ES8502098A1 - Procedimiento para preparar nuevas semicarbazidas - Google Patents

Procedimiento para preparar nuevas semicarbazidas

Info

Publication number
ES8502098A1
ES8502098A1 ES532177A ES532177A ES8502098A1 ES 8502098 A1 ES8502098 A1 ES 8502098A1 ES 532177 A ES532177 A ES 532177A ES 532177 A ES532177 A ES 532177A ES 8502098 A1 ES8502098 A1 ES 8502098A1
Authority
ES
Spain
Prior art keywords
carbon atoms
alkyl
phenyl
hydrogen
methyl
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES532177A
Other languages
English (en)
Other versions
ES532177A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Boehringer Ingelheim GmbH
Original Assignee
Boehringer Ingelheim GmbH
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim GmbH filed Critical Boehringer Ingelheim GmbH
Publication of ES8502098A1 publication Critical patent/ES8502098A1/es
Publication of ES532177A0 publication Critical patent/ES532177A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
    • C07D239/70—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings condensed with carbocyclic rings or ring systems
    • C07D239/72—Quinazolines; Hydrogenated quinazolines
    • C07D239/86—Quinazolines; Hydrogenated quinazolines with hetero atoms directly attached in position 4
    • C07D239/94—Nitrogen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives

Abstract

PROCEDIMIENTO PARA PREPARAR NUEVAS SEMICARBAZIDAS.CONSISTE EN HACER REACCIONAR UN COMPUESTO DE FORMULA (II) CON UN ISOCIANATO DE FORMULA (III) PARA OBTENER NUEVAS SEMICARBAZIDAS DE FORMULA (I), DONDE R1 ES H, ALCOHILO C 1 A 4 O TROFLUOROMETILO; R2, R3 Y R4 SON H, METILO O ETILO; R5 ES H ALCOHILO C 1 A 8, CICLO ALCOHILO C 3 A 7 Y OTROS. LA REACCION SE EFECTUA CON DISOLVENTES TAL COMO TETRAHIDROFURANO, DIOXANO, ETER Y OTROS, A TEMPERATURA ENTRE 0 Y 25JC.TIENEN APLICACION TERAPEUTICA POR SER INHIBIDORES DE FOSFORODIESTERASA Y ESTIMULANTES CARDIACOS CON LARGA DURACION DEL EFECTO.
ES532177A 1982-11-02 1984-05-04 Procedimiento para preparar nuevas semicarbazidas Granted ES532177A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19823240456 DE3240456A1 (de) 1982-11-02 1982-11-02 Neue semicarbazide, ihre herstellung und verwendung

Publications (2)

Publication Number Publication Date
ES8502098A1 true ES8502098A1 (es) 1984-12-16
ES532177A0 ES532177A0 (es) 1984-12-16

Family

ID=6177119

Family Applications (5)

Application Number Title Priority Date Filing Date
ES526919A Expired ES8501625A1 (es) 1982-11-02 1983-10-31 Procedimiento para preparar nuevas semicarbazidas
ES532178A Expired ES8502426A1 (es) 1982-11-02 1984-05-04 Procedimiento para preparar nuevas semicarbazidas
ES532177A Granted ES532177A0 (es) 1982-11-02 1984-05-04 Procedimiento para preparar nuevas semicarbazidas
ES532180A Expired ES8502428A1 (es) 1982-11-02 1984-05-04 Procedimiento para preparar nuevas semicarbazidas
ES532179A Granted ES532179A0 (es) 1982-11-02 1984-05-04 Procedimiento para preparar nuevas semicarbazidas

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES526919A Expired ES8501625A1 (es) 1982-11-02 1983-10-31 Procedimiento para preparar nuevas semicarbazidas
ES532178A Expired ES8502426A1 (es) 1982-11-02 1984-05-04 Procedimiento para preparar nuevas semicarbazidas

