ES8702786A1 - Procedimiento para la obtencion de comprimidos de sustancia activa farmaceutica, de rapida desintegracion - Google Patents
Procedimiento para la obtencion de comprimidos de sustancia activa farmaceutica, de rapida desintegracionInfo
- Publication number
- ES8702786A1 ES8702786A1 ES541513A ES541513A ES8702786A1 ES 8702786 A1 ES8702786 A1 ES 8702786A1 ES 541513 A ES541513 A ES 541513A ES 541513 A ES541513 A ES 541513A ES 8702786 A1 ES8702786 A1 ES 8702786A1
- Authority
- ES
- Spain
- Prior art keywords
- pharmaceutical active
- disintegrating
- quick
- active substances
- containing pharmaceutical
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
Landscapes
- Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Engineering & Computer Science (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Medicinal Preparation (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
METODO DE PREPARACION DE COMPRIMIDOS QUE CONTIENEN SUSTANCIAS ACTIVAS FARMACEUTICAS. CONSISTE EN REVESTIR POR PULVERIZACION UNA SUSTANCIA ACTIVA FARMACEUTICA, EN FORMA GRANULADA, CON UNA DISPERSION ACUOSA DE UN POLI(HBMET)-ACRILATO DE (METBETILO) Y DE UNA ETILCELULOSA, AMBOS INSOLUBLES EN AGUA, EN LA PROPORCION DE ACRILATO A ETILCELULOSA DE 2,5:1 A 5:1; MEZCLAR CON UN AGENTE DISGREGANTE Y AGLUTINANTE, TAL COMO POLIVINILPOLIPIRROLIDONA TRANSVERSALMENTE RETICULADA O UNA MEZCLA DE ESTA Y CELULOSA MICROCRISTALINA. TIENE APLICACIONES PARA PREPARAR COMPRIMIDOS QUE CONTIENEN CLORURO POTADISO O SALES DE LITIO PARA EL TRATAMIENTO CON CIURETICOS SALIURETICOS O EN LA PSICOTERAPIA, RESPECTIVAMENTE.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CH1465/84A CH658188A5 (de) | 1984-03-23 | 1984-03-23 | Lagerstabile schnellzerfallende pharmazeutische presslinge. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES8702786A1 true ES8702786A1 (es) | 1987-01-16 |
ES541513A0 ES541513A0 (es) | 1987-01-16 |
Family
ID=4211107
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES541513A Expired ES8702786A1 (es) | 1984-03-23 | 1985-03-22 | Procedimiento para la obtencion de comprimidos de sustancia activa farmaceutica, de rapida desintegracion |
Country Status (26)
Country | Link |
---|---|
US (1) | US4666703A (es) |
JP (1) | JPS60209518A (es) |
AT (1) | AT394310B (es) |
AU (1) | AU579355B2 (es) |
BE (1) | BE901994A (es) |
CA (1) | CA1239348A (es) |
CH (1) | CH658188A5 (es) |
DE (1) | DE3510129A1 (es) |
DK (1) | DK162375C (es) |
ES (1) | ES8702786A1 (es) |
FI (1) | FI82187C (es) |
FR (1) | FR2561524B1 (es) |
GB (1) | GB2157170B (es) |
GR (1) | GR850717B (es) |
HK (1) | HK73090A (es) |
IE (1) | IE57954B1 (es) |
IL (1) | IL74666A (es) |
IT (1) | IT1182723B (es) |
LU (1) | LU85817A1 (es) |
NL (1) | NL8500856A (es) |
NO (1) | NO170125C (es) |
NZ (1) | NZ211537A (es) |
PT (1) | PT80147B (es) |
SE (1) | SE8501370L (es) |
SG (1) | SG46890G (es) |
ZA (1) | ZA852160B (es) |
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2059260A1 (es) * | 1992-10-06 | 1994-11-01 | Espanola Prod Quimicos | Procedimiento de preparacion de comprimidos conteniendo diclofenaco; dispersables en agua. |
Families Citing this family (67)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
AT350735B (de) * | 1976-08-06 | 1979-06-11 | Hoffmann La Roche | Verfahren zur herstellung von neuen ribo- furanosyl-imidazolderivaten |
CA1270765A (en) * | 1985-02-19 | 1990-06-26 | Charles Hsiao | Controlled release potassium chloride |
IE59066B1 (en) * | 1985-02-19 | 1993-12-15 | Key Pharma | Controlled release potassium chloride |
GB8519310D0 (en) * | 1985-07-31 | 1985-09-04 | Zyma Sa | Granular active substances |
