ES8704497A1 - Un procedimiento para la preparacion de oxindal-carboxamidas triciclicas. - Google Patents

Un procedimiento para la preparacion de oxindal-carboxamidas triciclicas.

Info

Publication number
ES8704497A1
ES8704497A1 ES546377A ES546377A ES8704497A1 ES 8704497 A1 ES8704497 A1 ES 8704497A1 ES 546377 A ES546377 A ES 546377A ES 546377 A ES546377 A ES 546377A ES 8704497 A1 ES8704497 A1 ES 8704497A1
Authority
ES
Spain
Prior art keywords
carboxamides
procedure
tricyclic
formula
oxindal
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES546377A
Other languages
English (en)
Spanish (es)
Other versions
ES546377A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Pfizer Inc
Original Assignee
Pfizer Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer Inc filed Critical Pfizer Inc
Publication of ES546377A0 publication Critical patent/ES546377A0/es
Publication of ES8704497A1 publication Critical patent/ES8704497A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/56—Ring systems containing three or more rings
    • C07D209/58—[b]- or [c]-condensed
    • C07D209/70—[b]- or [c]-condensed containing carbocyclic rings other than six-membered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Rheumatology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pain & Pain Management (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Medicinal Preparation (AREA)
  • Polymers With Sulfur, Phosphorus Or Metals In The Main Chain (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Filling Or Discharging Of Gas Storage Vessels (AREA)
  • Optical Fibers, Optical Fiber Cores, And Optical Fiber Bundles (AREA)
ES546377A 1984-08-24 1985-08-23 Un procedimiento para la preparacion de oxindal-carboxamidas triciclicas. Expired ES8704497A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1984/001371 WO1986001510A1 (en) 1984-08-24 1984-08-24 Tricyclic oxindole antiinflammatory agents

Publications (2)

Publication Number Publication Date
ES546377A0 ES546377A0 (es) 1987-04-01
ES8704497A1 true ES8704497A1 (es) 1987-04-01

Family

ID=22182243

Family Applications (2)

Application Number Title Priority Date Filing Date
ES546377A Expired ES8704497A1 (es) 1984-08-24 1985-08-23 Un procedimiento para la preparacion de oxindal-carboxamidas triciclicas.
ES552044A Expired ES8706116A1 (es) 1984-08-24 1986-02-14 Un procedimiento para la preparacion de oxindol-carboxamidas triciclicas

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES552044A Expired ES8706116A1 (es) 1984-08-24 1986-02-14 Un procedimiento para la preparacion de oxindol-carboxamidas triciclicas

Country Status (21)

