YU196082A - Process for preparing new heterocyclic compounds - Google Patents
Process for preparing new heterocyclic compoundsInfo
- Publication number
- YU196082A YU196082A YU01960/82A YU196082A YU196082A YU 196082 A YU196082 A YU 196082A YU 01960/82 A YU01960/82 A YU 01960/82A YU 196082 A YU196082 A YU 196082A YU 196082 A YU196082 A YU 196082A
- Authority
- YU
- Yugoslavia
- Prior art keywords
- carbon atoms
- alkyl
- phenyl
- hydrogen
- alkoxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/08—Antiallergic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D498/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Immunology (AREA)
- Pulmonology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Hydrogenated Pyridines (AREA)
- Lubricants (AREA)
- Gyroscopes (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Other In-Based Heterocyclic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Compounds of the formula <IMAGE> wherein R1, R2, R3 and R4 are each hydrogen, halogen, alkyl of 1 to 6 carbon atoms or alkoxy of 1 to 6 carbon atoms; R5 is hydrogen, alkyl of 1 to 6 carbon atoms or alkenyl of 3 to 6 carbon atoms; R6 is alkyl of 1 to 6 carbon atoms, alkenyl of 3 to 6 carbon atoms, phenyl, halo-phenyl, lower alkyl-phenyl, or lower alkoxy-phenyl or <IMAGE> R7 and R8 are each hydrogen, halogen, alkyl of 1 to 6 carbon atoms or alkoxy or 1 to 6 carbon atoms; n is an integer from 0 to 4, inclusive; x is -O-, -S-, or -CH2-; and the broken line between the 10 and 13b-positions indicates a single or double bond; and non-toxic, pharmacologically acceptable acid addition salts thereof; the compounds as well as their salts are useful as antiallergics and antithrombotics.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE19813134672 DE3134672A1 (en) | 1981-09-02 | 1981-09-02 | HETEROCYCLIC COMPOUNDS, THEIR PRODUCTION AND USE |
Publications (2)
Publication Number | Publication Date |
---|---|
YU196082A true YU196082A (en) | 1984-12-31 |
YU43089B YU43089B (en) | 1989-02-28 |
Family
ID=6140652
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
YU1960/82A YU43089B (en) | 1981-09-02 | 1982-08-31 | Process for preparing new 3-iminodibenzimidazo-azepines-oxazepines |
Country Status (26)
Country | Link |
---|---|
US (1) | US4503060A (en) |
EP (1) | EP0073506B1 (en) |
JP (1) | JPS5846089A (en) |
KR (1) | KR880001988B1 (en) |
AT (1) | ATE18049T1 (en) |
AU (1) | AU550340B2 (en) |
CA (1) | CA1169858A (en) |
CS (1) | CS236680B2 (en) |
DD (1) | DD204255A5 (en) |
DE (2) | DE3134672A1 (en) |
DK (1) | DK160047C (en) |
ES (3) | ES515413A0 (en) |
FI (1) | FI76089C (en) |
GB (1) | GB2108112B (en) |
GR (1) | GR77274B (en) |
HU (1) | HU185110B (en) |
IE (1) | IE54261B1 (en) |
IL (1) | IL66694A0 (en) |
NO (1) | NO160445C (en) |
NZ (1) | NZ201780A (en) |
PH (1) | PH19377A (en) |
PL (1) | PL135812B1 (en) |
PT (1) | PT75494B (en) |
SU (1) | SU1155158A3 (en) |
YU (1) | YU43089B (en) |
ZA (1) | ZA826380B (en) |
Families Citing this family (10)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US20020091850A1 (en) | 1992-10-23 | 2002-07-11 | Cybex Corporation | System and method for remote monitoring and operation of personal computers |
WO1995014671A1 (en) * | 1993-11-22 | 1995-06-01 | Merck & Co., Inc. | 3-acylaminobenzazepines |
CZ285008B6 (en) * | 1994-08-18 | 1999-04-14 | Merck & Co., Inc. | 2,3-dihydro-1-(2,2,2-trifluoroethyl)-2-oxo-5-phenyl-1h-1,4- benzodiazepine derivatives and pharmaceutical composition containing thereof |