US4971791A (en) * | 1985-08-26 | 1990-11-20 | The Procter & Gamble Company | Taste masking compositions |
GB8521494D0 (en) * | 1985-08-29 | 1985-10-02 | Zyma Sa | Controlled release tablet |
US5624683A (en) * | 1986-08-06 | 1997-04-29 | Eisai Co., Ltd. | Sustained-release multi-granule tablet |
IT1197316B (it) * | 1986-10-01 | 1988-11-30 | Proter Spa | Formulazione galenica ad uso orale di derivati della reina a lento rilascio per impiego terapeutico |
US4800087A (en) * | 1986-11-24 | 1989-01-24 | Mehta Atul M | Taste-masked pharmaceutical compositions |
GB8628359D0 (en) * | 1986-11-27 | 1986-12-31 | Zyma Sa | Galenical formulation |
ES2039226T3 (es) * | 1986-12-30 | 1993-09-16 | American Cyanamid Company | Procedimiento para preparar composiciones que contienen policarbofil. |
GB8707421D0 (en) * | 1987-03-27 | 1987-04-29 | Wellcome Found | Pharmaceutical formulations |
GB8707416D0 (en) * | 1987-03-27 | 1987-04-29 | Wellcome Found | Pharmaceutical formulations |
US4789547A (en) * | 1987-06-17 | 1988-12-06 | Warner-Lambert Company | Transdermal matrix system |
US4904477A (en) * | 1987-07-08 | 1990-02-27 | American Home Products Corporation | Spray dried ibuprofen compositions |
US4927639A (en) * | 1989-02-02 | 1990-05-22 | Warner-Lambert Company | Modified release gemfibrozil composition |
US5133974A (en) * | 1989-05-05 | 1992-07-28 | Kv Pharmaceutical Company | Extended release pharmaceutical formulations |
US5122384A (en) * | 1989-05-05 | 1992-06-16 | Kv Pharmaceutical Company | Oral once-per-day organic nitrate formulation which does not induce tolerance |
DE3937455A1 (de) * | 1989-11-10 | 1991-05-16 | Nordmark Arzneimittel Gmbh | Antacidatabletten |
EP0462066A1 (en) * | 1990-06-15 | 1991-12-18 | Warner-Lambert Company | Amorphous gemfibrozil |
US5629016A (en) * | 1991-01-30 | 1997-05-13 | Glaxo Wellcome Inc. | Water-dispersible tablets |
EP0522128B1 (en) * | 1991-01-30 | 1996-01-17 | The Wellcome Foundation Limited | Water-dispersible tablets |
DE4317172A1 (de) * | 1993-05-22 | 1995-01-05 | Rhone Poulenc Rorer Gmbh | Geschmacksneutrale und schnellfreisetzende Buflomedil-Hydrochlorid-Arzneiform und Herstellungsverfahren desselben |
US5698226A (en) * | 1993-07-13 | 1997-12-16 | Glaxo Wellcome Inc. | Water-dispersible tablets |
ES2082723B1 (es) * | 1994-07-20 | 1996-10-01 | Lilly Sa | Formulacion farmaceutica de fluoxetina en forma dispersable. |
US5674529A (en) * | 1995-06-06 | 1997-10-07 | Church & Dwight Co., Inc. | Alkalinizing potassium salt controlled release preparations |
CA2235707A1 (en) * | 1995-11-14 | 1997-05-22 | Knoll Pharmaceutical Company | Stabilized thyroid hormone preparations and methods of making same |
US5773031A (en) * | 1996-02-27 | 1998-06-30 | L. Perrigo Company | Acetaminophen sustained-release formulation |
ES2188928T3 (es) * | 1996-04-26 | 2003-07-01 | Shionogi & Co | Pastilla de liberador-rapido s1452. |
FR2766089B1 (fr) * | 1997-07-21 | 2000-06-02 | Prographarm Lab | Comprime multiparticulaire perfectionne a delitement rapide |
HU221435B (en) * | 1998-02-20 | 2002-10-28 | Egyt Gyogyszervegyeszeti Gyar | Pellet-based pharmaceutical composition of controlled release with high content of potassium-chloride, and process for it's production |
FR2781793B1 (fr) | 1998-08-03 | 2001-07-20 | Prographarm Lab | Procede de fabrication de granules de gabapentine enrobes |
US6723342B1 (en) | 1999-02-08 | 2004-04-20 | Fmc Corporation | Edible coating composition |
US6432448B1 (en) | 1999-02-08 | 2002-08-13 | Fmc Corporation | Edible coating composition |
US6500462B1 (en) * | 1999-10-29 | 2002-12-31 | Fmc Corporation | Edible MCC/PGA coating composition |
