ES8106500A1 - Procedimiento de preparacion de nuevos derivados de 1-(1-(3,4-dimetoxi-fenil)-3-amino-propil)-6,7-dimetoxi-iso- quinoleina - Google Patents

Procedimiento de preparacion de nuevos derivados de 1-(1-(3,4-dimetoxi-fenil)-3-amino-propil)-6,7-dimetoxi-iso- quinoleina

Info

Publication number
ES8106500A1
ES8106500A1 ES493503A ES493503A ES8106500A1 ES 8106500 A1 ES8106500 A1 ES 8106500A1 ES 493503 A ES493503 A ES 493503A ES 493503 A ES493503 A ES 493503A ES 8106500 A1 ES8106500 A1 ES 8106500A1
Authority
ES
Spain
Prior art keywords
radical
carbon atoms
alkyl
manufacture
composition containing
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES493503A
Other languages
English (en)
Other versions
ES493503A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of ES8106500A1 publication Critical patent/ES8106500A1/es
Publication of ES493503A0 publication Critical patent/ES493503A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C07D217/20—Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

PROCEDIMIENTO DE OBTENCION DE DERIVADOS DE 1-[1-(3,4-DIMETOXI-FENIL)-3-AMINO PROPIL]-6,7-DIMETOXI-ISOQUINOLEINA. CONSISTE EN CONDENSAR EN UN DISOLVENTE POLAR, ENTRE 0 Y 25 GC, 1[1-(3,4-DIMETOXIFENIL)-3-OXO-PROPIL]-6,7-DIMETOXI-ISOQUINOLEINA, CON UN COMPUESTO DE FORMULA GENERAL HNR1R2, REDUCIENDO A CONTINUACION EL COMPUESTO RESULTANTE POR TECNICAS CONVENCIONALES TALES COMO HIDROGENACION O MEDIANTE BOROHIDRURO DE SODIO. EL DISOLVENTE EMPLEADO NORMALMENTE ES ETANOL. R1 REPRESENTA UN ATOMO DE HIDROGENO, O UN GRUPO METILO; R2 ES UN GRUPO ALCOHILO CON 1 A 5 ATOMOS DE CARBORO O UN GRUPO CICLOALCOHILO CON 5 A 7 ATOMOS DE CARBONO.
ES493503A 1979-07-19 1980-07-18 Procedimiento de preparacion de nuevos derivados de 1-(1-(3,4-dimetoxi-fenil)-3-amino-propil)-6,7-dimetoxi-iso- quinoleina Granted ES493503A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7925276 1979-07-19

Publications (2)

Publication Number Publication Date
ES8106500A1 true ES8106500A1 (es) 1981-07-01
ES493503A0 ES493503A0 (es) 1981-07-01

Family

ID=10506637

Family Applications (1)

Application Number Title Priority Date Filing Date
ES493503A Granted ES493503A0 (es) 1979-07-19 1980-07-18 Procedimiento de preparacion de nuevos derivados de 1-(1-(3,4-dimetoxi-fenil)-3-amino-propil)-6,7-dimetoxi-iso- quinoleina

Country Status (28)

Country Link
JP (1) JPS5618964A (es)
AR (1) AR228953A1 (es)
AT (1) AT375649B (es)
AU (1) AU538065B2 (es)
BE (1) BE884242A (es)
CA (1) CA1152998A (es)
CH (1) CH644848A5 (es)
DE (1) DE3027338C2 (es)
DK (1) DK152124C (es)
EG (1) EG14616A (es)
ES (1) ES493503A0 (es)
FI (1) FI77027C (es)
FR (2) FR2461497A1 (es)
GR (1) GR69195B (es)
IE (1) IE50023B1 (es)
IL (1) IL60482A (es)
IN (1) IN154316B (es)
IT (1) IT1237319B (es)
LU (1) LU82608A1 (es)
MA (1) MA18906A1 (es)
MX (1) MX5962E (es)
NL (1) NL8004053A (es)
NO (1) NO155883C (es)
NZ (1) NZ194280A (es)
OA (1) OA06696A (es)
PT (1) PT71578A (es)
SE (1) SE448092B (es)
ZA (1) ZA803993B (es)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10320274A1 (de) * 2003-05-07 2004-12-09 Sennheiser Electronic Gmbh & Co. Kg System zur ortssensitiven Wiedergabe von Audiosignalen

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1400425A (en) * 1971-09-22 1975-07-16 Rolland Sa A Substituted 3-hydroxymethyl-isoquinolines and derivatives
US3966724A (en) * 1974-12-20 1976-06-29 Armour Pharmaceutical Company 1-(α-Aminomethylbenzyl)isoquinoline compounds
IT1143667B (it) * 1977-05-30 1986-10-22 Scharber Per L Ind Farmaceutic Derivato paraverolinico ad azione duratura e procedimento per ottenerlo
IN154317B (es) * 1979-07-19 1984-10-13 Andre Buzas

Also Published As

Publication number Publication date
MX5962E (es) 1984-09-06
DK310180A (da) 1981-01-20
NO155883C (no) 1987-06-17
FR2461702B1 (es) 1983-08-19
DE3027338C2 (de) 1984-08-09
FI77027C (fi) 1989-01-10
IN154316B (es) 1984-10-13
DE3027338A1 (de) 1981-02-19
FR2461702A1 (fr) 1981-02-06
DK152124C (da) 1988-06-20
IE801498L (en) 1981-01-19
CH644848A5 (en) 1984-08-31
DK152124B (da) 1988-02-01
NL8004053A (nl) 1981-01-21
AR228953A1 (es) 1983-05-13
EG14616A (en) 1989-09-30
IT1237319B (it) 1993-05-31
NZ194280A (en) 1982-03-23
AU538065B2 (en) 1984-07-26
IL60482A0 (en) 1980-09-16
FI802118A (fi) 1981-01-20
SE448092B (sv) 1987-01-19
CA1152998A (en) 1983-08-30
AT375649B (de) 1984-08-27
BE884242A (fr) 1980-11-03
ATA371980A (de) 1984-01-15
IT8023536A0 (it) 1980-07-18
GR69195B (es) 1982-05-06
ZA803993B (en) 1981-07-29
MA18906A1 (fr) 1981-04-01
PT71578A (en) 1980-08-01
IE50023B1 (en) 1986-02-05
IL60482A (en) 1984-02-29
FR2461497B1 (es) 1983-07-01
SE8005260L (sv) 1981-01-20
NO155883B (no) 1987-03-09
JPS5618964A (en) 1981-02-23
AU6063080A (en) 1981-01-22
OA06696A (fr) 1982-05-31
FR2461497A1 (fr) 1981-02-06
LU82608A1 (fr) 1980-10-24
FI77027B (fi) 1988-09-30
ES493503A0 (es) 1981-07-01
NO802160L (no) 1981-01-20

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19960603