FI106020B - Menetelmä 3,4-disubstituoitujen 2-atsetidinonien valmistamiseksi ja menetelmässä käytettävä välituote - Google Patents

Menetelmä 3,4-disubstituoitujen 2-atsetidinonien valmistamiseksi ja menetelmässä käytettävä välituote Download PDF

Info

Publication number
FI106020B
FI106020B FI941894A FI941894A FI106020B FI 106020 B FI106020 B FI 106020B FI 941894 A FI941894 A FI 941894A FI 941894 A FI941894 A FI 941894A FI 106020 B FI106020 B FI 106020B
Authority
FI
Finland
Prior art keywords
phenyl
mixture
solution
alkyl
aqueous
Prior art date
Application number
FI941894A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI941894A0 (fi
FI941894A (fi
Inventor
Purushotham Vemishetti
Roberto Droghini
Allan W Rey
Original Assignee
Squibb Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/165,610 external-priority patent/US5412092A/en
Application filed by Squibb Bristol Myers Co filed Critical Squibb Bristol Myers Co
Publication of FI941894A0 publication Critical patent/FI941894A0/fi
Publication of FI941894A publication Critical patent/FI941894A/fi
Application granted granted Critical
Publication of FI106020B publication Critical patent/FI106020B/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D205/00Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom
    • C07D205/02Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings
    • C07D205/06Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D205/08Heterocyclic compounds containing four-membered rings with one nitrogen atom as the only ring hetero atom not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with one oxygen atom directly attached in position 2, e.g. beta-lactams
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/14Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing three or more hetero rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H17/00Compounds containing heterocyclic radicals directly attached to hetero atoms of saccharide radicals
    • C07H17/02Heterocyclic radicals containing only nitrogen as ring hetero atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI941894A 1993-04-23 1994-04-22 Menetelmä 3,4-disubstituoitujen 2-atsetidinonien valmistamiseksi ja menetelmässä käytettävä välituote FI106020B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US5243493A 1993-04-23 1993-04-23
US5243493 1993-04-23
US08/165,610 US5412092A (en) 1993-04-23 1993-12-13 N-substituted 2-azetidinones
US16561093 1993-12-13

Publications (3)

Publication Number Publication Date
FI941894A0 FI941894A0 (fi) 1994-04-22
FI941894A FI941894A (fi) 1994-10-24
FI106020B true FI106020B (fi) 2000-11-15

Family

ID=26730594

Family Applications (1)

Application Number Title Priority Date Filing Date
FI941894A FI106020B (fi) 1993-04-23 1994-04-22 Menetelmä 3,4-disubstituoitujen 2-atsetidinonien valmistamiseksi ja menetelmässä käytettävä välituote

Country Status (14)

Country Link
US (1) US6008347A (pl)
EP (1) EP0627418A1 (pl)
JP (1) JPH072763A (pl)
CN (1) CN1063439C (pl)
AU (1) AU677986B2 (pl)
CA (1) CA2120221A1 (pl)
CZ (1) CZ286105B6 (pl)
FI (1) FI106020B (pl)
HU (1) HU216634B (pl)
IL (1) IL109356A (pl)
NO (1) NO180444C (pl)
NZ (1) NZ260322A (pl)
PL (1) PL178240B1 (pl)
RU (1) RU2132844C1 (pl)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NZ321766A (en) * 1995-10-31 1999-07-29 Schering Corp Sugar-substituted 2-azetidinones useful as hypocholesterolemic agents
EP0933360A1 (en) 1997-12-22 1999-08-04 Pharmachemie B.V. Synthesis of new beta-lactams

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS61207386A (ja) * 1985-03-12 1986-09-13 Takeda Chem Ind Ltd アゼチジノン誘導体および製造法
IL99658A0 (en) * 1990-10-15 1992-08-18 Merck & Co Inc Substituted azetidinones and pharmaceutical compositions containing them
CA2147129A1 (en) * 1992-10-27 1994-05-11 James B. Doherty New substituted azetidinones as anti-inflammatory and antidegenerative agents
ZA94128B (en) * 1993-02-01 1994-08-19 Univ New York State Res Found Process for the preparation of taxane derivatives and betalactam intermediates therefor

Also Published As

Publication number Publication date
AU6061194A (en) 1994-10-27
CZ286105B6 (cs) 2000-01-12
IL109356A (en) 1998-01-04
NO180444B (no) 1997-01-13
HU216634B (hu) 1999-07-28
RU2132844C1 (ru) 1999-07-10
JPH072763A (ja) 1995-01-06
CN1097415A (zh) 1995-01-18
IL109356A0 (en) 1994-07-31
HU9401167D0 (en) 1994-08-29
NO941397D0 (no) 1994-04-18
NZ260322A (en) 1995-09-26
EP0627418A1 (en) 1994-12-07
CZ96694A3 (en) 1994-12-15
CN1063439C (zh) 2001-03-21
FI941894A0 (fi) 1994-04-22
PL178240B1 (pl) 2000-03-31
NO941397L (no) 1994-10-24
US6008347A (en) 1999-12-28
AU677986B2 (en) 1997-05-15
CA2120221A1 (en) 1994-10-24
FI941894A (fi) 1994-10-24
HUT69373A (en) 1995-09-28
NO180444C (no) 1997-04-23

Similar Documents

Publication Publication Date Title
US5412092A (en) N-substituted 2-azetidinones
ES2354728T3 (es) Procedimiento para la producción de ezetimiba e intermedios utilizados en dicho procedimiento.
CA2118867A1 (en) 2-debenzoyl-2-acyl taxol derivatives and methods for making same
CA2161328A1 (en) Delta 6,7-taxols antineoplastic use and pharmaceutical compositions containing them
CA2569498C (en) Semi-synthesis of taxane intermediates and their conversion to paclitaxel and docetaxel
CA2501805C (en) Novel taxanes and methods related to use and preparation thereof
LV13023B (en) 7-halo- and 7(beta),8(beta)-methano-taxols, antineoplastic use and pharmaceutical compositions containing them
FI110942B (fi) Menetelmä terapeuttisesti käyttökelpoisten fluoritaksolien valmistamiseksi
FI106020B (fi) Menetelmä 3,4-disubstituoitujen 2-atsetidinonien valmistamiseksi ja menetelmässä käytettävä välituote
CA2197467C (en) Method for the preparation of taxol and its derivatives
ZA200501234B (en) Process for preparing paclitaxel
KR20040097245A (ko) 탁솔의 제조 방법
EP0861838A2 (en) Process and intermediates for preparing cryptophycin compounds
FI94252B (fi) Menetelmä peneemien valmistamiseksi
JP2001500484A (ja) 医薬化合物の製造法
CA2672911C (en) Semi-synthetic process for the preparation of taxane derivatives
KR20040099963A (ko) 키랄성 2-아제티디논 화합물, 이의 제조방법 및 이의 용도
JP2013523863A (ja) イソセリン誘導体の調製方法
JPS61268666A (ja) β−ラクタム化合物
MXPA99007770A (en) Process for preparing pharmaceutical compounds
AU7238200A (en) Production method of optically active transvinylsulfide alcohol