ES8401446A1 - "un procedimiento para preparar un compuesto peptidico". - Google Patents

"un procedimiento para preparar un compuesto peptidico".

Info

Publication number
ES8401446A1
ES8401446A1 ES512892A ES512892A ES8401446A1 ES 8401446 A1 ES8401446 A1 ES 8401446A1 ES 512892 A ES512892 A ES 512892A ES 512892 A ES512892 A ES 512892A ES 8401446 A1 ES8401446 A1 ES 8401446A1
Authority
ES
Spain
Prior art keywords
glu
gln
leu
ala
lys
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES512892A
Other languages
English (en)
Other versions
ES512892A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Salk Institute for Biological Studies
Original Assignee
Salk Institute for Biological Studies
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Salk Institute for Biological Studies filed Critical Salk Institute for Biological Studies
Publication of ES8401446A1 publication Critical patent/ES8401446A1/es
Publication of ES512892A0 publication Critical patent/ES512892A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575—Hormones
    • C07K14/57509—Corticotropin releasing factor [CRF] (Urotensin)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P5/00—Drugs for disorders of the endocrine system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Molecular Biology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biochemistry (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Polyesters Or Polycarbonates (AREA)
  • Train Traffic Observation, Control, And Security (AREA)
  • Developing Agents For Electrophotography (AREA)
  • Heat Sensitive Colour Forming Recording (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Electrotherapy Devices (AREA)
  • Control Of Eletrric Generators (AREA)
  • Measuring Pulse, Heart Rate, Blood Pressure Or Blood Flow (AREA)
  • Vehicle Body Suspensions (AREA)

Abstract

PROCEDIMIENTO PARA PREPARAR UN COMPUESTO PEPTIDICO.COMPRENDE LAS SIGUIENTES FASES: PRIMERA, SE HACE REACCIONAR UN COMPUESTO DE FORMULA: X1-R1-PRO-PRO-ILE-SER(X2)-R8-ASP(X5)-LEU-R11 (X2)-R12-R13-LEU-LEUKARG(X3) -R17-R18-R19-GLU(X5)-R21 -R22- LYS(X6)-R24-R25-R26 -R27-R28-GLN(X4)-GLN(X4)-ALA -R32-R33-ASN(X4)-ARG(X3) -R36-LEU-LEU-ASP(X5)-R40-R41-X7, CON UN SOPORTE DE RESINA DE -O-CH2-POLIESTIRENO, PARA FORMAR UN COMPUESTO INTERMEDIO DE POLIPEPTIDO; SEGUNDA, MEDIANTE UNA REACCION DE DESPROTECCION SE ELIMINAN UNO O MAS GRUPOS DE PROTECCION DEL POLIPEPTIDO INTERMEDIO; Y POR ULTIMO, SE PURIFICA EL COMPUESTO POLIPEPTIDO RESULTANTE.DEAPLICACION EN FARMACIA PARA LA PREPARACION DE COMPOSICIONES UTILIZADAS EN EL TRATAMIENTO DE LOS MAMIFEROS.
ES512892A 1981-06-08 1982-06-07 "un procedimiento para preparar un compuesto peptidico". Granted ES512892A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US27162481A 1981-06-08 1981-06-08

Publications (2)

Publication Number Publication Date
ES8401446A1 true ES8401446A1 (es) 1983-12-01
ES512892A0 ES512892A0 (es) 1983-12-01

Family

ID=23036364

Family Applications (1)

Application Number Title Priority Date Filing Date
ES512892A Granted ES512892A0 (es) 1981-06-08 1982-06-07 "un procedimiento para preparar un compuesto peptidico".

Country Status (15)

