ES8501771A1 - Procedimiento para la preparacion de un nuevo compuesto heterociclico - Google Patents

Procedimiento para la preparacion de un nuevo compuesto heterociclico

Info

Publication number
ES8501771A1
ES8501771A1 ES531063A ES531063A ES8501771A1 ES 8501771 A1 ES8501771 A1 ES 8501771A1 ES 531063 A ES531063 A ES 531063A ES 531063 A ES531063 A ES 531063A ES 8501771 A1 ES8501771 A1 ES 8501771A1
Authority
ES
Spain
Prior art keywords
preparation
heterocyclic compounds
medicines containing
substituted
medicines
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES531063A
Other languages
English (en)
Other versions
ES531063A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Rhone Poulenc Sante SA
Original Assignee
Rhone Poulenc Sante SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Rhone Poulenc Sante SA filed Critical Rhone Poulenc Sante SA
Publication of ES531063A0 publication Critical patent/ES531063A0/es
Publication of ES8501771A1 publication Critical patent/ES8501771A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/06Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/54Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
    • C07D213/55Acids; Esters
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D279/00Heterocyclic compounds containing six-membered rings having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D279/041,3-Thiazines; Hydrogenated 1,3-thiazines
    • C07D279/061,3-Thiazines; Hydrogenated 1,3-thiazines not condensed with other rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/06Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/06Peri-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D513/00Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Diabetes (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyrrole Compounds (AREA)
  • Polyoxymethylene Polymers And Polymers With Carbon-To-Carbon Bonds (AREA)
  • Silicon Polymers (AREA)
  • Earth Drilling (AREA)
  • Peptides Or Proteins (AREA)
  • Instructional Devices (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Materials For Medical Uses (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE COMPUESTOS HETEROCICLICOS Y DE SUS SALES DE ADICION DE ACIDOS, DE FORMULA (I), EN LA QUE A Y R3 PUEDEN SER VARIOS RADICALES; Y M, N Y P VALEN 1 O 2, 0-2 Y 0 O 1, RESPECTIVAMENTE.CONSISTE EN LA REACCION DE CONDENSACION DE CLORO-2-ACRILAMIDA CON UN ACIDO DE FORMULA (II), EN LA QUE TODOS LOS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I), SEGUIDA DE LA SEPARACION DEL PRODUCTO OBTENIDO.ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE AFECCIONES TROMBOTICAS.
ES531063A 1983-01-13 1984-03-28 Procedimiento para la preparacion de un nuevo compuesto heterociclico Expired ES8501771A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR8300454A FR2539417A1 (fr) 1983-01-13 1983-01-13 Nouveaux pyrrolo-1, 2 heterocycles, leur preparation et les medicaments qui les contiennent

Publications (2)

Publication Number Publication Date
ES531063A0 ES531063A0 (es) 1984-12-01
ES8501771A1 true ES8501771A1 (es) 1984-12-01

Family

ID=9284899

Family Applications (3)

Application Number Title Priority Date Filing Date
ES528874A Expired ES8502122A1 (es) 1983-01-13 1984-01-13 Procedimiento para la preparacion de nuevos compuestos carboxamidicos de pirrol ortocondensado.
ES531063A Expired ES8501771A1 (es) 1983-01-13 1984-03-28 Procedimiento para la preparacion de un nuevo compuesto heterociclico
ES531062A Granted ES531062A0 (es) 1983-01-13 1984-03-28 Procedimiento para la preparacion de un nuevo compuesto heterociclico

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES528874A Expired ES8502122A1 (es) 1983-01-13 1984-01-13 Procedimiento para la preparacion de nuevos compuestos carboxamidicos de pirrol ortocondensado.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES531062A Granted ES531062A0 (es) 1983-01-13 1984-03-28 Procedimiento para la preparacion de un nuevo compuesto heterociclico

Country Status (26)

