IT1182723B - Tavoletta di sostanza attiva farmaceutica che si disgrega rapidamente stabili al magazzinaggio - Google Patents

Tavoletta di sostanza attiva farmaceutica che si disgrega rapidamente stabili al magazzinaggio

Info

Publication number
IT1182723B
IT1182723B IT47844/85A IT4784485A IT1182723B IT 1182723 B IT1182723 B IT 1182723B IT 47844/85 A IT47844/85 A IT 47844/85A IT 4784485 A IT4784485 A IT 4784485A IT 1182723 B IT1182723 B IT 1182723B
Authority
IT
Italy
Prior art keywords
disregrates
tablet
storage
active substance
pharmaceutical active
Prior art date
Application number
IT47844/85A
Other languages
English (en)
Other versions
IT8547844A1 (it
IT8547844A0 (it
Inventor
Dr Helmut Kopf
Original Assignee
Ciba Geigy Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Ciba Geigy Ag filed Critical Ciba Geigy Ag
Publication of IT8547844A0 publication Critical patent/IT8547844A0/it
Publication of IT8547844A1 publication Critical patent/IT8547844A1/it
Application granted granted Critical
Publication of IT1182723B publication Critical patent/IT1182723B/it

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
    • A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
    • A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
    • A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
    • A61K9/5005—Wall or coating material
    • A61K9/5021—Organic macromolecular compounds
    • A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
    • A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
    • A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose

Landscapes

  • Health & Medical Sciences (AREA)
  • Epidemiology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
IT47844/85A 1984-03-23 1985-03-21 Tavoletta di sostanza attiva farmaceutica che si disgrega rapidamente stabili al magazzinaggio IT1182723B (it)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH1465/84A CH658188A5 (de) 1984-03-23 1984-03-23 Lagerstabile schnellzerfallende pharmazeutische presslinge.

Publications (3)

Publication Number Publication Date
IT8547844A0 IT8547844A0 (it) 1985-03-21
IT8547844A1 IT8547844A1 (it) 1986-09-21
IT1182723B true IT1182723B (it) 1987-10-05

Family

ID=4211107

Family Applications (1)

Application Number Title Priority Date Filing Date
IT47844/85A IT1182723B (it) 1984-03-23 1985-03-21 Tavoletta di sostanza attiva farmaceutica che si disgrega rapidamente stabili al magazzinaggio

Country Status (26)

Country Link
US (1) US4666703A (it)
JP (1) JPS60209518A (it)
AT (1) AT394310B (it)
AU (1) AU579355B2 (it)
BE (1) BE901994A (it)
CA (1) CA1239348A (it)
CH (1) CH658188A5 (it)
DE (1) DE3510129A1 (it)
DK (1) DK162375C (it)
ES (1) ES8702786A1 (it)
FI (1) FI82187C (it)
FR (1) FR2561524B1 (it)
GB (1) GB2157170B (it)
GR (1) GR850717B (it)
HK (1) HK73090A (it)
IE (1) IE57954B1 (it)
IL (1) IL74666A (it)
IT (1) IT1182723B (it)
LU (1) LU85817A1 (it)
NL (1) NL8500856A (it)
NO (1) NO170125C (it)
NZ (1) NZ211537A (it)
PT (1) PT80147B (it)
SE (1) SE8501370L (it)
SG (1) SG46890G (it)
ZA (1) ZA852160B (it)