US6399101B1 (en) | 2000-03-30 | 2002-06-04 | Mova Pharmaceutical Corp. | Stable thyroid hormone preparations and method of making same |
DK1276470T3 (da) | 2000-04-20 | 2007-06-18 | Novartis Ag | Smagskaskerende overtrækssammensætning |
US6932861B2 (en) * | 2000-11-28 | 2005-08-23 | Fmc Corporation | Edible PGA coating composition |
IL155959A0 (en) | 2000-11-28 | 2003-12-23 | Fmc Corp | Edible pga (propylene glycol alginate) coating composition |
US20030032675A1 (en) * | 2001-02-15 | 2003-02-13 | Franz G. Andrew | Manufacture of thyroid hormone tablets having consistent active moiety amounts |
US6555581B1 (en) | 2001-02-15 | 2003-04-29 | Jones Pharma, Inc. | Levothyroxine compositions and methods |
US20030224047A1 (en) * | 2001-02-15 | 2003-12-04 | Franz G. Andrew | Levothyroxine compositions and methods |
KR20040100835A (ko) * | 2001-02-15 | 2004-12-02 | 킹 파머슈티칼스 리서치 앤드 디벨로프먼트 아이엔씨 | 안정된 제약및 갑상선 내분비 호르몬 구성물 및 그제조방법 |
US20030198667A1 (en) * | 2001-08-10 | 2003-10-23 | Franz Andrew G. | Methods of producing dispersible pharmaceutical compositions |
US20030198671A1 (en) * | 2001-08-10 | 2003-10-23 | Franz G. Andrew | Levothyroxine compositions having unique plasma AUC properties |
US20030180353A1 (en) * | 2001-08-10 | 2003-09-25 | Franz G. Andrew | Stabilized pharmaceutical compositions |
US20030190349A1 (en) * | 2001-08-10 | 2003-10-09 | Franz G. Andrew | Methods of stabilizing pharmaceutical compositions |
US20030195253A1 (en) * | 2001-08-14 | 2003-10-16 | Franz G. Andrew | Unadsorbed levothyroxine pharmaceutical compositions, methods of making and methods of administration |
US7101569B2 (en) | 2001-08-14 | 2006-09-05 | Franz G Andrew | Methods of administering levothyroxine pharmaceutical compositions |
US20030198672A1 (en) * | 2001-08-14 | 2003-10-23 | Franz G. Andrew | Levothyroxine compositions having unique triidothyronine plasma AUC properties |
US20030203967A1 (en) * | 2001-08-14 | 2003-10-30 | Franz G. Andrew | Levothyroxine compositions having unique Tmax properties |
US20030199587A1 (en) * | 2001-08-14 | 2003-10-23 | Franz G. Andrew | Levothyroxine compositions having unique Cmax properties |
US20030199586A1 (en) * | 2001-08-14 | 2003-10-23 | Franz G. Andrew | Unique levothyroxine aqueous materials |
US20030175337A1 (en) * | 2001-10-29 | 2003-09-18 | Franz G. Andrew | Levothyroxine compositions having unique triiodothyronine Tmax properties |
US6645526B2 (en) * | 2001-11-13 | 2003-11-11 | Mylan Pharmaceuticals, Inc. | Storage stable thyroxine active drug formulations and methods for their production |
US20030099699A1 (en) | 2001-11-13 | 2003-05-29 | Hanshew Dwight D. | Storage stable thyroxine active drug formulations and methods for their production |
CN1638803A (zh) * | 2002-03-06 | 2005-07-13 | 协和发酵工业株式会社 | 口腔内速崩解性片剂 |
US20040029959A1 (en) * | 2002-08-08 | 2004-02-12 | John Devane | Isosorbide mononitrate compositions and methods of their use |
US7632521B2 (en) * | 2003-07-15 | 2009-12-15 | Eurand, Inc. | Controlled release potassium chloride tablets |
EP2026768B1 (en) * | 2006-06-01 | 2018-02-28 | Dexcel Pharma Technologies Ltd. | Multiple unit pharmaceutical formulation |
EP2101739A2 (en) * | 2006-12-21 | 2009-09-23 | Mallinckrodt Inc. | Composition of and method for preparing orally disintegrating tablets containing a high dose of pharmaceutically active ingredients |
WO2008079342A2 (en) * | 2006-12-21 | 2008-07-03 | Mallinckrodt Inc. | Composition of and method for preparing orally disintegrating tablets |
CN101380474B (zh) * | 2007-09-06 | 2012-07-25 | 北京大学 | 用于口服制剂的pH敏感性固体药物组合物及制备方法 |
CA2902911C (en) | 2014-10-31 | 2017-06-27 | Purdue Pharma | Methods and compositions particularly for treatment of attention deficit disorder |
