ES8503666A1 - Procedimiento para la preparacion de 1-ariloxi-2,3,4,5-tetrahidro-3-benzazepinas - Google Patents

Procedimiento para la preparacion de 1-ariloxi-2,3,4,5-tetrahidro-3-benzazepinas

Info

Publication number
ES8503666A1
ES8503666A1 ES523191A ES523191A ES8503666A1 ES 8503666 A1 ES8503666 A1 ES 8503666A1 ES 523191 A ES523191 A ES 523191A ES 523191 A ES523191 A ES 523191A ES 8503666 A1 ES8503666 A1 ES 8503666A1
Authority
ES
Spain
Prior art keywords
same
hydrogen
benzazepines
tetrahydro
aryloxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES523191A
Other languages
English (en)
Spanish (es)
Other versions
ES523191A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharmaceuticals Inc
Original Assignee
Hoechst Roussel Pharmaceuticals Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharmaceuticals Inc filed Critical Hoechst Roussel Pharmaceuticals Inc
Publication of ES523191A0 publication Critical patent/ES523191A0/es
Publication of ES8503666A1 publication Critical patent/ES8503666A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D223/00—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom
    • C07D223/14—Heterocyclic compounds containing seven-membered rings having one nitrogen atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D223/16—Benzazepines; Hydrogenated benzazepines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biomedical Technology (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
ES523191A 1982-06-14 1983-06-13 Procedimiento para la preparacion de 1-ariloxi-2,3,4,5-tetrahidro-3-benzazepinas Expired ES8503666A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US06/387,916 US4988690A (en) 1982-06-14 1982-06-14 1-aryloxy-2,3,4,5-tetrahydro-3-benzazepines and anti-depressant use thereof

Publications (2)

Publication Number Publication Date
ES523191A0 ES523191A0 (es) 1985-03-01
ES8503666A1 true ES8503666A1 (es) 1985-03-01

Family

ID=23531838

Family Applications (1)

Application Number Title Priority Date Filing Date
ES523191A Expired ES8503666A1 (es) 1982-06-14 1983-06-13 Procedimiento para la preparacion de 1-ariloxi-2,3,4,5-tetrahidro-3-benzazepinas

Country Status (17)

Country Link
US (1) US4988690A (enExample)
EP (1) EP0096838B1 (enExample)
JP (1) JPS595165A (enExample)
KR (1) KR900001214B1 (enExample)
AT (1) ATE26263T1 (enExample)
AU (1) AU570920B2 (enExample)
CA (1) CA1214460A (enExample)
DE (1) DE3370621D1 (enExample)
DK (1) DK270983A (enExample)
ES (1) ES8503666A1 (enExample)
FI (1) FI78473C (enExample)
GR (1) GR78291B (enExample)
HU (1) HU190902B (enExample)
IE (1) IE55404B1 (enExample)
IL (1) IL68964A (enExample)
PT (1) PT76864B (enExample)
ZA (1) ZA834309B (enExample)

Families Citing this family (24)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5015639A (en) * 1987-03-27 1991-05-14 Schering Corporation Substituted benzazepines, their preparation and pharmaceutical compositions containing them
ZA882080B (en) * 1987-03-27 1989-04-26 Schering Corp Substituted benzazepines,their preparation and pharmaceutical compositions containing them
CA1327795C (en) * 1987-08-14 1994-03-15 Jules Freedman Antidepressants which are aryloxy inadanamines
US5202319A (en) * 1991-09-23 1993-04-13 Hoechst-Roussel Pharmaceuticals Inc. Substituted 3-amino-2,3,4,5-tetrahydro-1-aryloxy-3-benzazepines
US5639482A (en) * 1993-11-10 1997-06-17 Crary; Ely J. Composition for control and prevention of diabetic retinopathy
US7115766B2 (en) * 2000-11-30 2006-10-03 Indiana University Research & Technology Corp. Nucleophilic approach for preparing radiolabeled imaging agents and associated compounds
US6953787B2 (en) * 2002-04-12 2005-10-11 Arena Pharmaceuticals, Inc. 5HT2C receptor modulators
CA2529320C (en) * 2003-06-17 2013-03-05 Arena Pharmaceuticals, Inc. Benzazepine derivatives useful for the treatment of 5ht2c receptor associated diseases
MXPA05013364A (es) 2003-06-17 2006-03-17 Arena Pharm Inc Procedimiento para preparar 3-benzazepinas.
US20070275949A1 (en) * 2003-10-22 2007-11-29 Arena Pharmaceuticals, Inc. Benzazepine Derivatives and Methods of Prophylaxis or Treatment of 5Ht2C Receptor Associated Diseases
US20080009478A1 (en) * 2003-10-22 2008-01-10 Arena Pharmaceuticals, Inc. Benzazepine Derivatives and Methods of Prophylaxis or Treatment of 5Ht2c Receptor Associated Diseases
ATE442359T1 (de) 2004-12-21 2009-09-15 Arena Pharm Inc Kristalline formen von (r)-8-chlor-1-methyl-2,3,4,5-tetrahydro-1h-3-be zazepinhydrochlorid
SG158168A1 (en) 2004-12-23 2010-01-29 Arena Pharm Inc 5ht2c receptor modulator compositions and methods of use
WO2007120517A2 (en) 2006-04-03 2007-10-25 Arena Pharmaceuticals, Inc. Processes for the preparation of 8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates related thereto
CA2670285A1 (en) * 2006-12-05 2008-06-12 Arena Pharmaceuticals, Inc. Processes for preparing (r)-8-chloro-1-methyl-2,3,4,5-tetrahydro-1h-3-benzazepine and intermediates thereof
AU2008251558B2 (en) * 2007-05-10 2012-12-20 Albany Molecular Research, Inc. Aryloxy-and heteroaryloxy-substituted tetrahydrobenzazepines and use thereof to block reuptake of norepinephrine, dopamine, and serotonin
CN102015591B (zh) 2008-03-04 2014-01-29 艾尼纳制药公司 制备与5-ht2c激动剂(r)-8-氯-1-甲基-2，3，4，5-四氢-1h-3-苯并氮杂卓相关的中间体的方法
US8952197B2 (en) 2009-06-18 2015-02-10 Arena Pharmaceuticals, Inc. Processes for the preparation of 5-HT2C receptor agonists
US9045431B2 (en) 2010-06-02 2015-06-02 Arena Pharmaceuticals, Inc. Processes for the preparation of 5-HT2C receptor agonists
CA3050049A1 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Modified-release dosage forms of 5-ht2c agonists useful for weight management
SG10201506896RA (en) 2010-09-01 2015-10-29 Arena Pharm Inc Administration of lorcaserin to individuals with renal impairment
CA2808904A1 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Non-hygroscopic salts of 5-ht2c agonists
CA2808909A1 (en) 2010-09-01 2012-03-08 Arena Pharmaceuticals, Inc. Salts of lorcaserin with optically active acids
MX2015004532A (es) 2012-10-09 2016-01-20 Arena Pharm Inc Metodo de control del peso.

