FI109797B - Menetelmä 10-desasetyylibakkatiini III:n valmistamiseksi käyttäen marjakuusta raaka-aineena - Google Patents

Menetelmä 10-desasetyylibakkatiini III:n valmistamiseksi käyttäen marjakuusta raaka-aineena Download PDF

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Publication number
FI109797B
FI109797B FI951590A FI951590A FI109797B FI 109797 B FI109797 B FI 109797B FI 951590 A FI951590 A FI 951590A FI 951590 A FI951590 A FI 951590A FI 109797 B FI109797 B FI 109797B
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FI
Finland
Prior art keywords
taxus
iii
methyl
eller
acetate
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Application number
FI951590A
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English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI951590A0 (fi
FI951590A (fi
Inventor
Rodolphe Margraff
Original Assignee
Rhone Poulenc Rorer Sa
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Application filed by Rhone Poulenc Rorer Sa filed Critical Rhone Poulenc Rorer Sa
Publication of FI951590A0 publication Critical patent/FI951590A0/fi
Publication of FI951590A publication Critical patent/FI951590A/fi
Application granted granted Critical
Publication of FI109797B publication Critical patent/FI109797B/fi

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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D305/00—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms
    • C07D305/14—Heterocyclic compounds containing four-membered rings having one oxygen atom as the only ring hetero atoms condensed with carbocyclic rings or ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

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  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Epoxy Compounds (AREA)
  • Medicines Containing Plant Substances (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Extraction Or Liquid Replacement (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
FI951590A 1992-10-05 1995-04-04 Menetelmä 10-desasetyylibakkatiini III:n valmistamiseksi käyttäen marjakuusta raaka-aineena FI109797B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
FR9211745 1992-10-05
FR9211745A FR2696462B1 (fr) 1992-10-05 1992-10-05 Procédé d'obtention de la désacétyl-10 baccatine III.
PCT/FR1993/000971 WO1994007881A1 (fr) 1992-10-05 1993-10-04 Procede d'obtention de la desacetyl-10 baccatine iii
FR9300971 1993-10-04

Publications (3)

Publication Number Publication Date
FI951590A0 FI951590A0 (fi) 1995-04-04
FI951590A FI951590A (fi) 1995-04-04
FI109797B true FI109797B (fi) 2002-10-15

Family

ID=9434123

Family Applications (1)

Application Number Title Priority Date Filing Date
FI951590A FI109797B (fi) 1992-10-05 1995-04-04 Menetelmä 10-desasetyylibakkatiini III:n valmistamiseksi käyttäen marjakuusta raaka-aineena

Country Status (30)

Country Link
US (2) US5393896A (ja)
EP (1) EP0663909B1 (ja)
JP (1) JP3299753B2 (ja)
KR (1) KR100301238B1 (ja)
CN (1) CN1041310C (ja)
AT (1) ATE147381T1 (ja)
AU (1) AU680440B2 (ja)
CA (2) CA2470124C (ja)
CZ (2) CZ286452B6 (ja)
DE (1) DE69307333T2 (ja)
DK (1) DK0663909T3 (ja)
EE (1) EE03124B1 (ja)
ES (1) ES2095672T3 (ja)
FI (1) FI109797B (ja)
FR (1) FR2696462B1 (ja)
GE (1) GEP19981433B (ja)
GR (1) GR3022229T3 (ja)
HU (1) HU225969B1 (ja)
LT (1) LT3465B (ja)
LV (1) LV10620B (ja)
MX (1) MX9305770A (ja)
NO (1) NO310414B1 (ja)
NZ (1) NZ256449A (ja)
PL (1) PL173993B1 (ja)
RU (1) RU2108330C1 (ja)
SK (1) SK280335B6 (ja)
TW (1) TW404944B (ja)
UA (1) UA40601C2 (ja)
WO (1) WO1994007881A1 (ja)
ZA (1) ZA937312B (ja)

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FR2736355B1 (fr) * 1995-07-07 1997-11-07 Pf Medicament Procede d'extraction et d'isolement de la 10-desacetylbaccatine iii
US5965752A (en) * 1996-08-23 1999-10-12 Institut National De La Recherche Scientifique Preparative scale isolation and purification of taxanes
DE69812395T2 (de) 1997-08-21 2004-02-05 Florida State University, Tallahassee Verfahren zur synthese von taxanen
US6066748A (en) * 1997-12-17 2000-05-23 Han; Man Woo Process of extracting TAXOL® from taxus cuspidata
ATE219070T1 (de) * 1998-01-14 2002-06-15 Bristol Myers Squibb Co Neue kristallkomplexe von baccatin iii mit imidazol, 2-methylimidazol or isopropanol
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Family Cites Families (12)