Country Link
US (1) US4695571A (oth)
EP (1) EP0173520B1 (oth)
JP (1) JPS6157554A (oth)
KR (1) KR870001144B1 (oth)
AT (1) ATE49211T1 (oth)
AU (1) AU553859B2 (oth)
CA (1) CA1244427A (oth)
DE (1) DE3575140D1 (oth)
DK (1) DK160098C (oth)
EG (1) EG17287A (oth)
ES (2) ES8704497A1 (oth)
FI (1) FI79319C (oth)
GR (1) GR852026B (oth)
HU (2) HU203238B (oth)
IE (1) IE58739B1 (oth)
IL (1) IL76175A (oth)
PH (1) PH23065A (oth)
PL (2) PL147395B1 (oth)
PT (1) PT81004B (oth)
WO (1) WO1986001510A1 (oth)
ZA (1) ZA856403B (oth)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3531678A1 (de) * 1985-09-05 1987-03-12 Boehringer Mannheim Gmbh Neue pyrrolo-benzimidazole, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
JPS63223492A (ja) * 1987-03-11 1988-09-16 Okawara Mfg Co Ltd 熱交換器
WO1990008145A1 (en) * 1989-01-10 1990-07-26 Pfizer Inc. Anti-inflammatory 1-heteroaryl-3-acyl-2-oxindoles
US5128352A (en) * 1989-01-10 1992-07-07 Pfizer Inc. Anti-inflammatory 1-heteroaryl-oxindole-3-carboxamides
US5300655A (en) * 1989-04-18 1994-04-05 Pfizer Inc. 2-carboxy-thiophene derivatives
US5047554A (en) * 1989-04-18 1991-09-10 Pfizer Inc. 3-substituted-2-oxindole derivatives
JPH04217684A (ja) * 1990-05-30 1992-08-07 Shionogi & Co Ltd アルド−ス還元酵素阻害物質
DE4027592A1 (de) * 1990-08-31 1992-03-05 Beiersdorf Ag Neue pyrrolobenzimidazole, imidazobenzoxazinone und imidazochinolone, verfahren zu ihrer herstellung und ihre verwendung sowie die verbindungen enthaltende zubereitungen
JP4202250B2 (ja) 2001-07-25 2008-12-24 バイオマリン ファーマシューティカル インコーポレイテッド 血液脳関門輸送を調節するための組成物および方法
WO2005041957A1 (en) * 2003-10-29 2005-05-12 Pfizer Products Inc. Oxindole derivatives and their use as phosphodiesterase type 2 inhibitors
EP2671507A3 (en) 2005-04-28 2014-02-19 Proteus Digital Health, Inc. Pharma-informatics system
MX2009002893A (es) 2006-09-18 2009-07-10 Raptor Pharmaceutical Inc Tratamiento de trastornos hepaticos mediante la administracion de conjugados de la proteina asociada al receptor (rap).
CA2752373C (en) 2009-02-20 2017-10-10 To-Bbb Holding B.V. Glutathione-based drug delivery system
IL255113B (en) 2009-05-06 2022-09-01 Laboratory Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE756447A (fr) * 1969-10-15 1971-03-22 Pfizer Oxindolecarboxamides
US3749731A (en) * 1971-07-08 1973-07-31 Warner Lambert Co 2-oxo-n-(2-thiazolyl)-3-indoline-carboxamide
US4644005A (en) * 1984-10-31 1987-02-17 Pfizer Inc. Oxindole antiinflammatory agents

Also Published As

Publication number Publication date
US4695571A (en) 1987-09-22
DE3575140D1 (de) 1990-02-08
HUT47580A (en) 1989-03-28
HU203238B (en) 1991-06-28
EP0173520A3 (en) 1986-05-14
DK382685D0 (da) 1985-08-23
AU4663785A (en) 1986-02-27
ES546377A0 (es) 1987-04-01
PH23065A (en) 1989-03-27
FI79319C (fi) 1989-12-11
ATE49211T1 (de) 1990-01-15
PL255089A1 (en) 1986-12-30
EP0173520B1 (en) 1990-01-03
PT81004B (pt) 1987-12-30
KR870002143A (ko) 1987-03-30
FI861704A0 (fi) 1986-04-23
HU203350B (en) 1991-07-29
EP0173520A2 (en) 1986-03-05
IE852081L (en) 1986-02-24
ZA856403B (en) 1987-04-29
EG17287A (en) 1993-02-28
DK160098B (da) 1991-01-28
GR852026B (oth) 1985-12-19
ES8706116A1 (es) 1987-06-01
IL76175A0 (en) 1985-12-31
IL76175A (en) 1989-08-15
PL147395B1 (en) 1989-05-31
KR870001144B1 (ko) 1987-06-11
AU553859B2 (en) 1986-07-31
PL147393B1 (en) 1989-05-31
JPH0450316B2 (oth) 1992-08-13
IE58739B1 (en) 1993-11-03
ES552044A0 (es) 1987-06-01
WO1986001510A1 (en) 1986-03-13
FI861704A7 (fi) 1986-04-23
JPS6157554A (ja) 1986-03-24
PT81004A (en) 1985-09-01
CA1244427A (en) 1988-11-08
DK382685A (da) 1986-02-25
DK160098C (da) 1991-06-24
FI79319B (fi) 1989-08-31
HU902020D0 (en) 1990-07-28

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20020401