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5233687A (en) * 1975-09-11 1977-03-14 Shionogi & Co Ltd Process for preparation of 1,5-dihydro-2h-1,4-benzodiazepine-2-on deri vatives
JPS5481290A (en) * 1977-11-17 1979-06-28 Smithkline Corp Benzazepin compound

Also Published As

Publication number Publication date
DK270983A (da) 1983-12-15
AU1576483A (en) 1983-12-22
FI832092L (fi) 1983-12-15
FI78473B (fi) 1989-04-28
HU190902B (en) 1986-12-28
KR900001214B1 (ko) 1990-02-28
IE831384L (en) 1983-12-14
EP0096838B1 (en) 1987-04-01
ZA834309B (en) 1984-03-28
ATE26263T1 (de) 1987-04-15
IL68964A (en) 1988-03-31
PT76864B (en) 1986-02-27
US4988690A (en) 1991-01-29
EP0096838A1 (en) 1983-12-28
GR78291B (enExample) 1984-09-26
DE3370621D1 (en) 1987-05-07
IE55404B1 (en) 1990-09-12
KR840005103A (ko) 1984-11-03
ES523191A0 (es) 1985-03-01
JPS595165A (ja) 1984-01-12
CA1214460A (en) 1986-11-25
PT76864A (en) 1983-07-01
IL68964A0 (en) 1983-10-31
FI832092A0 (fi) 1983-06-10
JPH0365342B2 (enExample) 1991-10-11
FI78473C (fi) 1989-08-10
DK270983D0 (da) 1983-06-13
AU570920B2 (en) 1988-03-31

Similar Documents

Publication Publication Date Title
ES8503666A1 (es) Procedimiento para la preparacion de 1-ariloxi-2,3,4,5-tetrahidro-3-benzazepinas
ES8707223A1 (es) Un procedimiento para la preparacion de derivados de benzotiazol y benzotiofen.
EP0353955A3 (en) Novel compounds
ES481873A1 (es) Procedimiento para la preparacion de 2-(2-alcoxietil)-2'- hidroxi-6,7-benzomorfanos.
IL107961A0 (en) Phenoxy- and phenoxyalkyl-piperidines and pharmaceutical compositions containing them
ES8401961A1 (es) Procedimiento para la preparacion de nuevas n-(4-indolil-piperidino-alcohil-bencimidazolonas sustituidas.
ZA8742B (en) Derivatives of decahydroquinoline,their preparation process,the preparation intermediates,their use as medicaments and the compositions containing them
ES8506652A1 (es) Un metodo de preparar dihidrobenzopirrolbenzodiazepinas
ES8800122A1 (es) Un procedimiento para la preparacion de derivados de indeno y naftaleno.
ES8601201A1 (es) Procedimiento para preparar derivados de imidazolina
ES8404854A1 (es) Procedimiento para la preparacion de compuestos de 1-fenil-2-aminocarbonilindol.
ES8308543A1 (es) "procedimiento para la preparacion de nuevas 2-fenil-2-(piridiloxi)-etilaminas sustituidas".
ES8504823A1 (es) Procedimiento para la preparacion de un nuevo compuesto heterociclico
ES8604218A1 (es) Un procedimiento para la preparacion de benzoquinolicinas
ES2003086A6 (es) Procedimiento de obtencion de tienoquinolicinsulfonamidas
DE3769451D1 (de) Indan-derivate, verfahren zu ihrer herstellung und die erhaltenen zwischenprodukte, ihre verwendung als arzneimittel und diese enthaltende zusammensetzungen.
ES8601099A1 (es) Procedimiento para la preparacion de nuevos derivados de n-(metoxifenacil)-amina
ES8406156A1 (es) Procedimiento para la preparacion de n-pteridinil-ureas(como divisional de la patente numero 521.331)
ES8106147A1 (es) Procedimiento para preparar un 1,2,4-triazol-3-tiol
JPS5636414A (en) Anticonvulsant agent containing omega-aminoalkoxystilbene or its acid addition salt as active constituent
MY104048A (en) New allylaminoethylazoles.
JPS57200397A (en) Novel aldohexopyranose-, aldopentopyranose-, or and medicament composition comprising it aldopentofuranose- nitrosourea compound, its preparation
ES8606325A1 (es) Procedimiento para preparar compuestos de 3-amino-2,3-dihi- dro-1-benzoxepina
BG50501A3 (bg) Метод за получаване на 1,5-бензтиазепинови производни