Families Citing this family (68)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AT350735B (de) * 1976-08-06 1979-06-11 Hoffmann La Roche Verfahren zur herstellung von neuen ribo- furanosyl-imidazolderivaten
CA1270765A (en) * 1985-02-19 1990-06-26 Charles Hsiao Controlled release potassium chloride
IE59066B1 (en) * 1985-02-19 1993-12-15 Key Pharma Controlled release potassium chloride
GB8519310D0 (en) * 1985-07-31 1985-09-04 Zyma Sa Granular active substances
US4971791A (en) * 1985-08-26 1990-11-20 The Procter & Gamble Company Taste masking compositions
GB8521494D0 (en) * 1985-08-29 1985-10-02 Zyma Sa Controlled release tablet
US5624683A (en) * 1986-08-06 1997-04-29 Eisai Co., Ltd. Sustained-release multi-granule tablet
IT1197316B (it) * 1986-10-01 1988-11-30 Proter Spa Formulazione galenica ad uso orale di derivati della reina a lento rilascio per impiego terapeutico
US4800087A (en) * 1986-11-24 1989-01-24 Mehta Atul M Taste-masked pharmaceutical compositions
GB8628359D0 (en) * 1986-11-27 1986-12-31 Zyma Sa Galenical formulation
ES2039226T3 (es) * 1986-12-30 1993-09-16 American Cyanamid Company Procedimiento para preparar composiciones que contienen policarbofil.
GB8707416D0 (en) * 1987-03-27 1987-04-29 Wellcome Found Pharmaceutical formulations
GB8707421D0 (en) * 1987-03-27 1987-04-29 Wellcome Found Pharmaceutical formulations
US4789547A (en) * 1987-06-17 1988-12-06 Warner-Lambert Company Transdermal matrix system
US4904477A (en) * 1987-07-08 1990-02-27 American Home Products Corporation Spray dried ibuprofen compositions
US4927639A (en) * 1989-02-02 1990-05-22 Warner-Lambert Company Modified release gemfibrozil composition
US5122384A (en) * 1989-05-05 1992-06-16 Kv Pharmaceutical Company Oral once-per-day organic nitrate formulation which does not induce tolerance
US5133974A (en) * 1989-05-05 1992-07-28 Kv Pharmaceutical Company Extended release pharmaceutical formulations
DE3937455A1 (de) * 1989-11-10 1991-05-16 Nordmark Arzneimittel Gmbh Antacidatabletten
EP0462066A1 (en) * 1990-06-15 1991-12-18 Warner-Lambert Company Amorphous gemfibrozil
US5629016A (en) * 1991-01-30 1997-05-13 Glaxo Wellcome Inc. Water-dispersible tablets
IL100796A (en) * 1991-01-30 1998-09-24 Wellcome Found Water-dispersed tablets containing acyclovir or lemotrigin
ES2059260B1 (es) * 1992-10-06 1995-04-16 Espanola Prod Quimicos Procedimiento de preparacion de comprimidos conteniendo diclofenaco; dispersables en agua.
DE4317172A1 (de) * 1993-05-22 1995-01-05 Rhone Poulenc Rorer Gmbh Geschmacksneutrale und schnellfreisetzende Buflomedil-Hydrochlorid-Arzneiform und Herstellungsverfahren desselben
US5698226A (en) * 1993-07-13 1997-12-16 Glaxo Wellcome Inc. Water-dispersible tablets
ES2082723B1 (es) * 1994-07-20 1996-10-01 Lilly Sa Formulacion farmaceutica de fluoxetina en forma dispersable.
US5674529A (en) * 1995-06-06 1997-10-07 Church & Dwight Co., Inc. Alkalinizing potassium salt controlled release preparations
WO1997017951A1 (en) * 1995-11-14 1997-05-22 Knoll Pharmaceutical Company Stabilized thyroid hormone preparations and methods of making same
US5773031A (en) * 1996-02-27 1998-06-30 L. Perrigo Company Acetaminophen sustained-release formulation
DE69717810T2 (de) * 1996-04-26 2003-09-18 Shionogi & Co S1452-tabletten mit schneller freisetzung
FR2766089B1 (fr) * 1997-07-21 2000-06-02 Prographarm Lab Comprime multiparticulaire perfectionne a delitement rapide
HU221435B (en) * 1998-02-20 2002-10-28 Egyt Gyogyszervegyeszeti Gyar Pellet-based pharmaceutical composition of controlled release with high content of potassium-chloride, and process for it's production
FR2781793B1 (fr) 1998-08-03 2001-07-20 Prographarm Lab Procede de fabrication de granules de gabapentine enrobes
US6723342B1 (en) 1999-02-08 2004-04-20 Fmc Corporation Edible coating composition
US6432448B1 (en) 1999-02-08 2002-08-13 Fmc Corporation Edible coating composition
US6500462B1 (en) * 1999-10-29 2002-12-31 Fmc Corporation Edible MCC/PGA coating composition
US6399101B1 (en) 2000-03-30 2002-06-04 Mova Pharmaceutical Corp. Stable thyroid hormone preparations and method of making same
EP1276470B1 (en) 2000-04-20 2007-05-02 Novartis AG Taste masking coating composition
US6932861B2 (en) 2000-11-28 2005-08-23 Fmc Corporation Edible PGA coating composition
IL155959A0 (en) 2000-11-28 2003-12-23 Fmc Corp Edible pga (propylene glycol alginate) coating composition
US20030224047A1 (en) * 2001-02-15 2003-12-04 Franz G. Andrew Levothyroxine compositions and methods
JP2004525109A (ja) * 2001-02-15 2004-08-19 キング・ファーマシューティカルズ・インコーポレイティッド 安定化された甲状腺ホルモン医薬組成物、及びその製法
US6555581B1 (en) 2001-02-15 2003-04-29 Jones Pharma, Inc. Levothyroxine compositions and methods
US20030032675A1 (en) * 2001-02-15 2003-02-13 Franz G. Andrew Manufacture of thyroid hormone tablets having consistent active moiety amounts
US20030190349A1 (en) * 2001-08-10 2003-10-09 Franz G. Andrew Methods of stabilizing pharmaceutical compositions
US20030198671A1 (en) * 2001-08-10 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique plasma AUC properties
US20030180353A1 (en) * 2001-08-10 2003-09-25 Franz G. Andrew Stabilized pharmaceutical compositions
US20030198667A1 (en) * 2001-08-10 2003-10-23 Franz Andrew G. Methods of producing dispersible pharmaceutical compositions
US20030203967A1 (en) * 2001-08-14 2003-10-30 Franz G. Andrew Levothyroxine compositions having unique Tmax properties
US20030199587A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique Cmax properties
US20030195253A1 (en) * 2001-08-14 2003-10-16 Franz G. Andrew Unadsorbed levothyroxine pharmaceutical compositions, methods of making and methods of administration
US20030199586A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Unique levothyroxine aqueous materials
US20030198672A1 (en) * 2001-08-14 2003-10-23 Franz G. Andrew Levothyroxine compositions having unique triidothyronine plasma AUC properties
US7101569B2 (en) 2001-08-14 2006-09-05 Franz G Andrew Methods of administering levothyroxine pharmaceutical compositions
US20030175337A1 (en) * 2001-10-29 2003-09-18 Franz G. Andrew Levothyroxine compositions having unique triiodothyronine Tmax properties
US20030099699A1 (en) 2001-11-13 2003-05-29 Hanshew Dwight D. Storage stable thyroxine active drug formulations and methods for their production
US6645526B2 (en) * 2001-11-13 2003-11-11 Mylan Pharmaceuticals, Inc. Storage stable thyroxine active drug formulations and methods for their production
EP1488811A1 (en) * 2002-03-06 2004-12-22 Kyowa Hakko Kogyo Co., Ltd. Tablets quickly disintegrating in oral cavity
US20040029959A1 (en) * 2002-08-08 2004-02-12 John Devane Isosorbide mononitrate compositions and methods of their use
US7632521B2 (en) * 2003-07-15 2009-12-15 Eurand, Inc. Controlled release potassium chloride tablets
WO2007138606A2 (en) * 2006-06-01 2007-12-06 Dexcel Pharma Technologies Ltd. Multiple unit pharmaceutical formulation
EP2101738A2 (en) * 2006-12-21 2009-09-23 Mallinckrodt Inc. Composition of and method for preparing orally disintegrating tablets
AU2007338751A1 (en) * 2006-12-21 2008-07-03 Mallinckrodt Inc. Composition of and method for preparing orally disintegrating tablets containing a high dose of pharmaceutically active ingredients
CN101380474B (zh) * 2007-09-06 2012-07-25 北京大学 用于口服制剂的pH敏感性固体药物组合物及制备方法
CA2936748C (en) 2014-10-31 2017-08-08 Purdue Pharma Methods and compositions particularly for treatment of attention deficit disorder
EP3288556A4 (en) 2015-04-29 2018-09-19 Dexcel Pharma Technologies Ltd. Orally disintegrating compositions
US10076494B2 (en) 2016-06-16 2018-09-18 Dexcel Pharma Technologies Ltd. Stable orally disintegrating pharmaceutical compositions
US10722473B2 (en) 2018-11-19 2020-07-28 Purdue Pharma L.P. Methods and compositions particularly for treatment of attention deficit disorder

