 Selenoproteins Proteins 0.000 description 2
- 239000005862 Whey Substances 0.000 description 2
- 102000007544 Whey Proteins Human genes 0.000 description 2
- 108010046377 Whey Proteins Proteins 0.000 description 2
- 238000010521 absorption reaction Methods 0.000 description 2
- 235000001014 amino acid Nutrition 0.000 description 2
- 150000001413 amino acids Chemical class 0.000 description 2
- 230000008901 benefit Effects 0.000 description 2
- 210000002421 cell wall Anatomy 0.000 description 2
- 238000002474 experimental method Methods 0.000 description 2
- 229960003180 glutathione Drugs 0.000 description 2
- 150000004676 glycans Chemical class 0.000 description 2
- 229910001385 heavy metal Inorganic materials 0.000 description 2
- 150000002484 inorganic compounds Chemical class 0.000 description 2
- 229910010272 inorganic material Inorganic materials 0.000 description 2
- 230000000968 intestinal effect Effects 0.000 description 2
- 229940004208 lactobacillus bulgaricus Drugs 0.000 description 2
- QSHDDOUJBYECFT-UHFFFAOYSA-N mercury Chemical compound [Hg] QSHDDOUJBYECFT-UHFFFAOYSA-N 0.000 description 2
- 229910052753 mercury Inorganic materials 0.000 description 2
- 208000030159 metabolic disease Diseases 0.000 description 2
- 235000016709 nutrition Nutrition 0.000 description 2
- 230000035764 nutrition Effects 0.000 description 2
- 150000002894 organic compounds Chemical class 0.000 description 2
- 230000036542 oxidative stress Effects 0.000 description 2
- 229920001282 polysaccharide Polymers 0.000 description 2
- 239000005017 polysaccharide Substances 0.000 description 2
- JULROCUWKLNBSN-UHFFFAOYSA-N selenocystine Chemical compound OC(=O)C(N)C[Se][Se]CC(N)C(O)=O JULROCUWKLNBSN-UHFFFAOYSA-N 0.000 description 2
- 230000004584 weight gain Effects 0.000 description 2
- 235000019786 weight gain Nutrition 0.000 description 2
- 210000005253 yeast cell Anatomy 0.000 description 2
- 208000019838 Blood disease Diseases 0.000 description 1
- 208000024172 Cardiovascular disease Diseases 0.000 description 1
- 108020004705 Codon Proteins 0.000 description 1
- 102000004420 Creatine Kinase Human genes 0.000 description 1
- 108010042126 Creatine kinase Proteins 0.000 description 1
- 102000004190 Enzymes Human genes 0.000 description 1
- 108090000790 Enzymes Proteins 0.000 description 1
- 102100033053 Glutathione peroxidase 3 Human genes 0.000 description 1
- 101710119049 Glutathione peroxidase 3 Proteins 0.000 description 1
- 206010019030 Hair colour changes Diseases 0.000 description 1
- 241000282412 Homo Species 0.000 description 1
- 206010020751 Hypersensitivity Diseases 0.000 description 1
- FFEARJCKVFRZRR-BYPYZUCNSA-N L-methionine Chemical compound CSCC[C@H](N)C(O)=O FFEARJCKVFRZRR-BYPYZUCNSA-N 0.000 description 1
- 244000199866 Lactobacillus casei Species 0.000 description 1
- 240000006024 Lactobacillus plantarum Species 0.000 description 1
- KDXKERNSBIXSRK-UHFFFAOYSA-N Lysine Natural products NCCCCC(N)C(O)=O KDXKERNSBIXSRK-UHFFFAOYSA-N 0.000 description 1
- 239000004472 Lysine Substances 0.000 description 1
- 208000010428 Muscle Weakness Diseases 0.000 description 1
- 206010028372 Muscular weakness Diseases 0.000 description 1
- 206010028980 Neoplasm Diseases 0.000 description 1
- 208000005374 Poisoning Diseases 0.000 description 1
- 206010039921 Selenium deficiency Diseases 0.000 description 1
- 208000024799 Thyroid disease Diseases 0.000 description 1
- 208000024780 Urticaria Diseases 0.000 description 1
