ES469234A1 - Procedimiento de preparacion de derivados de piridazinona - Google Patents

Procedimiento de preparacion de derivados de piridazinona

Info

Publication number
ES469234A1
ES469234A1 ES469234A ES469234A ES469234A1 ES 469234 A1 ES469234 A1 ES 469234A1 ES 469234 A ES469234 A ES 469234A ES 469234 A ES469234 A ES 469234A ES 469234 A1 ES469234 A1 ES 469234A1
Authority
ES
Spain
Prior art keywords
carbon atoms
anorexigenic
group containing
pyridazinones
phenoxy
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES469234A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Laboratoires Albert Rolland SA
Original Assignee
Laboratoires Albert Rolland SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Laboratoires Albert Rolland SA filed Critical Laboratoires Albert Rolland SA
Publication of ES469234A1 publication Critical patent/ES469234A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/12—Halogen atoms or nitro radicals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/04—Anorexiants; Antiobesity agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/14—Oxygen atoms
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D237/00—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings
    • C07D237/02—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings
    • C07D237/06—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members
    • C07D237/10—Heterocyclic compounds containing 1,2-diazine or hydrogenated 1,2-diazine rings not condensed with other rings having three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D237/14—Oxygen atoms
    • C07D237/16—Two oxygen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Neurosurgery (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Child & Adolescent Psychology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Plural Heterocyclic Compounds (AREA)

Abstract

1.Procedimiento de preparación de derivados de piridazinona de la fórmula I **(Fórmula-01)** en la cual R1 y R2, idénticos o diferentes, representan el átomo de hidrógeno, un átomo de halógeno, un grupo alcohilo de 1 a 3 átomos de carbono, un grupo alcoxi de 1 a 3 átomos de carbono o un grupo trifluorometilo, y R3 representa un grupo alcohilo de 1 a 4 átomos de carbono mono o polihidroxilado, pudiendo estas funciones alcoholes estar esterificadas por un ácido benzoico sustituido o no, procedimiento que consiste en reemplazar en un compuesto de la fórmula II **(Fórmula-02)** en la cual R1 y R2 tienen los mismos significados que anteriormente, el átomo de hidrógeno en posición 2 existente en el ciclo de piridazinona, por un sustituyente R3 tal como se ha definido anteriormente.
ES469234A 1977-04-28 1978-04-27 Procedimiento de preparacion de derivados de piridazinona Expired ES469234A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7712888A FR2388799A1 (fr) 1977-04-28 1977-04-28 Derives de pyridazinone, leur procede de preparation et leur application comme medicaments

Publications (1)

Publication Number Publication Date
ES469234A1 true ES469234A1 (es) 1980-05-16

Family

ID=9190051

Family Applications (2)

Application Number Title Priority Date Filing Date
ES469234A Expired ES469234A1 (es) 1977-04-28 1978-04-27 Procedimiento de preparacion de derivados de piridazinona
ES476449A Expired ES476449A1 (es) 1977-04-28 1978-11-20 Procedimiento de preparacion de derivados de piridazinona.

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES476449A Expired ES476449A1 (es) 1977-04-28 1978-11-20 Procedimiento de preparacion de derivados de piridazinona.

Country Status (18)

Country Link
US (1) US4188388A (es)
JP (1) JPS53135993A (es)
AU (1) AU3552678A (es)
BE (1) BE866492A (es)
DD (1) DD135488A5 (es)
DE (1) DE2817649A1 (es)
ES (2) ES469234A1 (es)
FR (1) FR2388799A1 (es)
GB (1) GB1584119A (es)
IE (1) IE46730B1 (es)
IL (1) IL54547A0 (es)
IT (1) IT1111174B (es)
LU (1) LU79520A1 (es)
NL (1) NL7804374A (es)
NZ (1) NZ187085A (es)
PL (1) PL112610B1 (es)
PT (1) PT67958B (es)
ZA (1) ZA782209B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2510997A1 (fr) * 1981-08-10 1983-02-11 Sanofi Sa Nouveaux derives de la methyl-4 phenyl-6 pyridazine, procede pour leur preparation et medicaments actifs sur le systeme nerveux central en contenant
DE60234057D1 (de) 2001-07-25 2009-11-26 Raptor Pharmaceutical Inc Zusammensetzungen und verfahren zur modulation des transports durch die blut-hirn-schranke
EP2392258B1 (en) 2005-04-28 2014-10-08 Proteus Digital Health, Inc. Pharma-informatics system
US8795627B2 (en) 2007-03-21 2014-08-05 Raptor Pharmaceuticals Inc. Treatment of liver disorders by administration of RAP conjugates
US8076334B2 (en) * 2007-09-20 2011-12-13 Hoffmann-La Roche Inc. Prodrugs of thyroid hormone analogs
AU2010216512B2 (en) 2009-02-20 2016-06-30 2-Bbb Medicines B.V. Glutathione-based drug delivery system
WO2010129819A2 (en) 2009-05-06 2010-11-11 Laboratory Skin Care, Inc. Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
PL227639B1 (pl) 2014-05-28 2018-01-31 Werner Kenkel Spólka Z Ograniczona Odpowiedzialnoscia Platforma ekspozycyjna

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1913265A1 (de) * 1969-03-15 1970-10-01 Basf Ag Verfahren zur Herstellung von 2-Alkylpyridazoniumverbindungen

Also Published As

Publication number Publication date
IL54547A0 (en) 1978-07-31
ES476449A1 (es) 1979-05-16
IE46730B1 (en) 1983-09-07
DD135488A5 (de) 1979-05-09
PT67958B (fr) 1979-11-14
AU3552678A (en) 1979-11-01
DE2817649A1 (de) 1978-11-09
BE866492A (fr) 1978-10-27
PL206456A1 (pl) 1979-04-23
PL112610B1 (en) 1980-10-31
IT7822754A0 (it) 1978-04-27
PT67958A (fr) 1978-05-01
FR2388799A1 (fr) 1978-11-24
NL7804374A (nl) 1978-10-31
US4188388A (en) 1980-02-12
IE780778L (en) 1978-10-28
ZA782209B (en) 1979-04-25
FR2388799B1 (es) 1980-06-27
LU79520A1 (fr) 1978-11-28
IT1111174B (it) 1986-01-13
GB1584119A (en) 1981-02-04
NZ187085A (en) 1979-12-11
JPS53135993A (en) 1978-11-28

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