Country Link
US (2) US4546100A (es)
EP (1) EP0118321B1 (es)
JP (1) JPS59134797A (es)
KR (1) KR910001284B1 (es)
AT (1) ATE24321T1 (es)
AU (1) AU562832B2 (es)
BG (4) BG40968A3 (es)
CA (1) CA1222514A (es)
CS (1) CS259516B2 (es)
DD (1) DD216022A5 (es)
DE (1) DE3461713D1 (es)
DK (1) DK13884A (es)
ES (3) ES8502122A1 (es)
FI (1) FI76578C (es)
FR (1) FR2539417A1 (es)
GR (1) GR81680B (es)
HU (1) HU194224B (es)
IE (1) IE56838B1 (es)
IL (1) IL70663A (es)
MA (1) MA20002A1 (es)
NO (1) NO167032C (es)
NZ (1) NZ206809A (es)
PL (4) PL144351B1 (es)
PT (1) PT77951B (es)
SU (6) SU1251805A3 (es)
ZA (1) ZA84234B (es)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2557111B1 (fr) * 1983-12-21 1986-04-11 Rhone Poulenc Sante Nouveaux derives ortho-condenses du pyrrole, leur preparation et les medicaments qui les contiennent
GB8903592D0 (en) * 1989-02-16 1989-04-05 Boots Co Plc Therapeutic agents
US5260451A (en) * 1989-05-11 1993-11-09 Merckle Gmbh Substituted pyrrole compounds and use thereof in pharmaceutical compositions
DE3915450A1 (de) * 1989-05-11 1990-11-15 Gerd Prof Dr Dannhardt Substituierte pyrrolverbindungen und deren anwendung in der pharmazie
JP3061631B2 (ja) * 1989-10-11 2000-07-10 山之内製薬株式会社 新規なヘテロ環化合物およびその製造法
DE4419247A1 (de) * 1994-06-01 1995-12-07 Merckle Gmbh Sulfonylierte Pyrrolizincarbonsäureamide und deren Anwendung in der Pharmazie
DE4419246A1 (de) * 1994-06-01 1995-12-07 Merckle Gmbh Heteroarylsubstituierte Pyrrolizinverbindungen und deren Anwendung in der Pharmazie
FR2735476B1 (fr) * 1995-06-14 1997-07-18 Rhone Poulenc Rorer Sa Nouvelle application de derives du pyrrole
WO2001005792A1 (de) 1999-11-23 2001-01-25 Merckle Gmbh Antiinflammatorische oxo- und hydroxyderivate von pyrrolizinen und deren anwendung in der pharmazie
DE10004157A1 (de) 2000-02-01 2001-08-02 Merckle Gmbh Chem Pharm Fabrik 4-Pyridyl-und 2,4-Pyrimidinyl-substituierte Pyrrolderivate und ihre Anwendung in der Pharmazie
US8424704B2 (en) * 2004-06-02 2013-04-23 X-Pert Paint Mixing Systems, Inc. Self-cleaning lid for a paint container fluid pour spout

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR1401707A (fr) * 1963-07-03 1965-06-04 Kodak Pathe Nouveaux colorants, nouveaux composés intermédiaires servant à les préparer et produits photographiques les contenant
BE649903A (es) * 1963-07-03
US3642807A (en) * 1970-06-18 1972-02-15 Schering Corp Certain 1-/dilower-alkyl amino-loweralkyl/-2-phenyl indolizines and quaternary salts thereof

Also Published As

Publication number Publication date
FI840107A (fi) 1984-07-14
US4546100A (en) 1985-10-08
DE3461713D1 (en) 1987-01-29
ES531063A0 (es) 1984-12-01
SU1297730A3 (ru) 1987-03-15
DK13884D0 (da) 1984-01-12
ES8504823A1 (es) 1985-04-16
BG40968A3 (en) 1987-03-14
IL70663A0 (en) 1984-04-30
JPS59134797A (ja) 1984-08-02
SU1282818A3 (ru) 1987-01-07
DK13884A (da) 1984-07-14
EP0118321B1 (fr) 1986-12-17
BG40146A3 (en) 1986-10-15
IE56838B1 (en) 1992-01-01
PL142322B1 (en) 1987-10-31
ES528874A0 (es) 1984-12-16
SU1251805A3 (ru) 1986-08-15
PT77951A (fr) 1984-02-01
BG40148A3 (en) 1986-10-15
MA20002A1 (fr) 1984-10-01
JPH0576479B2 (es) 1993-10-22
IL70663A (en) 1987-08-31
HUT34190A (en) 1985-02-28
CS19884A2 (en) 1988-03-15
PL245704A1 (en) 1985-05-21
FR2539417B1 (es) 1985-03-15
PL245702A1 (en) 1985-05-21
DD216022A5 (de) 1984-11-28
US4584297A (en) 1986-04-22
FI76578C (fi) 1988-11-10
NO167032C (no) 1991-09-25
ES8502122A1 (es) 1984-12-16
BG40147A3 (en) 1986-10-15
PL251479A1 (en) 1985-07-02
PL144351B1 (en) 1988-05-31
NO167032B (no) 1991-06-17
AU2320184A (en) 1984-07-19
CA1222514A (fr) 1987-06-02
PT77951B (fr) 1986-06-26
FI840107A0 (fi) 1984-01-12
HU194224B (en) 1988-01-28
AU562832B2 (en) 1987-06-18
ATE24321T1 (de) 1987-01-15
PL144341B1 (en) 1988-05-31
ZA84234B (en) 1984-08-29
SU1282819A3 (ru) 1987-01-07
NZ206809A (en) 1986-05-09
PL251478A1 (en) 1985-07-02
IE840063L (en) 1984-07-13
SU1251808A3 (ru) 1986-08-15
GR81680B (es) 1984-12-12
FR2539417A1 (fr) 1984-07-20
SU1277900A3 (ru) 1986-12-15
ES531062A0 (es) 1985-04-16
KR840007418A (ko) 1984-12-07
KR910001284B1 (ko) 1991-02-28
EP0118321A1 (fr) 1984-09-12
CS259516B2 (en) 1988-10-14
PL144350B1 (en) 1988-05-31
NO840107L (no) 1984-07-16
FI76578B (fi) 1988-07-29

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519