- 230000002378 acidificating effect Effects 0.000 description 1
- 230000032683 aging Effects 0.000 description 1
- 208000030961 allergic reaction Diseases 0.000 description 1
- 230000008485 antagonism Effects 0.000 description 1
- 206010003119 arrhythmia Diseases 0.000 description 1
- 206010003246 arthritis Diseases 0.000 description 1
- 208000006673 asthma Diseases 0.000 description 1
- 239000008280 blood Substances 0.000 description 1
- 210000004369 blood Anatomy 0.000 description 1
- 210000004958 brain cell Anatomy 0.000 description 1
- 239000006227 byproduct Substances 0.000 description 1
- 229910052793 cadmium Inorganic materials 0.000 description 1
- BDOSMKKIYDKNTQ-UHFFFAOYSA-N cadmium atom Chemical compound [Cd] BDOSMKKIYDKNTQ-UHFFFAOYSA-N 0.000 description 1
- 201000011510 cancer Diseases 0.000 description 1
- 239000000969 carrier Substances 0.000 description 1
- 230000001413 cellular effect Effects 0.000 description 1
- 238000005119 centrifugation Methods 0.000 description 1
- 235000013351 cheese Nutrition 0.000 description 1
- 230000001684 chronic effect Effects 0.000 description 1
- 235000013365 dairy product Nutrition 0.000 description 1
- 230000001627 detrimental effect Effects 0.000 description 1
- 239000003085 diluting agent Substances 0.000 description 1
- 230000008030 elimination Effects 0.000 description 1
- 238000003379 elimination reaction Methods 0.000 description 1
- 238000001914 filtration Methods 0.000 description 1
- 230000002496 gastric effect Effects 0.000 description 1
- 210000001035 gastrointestinal tract Anatomy 0.000 description 1
- 208000014951 hematologic disease Diseases 0.000 description 1
- 208000018706 hematopoietic system disease Diseases 0.000 description 1
- 230000008799 immune stress Effects 0.000 description 1
- 238000001727 in vivo Methods 0.000 description 1
- 230000035987 intoxication Effects 0.000 description 1
- 231100000566 intoxication Toxicity 0.000 description 1
- 230000000366 juvenile effect Effects 0.000 description 1
- 230000007774 longterm Effects 0.000 description 1
- 239000003264 margarine Substances 0.000 description 1
- 235000013310 margarine Nutrition 0.000 description 1
- 230000007246 mechanism Effects 0.000 description 1
- 108020004999 messenger RNA Proteins 0.000 description 1
- 229930182817 methionine Natural products 0.000 description 1
- 235000013336 milk Nutrition 0.000 description 1
- 239000008267 milk Substances 0.000 description 1
- 210000004080 milk Anatomy 0.000 description 1
- 230000002297 mitogenic effect Effects 0.000 description 1
- 210000004165 myocardium Anatomy 0.000 description 1
- 230000004770 neurodegeneration Effects 0.000 description 1
- 208000015122 neurodegenerative disease Diseases 0.000 description 1
- 230000000926 neurological effect Effects 0.000 description 1
- 231100000252 nontoxic Toxicity 0.000 description 1
- 230000003000 nontoxic effect Effects 0.000 description 1
- 230000000474 nursing effect Effects 0.000 description 1
- 235000016236 parenteral nutrition Nutrition 0.000 description 1
- 244000052769 pathogen Species 0.000 description 1
- 230000037361 pathway Effects 0.000 description 1
- 231100000572 poisoning Toxicity 0.000 description 1
- 230000000607 poisoning effect Effects 0.000 description 1
- 230000008092 positive effect Effects 0.000 description 1
- 239000000047 product Substances 0.000 description 1
- 230000002035 prolonged effect Effects 0.000 description 1