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2200778B2 (de) * 1971-01-13 1974-04-18 Sandoz Ag, Basel (Schweiz) Verwendung von hochmolekularem, unlöslichem, quervernetztem Polyvinylpyrrolidon als Sprengmittel in festen Arzneiformen
BE785702A (fr) * 1971-07-14 1972-10-16 Roehm Gmbh Produits de revetement de formes medicamenteuses et leur utilisation
GB1540754A (en) * 1976-03-10 1979-02-14 Wellcome Found Tablet formulation
JPS5535031A (en) * 1978-09-04 1980-03-11 Shin Etsu Chem Co Ltd Enteric coating composition
US4505896A (en) * 1979-04-19 1985-03-19 Elorac, Ltd. Method of treating acne vulgaris and composition
CH642809B (fr) * 1980-11-07 Longines Montres Comp D Montre avec un mecanisme de quantieme perpetuel.
EP0052076B1 (de) * 1980-11-12 1985-05-29 Ciba-Geigy Ag Schnellzerfallende Arzneimittel-Presslinge
EP0052075A1 (de) * 1980-11-12 1982-05-19 Ciba-Geigy Ag Körnige Arzneimittel-Retardform
IT1168014B (it) * 1981-08-05 1987-05-20 Erba Farmitalia Forme farmaceutiche a cessione protratta