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES532180A Expired ES8502428A1 (es) 1982-11-02 1984-05-04 Procedimiento para preparar nuevas semicarbazidas
ES532179A Granted ES532179A0 (es) 1982-11-02 1984-05-04 Procedimiento para preparar nuevas semicarbazidas

Country Status (27)

Country Link
US (1) US4546102A (es)
EP (1) EP0108981B1 (es)
JP (1) JPH0625165B2 (es)
KR (1) KR910003117B1 (es)
AT (1) ATE18042T1 (es)
AU (1) AU561149B2 (es)
CA (1) CA1210001A (es)
CS (1) CS235987B2 (es)
DD (1) DD212512A5 (es)
DE (2) DE3240456A1 (es)
DK (1) DK157863C (es)
ES (5) ES8501625A1 (es)
FI (1) FI77237C (es)
GR (1) GR78947B (es)
HK (1) HK58389A (es)
HU (1) HU191889B (es)
IE (1) IE56183B1 (es)
IL (1) IL70103A (es)
NO (1) NO167201C (es)
NZ (1) NZ206120A (es)
PH (1) PH20225A (es)
PL (1) PL141232B1 (es)
PT (1) PT77572B (es)
SG (1) SG10889G (es)
SU (1) SU1179926A3 (es)
YU (1) YU216483A (es)
ZA (1) ZA838139B (es)

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE792856A (fr) * 1971-12-17 1973-06-15 Sandoz Sa Nouveaux derives de la triazolo-quinazoline, leur preparation et medicaments contenant ces
JPS55151570A (en) * 1979-05-15 1980-11-26 Takeda Chem Ind Ltd Pyrimidine derivatives, their preparation and antimicrobial for agriculture

Also Published As

Publication number Publication date
SU1179926A3 (ru) 1985-09-15
PL244355A1 (en) 1985-02-13
IE832550L (en) 1984-05-02
US4546102A (en) 1985-10-08
NZ206120A (en) 1986-05-09
IE56183B1 (en) 1991-05-08
EP0108981B1 (de) 1986-02-19
JPH0625165B2 (ja) 1994-04-06
SG10889G (en) 1989-09-29
PT77572B (de) 1986-05-27
DK501083D0 (da) 1983-11-01
AU561149B2 (en) 1987-04-30
JPS5998070A (ja) 1984-06-06
ES532178A0 (es) 1985-01-01
FI77237B (fi) 1988-10-31
ES526919A0 (es) 1984-12-01
ES8502426A1 (es) 1985-01-01
DE3240456A1 (de) 1984-05-03
IL70103A (en) 1987-01-30
ATE18042T1 (de) 1986-03-15
CS235987B2 (en) 1985-05-15
NO833978L (no) 1984-05-03
GR78947B (es) 1984-10-02
CA1210001A (en) 1986-08-19
PH20225A (en) 1986-10-23
YU216483A (en) 1986-04-30
DK501083A (da) 1984-05-03
ES8501625A1 (es) 1984-12-01
NO167201C (no) 1991-10-23
ES8502427A1 (es) 1985-01-01
FI833971A0 (fi) 1983-10-31
PL141232B1 (en) 1987-07-31
EP0108981A1 (de) 1984-05-23
DD212512A5 (de) 1984-08-15
IL70103A0 (en) 1984-02-29
KR910003117B1 (ko) 1991-05-18
ZA838139B (en) 1985-07-31
DK157863B (da) 1990-02-26
DE3362201D1 (en) 1986-03-27
ES532177A0 (es) 1984-12-16
DK157863C (da) 1990-08-06
KR840006632A (ko) 1984-12-01
FI77237C (fi) 1989-02-10
ES532180A0 (es) 1985-01-01
FI833971A (fi) 1984-05-03
HU191889B (en) 1987-04-28
PT77572A (de) 1983-11-01
ES8502428A1 (es) 1985-01-01
HK58389A (en) 1989-07-28
NO167201B (no) 1991-07-08
AU2092083A (en) 1984-05-10
ES532179A0 (es) 1985-01-01

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19971001