IE801498L - Isoquinoline derivatives - Google Patents

Isoquinoline derivatives

Info

Publication number
IE801498L
IE801498L IE801498A IE149880A IE801498L IE 801498 L IE801498 L IE 801498L IE 801498 A IE801498 A IE 801498A IE 149880 A IE149880 A IE 149880A IE 801498 L IE801498 L IE 801498L
Authority
IE
Ireland
Prior art keywords
radical
carbon atoms
alkyl
optionally substituted
cycloalkyl radical
Prior art date
Application number
IE801498A
Other versions
IE50023B1 (en
Original Assignee
Mr Andre Buzas
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Mr Andre Buzas filed Critical Mr Andre Buzas
Publication of IE801498L publication Critical patent/IE801498L/en
Publication of IE50023B1 publication Critical patent/IE50023B1/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18Aralkyl radicals
    • C07D217/20Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

The disclosure is made of 1-[1-(3,4-dimethoxyphenyl)-3-aminopropyl]-6,7-dimethoxyisoquinoline, corresponding to the general formula (I): <IMAGE> in which - R1 represents a hydrogen atom or a methyl radical and - R2 represents an alkyl radical comprising 1 to 5 carbon atoms or a cycloalkyl radical comprising 5 to 7 carbon atoms, the alkyl or cycloalkyl radical being optionally substituted by a hydroxyl, phenyl or phenoxy radical and the cycloalkyl radical being optionally substituted by an alkyl radical comprising 1 to 5 carbon atoms, the therapeutically acceptable salts thereof and a process for the preparation thereof. The compounds can be used as active components in therapeutic compositions intended for the cardiovascular field. [FR2461497A1]
IE1498/80A 1979-07-19 1980-07-18 Isoquinoline derivatives IE50023B1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7925276 1979-07-19

Publications (2)

Publication Number Publication Date
IE801498L true IE801498L (en) 1981-01-19
IE50023B1 IE50023B1 (en) 1986-02-05

Family

ID=10506637

Family Applications (1)

Application Number Title Priority Date Filing Date
IE1498/80A IE50023B1 (en) 1979-07-19 1980-07-18 Isoquinoline derivatives

Country Status (28)

Country Link
JP (1) JPS5618964A (en)
AR (1) AR228953A1 (en)
AT (1) AT375649B (en)
AU (1) AU538065B2 (en)
BE (1) BE884242A (en)
CA (1) CA1152998A (en)
CH (1) CH644848A5 (en)
DE (1) DE3027338C2 (en)
DK (1) DK152124C (en)
EG (1) EG14616A (en)
ES (1) ES493503A0 (en)
FI (1) FI77027C (en)
FR (2) FR2461497A1 (en)
GR (1) GR69195B (en)
IE (1) IE50023B1 (en)
IL (1) IL60482A (en)
IN (1) IN154316B (en)
IT (1) IT1237319B (en)
LU (1) LU82608A1 (en)
MA (1) MA18906A1 (en)
MX (1) MX5962E (en)
NL (1) NL8004053A (en)
NO (1) NO155883C (en)
NZ (1) NZ194280A (en)
OA (1) OA06696A (en)
PT (1) PT71578A (en)
SE (1) SE448092B (en)
ZA (1) ZA803993B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10320274A1 (en) * 2003-05-07 2004-12-09 Sennheiser Electronic Gmbh & Co. Kg System for the location-sensitive reproduction of audio signals

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1400425A (en) * 1971-09-22 1975-07-16 Rolland Sa A Substituted 3-hydroxymethyl-isoquinolines and derivatives
US3966724A (en) * 1974-12-20 1976-06-29 Armour Pharmaceutical Company 1-(α-Aminomethylbenzyl)isoquinoline compounds
IT1143667B (en) * 1977-05-30 1986-10-22 Scharber Per L Ind Farmaceutic PARAVEROLINIC DERIVATIVE WITH A DURABLE ACTION AND PROCEDURE TO OBTAIN IT
IN154317B (en) * 1979-07-19 1984-10-13 Andre Buzas

Also Published As

Publication number Publication date
MX5962E (en) 1984-09-06
DK310180A (en) 1981-01-20
NO155883C (en) 1987-06-17
FR2461702B1 (en) 1983-08-19
DE3027338C2 (en) 1984-08-09
FI77027C (en) 1989-01-10
IN154316B (en) 1984-10-13
DE3027338A1 (en) 1981-02-19
FR2461702A1 (en) 1981-02-06
DK152124C (en) 1988-06-20
ES8106500A1 (en) 1981-07-01
CH644848A5 (en) 1984-08-31
DK152124B (en) 1988-02-01
NL8004053A (en) 1981-01-21
AR228953A1 (en) 1983-05-13
EG14616A (en) 1989-09-30
IT1237319B (en) 1993-05-31
NZ194280A (en) 1982-03-23
AU538065B2 (en) 1984-07-26
IL60482A0 (en) 1980-09-16
FI802118A (en) 1981-01-20
SE448092B (en) 1987-01-19
CA1152998A (en) 1983-08-30
AT375649B (en) 1984-08-27
BE884242A (en) 1980-11-03
ATA371980A (en) 1984-01-15
IT8023536A0 (en) 1980-07-18
GR69195B (en) 1982-05-06
ZA803993B (en) 1981-07-29
MA18906A1 (en) 1981-04-01
PT71578A (en) 1980-08-01
IE50023B1 (en) 1986-02-05
IL60482A (en) 1984-02-29
FR2461497B1 (en) 1983-07-01
SE8005260L (en) 1981-01-20
NO155883B (en) 1987-03-09
JPS5618964A (en) 1981-02-23
AU6063080A (en) 1981-01-22
OA06696A (en) 1982-05-31
FR2461497A1 (en) 1981-02-06
LU82608A1 (en) 1980-10-24
FI77027B (en) 1988-09-30
ES493503A0 (en) 1981-07-01
NO802160L (en) 1981-01-20

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