ES8607252A1 - Procedimiento para preparar derivados de imidazol - Google Patents

Procedimiento para preparar derivados de imidazol

Info

Publication number
ES8607252A1
ES8607252A1 ES541736A ES541736A ES8607252A1 ES 8607252 A1 ES8607252 A1 ES 8607252A1 ES 541736 A ES541736 A ES 541736A ES 541736 A ES541736 A ES 541736A ES 8607252 A1 ES8607252 A1 ES 8607252A1
Authority
ES
Spain
Prior art keywords
redox indicators
present
imidazole derivatives
redox
indicators
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES541736A
Other languages
English (en)
Other versions
ES541736A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Roche Diagnostics GmbH
Original Assignee
Boehringer Mannheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Mannheim GmbH filed Critical Boehringer Mannheim GmbH
Publication of ES541736A0 publication Critical patent/ES541736A0/es
Publication of ES8607252A1 publication Critical patent/ES8607252A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/04—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D455/00—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/03—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine
    • C07D455/04—Heterocyclic compounds containing quinolizine ring systems, e.g. emetine alkaloids, protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing quinolizine ring systems directly condensed with at least one six-membered carbocyclic ring, e.g. protoberberine; Alkylenedioxy derivatives of dibenzo [a, g] quinolizines, e.g. berberine containing a quinolizine ring system condensed with only one six-membered carbocyclic ring, e.g. julolidine
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2326/00—Chromogens for determinations of oxidoreductase enzymes
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10T—TECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00—Chemistry: analytical and immunological testing
    • Y10T436/20—Oxygen containing
    • Y10T436/206664—Ozone or peroxide

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biotechnology (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Steroid Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Glass Compositions (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Lubricants (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Compositions Of Macromolecular Compounds (AREA)
  • Paints Or Removers (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE IMIDAZOL Y DE SUS SALES, DE FORMULA (I), EN LA QUE R, R1 Y R2 PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE CONDENSACION DE UNA A-DICETONA DE FORMULA R2COCOR CON UN ALDEHIDO DE FORMULA (I), EN PRESENCIA DE AMONIACO EN DISOLUCION ACIDA. TAMBIEN SE PUEDE HACER REACCIONAR UNA A-CETOXIMA CON EL ALDEHIDO INDICADO Y AMONIACO, SEGUIDA DE REDUCCION DEL COMPUESTO FORMADO, O BIEN UNA AMIDINA CON UN BROMURO DE ACILO ADECUADO. ESTOS COMPUESTOS TIENEN APLICACIONES EN QUIMICA ANALITICA COMO INDICADORES REDOX PARA LA DETERMINACION DE PEROXIDO DE HIDROGENO Y PEROXIDASA.
ES541736A 1984-03-31 1985-03-29 Procedimiento para preparar derivados de imidazol Expired ES8607252A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3411997A DE3411997A1 (de) 1984-03-31 1984-03-31 Neue redox-indikatoren

Publications (2)

Publication Number Publication Date
ES541736A0 ES541736A0 (es) 1986-06-01
ES8607252A1 true ES8607252A1 (es) 1986-06-01

Family

ID=6232189

Family Applications (2)

Application Number Title Priority Date Filing Date
ES541736A Expired ES8607252A1 (es) 1984-03-31 1985-03-29 Procedimiento para preparar derivados de imidazol
ES551531A Expired ES8701733A1 (es) 1984-03-31 1986-01-31 Procedimiento para detectar peroxido de hidrogeno o sustancias formadoras de peroxido de hidrogeno

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES551531A Expired ES8701733A1 (es) 1984-03-31 1986-01-31 Procedimiento para detectar peroxido de hidrogeno o sustancias formadoras de peroxido de hidrogeno

Country Status (14)

