BG50501A3 - Метод за получаване на 1,5-бензтиазепинови производни - Google Patents
Метод за получаване на 1,5-бензтиазепинови производниInfo
- Publication number
- BG50501A3 BG50501A3 BG085116A BG8511688A BG50501A3 BG 50501 A3 BG50501 A3 BG 50501A3 BG 085116 A BG085116 A BG 085116A BG 8511688 A BG8511688 A BG 8511688A BG 50501 A3 BG50501 A3 BG 50501A3
- Authority
- BG
- Bulgaria
- Prior art keywords
- radical
- benzthiazepine
- hydrogen
- methyl
- general formula
- Prior art date
Links
- KJFRSZASZNLCDF-UHFFFAOYSA-N 1,5-benzothiazepine Chemical class S1C=CC=NC2=CC=CC=C12 KJFRSZASZNLCDF-UHFFFAOYSA-N 0.000 title abstract 2
- -1 alkanoyl radical Chemical class 0.000 abstract 2
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- PXGOKWXKJXAPGV-UHFFFAOYSA-N Fluorine Chemical group FF PXGOKWXKJXAPGV-UHFFFAOYSA-N 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 150000001412 amines Chemical class 0.000 abstract 1
- 229910052801 chlorine Chemical group 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 229910052731 fluorine Inorganic materials 0.000 abstract 1
- 239000011737 fluorine Chemical group 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- WCYWZMWISLQXQU-UHFFFAOYSA-N methyl Chemical group [CH3] WCYWZMWISLQXQU-UHFFFAOYSA-N 0.000 abstract 1
- 125000002496 methyl group Chemical group [H]C([H])([H])* 0.000 abstract 1
- GRVDJDISBSALJP-UHFFFAOYSA-N methyloxidanyl Chemical group [O]C GRVDJDISBSALJP-UHFFFAOYSA-N 0.000 abstract 1
- 150000003254 radicals Chemical class 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
Получените по метода съединения намират приложение в лекарствената химия. 1,5-бензтиазепиновите произвоодни с обща формулав която r1 е метилов или метоксирадикал, r2 водород или нисш алканоилов радикал, единият r3 или r4 е метилов радикал, флуорен или хлорен атом, а другият водород, r5 и r6 нисш алкилов радикал, и техните фармацевтично приемливи кисели адитивни соли се получават при взаимодействие на съединение с обща формулав която r1, r2, r3 и r4 имат посочените значения, а х1 е реактивоспособен остатък, с амин с формула в която r5 и r6 имат посочените значения. 4 претенции
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP62202027A JPS6445376A (en) | 1987-08-12 | 1987-08-12 | Production of 1,5-benzothiazepine derivative |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| BG50501A3 true BG50501A3 (bg) | 1992-08-14 |
Family
ID=16450708
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| BG085116A BG50501A3 (bg) | 1987-08-12 | 1988-08-02 | Метод за получаване на 1,5-бензтиазепинови производни |
Country Status (14)
| Country | Link |
|---|---|
| JP (1) | JPS6445376A (bg) |
| KR (1) | KR890003722A (bg) |
| CN (1) | CN1030570C (bg) |
| AT (1) | AT395010B (bg) |
| BG (1) | BG50501A3 (bg) |
| CA (1) | CA1337346C (bg) |
| ES (1) | ES2007990A6 (bg) |
| FI (1) | FI883115A (bg) |
| GR (1) | GR1000385B (bg) |
| IE (1) | IE61168B1 (bg) |
| IL (1) | IL86978A0 (bg) |
| NO (1) | NO170017C (bg) |
| PT (1) | PT88250B (bg) |
| SU (1) | SU1709908A3 (bg) |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1236467A (en) * | 1967-10-28 | 1971-06-23 | Tanabe Seiyaku Co | Benzothiazepine derivatives |
| US3895006A (en) * | 1974-04-19 | 1975-07-15 | Squibb & Sons Inc | 5-(Substituted amino)alkyl)-2-aryl-3-halo-1,5-benzothiazepin-4(5H)-ones |
| SE449611B (sv) * | 1982-07-09 | 1987-05-11 | Tanabe Seiyaku Co | Sett att framstella 1,5-bensotiazepinderivat |
| GB8315364D0 (en) * | 1983-06-03 | 1983-07-06 | Tanabe Seiyaku Co | 8-chloro-1 5-benzothiazepine derivatives |
| US4567175A (en) * | 1983-06-03 | 1986-01-28 | Tanabe Seiyaku Co., Ltd. | 8-Chloro-1,5-benzothiazepine derivatives |
| GB8406318D0 (en) * | 1984-03-10 | 1984-04-11 | Tanabe Seiyaku Co | 1 5-benzothiazepine derivatives |
| JPS60204776A (ja) * | 1984-03-30 | 1985-10-16 | Roller Japan Kk | １，５−ベンゾチアゼピン誘導体 |
| JPS61103877A (ja) * | 1984-10-24 | 1986-05-22 | Tanabe Seiyaku Co Ltd | ベンゾチアゼピン誘導体及びその製法 |
-
1987
- 1987-08-12 JP JP62202027A patent/JPS6445376A/ja active Pending
-
1988
- 1988-06-27 IE IE194988A patent/IE61168B1/en not_active IP Right Cessation
- 1988-06-29 FI FI883115A patent/FI883115A/fi not_active Application Discontinuation
- 1988-07-04 IL IL86978A patent/IL86978A0/xx not_active IP Right Cessation
- 1988-07-07 CA CA000571438A patent/CA1337346C/en not_active Expired - Fee Related
- 1988-07-11 CN CN88104387A patent/CN1030570C/zh not_active Expired - Fee Related
- 1988-08-02 BG BG085116A patent/BG50501A3/bg unknown
- 1988-08-04 GR GR880100515A patent/GR1000385B/el unknown
- 1988-08-09 NO NO883525A patent/NO170017C/no unknown
- 1988-08-10 KR KR1019880010209A patent/KR890003722A/ko not_active Application Discontinuation
- 1988-08-11 AT AT0202388A patent/AT395010B/de not_active IP Right Cessation
- 1988-08-11 SU SU884356317A patent/SU1709908A3/ru active
- 1988-08-11 ES ES8802522A patent/ES2007990A6/es not_active Expired
- 1988-08-11 PT PT88250A patent/PT88250B/pt not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| FI883115A (fi) | 1989-02-13 |
| KR890003722A (ko) | 1989-04-17 |
| IL86978A0 (en) | 1988-12-30 |
| NO883525L (no) | 1989-02-13 |
| GR880100515A (en) | 1989-05-25 |
| NO883525D0 (no) | 1988-08-09 |
| CN1030570C (zh) | 1995-12-27 |
| ES2007990A6 (es) | 1989-07-01 |
| AT395010B (de) | 1992-08-25 |
| NO170017B (no) | 1992-05-25 |
| CN1031229A (zh) | 1989-02-22 |
| IE61168B1 (en) | 1994-10-05 |
| FI883115A0 (fi) | 1988-06-29 |
| JPS6445376A (en) | 1989-02-17 |
| SU1709908A3 (ru) | 1992-01-30 |
| GR1000385B (el) | 1992-06-30 |
| IE881949L (en) | 1989-02-12 |
| PT88250B (pt) | 1995-03-01 |
| CA1337346C (en) | 1995-10-17 |
| PT88250A (pt) | 1989-06-30 |
| ATA202388A (de) | 1992-01-15 |
| NO170017C (no) | 1992-09-02 |
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