US5478934A (en) * | 1994-11-23 | 1995-12-26 | Yuan; Jun | Certain 1-substituted aminomethyl imidazole and pyrrole derivatives: novel dopamine receptor subtype specific ligands |
US5700797A (en) * | 1995-06-07 | 1997-12-23 | Merck & Co, Inc. | N-(2,4-dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3-yl)-3-amides |
US5691331A (en) * | 1995-06-07 | 1997-11-25 | Merck & Co., Inc. | N-(2,4-Dioxo-2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-3yl) -3- amides |
US5726171A (en) * | 1995-06-07 | 1998-03-10 | Merck & Co Inc | N-(1-alkyl-5-phenyl-2,3,4,5-tetrahydro-1H-benzo B! 1,4!diazepin-3yl)-acetamides |
ES2193241T3 (en) * | 1995-06-07 | 2003-11-01 | Merck & Co Inc | NEW N-2-OXO2.3.4.5-TETRAJODRP-1H-1,5-BENZODIAZEPIN-3-IL) -3-AMIDAS. |
US5631251A (en) * | 1995-06-07 | 1997-05-20 | Merck & Co., Inc. | 5-cyclopropyl-1,4 benzodiazepine-2-ones |
CA2648115C (en) * | 2006-03-31 | 2015-03-24 | Vistakon Pharmaceuticals, Llc | Ocular allergy treatments |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
BE789410A (en) * | 1971-10-05 | 1973-01-15 | Akzo Nv | NIEUWE IMIDAZOLIDINE DERIVATEN |
NL7202963A (en) * | 1972-03-07 | 1973-09-11 | ||
NL7414038A (en) * | 1974-10-28 | 1976-05-03 | Akzo Nv | NEW TETRACYCLIC PYRROLIDINO DERIVATIVES. |
DE3008944A1 (en) * | 1980-03-08 | 1981-09-24 | C.H. Boehringer Sohn, 6507 Ingelheim | DIBENZIMIDAZOAZEPINE, THEIR PRODUCTION AND USE |
-
1981
- 1981-09-02 DE DE19813134672 patent/DE3134672A1/en not_active Withdrawn
-
1982
- 1982-08-20 US US06/410,006 patent/US4503060A/en not_active Expired - Fee Related
- 1982-08-23 PH PH27765A patent/PH19377A/en unknown
- 1982-08-27 JP JP57149040A patent/JPS5846089A/en active Granted
- 1982-08-28 DE DE8282107929T patent/DE3269187D1/en not_active Expired
- 1982-08-28 AT AT82107929T patent/ATE18049T1/en not_active IP Right Cessation
- 1982-08-28 EP EP82107929A patent/EP0073506B1/en not_active Expired
- 1982-08-30 CA CA000410412A patent/CA1169858A/en not_active Expired
- 1982-08-30 DD DD82242882A patent/DD204255A5/en unknown
- 1982-08-31 YU YU1960/82A patent/YU43089B/en unknown
- 1982-08-31 SU SU823484887A patent/SU1155158A3/en active
- 1982-08-31 FI FI823001A patent/FI76089C/en not_active IP Right Cessation
- 1982-08-31 GR GR69167A patent/GR77274B/el unknown
- 1982-08-31 PL PL1982238090A patent/PL135812B1/en unknown
- 1982-09-01 IL IL66694A patent/IL66694A0/en not_active IP Right Cessation
- 1982-09-01 ES ES515413A patent/ES515413A0/en active Granted
- 1982-09-01 CS CS826355A patent/CS236680B2/en unknown
- 1982-09-01 DK DK391182A patent/DK160047C/en not_active IP Right Cessation
- 1982-09-01 ZA ZA826380A patent/ZA826380B/en unknown
- 1982-09-01 AU AU87926/82A patent/AU550340B2/en not_active Ceased
- 1982-09-01 PT PT75494A patent/PT75494B/en not_active IP Right Cessation
- 1982-09-01 GB GB08224915A patent/GB2108112B/en not_active Expired
- 1982-09-01 NO NO822948A patent/NO160445C/en unknown
- 1982-09-01 IE IE2131/82A patent/IE54261B1/en not_active IP Right Cessation
- 1982-09-01 HU HU822808A patent/HU185110B/en not_active IP Right Cessation
- 1982-09-01 NZ NZ201780A patent/NZ201780A/en unknown
- 1982-09-02 KR KR8203956A patent/KR880001988B1/en active
-
1983
- 1983-04-19 ES ES521604A patent/ES8405017A1/en not_active Expired
- 1983-04-19 ES ES521605A patent/ES521605A0/en active Granted
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