Country Link
US (1) US4665023A (es)
EP (1) EP0161436B1 (es)
JP (1) JPH0643424B2 (es)
AT (1) ATE29265T1 (es)
AU (1) AU553338B2 (es)
CA (1) CA1259997A (es)
CS (2) CS276976B6 (es)
DE (2) DE3411997A1 (es)
DK (1) DK172240B1 (es)
ES (2) ES8607252A1 (es)
HU (1) HU199429B (es)
IE (1) IE58212B1 (es)
SU (1) SU1496644A3 (es)
ZA (1) ZA852382B (es)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4672029A (en) * 1984-12-06 1987-06-09 Eastman Kodak Company Color-forming couplers and their use in the analytical determination of hydrogen peroxide or other analytes
DE3515586A1 (de) * 1985-04-30 1986-11-06 Boehringer Mannheim Gmbh, 6800 Mannheim Stabilisiertes sarcosinoxidase-praeparat
US4921791A (en) * 1986-06-26 1990-05-01 Konishiroku Photo Industry Co., Ltd. Method for measuring specific component using peroxidase enzyme reaction
JPH0619346B2 (ja) * 1986-11-17 1994-03-16 コニカ株式会社 過酸化水素定量用分析素子
EP0285095B1 (en) * 1987-04-02 1994-11-30 Fuji Photo Film Co., Ltd. Dry type analysis element
US5024935A (en) * 1987-12-18 1991-06-18 Eastman Kodak Company Dye-providing composition, diagnostic test kit and their use in method for ligand determination using peroxidase labeled-receptor
JPH03501681A (ja) * 1988-01-11 1991-04-18 ボーリンガー・マンハイム・コーポレイション 乾燥粉末診断剤及びその適用
JPH0833393B2 (ja) * 1988-03-14 1996-03-29 富士写真フイルム株式会社 乾式分析要素
US5017471A (en) * 1988-08-26 1991-05-21 Epitope, Inc. Reagent for peroxidase detection
US5274095A (en) * 1989-05-31 1993-12-28 Boehringer Mannheim Gmbh Diarylimidazoles
DE3917677A1 (de) * 1989-05-31 1990-12-06 Boehringer Mannheim Gmbh Diarylimidazole
US6395227B1 (en) * 1989-08-28 2002-05-28 Lifescan, Inc. Test strip for measuring analyte concentration over a broad range of sample volume
US5620863A (en) * 1989-08-28 1997-04-15 Lifescan, Inc. Blood glucose strip having reduced side reactions
AU621245B2 (en) * 1989-10-17 1992-03-05 Boehringer Mannheim Gmbh Hydrolase substrates, a process for the preparation thereof and agents containing them
US5633376A (en) * 1990-12-28 1997-05-27 Neurogen Corporation Certain aminomethyl phenylimidazole derivatives; and 4-aryl substituted piperazinyl and piperidinylmethyl phenylimidazole derivatives; a new class of dopamine receptor subtype ligands
US5646280A (en) * 1990-12-28 1997-07-08 Neurogen Corporation Substituted 4-(alkyl, dialkyl) or cycloaklyl)aminomethyl 2-phenylimidazoes: dopamine receptor subtype specific ligands
US5681956A (en) * 1990-12-28 1997-10-28 Neurogen Corporation 4-aryl substituted piperazinylmethyl phenylimidazole derivatives; a new class of dopamine receptor subtype specific ligands
US5712392A (en) * 1990-12-28 1998-01-27 Neurogen Corporation Certain 4-piperidine- and piperazinoalkyl-2-phenyl imidazole derivatives; dopamine receptor subtype specific ligands
US5208326A (en) * 1991-11-08 1993-05-04 Miles Inc. 8-hydroxy-2h-dibenz(b,f)azepin-2-one dyes
US5415809A (en) * 1992-07-15 1995-05-16 Aquarium Pharmaceuticals, Inc. Method for determination of dissolved oxygen in water
US5700826A (en) * 1995-06-07 1997-12-23 Ontogen Corporation 1,2,4,5-tetra substituted imidazoles as modulators of multi-drug resistance
WO1999001128A1 (en) 1997-07-03 1999-01-14 Neurogen Corporation Certain diarylimidazole derivatives; a new class of npy specific ligands
US5840721A (en) * 1997-07-09 1998-11-24 Ontogen Corporation Imidazole derivatives as MDR modulators
US6166205A (en) * 1998-09-02 2000-12-26 Neurogen Corporation 2-Aryl-4-(1-[4-heteroaryl]piperazin-1-yl)methylimidazoles: dopamine . D.sub4 receptor subtype ligands
DE19945828B4 (de) 1999-09-24 2011-06-01 Roche Diagnostics Gmbh Analysenelement und Verfahren zur Bestimmung eines Analyten in Flüssigkeit
JP4189140B2 (ja) * 2001-09-07 2008-12-03 富士フイルム株式会社 乾式免疫分析要素
JP5265257B2 (ja) 2008-06-30 2013-08-14 富士フイルム株式会社 犬ｃｒｐ及び人ｃｒｐを認識する抗体
TWI435871B (zh) 2009-02-04 2014-05-01 Otsuka Pharma Co Ltd 苯基咪唑化合物
JP5292270B2 (ja) 2009-12-21 2013-09-18 富士フイルム株式会社 犬ｃｒｐ測定用乾式分析要素
CN102419366B (zh) * 2011-08-19 2014-03-26 三诺生物传感股份有限公司 一种去除干扰的干化学定量测试试条、谷丙或谷草转氨酶定量测试试条及检测方法
CN102288747B (zh) * 2011-08-19 2013-11-27 长沙三诺生物传感技术股份有限公司 去除干扰的干化学定量测试试条、谷丙或谷草转氨酶定量测试试条及检测方法
JP6618370B2 (ja) * 2015-03-05 2019-12-11 エイブリック株式会社 磁気センサ回路
JP7072778B2 (ja) * 2018-07-04 2022-05-23 国立大学法人京都大学 イミダゾール誘導体の製造方法

