ES2059260A1 - Procedimiento de preparacion de comprimidos conteniendo diclofenaco; dispersables en agua. - Google Patents
Procedimiento de preparacion de comprimidos conteniendo diclofenaco; dispersables en agua.Info
- Publication number
- ES2059260A1 ES2059260A1 ES09201978A ES9201978A ES2059260A1 ES 2059260 A1 ES2059260 A1 ES 2059260A1 ES 09201978 A ES09201978 A ES 09201978A ES 9201978 A ES9201978 A ES 9201978A ES 2059260 A1 ES2059260 A1 ES 2059260A1
- Authority
- ES
- Spain
- Prior art keywords
- tablets containing
- prepare water
- containing diclofenac
- diclofenac
- disintegrant
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Granted
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/185—Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
- A61K31/19—Carboxylic acids, e.g. valproic acid
- A61K31/195—Carboxylic acids, e.g. valproic acid having an amino group
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Abstract
SE DESCRIBE UN NUEVO PROCEDIMIENTO DE PREPARACION DE UNA NUEVA FORMULACION DE COMPRIMIDOS DISPERSABLES DE DICLOFENACO, CARACTERIZADO PORQUE SE COMPRIME UNA MEZCLA CONSTITUIDA POR UN GRANULADO QUE, JUNTAMENTE CON DICLOFENACO MICRONIZADO, COMO PRINCIPIO ACTIVO, Y OTROS EXCIPIENTES, CONTIENE UN LUBRICANTE HIDROFILO Y UN DISGREGANTE, Y UN SOLIDO PULVERULENTO QUE, JUNTAMENTE CON OTROS EXCIPIENTES, INCORPORA TAMBIEN UN LUBRICANTE HIDROFILO Y UN DISGREGANTE. LOS LUBRICANTES HIDROFILOS SE ENCUENTRAN EN UNA PROPORCION ENTRE EL 2,5 Y EL 5% Y LOS DISGREGANTES ENTRE EL 13 Y EL 17% DEL PESO DE LA FORMULACION.
Priority Applications (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9201978A ES2059260B1 (es) | 1992-10-06 | 1992-10-06 | Procedimiento de preparacion de comprimidos conteniendo diclofenaco; dispersables en agua. |
DE69329591T DE69329591D1 (de) | 1992-10-06 | 1993-09-10 | Verfahren zur Herstellung wasserdispergierbarer Diclofenac enthaltender Tabletten |
EP19930500129 EP0599767B1 (en) | 1992-10-06 | 1993-09-10 | Process to prepare water-dispersable tablets containing diclofenac |
PT93500129T PT599767E (pt) | 1992-10-06 | 1993-09-10 | Processo de preparacao de pastilhas dispersaveis em agua contendo diclofenac |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
ES9201978A ES2059260B1 (es) | 1992-10-06 | 1992-10-06 | Procedimiento de preparacion de comprimidos conteniendo diclofenaco; dispersables en agua. |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2059260A1 true ES2059260A1 (es) | 1994-11-01 |
ES2059260B1 ES2059260B1 (es) | 1995-04-16 |
Family
ID=8278320
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES9201978A Expired - Fee Related ES2059260B1 (es) | 1992-10-06 | 1992-10-06 | Procedimiento de preparacion de comprimidos conteniendo diclofenaco; dispersables en agua. |
Country Status (4)
Country | Link |
---|---|
EP (1) | EP0599767B1 (es) |
DE (1) | DE69329591D1 (es) |
ES (1) | ES2059260B1 (es) |
PT (1) | PT599767E (es) |
Families Citing this family (7)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0890359B1 (en) * | 1996-02-29 | 2002-05-02 | Fujisawa Pharmaceutical Co., Ltd. | Tablets containing beta-lactam antibiotic and process for producing the same |
US6312724B1 (en) | 1997-04-04 | 2001-11-06 | Isa Odidi | Sustained release pharmaceutical matrix tablet of pharmaceutically acceptable salts of diclofenac and process for preparation thereof |
US6509040B1 (en) | 2001-06-22 | 2003-01-21 | R.P. Scherer Corporation | Fast dispersing dosage forms essentially free of mammalian gelatin |
ES2602730T3 (es) | 2003-09-24 | 2017-02-22 | Novartis Consumer Health S.A. | Comprimidos de diclofenaco revestidos |
WO2013052019A1 (en) | 2011-08-19 | 2013-04-11 | Mahmut Bilgic | Production method for effervescent formulations comprising diclofenac |
US11957792B2 (en) | 2012-04-19 | 2024-04-16 | Glatt Ag | Taste-masked pharmaceutical compositions containing diclofenac |
CN111603451A (zh) * | 2020-06-23 | 2020-09-01 | 瑞阳制药有限公司 | 双氯灭痛分散片的制备方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES8702786A1 (es) * | 1984-03-23 | 1987-01-16 | Ciba Geigy Ag | Procedimiento para la obtencion de comprimidos de sustancia activa farmaceutica, de rapida desintegracion |
EP0365480A1 (en) * | 1988-10-18 | 1990-04-25 | Ciba-Geigy Ag | Dispersible formulation |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1492019A1 (de) * | 1963-06-20 | 1969-02-20 | Ministerul Ind Petrolului Si C | Zuschlag fuer Arzneimitteltabletten und Verfahren zu ihrer Gewinnung |
FR2525474A1 (fr) * | 1982-04-26 | 1983-10-28 | Roussel Uclaf | Nouvelle forme pharmaceutique orale de clometacine |
GB8521350D0 (en) * | 1985-08-28 | 1985-10-02 | Euro Celtique Sa | Analgesic composition |
CA2019324C (en) * | 1989-07-10 | 1996-08-20 | Robert L. Jerzewski | Fosinopril tablet formulations |
SE9003904D0 (sv) * | 1990-12-07 | 1990-12-07 | Astra Ab | Method for the manufacture of a pharmaceutical dosage form |
-
1992
- 1992-10-06 ES ES9201978A patent/ES2059260B1/es not_active Expired - Fee Related
-
1993
- 1993-09-10 EP EP19930500129 patent/EP0599767B1/en not_active Expired - Lifetime
- 1993-09-10 PT PT93500129T patent/PT599767E/pt unknown
- 1993-09-10 DE DE69329591T patent/DE69329591D1/de not_active Expired - Lifetime
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ES8702786A1 (es) * | 1984-03-23 | 1987-01-16 | Ciba Geigy Ag | Procedimiento para la obtencion de comprimidos de sustancia activa farmaceutica, de rapida desintegracion |
EP0365480A1 (en) * | 1988-10-18 | 1990-04-25 | Ciba-Geigy Ag | Dispersible formulation |
Also Published As
Publication number | Publication date |
---|---|
DE69329591D1 (de) | 2000-11-30 |
EP0599767A1 (en) | 1994-06-01 |
PT599767E (pt) | 2001-04-30 |
EP0599767B1 (en) | 2000-10-25 |
ES2059260B1 (es) | 1995-04-16 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
GC2A | Exploitation certificate registered application with search report |
Effective date: 19981214 |
|
FD2A | Announcement of lapse in spain |
Effective date: 20141120 |