FI107156B - Menetelmä farmakologisesti aktiivisten indoli-2,3-dioni-3-oksiimijohdannaisten valmistamiseksi - Google Patents
Menetelmä farmakologisesti aktiivisten indoli-2,3-dioni-3-oksiimijohdannaisten valmistamiseksi Download PDFInfo
- Publication number
- FI107156B FI107156B FI940889A FI940889A FI107156B FI 107156 B FI107156 B FI 107156B FI 940889 A FI940889 A FI 940889A FI 940889 A FI940889 A FI 940889A FI 107156 B FI107156 B FI 107156B
- Authority
- FI
- Finland
- Prior art keywords
- formula
- compound
- dione
- hydrogen
- oxime
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/06—Antimigraine agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C205/00—Compounds containing nitro groups bound to a carbon skeleton
- C07C205/45—Compounds containing nitro groups bound to a carbon skeleton the carbon skeleton being further substituted by at least one doubly—bound oxygen atom, not being part of a —CHO group
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
- C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
- C07D491/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Neurosurgery (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Psychiatry (AREA)
- Hospice & Palliative Care (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Hydrogenated Pyridines (AREA)
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US75116591A | 1991-08-28 | 1991-08-28 | |
| US75116591 | 1991-08-28 | ||
| US83185192A | 1992-02-05 | 1992-02-05 | |
| US83185192 | 1992-02-05 | ||
| EP9201999 | 1992-08-27 | ||
| PCT/EP1992/001999 WO1993005043A1 (en) | 1991-08-28 | 1992-08-27 | Novel isatinoxime derivatives, their preparation and use |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI940889A0 FI940889A0 (fi) | 1994-02-25 |
| FI940889A FI940889A (fi) | 1994-02-25 |
| FI107156B true FI107156B (fi) | 2001-06-15 |
Family
ID=27115380
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI940889A FI107156B (fi) | 1991-08-28 | 1994-02-25 | Menetelmä farmakologisesti aktiivisten indoli-2,3-dioni-3-oksiimijohdannaisten valmistamiseksi |
Country Status (18)
| Country | Link |
|---|---|
| EP (1) | EP0529636B1 (ru) |
| JP (1) | JP3170584B2 (ru) |
| KR (1) | KR100277481B1 (ru) |
| AT (1) | ATE181552T1 (ru) |
| AU (1) | AU655672B2 (ru) |
| CA (1) | CA2076948C (ru) |
| CZ (1) | CZ282759B6 (ru) |
| DE (1) | DE69229461T2 (ru) |
| DK (1) | DK0529636T3 (ru) |
| FI (1) | FI107156B (ru) |
| GE (1) | GEP20002329B (ru) |
| HU (2) | HUT70753A (ru) |
| MX (1) | MX9204914A (ru) |
| NO (1) | NO301117B1 (ru) |
| PL (1) | PL170920B1 (ru) |
| RU (1) | RU2114827C1 (ru) |
| SK (1) | SK280578B6 (ru) |
| WO (1) | WO1993005043A1 (ru) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0664807B1 (en) | 1992-10-13 | 1997-09-10 | Warner-Lambert Company | Quinoxalinedione derivatives as eaa antagonists |
| US5843945A (en) * | 1993-05-13 | 1998-12-01 | Neurosearch A/S | AMPA antagonists and a method of treatment |
| ATE161259T1 (de) * | 1993-05-13 | 1998-01-15 | Neurosearch As | Ampa antagonisten und behandlungsmethode |
| DK81593D0 (da) * | 1993-07-07 | 1993-07-07 | Neurosearch As | Nye isatinoximderivater, deres fremstilling og anvendelse |
| DE69514533T2 (de) * | 1994-09-14 | 2000-07-06 | Neurosearch A/S, Ballerup | Kondensierte indole und chinoxalinderivate, ihre herstellung und verwendung als glutamatantagonisten |
| US5917053A (en) * | 1994-09-14 | 1999-06-29 | Neurosearch A/S | Indole-2,3-dione-3-oxime derivatives, their preparation and use |
| UA54403C2 (ru) * | 1996-10-01 | 2003-03-17 | Н'Юросерч А/С | Производные индол-2,3-дион-3-оксима, фармацевтическая композиция, способ лечения расстройства или заболевания млекопитающих, в том числе человека и способ получения производных индол-2,3-дион-3-оксима |