- 238000005922 selenation reaction Methods 0.000 description 1
- 238000000926 separation method Methods 0.000 description 1
- 239000000126 substance Substances 0.000 description 1
- 230000009469 supplementation Effects 0.000 description 1
- 208000021510 thyroid gland disease Diseases 0.000 description 1
- 231100000331 toxic Toxicity 0.000 description 1
- 230000002588 toxic effect Effects 0.000 description 1
- 231100000419 toxicity Toxicity 0.000 description 1
- 230000001988 toxicity Effects 0.000 description 1
- 235000013343 vitamin Nutrition 0.000 description 1
- 239000011782 vitamin Substances 0.000 description 1
- 229940088594 vitamin Drugs 0.000 description 1
- 229930003231 vitamin Natural products 0.000 description 1
- 230000002087 whitening effect Effects 0.000 description 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
- A61K35/66—Microorganisms or materials therefrom
- A61K35/74—Bacteria
- A61K35/741—Probiotics
- A61K35/744—Lactic acid bacteria, e.g. enterococci, pediococci, lactococci, streptococci or leuconostocs
- A61K35/747—Lactobacilli, e.g. L. acidophilus or L. brevis
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L29/00—Foods or foodstuffs containing additives; Preparation or treatment thereof
- A23L29/065—Microorganisms
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23L—FOODS, FOODSTUFFS, OR NON-ALCOHOLIC BEVERAGES, NOT COVERED BY SUBCLASSES A21D OR A23B-A23J; THEIR PREPARATION OR TREATMENT, e.g. COOKING, MODIFICATION OF NUTRITIVE QUALITIES, PHYSICAL TREATMENT; PRESERVATION OF FOODS OR FOODSTUFFS, IN GENERAL
- A23L33/00—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof
- A23L33/10—Modifying nutritive qualities of foods; Dietetic products; Preparation or treatment thereof using additives
- A23L33/16—Inorganic salts, minerals or trace elements
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/20—Bacteria; Culture media therefor
- C12N1/205—Bacterial isolates
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N1/00—Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
- C12N1/38—Chemical stimulation of growth or activity by addition of chemical compounds which are not essential growth factors; Stimulation of growth by removal of a chemical compound
-
- A—HUMAN NECESSITIES
- A23—FOODS OR FOODSTUFFS; TREATMENT THEREOF, NOT COVERED BY OTHER CLASSES
- A23V—INDEXING SCHEME RELATING TO FOODS, FOODSTUFFS OR NON-ALCOHOLIC BEVERAGES AND LACTIC OR PROPIONIC ACID BACTERIA USED IN FOODSTUFFS OR FOOD PREPARATION
- A23V2400/00—Lactic or propionic acid bacteria
- A23V2400/11—Lactobacillus
- A23V2400/123—Bulgaricus
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12R—INDEXING SCHEME ASSOCIATED WITH SUBCLASSES C12C - C12Q, RELATING TO MICROORGANISMS
- C12R2001/00—Microorganisms ; Processes using microorganisms
- C12R2001/01—Bacteria or Actinomycetales ; using bacteria or Actinomycetales
- C12R2001/225—Lactobacillus
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Organic Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Microbiology (AREA)
- Biotechnology (AREA)
- Zoology (AREA)
- Wood Science & Technology (AREA)
- Genetics & Genomics (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Biochemistry (AREA)
- Biomedical Technology (AREA)
- General Engineering & Computer Science (AREA)
- Virology (AREA)
- Tropical Medicine & Parasitology (AREA)
- Mycology (AREA)
- Nutrition Science (AREA)
- Food Science & Technology (AREA)
- Polymers & Plastics (AREA)