EP3288556A4 (en) | 2015-04-29 | 2018-09-19 | Dexcel Pharma Technologies Ltd. | Orally disintegrating compositions |
US10076494B2 (en) | 2016-06-16 | 2018-09-18 | Dexcel Pharma Technologies Ltd. | Stable orally disintegrating pharmaceutical compositions |
US10722473B2 (en) | 2018-11-19 | 2020-07-28 | Purdue Pharma L.P. | Methods and compositions particularly for treatment of attention deficit disorder |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE2200778B2 (de) * | 1971-01-13 | 1974-04-18 | Sandoz Ag, Basel (Schweiz) | Verwendung von hochmolekularem, unlöslichem, quervernetztem Polyvinylpyrrolidon als Sprengmittel in festen Arzneiformen |
BE785702A (fr) * | 1971-07-14 | 1972-10-16 | Roehm Gmbh | Produits de revetement de formes medicamenteuses et leur utilisation |
GB1540754A (en) * | 1976-03-10 | 1979-02-14 | Wellcome Found | Tablet formulation |
JPS5535031A (en) * | 1978-09-04 | 1980-03-11 | Shin Etsu Chem Co Ltd | Enteric coating composition |
US4505896A (en) * | 1979-04-19 | 1985-03-19 | Elorac, Ltd. | Method of treating acne vulgaris and composition |
CH642809B (fr) * | 1980-11-07 | Longines Montres Comp D | Montre avec un mecanisme de quantieme perpetuel. | |
ATE13486T1 (de) * | 1980-11-12 | 1985-06-15 | Ciba Geigy Ag | Schnellzerfallende arzneimittel-presslinge. |
EP0052075A1 (de) * | 1980-11-12 | 1982-05-19 | Ciba-Geigy Ag | Körnige Arzneimittel-Retardform |
IT1168014B (it) * | 1981-08-05 | 1987-05-20 | Erba Farmitalia | Forme farmaceutiche a cessione protratta |
-
1984
- 1984-03-23 CH CH1465/84A patent/CH658188A5/de not_active IP Right Cessation
-
1985
- 1985-03-13 US US06/711,137 patent/US4666703A/en not_active Expired - Fee Related
- 1985-03-15 GB GB08506758A patent/GB2157170B/en not_active Expired
- 1985-03-20 SE SE8501370A patent/SE8501370L/xx unknown
- 1985-03-20 DE DE19853510129 patent/DE3510129A1/de not_active Withdrawn
- 1985-03-20 LU LU85817A patent/LU85817A1/de unknown
- 1985-03-20 IL IL74666A patent/IL74666A/xx unknown
- 1985-03-20 FI FI851114A patent/FI82187C/fi not_active IP Right Cessation
- 1985-03-21 FR FR858504193A patent/FR2561524B1/fr not_active Expired - Lifetime
- 1985-03-21 PT PT80147A patent/PT80147B/pt not_active IP Right Cessation
- 1985-03-21 IT IT47844/85A patent/IT1182723B/it active
- 1985-03-21 CA CA000477095A patent/CA1239348A/en not_active Expired
- 1985-03-21 GR GR850717A patent/GR850717B/el unknown
- 1985-03-22 AT AT0086885A patent/AT394310B/de not_active IP Right Cessation
- 1985-03-22 JP JP60055710A patent/JPS60209518A/ja active Granted
- 1985-03-22 NZ NZ211537A patent/NZ211537A/en unknown
- 1985-03-22 AU AU40287/85A patent/AU579355B2/en not_active Ceased
- 1985-03-22 NL NL8500856A patent/NL8500856A/nl not_active Application Discontinuation
- 1985-03-22 ES ES541513A patent/ES8702786A1/es not_active Expired
- 1985-03-22 BE BE0/214685A patent/BE901994A/fr not_active IP Right Cessation
- 1985-03-22 IE IE744/85A patent/IE57954B1/en not_active IP Right Cessation
- 1985-03-22 DK DK130685A patent/DK162375C/da active
- 1985-03-22 NO NO851170A patent/NO170125C/no unknown
- 1985-03-22 ZA ZA852160A patent/ZA852160B/xx unknown
-
1990
- 1990-06-30 SG SG468/90A patent/SG46890G/en unknown
- 1990-09-13 HK HK730/90A patent/HK73090A/xx unknown
Cited By (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES2059260A1 (es) * | 1992-10-06 | 1994-11-01 | Espanola Prod Quimicos | Procedimiento de preparacion de comprimidos conteniendo diclofenaco; dispersables en agua. |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FD1A | Patent lapsed |
Effective date: 19970519 |