ES8300773A1 - "un procedimiento para la preparacion de derivados de metoxicefalosporinas". - Google Patents

"un procedimiento para la preparacion de derivados de metoxicefalosporinas".

Info

Publication number
ES8300773A1
ES8300773A1 ES508723A ES508723A ES8300773A1 ES 8300773 A1 ES8300773 A1 ES 8300773A1 ES 508723 A ES508723 A ES 508723A ES 508723 A ES508723 A ES 508723A ES 8300773 A1 ES8300773 A1 ES 8300773A1
Authority
ES
Spain
Prior art keywords
alpha
onctaining
same
antibacterial drugs
derivatives
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES508723A
Other languages
English (en)
Other versions
ES508723A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Eisai Co Ltd
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP2611280A external-priority patent/JPS56122384A/ja
Priority claimed from JP9219980A external-priority patent/JPS5718689A/ja
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of ES8300773A1 publication Critical patent/ES8300773A1/es
Publication of ES508723A0 publication Critical patent/ES508723A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/24—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with hydrocarbon radicals, substituted by hetero atoms or hetero rings, attached in position 3
    • C07D501/36—Methylene radicals, substituted by sulfur atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
    • C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/14—Compounds having a nitrogen atom directly attached in position 7
    • C07D501/16—Compounds having a nitrogen atom directly attached in position 7 with a double bond between positions 2 and 3
    • C07D501/20—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids
    • C07D501/57—7-Acylaminocephalosporanic or substituted 7-acylaminocephalosporanic acids in which the acyl radicals are derived from carboxylic acids with a further substituent in position 7, e.g. cephamycines

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS DE METOXICEFALOSPORINAS Y DE SUS SALES FISIOLOGICAMENTE COMPATIBLES, DE FORMULA (I), EN LA QUE R ES HIDROGENO O HIDROXI; R -R PUEDEN SER VARIOS TIPOS DE RADICALES; Y R ES HIDROGENO O HIDROXI; R -R PUEDEN SER VARIOS TIPOS DE RADICALES; Y R ES CARBOXIALCOHILTIO O HETEROCICLOTIO QUE CONTIENE NITROGENO. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (I) EN LA QUE R ES EL GRUPO OCOCH Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO INDICADO ANTERIORMENTE, O UNA SAL O HIDRATO DEL MISMO, CON UN COMPUESTO DE FORMULA R H, EN LA QUE R ES CARBOXIALCOHILTIO O HETEROCICLOTIO QUE CONTIENE NITROGENO. LA REACCION SE LLEVA A CABO EN AGUA, UNA DISOLUCION TAMPON, EN PRESENCIA DE BICABONATO SODICO, HIDROXIDO SODICO O SIMILARES, A UNA TEMPERATURA ENTRE 50<025>C Y 70<025>C. >ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS POR SU ACTIVIDAD ANTIBACTERIANA.
ES508723A 1980-03-04 1982-01-14 "un procedimiento para la preparacion de derivados de metoxicefalosporinas". Granted ES508723A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP2611280A JPS56122384A (en) 1980-03-04 1980-03-04 7alpha-methoxycephalosporin derivative, its preparation and antifungal agent comprising it
JP9219980A JPS5718689A (en) 1980-07-08 1980-07-08 7alpha-methoxycephem derivative

Publications (2)

Publication Number Publication Date
ES8300773A1 true ES8300773A1 (es) 1982-11-01
ES508723A0 ES508723A0 (es) 1982-11-01

Family

ID=26363848

Family Applications (2)

Application Number Title Priority Date Filing Date
ES498145A Granted ES498145A0 (es) 1980-03-04 1980-12-24 Un procedimiento para la preparacion de derivados de metoxi-cefalosporinas
ES508723A Granted ES508723A0 (es) 1980-03-04 1982-01-14 "un procedimiento para la preparacion de derivados de metoxicefalosporinas".

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES498145A Granted ES498145A0 (es) 1980-03-04 1980-12-24 Un procedimiento para la preparacion de derivados de metoxi-cefalosporinas

Country Status (17)

Country Link
US (2) US4344944A (es)
KR (1) KR840002162B1 (es)
AT (1) AT373895B (es)
AU (1) AU540042B2 (es)
CA (1) CA1165759A (es)
CH (1) CH643850A5 (es)
DE (1) DE3048657A1 (es)
DK (1) DK548380A (es)
ES (2) ES498145A0 (es)
FR (1) FR2477548A1 (es)
GB (1) GB2070589B (es)
HU (1) HU183276B (es)
IT (1) IT8026965A0 (es)
NL (1) NL8007011A (es)
PH (1) PH17794A (es)
SE (1) SE8009049L (es)
SU (3) SU1095879A3 (es)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5855491A (ja) * 1981-09-29 1983-04-01 Eisai Co Ltd ３−カルバモイルオキシメチルセフエム誘導体およびその製造法
US4546176A (en) * 1982-12-14 1985-10-08 Eisai Co., Ltd. 7-Carboxymethoxyphenylacetamido-3-cephem derivatives and antibacterial preparations containing the same
AU2002334987A1 (en) * 2001-10-15 2003-04-28 The Regents Of The University Of Michigan Systems and methods for the generation of crystalline polymorphs
US20070036950A1 (en) * 2005-08-15 2007-02-15 Royal Brush Manufacturing, Inc. Dry transfer lettering with separable units

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4165429A (en) * 1976-06-28 1979-08-21 Yamanouchi Pharmaceutical Co., Ltd. 7α-METHOXY-CEPHALOSPORANIC ACID DERIVATIVES
US4150224A (en) * 1977-10-04 1979-04-17 Yeda Research And Development Co., Ltd. 7[[(1-Pyrrollyl)7 acetyl]amino]cephalosporin derivatives
US4124762A (en) * 1977-11-07 1978-11-07 Yeda Research And Development Co., Ltd. 7-[(Pyridylthiomethyl)phenyl]acetamido-cephalosporin derivatives
JPS565487A (en) * 1979-06-26 1981-01-20 Eisai Co Ltd Cephalosporin compound, its preparation, and antimicrobial comprising it

Also Published As

Publication number Publication date
GB2070589A (en) 1981-09-09
DE3048657A1 (de) 1981-10-01
KR830004316A (ko) 1983-07-09
FR2477548B1 (es) 1983-06-10
SU1095879A3 (ru) 1984-05-30
DK548380A (da) 1981-09-05
NL8007011A (nl) 1981-10-01
FR2477548A1 (fr) 1981-09-11
HU183276B (en) 1984-04-28
IT8026965A0 (it) 1980-12-24
ES8205809A1 (es) 1982-06-16
AU540042B2 (en) 1984-11-01
SU1105117A3 (ru) 1984-07-23
AT373895B (de) 1984-02-27
KR840002162B1 (ko) 1984-11-24
GB2070589B (en) 1984-06-06
SE8009049L (sv) 1981-09-05
ES508723A0 (es) 1982-11-01
AU6583080A (en) 1981-09-10
CH643850A5 (de) 1984-06-29
ATA630780A (de) 1983-07-15
ES498145A0 (es) 1982-06-16
SU1130569A1 (ru) 1984-12-23
CA1165759A (en) 1984-04-17
US4415567A (en) 1983-11-15
PH17794A (en) 1984-12-13
US4344944A (en) 1982-08-17

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