ES8207541A1 - Procedimiento para la preparacion de derivados de pirimidina - Google Patents

Procedimiento para la preparacion de derivados de pirimidina

Info

Publication number
ES8207541A1
ES8207541A1 ES503407A ES503407A ES8207541A1 ES 8207541 A1 ES8207541 A1 ES 8207541A1 ES 503407 A ES503407 A ES 503407A ES 503407 A ES503407 A ES 503407A ES 8207541 A1 ES8207541 A1 ES 8207541A1
Authority
ES
Spain
Prior art keywords
pyrimidine derivatives
preparation
medicaments containing
hydrogen
antiallergically
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES503407A
Other languages
English (en)
Other versions
ES503407A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
F Hoffmann La Roche AG
Original Assignee
F Hoffmann La Roche AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by F Hoffmann La Roche AG filed Critical F Hoffmann La Roche AG
Publication of ES503407A0 publication Critical patent/ES503407A0/es
Publication of ES8207541A1 publication Critical patent/ES8207541A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/26—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D333/38—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/14—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pulmonology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Immunology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA PREPARACION DE DERIVADOS DE PIRIMIDINA. CONSISTE EN HACER REACCIONAR DE FORMULA GENERAL (I) CON AMONIACO O CON UNA SOLUCION DE AMONIACO EN AGUA O EN ALCHOL (TAL COMO EL METANO) A UNA TEMPERATURA DE 0 A 150 GRADOS CENTIGRADOS-PREFERENTEMENTE PROXIMA A 120 GRADOS CENTIGRADOS- Y BAJO PRESION. TAMBIEN PUEDE EMPLEARSE COMO REACTIVO EL AMONIACO LIQUIDO. SE OBTIENE EL COMPUESTO (III) EN QUE R'' ES HIDROGENO, CLORO, BROMO O ALLQUILO C1-4 Y R2 ES HIDROGENO O METILO. PUEDEN OBTENERSE LAS FORMAS TAUTOMERAS DE COMPUESTO (II).
ES503407A 1980-06-27 1981-06-26 Procedimiento para la preparacion de derivados de pirimidina Expired ES8207541A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
CH499580 1980-06-27

Publications (2)

Publication Number Publication Date
ES503407A0 ES503407A0 (es) 1982-10-01
ES8207541A1 true ES8207541A1 (es) 1982-10-01

Family

ID=4286126

Family Applications (1)

Application Number Title Priority Date Filing Date
ES503407A Expired ES8207541A1 (es) 1980-06-27 1981-06-26 Procedimiento para la preparacion de derivados de pirimidina

Country Status (25)

Country Link
US (2) US4376121A (es)
EP (1) EP0043054B1 (es)
JP (1) JPS5762282A (es)
KR (1) KR840000705B1 (es)
AR (1) AR230748A1 (es)
AT (1) ATE9698T1 (es)
AU (1) AU7196781A (es)
BR (1) BR8103967A (es)
CA (1) CA1142924A (es)
CS (1) CS217997B2 (es)
CU (1) CU35489A (es)
DE (1) DE3166449D1 (es)
DK (1) DK252981A (es)
ES (1) ES8207541A1 (es)
FI (1) FI811600L (es)
GR (1) GR74943B (es)
HU (1) HU181608B (es)
IL (1) IL63145A (es)
MC (1) MC1395A1 (es)
NO (1) NO812208L (es)
NZ (1) NZ197476A (es)
PH (1) PH16060A (es)
PT (1) PT73270B (es)
ZA (1) ZA814162B (es)
ZW (1) ZW11781A1 (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ZW11781A1 (en) * 1980-06-27 1982-01-20 Hoffmann La Roche Pyrimidine derivatives
US4797486A (en) * 1986-09-08 1989-01-10 Pfizer Inc. Heterocyclic ring fused pyrimidine-4(3H)-ones as anticoccidial agents
US4725599A (en) * 1986-09-08 1988-02-16 Pfizer Inc. Heterocyclic ring fused pyrimidine-4 (3H)-ones as anticoccidial agents
DK522187D0 (da) * 1987-10-06 1987-10-06 Ferrosan As Imidozothienopyrimidiner, deres fremstilling og anvendelse
DK0888359T3 (da) 1996-03-11 2002-08-12 Syngenta Participations Ag Pyrimidin-4-on-derivat som pesticid
FR2872165B1 (fr) 2004-06-24 2006-09-22 Sod Conseils Rech Applic Nouveaux derives de pyrimido-benzimidazole
US8809346B2 (en) * 2008-05-30 2014-08-19 Universite De Versailles-Saint-Quentin-En-Yvelines ANT-ligands molecules and biological applications
CN104478851A (zh) * 2014-12-31 2015-04-01 济南诚汇双达化工有限公司 一种盐酸阿替卡因的制备方法

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE755404A (fr) * 1969-08-29 1971-03-01 Sandoz Sa Nouveau derives de la thiazolo-(3,2-a) pyrrolo (2,3-d) pyrimidine, leurpreparation et medicaments contenant ces derives
US3932407A (en) * 1973-11-19 1976-01-13 Bristol-Myers Company Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones
DE2411274A1 (de) * 1974-03-06 1975-09-18 Schering Ag Neue 2-nitrothieno eckige klammer auf 2,3-d eckige klammer zu pyrimidinon-derivate und verfahren zu ihrer herstellung
DE2411273A1 (de) * 1974-03-06 1975-09-18 Schering Ag Neue thieno eckige klammer auf 2,3-d eckige klammer zu pyrimidinone und verfahren zu ihrer herstellung
US4054656A (en) * 1975-09-10 1977-10-18 Mead Johnson & Company Thieno[2,3-d]pyrimidine antiallergic agents
JPS5527105A (en) * 1978-08-11 1980-02-27 Dai Ichi Seiyaku Co Ltd Imidazothienopyrimidinones compound
US4230707A (en) * 1979-08-27 1980-10-28 Warner-Lambert Company Oxo-pyrido[1,2-a]thienopyrimidine compounds and methods for their production
ZW11781A1 (en) * 1980-06-27 1982-01-20 Hoffmann La Roche Pyrimidine derivatives

Also Published As

Publication number Publication date
HU181608B (en) 1983-10-28
KR830006302A (ko) 1983-09-20
ZW11781A1 (en) 1982-01-20
PH16060A (en) 1983-06-09
ES503407A0 (es) 1982-10-01
US4442289A (en) 1984-04-10
CS217997B2 (en) 1983-02-25
ZA814162B (en) 1982-07-28
PT73270A (en) 1981-07-01
AR230748A1 (es) 1984-06-29
CU35489A (en) 1982-12-22
FI811600L (fi) 1981-12-28
JPS5762282A (en) 1982-04-15
NZ197476A (en) 1984-05-31
ATE9698T1 (de) 1984-10-15
EP0043054B1 (de) 1984-10-03
BR8103967A (pt) 1982-03-09
EP0043054A3 (en) 1982-03-17
CA1142924A (en) 1983-03-15
EP0043054A2 (de) 1982-01-06
PT73270B (en) 1983-05-11
DE3166449D1 (en) 1984-11-08
MC1395A1 (fr) 1982-04-27
KR840000705B1 (ko) 1984-05-21
AU7196781A (en) 1982-01-07
US4376121A (en) 1983-03-08
IL63145A0 (en) 1981-09-13
IL63145A (en) 1984-05-31
GR74943B (es) 1984-07-12
NO812208L (no) 1981-12-28
DK252981A (da) 1981-12-28

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