- Pharmacology & Pharmacy (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Inorganic Chemistry (AREA)
- Epidemiology (AREA)
- Molecular Biology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Coloring Foods And Improving Nutritive Qualities (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| EP91201350 | 1991-06-03 | ||
| EP91201350 | 1991-06-03 | ||
| PCT/EP1992/001328 WO1992021749A1 (en) | 1991-06-03 | 1992-06-03 | Trace element-rich additive, method for preparing same, preparation in which the additive is included and use thereof |
| EP9201328 | 1992-06-03 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI935408A FI935408A (fi) | 1993-12-02 |
| FI935408A0 FI935408A0 (fi) | 1993-12-02 |
| FI111383B true FI111383B (fi) | 2003-07-15 |
Family
ID=8207688
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI935408A FI111383B (fi) | 1991-06-03 | 1993-12-02 | Menetelmä runsaasti hivenaineita sisältävän lisäaineen valmistamiseksi |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US6479050B1 (sk) |
| EP (1) | EP0587711B1 (sk) |
| JP (1) | JP3338446B2 (sk) |
| AT (1) | ATE188247T1 (sk) |
| AU (1) | AU657763B2 (sk) |
| CA (1) | CA2110256A1 (sk) |
| CZ (1) | CZ283936B6 (sk) |
| DE (1) | DE69230495T2 (sk) |
| DK (1) | DK0587711T3 (sk) |
| ES (1) | ES2139599T3 (sk) |
| FI (1) | FI111383B (sk) |
| GR (1) | GR3032842T3 (sk) |
| HU (1) | HU218045B (sk) |
| NO (1) | NO314549B1 (sk) |
| PL (1) | PL170970B1 (sk) |
| SK (1) | SK280475B6 (sk) |
| WO (1) | WO1992021749A1 (sk) |
Families Citing this family (18)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB9226182D0 (en) * | 1992-12-16 | 1993-02-10 | Biotechna Ltd | Binding of metals and metalloids by microorganisms |
| FR2827301B1 (fr) * | 2001-07-13 | 2004-10-01 | Blue Energy Laboratoire | Procedes de fixation/complementation de molecules biologiquement actives par des cyanobacteries et des micro-algues ou des fractions de cyanobacteries et de micro-algues |
| WO2004071519A1 (fr) * | 2003-01-14 | 2004-08-26 | Bruneau Francois | Micro-organismes photosynthetiques enrichis en molecules biologiquement actives, leurs procedes de preparation, et leurs utilisations |
| ES2312948T3 (es) | 2004-06-03 | 2009-03-01 | Bioman S.R.L. | Biomasa enriquecida con selenio, procedimiento para su preparacion y productos probioticos y nutraceuticos que contienen dicha biomasa.-. |
| JP4514534B2 (ja) * | 2004-07-09 | 2010-07-28 | キユーピー株式会社 | 飲食品 |
| JP4700497B2 (ja) * | 2005-01-14 | 2011-06-15 | オリエンタル酵母工業株式会社 | ミネラル含有乳酸菌体によるクロロフィル含有食品の緑色の退色を防止し又は退色した緑色を復元する方法、及びクロロフィル含有食品の緑色の退色防止剤又は退色した緑色の復元剤 |
| JP2006230404A (ja) * | 2005-01-31 | 2006-09-07 | Kirin Well Foods Co Ltd | ミネラル含有乳酸菌を含んでなる食品または医薬品 |
| CN101163414A (zh) * | 2005-01-31 | 2008-04-16 | 麒麟益力多新时代健康食品股份有限公司 | 包含含矿物质的乳酸菌的食品或药品 |
| SE529199C2 (sv) | 2005-07-05 | 2007-05-29 | Probi Ab | Förstärkt absorption |
| US20070077238A1 (en) * | 2005-10-04 | 2007-04-05 | Teo Alex Y | Production of organic and inorganic selenium compounds by lactic acid bacteria |
| ITTO20070555A1 (it) * | 2007-07-26 | 2009-01-27 | Bioman S R L | Biomassa arricchita in zinco, procedimento per la sua preparazione e prodotti probiotici, cosmetici, dietetici e nutraceutici comprendenti tale biomassa |
| CZ303782B6 (cs) | 2008-11-18 | 2013-05-02 | Univerzita Palackého | Zarízení pro ozarování vzorku ultrazvukem |
| EP2556835B1 (en) | 2010-02-10 | 2015-08-05 | Japan Eco-Science Co. Ltd. | Mixture, dissolving solution and pharmaceutical agent each comprising thermophilic microorganism |
