ES8407045A1 - Un procedimiento para la preparacion de 2-cuanidino-4-imidazoliltiazoles. - Google Patents
Un procedimiento para la preparacion de 2-cuanidino-4-imidazoliltiazoles.Info
- Publication number
- ES8407045A1 ES8407045A1 ES522223A ES522223A ES8407045A1 ES 8407045 A1 ES8407045 A1 ES 8407045A1 ES 522223 A ES522223 A ES 522223A ES 522223 A ES522223 A ES 522223A ES 8407045 A1 ES8407045 A1 ES 8407045A1
- Authority
- ES
- Spain
- Prior art keywords
- antiulcer
- thiazoles
- guanidino
- imidazolyl
- amino
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/88—Nitrogen atoms, e.g. allantoin
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D263/34—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/48—Nitrogen atoms not forming part of a nitro radical
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Engineering & Computer Science (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Cephalosporin Compounds (AREA)
- Analysing Materials By The Use Of Radiation (AREA)
- Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
- Lubricants (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Peptides Or Proteins (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/376,486 US4435396A (en) | 1982-05-10 | 1982-05-10 | Antiulcer 2-guanidino-4-(2-substituted-amino-4-imidazolyl)thiazoles and process therefor |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| ES522223A0 ES522223A0 (es) | 1984-08-16 |
| ES8407045A1 true ES8407045A1 (es) | 1984-08-16 |
Family
ID=23485203
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES522223A Expired ES8407045A1 (es) | 1982-05-10 | 1983-05-09 | Un procedimiento para la preparacion de 2-cuanidino-4-imidazoliltiazoles. |
Country Status (26)
| Country | Link |
|---|---|
| US (1) | US4435396A (OSRAM) |
| EP (1) | EP0094191B1 (OSRAM) |
| JP (1) | JPS58206588A (OSRAM) |
| KR (1) | KR860000931B1 (OSRAM) |
| AT (1) | ATE33649T1 (OSRAM) |
| AU (2) | AU539244B2 (OSRAM) |
| CA (1) | CA1201120A (OSRAM) |
| CS (1) | CS252461B2 (OSRAM) |
| DD (1) | DD209828A5 (OSRAM) |
| DE (1) | DE3376322D1 (OSRAM) |
| DK (1) | DK163829B (OSRAM) |
| EG (1) | EG17029A (OSRAM) |
| ES (1) | ES8407045A1 (OSRAM) |
| FI (1) | FI78481C (OSRAM) |
| GR (1) | GR79279B (OSRAM) |
| GT (1) | GT198302123A (OSRAM) |
| HU (2) | HU196377B (OSRAM) |
| IE (1) | IE55229B1 (OSRAM) |
| IL (1) | IL68630A (OSRAM) |
| NO (1) | NO159932C (OSRAM) |
| NZ (1) | NZ204158A (OSRAM) |
| PL (1) | PL141199B1 (OSRAM) |
| PT (1) | PT76662B (OSRAM) |
| SU (1) | SU1195907A3 (OSRAM) |
| YU (1) | YU42857B (OSRAM) |
| ZA (1) | ZA833286B (OSRAM) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4673677A (en) * | 1983-10-03 | 1987-06-16 | Pfizer Inc. | Method for treatment of gastrointestinal disorders |
| US4554276A (en) * | 1983-10-03 | 1985-11-19 | Pfizer Inc. | 2-Amino-5-hydroxy-4-methylpyrimidine derivatives |
| US4560690A (en) * | 1984-04-30 | 1985-12-24 | Pfizer Inc. | 2-(N-substituted guanidino)-4-hetero-arylthiazole antiulcer agents |
| US4632993A (en) * | 1984-10-11 | 1986-12-30 | Pfizer Inc. | Process for making 2-guanidino-4-(2-methyl-4-imidazolyl) thiazole dihydrobromide |
| US4636498A (en) * | 1984-10-11 | 1987-01-13 | Pfizer Inc. | Formulation of antiinflammatory drugs |
| WO1986003203A1 (fr) * | 1984-11-22 | 1986-06-05 | Yoshitomi Pharmaceutical Industries, Ltd. | Derives de thienylthiazole |
| US4814341A (en) * | 1986-08-26 | 1989-03-21 | Reiter Lawrence A | 2-guanidino-4-(2-furyl) thiazoles as antiulcer agents |