Country Link
EP (1) EP0067608B1 (es)
JP (1) JPS57212149A (es)
KR (1) KR890002774B1 (es)
AT (1) ATE6505T1 (es)
AU (1) AU554676B2 (es)
CA (1) CA1243301A (es)
DE (1) DE3260057D1 (es)
DK (1) DK156957C (es)
ES (1) ES512892A0 (es)
GR (1) GR75679B (es)
IE (1) IE53488B1 (es)
IL (1) IL65937A (es)
NZ (1) NZ200711A (es)
PH (1) PH20364A (es)
ZA (1) ZA823635B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE88481T1 (de) * 1984-02-23 1993-05-15 Salk Inst For Biological Studi Crf-analoga.
CA1341051C (en) * 1988-09-23 2000-07-11 Jean Edouard Frederic Rivier Crf antagonists
CA2002004A1 (en) * 1988-11-14 1990-05-14 Karl P. Lederis Fish crf
US5235036A (en) * 1991-05-31 1993-08-10 The Salk Institute For Biological Studies Crf analogs
DE4110422A1 (de) * 1991-03-29 1992-10-01 Bissendorf Peptide Gmbh Arzneimittel enthaltend humanes corticotropin-releasing hormon (crh) und/oder dessen derivate und/oder glucocorticoide natuerlicher und/oder synthetischer provenienz
EP0781140A4 (en) * 1994-09-12 1999-11-03 Univ Pennsylvania FACTOR INHIBITING THE CORTICOTROPIN RELEASE AND METHOD FOR ITS USE
US6039956A (en) * 1994-09-12 2000-03-21 Pennsylvania, Trustees Of The University Of, The Corticotropin release inhibiting factor and methods of using same for treating behavioral symptoms in an anxiety disorder
KR102259056B1 (ko) 2017-12-29 2021-06-01 (주)에스엠테크 디아민 화합물과 알루미네이트계 화합물을 포함하는 광물 미분쇄용 분쇄조제 조성물 및 이를 사용한 광물의 미분쇄방법
KR20200121309A (ko) 2018-02-16 2020-10-23 제이엔씨 주식회사 중합성 화합물, 중합성 조성물, 중합체 및 포토레지스트용 조성물

Also Published As

Publication number Publication date
JPS57212149A (en) 1982-12-27
PH20364A (en) 1986-12-04
IE821330L (en) 1982-12-08
AU8445582A (en) 1982-12-16
CA1243301A (en) 1988-10-18
EP0067608A1 (en) 1982-12-22
EP0067608B1 (en) 1984-03-07
AU554676B2 (en) 1986-08-28
DE3260057D1 (en) 1984-04-12
DK254982A (da) 1982-12-09
ES512892A0 (es) 1983-12-01
DK156957C (da) 1990-03-19
IE53488B1 (en) 1988-11-23
GR75679B (es) 1984-08-02
ATE6505T1 (de) 1984-03-15
KR890002774B1 (ko) 1989-07-28
IL65937A0 (en) 1982-09-30
ZA823635B (en) 1983-03-30
JPS642600B2 (es) 1989-01-18
IL65937A (en) 1986-09-30
DK156957B (da) 1989-10-23
KR840000477A (ko) 1984-02-22
NZ200711A (en) 1986-02-21

Similar Documents

Publication Publication Date Title
PT83278A (en) Process for the preparation of insulin analogues and of injectable insulin solutions containing the same
KR880009045A (ko) 혈액 응고 방지성 펩티드
DE3875538D1 (de) Aminoluciferine, verfahren zu deren herstellung und ihre verwendung.
KR840009075A (ko) Crf-상사체의 제법
KR880006263A (ko) 신규의 캘시토닌 유도체의 제조방법
DE3260057D1 (en) Crf and analogs
KR870007203A (ko) 펩타이드를 제조하는 방법
KR840007569A (ko) Grf 유사체 펩티드의 제법
KR880013977A (ko) 항응고제인 사이클릭 펩타이드
EP0751148A3 (en) D-amino acid substitution analogues of magainin peptides
KR830007516A (ko) 폴리펩타이드 조성물
NZ207378A (en) Leu 27 - and nle 27 -grf (human growth hormone releasing factor), preparation and pharmaceutical composition
KR910007960A (ko) 항응고성 펩티드
CA2045495A1 (en) Peptides and processes for producing cyclic peptides
KR900009699A (ko) 항응고성 펩타이드 및 이의 제조방법
KR850700246A (ko) Crf 유사체
GB992957A (en) New decapeptides and their manufacture
CA2076749A1 (en) Vasoactive vasotocin derivatives
US4389342A (en) Synthetic hormone-like peptides and method for their synthesis
GB1477001A (en) Process for the manufacture of peptides containing more han one cystine residue
CA1090784A (en) Synthesis for peptides
EP0147175A3 (en) Novel basic polypeptides and a method of producing thereof
GB1587809A (en) Synthesis of peptides
AT271745B (de) Verfahren zur Herstellung von neuen Peptiden
KR870007206A (ko) 폴리펩타이드 화합물