| FR2768624B1 (fr) * | 1997-09-25 | 1999-11-12 | Oreal | Utilisation d'un inhibiteur d'acides amines excitateurs dans une composition cosmetique ou dermatologique pour peaux sensibles et composition obtenue |
| ATE420636T1 (de) | 1999-05-19 | 2009-01-15 | Painceptor Pharma Corp | Hemmer der protonenabhängigen kationenkanäle und deren verwendung in der behandlung von ischemiebedingten erkrankungen |
| CN1298704C (zh) | 2000-01-24 | 2007-02-07 | 神经研究公司 | 具有神经营养活性的靛红衍生物 |
| JP4505410B2 (ja) | 2002-10-29 | 2010-07-21 | サングキュンクワン ユニヴァースィティ | モルヒネへの心理的依存又は耐性を防止及び処置するのに有効成分としてベルベリンを含有する医薬組成物 |
| CA2630617C (en) | 2005-11-23 | 2014-03-25 | Painceptor Pharma Corporation | Compositions and methods for modulating gated ion channels |
| CN104995171B (zh) * | 2012-12-19 | 2018-02-06 | 拜耳作物科学股份公司 | 作为杀真菌剂的二氟甲基‑烟碱‑茚满基甲酰胺 |
| US9815768B2 (en) * | 2014-02-28 | 2017-11-14 | Sumitomo Chemical Company, Limited | Method for producing 2-(halogenomethyl)-3-methylnitrobenzene |
| WO2017160933A1 (en) | 2016-03-17 | 2017-09-21 | Fmc Corporation | Process for converting s-enantiomer to its racemic form |
| CN112266368B (zh) * | 2017-11-15 | 2024-03-19 | 中山光禾医疗科技有限公司 | 光交联水凝胶材料的制备、原料、产品及应用 |
| CN108912127B (zh) * | 2018-08-27 | 2019-12-10 | 青岛农业大学 | 一种基于靛红骨架的苯并[b,e]氮杂卓化合物及其制备方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| IE69677B1 (en) * | 1989-12-11 | 1996-10-02 | Neurosearch As | Isatine derivatives their preparation and use |
-
1992
- 1992-08-26 CA CA002076948A patent/CA2076948C/en not_active Expired - Fee Related
- 1992-08-26 MX MX9204914A patent/MX9204914A/es not_active IP Right Cessation
- 1992-08-27 AU AU24820/92A patent/AU655672B2/en not_active Ceased
- 1992-08-27 AT AT92114654T patent/ATE181552T1/de not_active IP Right Cessation
- 1992-08-27 DK DK92114654T patent/DK0529636T3/da active
- 1992-08-27 WO PCT/EP1992/001999 patent/WO1993005043A1/en active IP Right Grant
- 1992-08-27 KR KR1019940700676A patent/KR100277481B1/ko not_active IP Right Cessation
- 1992-08-27 RU RU94019425/04A patent/RU2114827C1/ru not_active IP Right Cessation
- 1992-08-27 JP JP50493393A patent/JP3170584B2/ja not_active Expired - Fee Related
- 1992-08-27 GE GEAP19922683A patent/GEP20002329B/en unknown
- 1992-08-27 EP EP92114654A patent/EP0529636B1/en not_active Expired - Lifetime
- 1992-08-27 SK SK238-94A patent/SK280578B6/sk unknown
- 1992-08-27 HU HU9400595A patent/HUT70753A/hu unknown
- 1992-08-27 DE DE69229461T patent/DE69229461T2/de not_active Expired - Lifetime
- 1992-08-27 CZ CZ94395A patent/CZ282759B6/cs not_active IP Right Cessation
- 1992-08-27 PL PL92302584A patent/PL170920B1/pl unknown
-
1994
- 1994-02-25 NO NO940676A patent/NO301117B1/no unknown
- 1994-02-25 FI FI940889A patent/FI107156B/fi active
-
1995
- 1995-06-21 HU HU95P/P00323P patent/HU211632A9/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| AU655672B2 (en) | 1995-01-05 |
| GEP20002329B (en) | 2000-12-25 |
| CA2076948C (en) | 2002-04-16 |
| HU9400595D0 (en) | 1994-05-30 |
| DK0529636T3 (da) | 1999-12-13 |
| HUT70753A (en) | 1995-10-30 |
| EP0529636B1 (en) | 1999-06-23 |
| SK23894A3 (en) | 1994-12-07 |
| RU2114827C1 (ru) | 1998-07-10 |
| FI940889A0 (fi) | 1994-02-25 |
| ATE181552T1 (de) | 1999-07-15 |
| KR100277481B1 (ko) | 2001-02-01 |
| JP3170584B2 (ja) | 2001-05-28 |
| NO940676D0 (no) | 1994-02-25 |
| EP0529636A1 (en) | 1993-03-03 |
| CZ39594A3 (en) | 1994-11-16 |
| DE69229461T2 (de) | 1999-10-21 |
| WO1993005043A1 (en) | 1993-03-18 |
| PL170920B1 (pl) | 1997-02-28 |
| DE69229461D1 (de) | 1999-07-29 |
| CA2076948A1 (en) | 1993-03-01 |
| NO940676L (ru) | 1994-04-27 |
| FI940889A (fi) | 1994-02-25 |
| AU2482092A (en) | 1993-04-05 |
| CZ282759B6 (cs) | 1997-09-17 |
| SK280578B6 (sk) | 2000-04-10 |
| JPH06510056A (ja) | 1994-11-10 |
| NO301117B1 (no) | 1997-09-15 |
| HU211632A9 (en) | 1995-12-28 |
| MX9204914A (es) | 1993-07-01 |
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