| CN103283974A (zh) * | 2013-03-27 | 2013-09-11 | 广州格拉姆生物科技有限公司 | 一种保加利亚乳杆菌活菌制剂的生产方法 |
| CN111088185A (zh) * | 2019-12-30 | 2020-05-01 | 光明乳业股份有限公司 | 一种富硒乳酸菌制剂及其制备方法 |
| CN110951652A (zh) * | 2019-12-30 | 2020-04-03 | 光明乳业股份有限公司 | 一种富硒乳酸菌制剂及其制备方法 |
| CN110982758A (zh) * | 2019-12-30 | 2020-04-10 | 光明乳业股份有限公司 | 一种富硒乳酸菌制剂及其制备方法 |
| CN110951651A (zh) * | 2019-12-30 | 2020-04-03 | 光明乳业股份有限公司 | 一种富硒乳酸菌制剂及其制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3024076A1 (de) | 1980-02-11 | 1981-08-20 | Anders Marius Holte Vognsen | Verfahren zur herstellung eines mineralstoffhaltigen praeparats |
| JPS61109729A (ja) * | 1984-11-05 | 1986-05-28 | Advance Res & Dev Co Ltd | コレステロ−ル低下剤 |
| US5185165A (en) * | 1989-01-23 | 1993-02-09 | Superior Fermitech Liquidating Trust | Fermentation system |
| CN1023409C (zh) | 1989-07-11 | 1994-01-05 | 杨振华 | 一种营养液的生产方法 |
| JPH0675279A (ja) * | 1992-08-28 | 1994-03-18 | Canon Inc | カメラのフィルム給送装置 |
| JPH06291177A (ja) * | 1993-03-31 | 1994-10-18 | Sony Corp | 半導体材料収納用具 |
-
1992
- 1992-06-03 HU HU9303417A patent/HU218045B/hu not_active IP Right Cessation
- 1992-06-03 SK SK1348-93A patent/SK280475B6/sk unknown
- 1992-06-03 CZ CS932557A patent/CZ283936B6/cs not_active IP Right Cessation
- 1992-06-03 CA CA002110256A patent/CA2110256A1/en not_active Abandoned
- 1992-06-03 AU AU19293/92A patent/AU657763B2/en not_active Ceased
- 1992-06-03 ES ES92912272T patent/ES2139599T3/es not_active Expired - Lifetime
- 1992-06-03 US US08/157,037 patent/US6479050B1/en not_active Expired - Fee Related
- 1992-06-03 JP JP51125092A patent/JP3338446B2/ja not_active Expired - Fee Related
- 1992-06-03 DE DE69230495T patent/DE69230495T2/de not_active Expired - Fee Related
- 1992-06-03 DK DK92912272T patent/DK0587711T3/da active
- 1992-06-03 AT AT92912272T patent/ATE188247T1/de not_active IP Right Cessation
- 1992-06-03 PL PL92297843A patent/PL170970B1/pl unknown
- 1992-06-03 EP EP92912272A patent/EP0587711B1/en not_active Expired - Lifetime
- 1992-06-03 WO PCT/EP1992/001328 patent/WO1992021749A1/en active IP Right Grant
-
1993
- 1993-12-02 FI FI935408A patent/FI111383B/fi active
- 1993-12-02 NO NO19934379A patent/NO314549B1/no not_active IP Right Cessation
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2000
- 2000-03-03 GR GR20000400534T patent/GR3032842T3/el not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FI935408A (fi) | 1993-12-02 |
| CA2110256A1 (en) | 1992-12-10 |
| US6479050B1 (en) | 2002-11-12 |
| SK280475B6 (sk) | 2000-02-14 |
| DE69230495T2 (de) | 2000-06-21 |
| PL170970B1 (pl) | 1997-02-28 |
| AU657763B2 (en) | 1995-03-23 |
| ATE188247T1 (de) | 2000-01-15 |
| EP0587711B1 (en) | 1999-12-29 |
| WO1992021749A1 (en) | 1992-12-10 |
| EP0587711A1 (en) | 1994-03-23 |
| JP3338446B2 (ja) | 2002-10-28 |
| GR3032842T3 (en) | 2000-07-31 |
| JPH06508516A (ja) | 1994-09-29 |
| DK0587711T3 (da) | 2000-05-08 |
| NO934379L (no) | 1994-01-31 |
| PL297843A1 (en) | 1993-11-02 |
| NO934379D0 (no) | 1993-12-02 |
| SK134893A3 (en) | 1994-05-11 |
| ES2139599T3 (es) | 2000-02-16 |
| AU1929392A (en) | 1993-01-08 |
| HU9303417D0 (en) | 1994-03-28 |
| FI935408A0 (fi) | 1993-12-02 |
| HUT70260A (en) | 1995-09-28 |
| NO314549B1 (no) | 2003-04-07 |
| CZ255793A3 (en) | 1994-04-13 |
| CZ283936B6 (cs) | 1998-07-15 |
| HU218045B (hu) | 2000-05-28 |
| DE69230495D1 (de) | 2000-02-03 |
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