| ATE66477T1 (de) * | 1986-08-29 | 1991-09-15 | Pfizer | 2-guanidino-4-aryl-thiazole fuer die behandlung von peptischen geschwueren. |
| EP0269239B1 (en) * | 1986-10-29 | 1994-06-08 | Pfizer Inc. | Processes for 2-(1-pentyl-3-guanidino)-4-(2-methyl-4-imidazolyl)thiazole and the crystalline dihydrochloride trihydrate thereof |
| AU6436394A (en) * | 1993-06-15 | 1995-01-03 | Pfizer Inc. | H2-antagonists as immune stimulants in bacterial infections of cattle or swine |
| BRPI0919004A2 (pt) | 2008-09-22 | 2019-09-24 | Cayman Chem Co | composto de multiheteroarila como inibidores de h-pgds e sua utilização para o tratamento de doenças mediadas por prostaglandina d2 |
| EP4196793A1 (en) | 2020-08-11 | 2023-06-21 | Université de Strasbourg | H2 blockers targeting liver macrophages for the prevention and treatment of liver disease and cancer |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3519637A (en) | 1966-12-06 | 1970-07-07 | Hoffmann La Roche | 1-(4-thiazolylmethyl)nitroimidazole derivatives |
| DE2142585A1 (de) * | 1971-08-20 | 1973-02-22 | Schering Ag | 2-(5-nitro-2-thiazolyl)-benzimidazole |
| FR2284601A1 (fr) * | 1974-09-10 | 1976-04-09 | Inst Francais Du Petrole | Composes guanidino-heterocycliques alkyles, leur preparation et leur utilisation comme additifs pour carburants et lubrifiants |
| US4220654A (en) | 1979-06-04 | 1980-09-02 | Merck & Co., Inc. | Cyclic imidazole cyanoguanidines |
| US4374843A (en) * | 1980-10-14 | 1983-02-22 | Pfizer Inc. | 2-Guanidino-4-heteroarylthiazoles |
-
1982
- 1982-05-10 US US06/376,486 patent/US4435396A/en not_active Expired - Fee Related
-
1983
- 1983-05-03 SU SU833585699A patent/SU1195907A3/ru active
- 1983-05-04 DE DE8383302495T patent/DE3376322D1/de not_active Expired
- 1983-05-04 AT AT83302495T patent/ATE33649T1/de not_active IP Right Cessation
- 1983-05-04 EP EP83302495A patent/EP0094191B1/en not_active Expired
- 1983-05-04 GR GR71297A patent/GR79279B/el unknown
- 1983-05-05 YU YU996/83A patent/YU42857B/xx unknown
- 1983-05-05 CS CS833184A patent/CS252461B2/cs unknown
- 1983-05-06 CA CA000427596A patent/CA1201120A/en not_active Expired
- 1983-05-06 HU HU862387A patent/HU196377B/hu not_active IP Right Cessation
- 1983-05-06 PL PL1983241840A patent/PL141199B1/pl unknown
- 1983-05-06 HU HU831581A patent/HU190899B/hu not_active IP Right Cessation
- 1983-05-06 GT GT198302123A patent/GT198302123A/es unknown
- 1983-05-06 NZ NZ204158A patent/NZ204158A/en unknown
- 1983-05-07 EG EG275/83A patent/EG17029A/xx active
- 1983-05-09 DD DD83250744A patent/DD209828A5/de not_active IP Right Cessation
- 1983-05-09 IE IE1061/83A patent/IE55229B1/en unknown
- 1983-05-09 ES ES522223A patent/ES8407045A1/es not_active Expired
- 1983-05-09 NO NO831632A patent/NO159932C/no unknown
- 1983-05-09 PT PT76662A patent/PT76662B/pt unknown
- 1983-05-09 AU AU14363/83A patent/AU539244B2/en not_active Ceased
- 1983-05-09 KR KR1019830001962A patent/KR860000931B1/ko not_active Expired
- 1983-05-09 ZA ZA833286A patent/ZA833286B/xx unknown
- 1983-05-09 DK DK205883A patent/DK163829B/da not_active Application Discontinuation
- 1983-05-09 FI FI831595A patent/FI78481C/fi not_active IP Right Cessation
- 1983-05-09 IL IL68630A patent/IL68630A/xx unknown
- 1983-05-10 JP JP58081601A patent/JPS58206588A/ja active Pending
-
1984
- 1984-07-18 AU AU30815/84A patent/AU566755B2/en not_active Ceased
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM4A | Patent lapsed |
Effective date: 19960506 |