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Publication number Priority date Publication date Assignee Title
FR2601675B1 (fr) * 1986-07-17 1988-09-23 Rhone Poulenc Sante Derives du taxol, leur preparation et les compositions pharmaceutiques qui les contiennent
FR2601676B1 (fr) 1986-07-17 1988-09-23 Rhone Poulenc Sante Procede de preparation du taxol et du desacetyl-10 taxol
FR2629818B1 (fr) * 1988-04-06 1990-11-16 Centre Nat Rech Scient Procede de preparation du taxol
FR2629819B1 (fr) 1988-04-06 1990-11-16 Rhone Poulenc Sante Procede de preparation de derives de la baccatine iii et de la desacetyl-10 baccatine iii
US5019504A (en) * 1989-03-23 1991-05-28 The United States Of America As Represented By The Secretary Of Agriculture Production of taxol or taxol-like compounds in cell culture
US5175315A (en) * 1989-05-31 1992-12-29 Florida State University Method for preparation of taxol using β-lactam
US5136060A (en) * 1989-11-14 1992-08-04 Florida State University Method for preparation of taxol using an oxazinone
US5380916A (en) 1990-11-02 1995-01-10 University Of Florida Method for the isolation and purification of taxane derivatives
MX9102128A (es) 1990-11-23 1992-07-08 Rhone Poulenc Rorer Sa Derivados de taxano,procedimiento para su preparacion y composicion farmaceutica que los contiene
US5279953A (en) * 1992-06-24 1994-01-18 Esca Genetics Corporation In vivo production of taxanes
FR2696463B1 (fr) * 1992-10-05 1994-11-25 Rhone Poulenc Rorer Sa Procédé d'obtention de la désacétyl-10 baccatine III.
FR2703049B1 (fr) * 1993-03-22 1995-04-21 Rhone Poulenc Rorer Sa Procédé de purification des taxoïdes.

Also Published As

Publication number Publication date
DK0663909T3 (ja) 1997-01-27
ZA937312B (en) 1994-04-25
JPH08501791A (ja) 1996-02-27
AU680440B2 (en) 1997-07-31
TW404944B (en) 2000-09-11
MX9305770A (es) 1994-05-31
CA2146248C (fr) 2006-12-12
SK43195A3 (en) 1995-08-09
GEP19981433B (en) 1998-10-30
SK280335B6 (sk) 1999-12-10
US5736366A (en) 1998-04-07
KR950703549A (ko) 1995-09-20
CZ84495A3 (en) 1995-09-13
EP0663909B1 (fr) 1997-01-08
PL308243A1 (en) 1995-07-24
LT3465B (en) 1995-10-25
ATE147381T1 (de) 1997-01-15
ES2095672T3 (es) 1997-02-16
DE69307333T2 (de) 1997-04-30
FR2696462A1 (fr) 1994-04-08
NO951281L (no) 1995-04-03
NO951281D0 (no) 1995-04-03
CA2470124A1 (fr) 1994-04-14
KR100301238B1 (ko) 2001-11-22
FI951590A0 (fi) 1995-04-04
CN1085552A (zh) 1994-04-20
HU225969B1 (en) 2008-01-28
LV10620A (lv) 1995-04-20
HU9500969D0 (en) 1995-06-28
UA40601C2 (uk) 2001-08-15
RU95110662A (ru) 1996-12-27
JP3299753B2 (ja) 2002-07-08
RU2108330C1 (ru) 1998-04-10
AU5115493A (en) 1994-04-26
CN1041310C (zh) 1998-12-23
FR2696462B1 (fr) 1994-11-25
US5393896A (en) 1995-02-28
PL173993B1 (pl) 1998-05-29
LTIP1398A (en) 1994-11-25
CZ286593B6 (cs) 2000-05-17
HUT72678A (en) 1996-05-28
CA2470124C (fr) 2007-08-07
DE69307333D1 (de) 1997-02-20
FI951590A (fi) 1995-04-04
NO310414B1 (no) 2001-07-02
CZ286452B6 (en) 2000-04-12
NZ256449A (en) 1996-09-25
LV10620B (en) 1995-10-20
WO1994007881A1 (fr) 1994-04-14
EE03124B1 (et) 1998-10-15
EP0663909A1 (fr) 1995-07-26
CA2146248A1 (fr) 1994-04-14
GR3022229T3 (en) 1997-04-30

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