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1648840C2 (de) * 1967-10-14 1970-09-17 Boehringer Mannheim GmbH, 6800 Mann" heim-Waldhof Verfahren und diagnostische Mittel zur Bestimmung von Hydroperoxiden und peroxidatisch wirksamen Substanzen
US4278439A (en) * 1979-12-17 1981-07-14 Miles Laboratories, Inc. Sensitizers for peroxidative activity tests
DE3124594A1 (de) * 1981-06-23 1983-01-05 Boehringer Mannheim Gmbh, 6800 Mannheim Mittel und verfahren zum nachweis von wasserstoffperoxid
DE3124590A1 (de) * 1981-06-23 1983-01-27 Boehringer Mannheim Gmbh, 6800 Mannheim Stabilisiertes reagenz zum nachweis von h(pfeil abwaerts)2(pfeil abwaerts)o(pfeil abwaerts)2(pfeil abwaerts)
DE3125667C2 (de) * 1981-06-30 1986-01-23 Boehringer Mannheim Gmbh, 6800 Mannheim Verfahren und Mittel zum Nachweis von Wasserstoffperoxid
US4535165A (en) * 1981-11-23 1985-08-13 Riker Laboratories, Inc. Substituted diazoles and thiazoles
US4472406A (en) * 1982-11-12 1984-09-18 Riker Laboratories, Inc. Antimicrobial 6,7-dihydro-8-(imidazol-1-yl)-5-methyl-1-oxo-1H,5H-benzo [ij]quinolizine-2-carboxylic acids and derivatives
JPS59193352A (ja) * 1983-04-18 1984-11-01 Fuji Photo Film Co Ltd 分析試薬および多層化学分析要素
EP0139584B1 (fr) * 1983-10-17 1988-05-18 Synthelabo Dérivés d'imidazoline, leur préparation et leur application en thérapeutique

Also Published As

Publication number Publication date
DK172240B1 (da) 1998-02-02
JPS60224677A (ja) 1985-11-09
DK142985A (da) 1985-10-01
ES541736A0 (es) 1986-06-01
EP0161436A1 (de) 1985-11-21
DE3411997A1 (de) 1985-10-17
CS276976B6 (en) 1992-11-18
AU553338B2 (en) 1986-07-10
SU1496644A3 (ru) 1989-07-23
ES8701733A1 (es) 1987-01-01
EP0161436B1 (de) 1987-09-02
ZA852382B (en) 1985-12-24
ATE29265T1 (de) 1987-09-15
US4665023A (en) 1987-05-12
CS276982B6 (en) 1992-11-18
ES551531A0 (es) 1987-01-01
IE850780L (en) 1985-09-30
DE3560531D1 (en) 1987-10-08
IE58212B1 (en) 1993-08-11
CA1259997A (en) 1989-09-26
CS231885A3 (en) 1992-04-15
HU199429B (en) 1990-02-28
AU4037685A (en) 1985-10-03
HUT37406A (en) 1985-12-28
CS725686A3 (en) 1992-04-15
JPH0643424B2 (ja) 1994-06-08
DK142985D0 (da) 1985-03-29

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Legal Events

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FD1A Patent lapsed

Effective date: 20060220