Also Published As

Publication number Publication date
IT8547844A1 (it) 1986-09-21
FR2561524A1 (fr) 1985-09-27
LU85817A1 (de) 1985-12-12
GB2157170A (en) 1985-10-23
AU4028785A (en) 1985-09-26
ES541513A0 (es) 1987-01-16
IE57954B1 (en) 1993-05-19
FI851114A0 (fi) 1985-03-20
DK162375C (da) 1992-03-09
ES8702786A1 (es) 1987-01-16
US4666703A (en) 1987-05-19
ZA852160B (en) 1985-11-27
FI82187B (fi) 1990-10-31
IT8547844A0 (it) 1985-03-21
SE8501370L (sv) 1985-09-24
IE850744L (en) 1985-09-23
CH658188A5 (de) 1986-10-31
NZ211537A (en) 1988-03-30
DK130685D0 (da) 1985-03-22
AU579355B2 (en) 1988-11-24
NL8500856A (nl) 1985-10-16
SG46890G (en) 1990-08-17
JPH0574568B2 (it) 1993-10-18
CA1239348A (en) 1988-07-19
NO851170L (no) 1985-09-24
IL74666A (en) 1988-11-30
AT394310B (de) 1992-03-10
GB2157170B (en) 1988-01-20
BE901994A (fr) 1985-09-23
FI851114L (fi) 1985-09-24
HK73090A (en) 1990-09-21
NO170125B (no) 1992-06-09
SE8501370D0 (sv) 1985-03-20
GR850717B (it) 1985-07-19
DE3510129A1 (de) 1985-10-03
GB8506758D0 (en) 1985-04-17
IL74666A0 (en) 1985-06-30
DK130685A (da) 1985-09-24
PT80147B (pt) 1987-10-20
FI82187C (fi) 1991-02-11
NO170125C (no) 1992-09-16
FR2561524B1 (fr) 1990-01-12
JPS60209518A (ja) 1985-10-22
PT80147A (en) 1985-04-01
ATA86885A (de) 1991-09-15
DK162375B (da) 1991-10-21

Similar Documents

Publication Publication Date Title
IT1182723B (it) Tavoletta di sostanza attiva farmaceutica che si disgrega rapidamente stabili al magazzinaggio
IT1145285B (it) Compressa divisibile con erogazione controllata e ritardata di sostanza attiva
FR2608427B1 (fr) Hydrosols de substances pharmacologiquement actives et compositions pharmaceutiques les contenant
IT1116877B (it) Forma farmaceutica per erogazione ritardata di sostanze medicinali con guscio poroso insolubile e procedimento di idruzione
IT8267184A0 (it) Bendaggio per la somministrazione di medicamenti
IL60326A0 (en) Pharmaceutical compositions for parenteral administration of fatsolbule active substances
GB8502974D0 (en) Sustained release of active substance
IT8449164A0 (it) Ti sucralfat e procedimento per la composizioni farmaceutiche contenenloro stabilizzazione
IT8721253A0 (it) Composizioni farmaceutiche e cosmetiche contenenti complessi di flavonolignani con fosfolipidi.
IT8468241A0 (it) Derivati del triptofano farmaceuti camente attivi e composizioni farmaceutiche che li contengono
DK257383A (da) Lagerstabil tablet indeholdende hydrolysefoelsomt aktivt stof
FI831998A0 (fi) Foerfarande foer framstaellning av farmaceutiskt aktiva pyrazinonderivat
IT1158048B (it) Preparato farmaceutico equilibrato idrodinamicamente dotato di cessione protratta della sostanza attiva
IT1156745B (it) Farmaci contenenti composti sterolici 15-ossigenati e procedimento per impedire la biosintesi di acido mevalonico
IT1182061B (it) Derivati di amminofenolo, procedimento per prepararli e composizione farmaceutica che li contiene
IT8149623A0 (it) Derivati encefalinici dotati di attivita' analgesica e composizioni farmaceutiche che li contengono
IT1188985B (it) Fenossiammine eterocicliche sostituite procedimento per prepararle e composizioni farmaceutiche che le contengono
IT8747701A0 (it) Composizioni stabili allo stoccaggio di assorbenti uv
PT87550A (pt) Process for the preparation of pyrimidine derivatives and of pharmaceutical compositions containing the same
ITMI911059A1 (it) Acido metiltauroursodesossicolico e suoi derivati terapeuticamente attivi procedimento per la sua preparazione e composizioni farmaceutiche che lo contengono
IL65922A0 (en) Preparation of apovincaminic acid esters,certain novel optically active derivatives thereof and pharmaceutical compositions containing them
IT8267345A0 (it) Composto e composizione farmaceutica per accelerare la cicatrizzazione di ferite
IT1186722B (it) Composizione farmaceutica per applicazioni topiche per la cessione graudale di iodio
DE178212T1 (de) Pharmazeutischer wirkstofftraeger in form eines wasserfreien gels.
IT1205360B (it) Derivati di dioloroanilina,procedimento per prepararli e composizioni farmaceutiche che li contengono

Legal Events

Date Code Title Description
TA Fee payment date (situation as of event date), data collected since 19931001

Effective date: 19940322