SE8005260L - NEW ISOQINOLINE DERIVATIVES AND PREPARATION OF THEREOF - Google Patents

NEW ISOQINOLINE DERIVATIVES AND PREPARATION OF THEREOF

Info

Publication number
SE8005260L
SE8005260L SE8005260A SE8005260A SE8005260L SE 8005260 L SE8005260 L SE 8005260L SE 8005260 A SE8005260 A SE 8005260A SE 8005260 A SE8005260 A SE 8005260A SE 8005260 L SE8005260 L SE 8005260L
Authority
SE
Sweden
Prior art keywords
new
carbon atoms
preparation
isoqinoline
derivatives
Prior art date
Application number
SE8005260A
Other languages
Swedish (sv)
Other versions
SE448092B (en
Inventor
A Buzas
G Lavielle
Original Assignee
Buzas Andre
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Buzas Andre filed Critical Buzas Andre
Publication of SE8005260L publication Critical patent/SE8005260L/en
Publication of SE448092B publication Critical patent/SE448092B/en

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D217/00Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18Aralkyl radicals
    • C07D217/20Aralkyl radicals with oxygen atoms directly attached to the aromatic ring of said aralkyl radical, e.g. papaverine
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/06Antiarrhythmics

Landscapes

  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Cardiology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Saccharide Compounds (AREA)

Abstract

The present invention relates to new 1-¢1-(3,4-dimethoxy-phenyl) -3-amino-propyl!-6,7-dimethoxy-isoquinolines having the general formula I : <IMG> I in which R1 represents a hydrogen atom or a methyl group ; and R2 represents an alkyl group having from 1 to 5 carbon atoms or a cycloalkyl group having from 5 to 7 carbon atoms, the alkyl or cycloalkyl group optionally being substituted by a hydroxy, phenyl or phenoxy group and the cycloalkyl group optionally being substituted by an alkyl group having from 1 to 5 carbon atoms, therapeutically acceptable salts thereof and a process preparation of the same. These compounds are useful in the cardiac and vascular fields.
SE8005260A 1979-07-19 1980-07-18 NEW ISOQINOLINE DERIVATIVES, PROCEDURES FOR PREPARING THEREOF AND THERAPEUTIC COMPOSITIONS CONTAINING THEM SE448092B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7925276 1979-07-19

Publications (2)

Publication Number Publication Date
SE8005260L true SE8005260L (en) 1981-01-20
SE448092B SE448092B (en) 1987-01-19

Family

ID=10506637

Family Applications (1)

Application Number Title Priority Date Filing Date
SE8005260A SE448092B (en) 1979-07-19 1980-07-18 NEW ISOQINOLINE DERIVATIVES, PROCEDURES FOR PREPARING THEREOF AND THERAPEUTIC COMPOSITIONS CONTAINING THEM

Country Status (28)

Country Link
JP (1) JPS5618964A (en)
AR (1) AR228953A1 (en)
AT (1) AT375649B (en)
AU (1) AU538065B2 (en)
BE (1) BE884242A (en)
CA (1) CA1152998A (en)
CH (1) CH644848A5 (en)
DE (1) DE3027338C2 (en)
DK (1) DK152124C (en)
EG (1) EG14616A (en)
ES (1) ES493503A0 (en)
FI (1) FI77027C (en)
FR (2) FR2461702A1 (en)
GR (1) GR69195B (en)
IE (1) IE50023B1 (en)
IL (1) IL60482A (en)
IN (1) IN154316B (en)
IT (1) IT1237319B (en)
LU (1) LU82608A1 (en)
MA (1) MA18906A1 (en)
MX (1) MX5962E (en)
NL (1) NL8004053A (en)
NO (1) NO155883C (en)
NZ (1) NZ194280A (en)
OA (1) OA06696A (en)
PT (1) PT71578A (en)
SE (1) SE448092B (en)
ZA (1) ZA803993B (en)

Families Citing this family (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE10320274A1 (en) * 2003-05-07 2004-12-09 Sennheiser Electronic Gmbh & Co. Kg System for the location-sensitive reproduction of audio signals

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1400425A (en) * 1971-09-22 1975-07-16 Rolland Sa A Substituted 3-hydroxymethyl-isoquinolines and derivatives
US3966724A (en) * 1974-12-20 1976-06-29 Armour Pharmaceutical Company 1-(α-Aminomethylbenzyl)isoquinoline compounds
IT1143667B (en) * 1977-05-30 1986-10-22 Scharber Per L Ind Farmaceutic PARAVEROLINIC DERIVATIVE WITH A DURABLE ACTION AND PROCEDURE TO OBTAIN IT
IN154317B (en) * 1979-07-19 1984-10-13 Andre Buzas

Also Published As

Publication number Publication date
MX5962E (en) 1984-09-06
IL60482A0 (en) 1980-09-16
FR2461497A1 (en) 1981-02-06
FI77027C (en) 1989-01-10
FI802118A (en) 1981-01-20
FI77027B (en) 1988-09-30
ES8106500A1 (en) 1981-07-01
AU6063080A (en) 1981-01-22
JPS5618964A (en) 1981-02-23
CA1152998A (en) 1983-08-30
DK310180A (en) 1981-01-20
AR228953A1 (en) 1983-05-13
NO155883C (en) 1987-06-17
NZ194280A (en) 1982-03-23
AU538065B2 (en) 1984-07-26
NO155883B (en) 1987-03-09
FR2461497B1 (en) 1983-07-01
ATA371980A (en) 1984-01-15
PT71578A (en) 1980-08-01
IN154316B (en) 1984-10-13
DE3027338A1 (en) 1981-02-19
ES493503A0 (en) 1981-07-01
LU82608A1 (en) 1980-10-24
NL8004053A (en) 1981-01-21
GR69195B (en) 1982-05-06
DE3027338C2 (en) 1984-08-09
IE801498L (en) 1981-01-19
IL60482A (en) 1984-02-29
EG14616A (en) 1989-09-30
SE448092B (en) 1987-01-19
FR2461702A1 (en) 1981-02-06
IT8023536A0 (en) 1980-07-18
AT375649B (en) 1984-08-27
NO802160L (en) 1981-01-20
FR2461702B1 (en) 1983-08-19
ZA803993B (en) 1981-07-29
DK152124B (en) 1988-02-01
CH644848A5 (en) 1984-08-31
DK152124C (en) 1988-06-20
MA18906A1 (en) 1981-04-01
OA06696A (en) 1982-05-31
IE50023B1 (en) 1986-02-05
IT1237319B (en) 1993-05-31
BE884242A (en) 1980-11-03

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