ES524816A0 - Procedimiento para la produccion de polipetidos mediante levadura. - Google Patents

Procedimiento para la produccion de polipetidos mediante levadura.

Info

Publication number
ES524816A0
ES524816A0 ES524816A ES524816A ES524816A0 ES 524816 A0 ES524816 A0 ES 524816A0 ES 524816 A ES524816 A ES 524816A ES 524816 A ES524816 A ES 524816A ES 524816 A0 ES524816 A0 ES 524816A0
Authority
ES
Spain
Prior art keywords
yeast
promoter
production
polypethydes
procedure
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES524816A
Other languages
English (en)
Other versions
ES8505724A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Novartis AG
Original Assignee
Ciba Geigy AG
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838315145A external-priority patent/GB8315145D0/en
Application filed by Ciba Geigy AG filed Critical Ciba Geigy AG
Publication of ES524816A0 publication Critical patent/ES524816A0/es
Publication of ES8505724A1 publication Critical patent/ES8505724A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/005—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from viruses
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/555—Interferons [IFN]
    • C07K14/56—IFN-alpha
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09—Recombinant DNA-technology
    • C12N15/63—Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79—Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/80—Vectors or expression systems specially adapted for eukaryotic hosts for fungi
    • C12N15/81—Vectors or expression systems specially adapted for eukaryotic hosts for fungi for yeasts
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/036—Fusion polypeptide containing a localisation/targetting motif targeting to the medium outside of the cell, e.g. type III secretion
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/70—Fusion polypeptide containing domain for protein-protein interaction
    • C07K2319/74—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor
    • C07K2319/75—Fusion polypeptide containing domain for protein-protein interaction containing a fusion for binding to a cell surface receptor containing a fusion for activation of a cell surface receptor, e.g. thrombopoeitin, NPY and other peptide hormones
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2730/00—Reverse transcribing DNA viruses
    • C12N2730/00011—Details
    • C12N2730/10011—Hepadnaviridae
    • C12N2730/10111—Orthohepadnavirus, e.g. hepatitis B virus
    • C12N2730/10122—New viral proteins or individual genes, new structural or functional aspects of known viral proteins or genes
ES524816A 1982-08-09 1983-08-08 Procedimiento para la produccion de polipetidos mediante levadura. Expired ES8505724A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB8222883 1982-08-09
GB8237026 1982-12-31
GB838315145A GB8315145D0 (en) 1982-08-09 1983-06-02 Yeast hybrid vectors

Publications (2)

Publication Number Publication Date
ES524816A0 true ES524816A0 (es) 1985-06-01
ES8505724A1 ES8505724A1 (es) 1985-06-01

Family

ID=27261693

Family Applications (3)

Application Number Title Priority Date Filing Date
ES524816A Expired ES8505724A1 (es) 1982-08-09 1983-08-08 Procedimiento para la produccion de polipetidos mediante levadura.
ES540880A Expired ES8607391A1 (es) 1982-08-09 1985-03-01 Procedimiento para producir un fragmento de dna que compren-de un promotor de fosfatasa acida de levadura
ES540881A Expired ES8607026A1 (es) 1982-08-09 1985-03-01 Procedimiento para producir vectores hibridos de levadura

Family Applications After (2)

Application Number Title Priority Date Filing Date
ES540880A Expired ES8607391A1 (es) 1982-08-09 1985-03-01 Procedimiento para producir un fragmento de dna que compren-de un promotor de fosfatasa acida de levadura
ES540881A Expired ES8607026A1 (es) 1982-08-09 1985-03-01 Procedimiento para producir vectores hibridos de levadura

Country Status (20)

Country Link
EP (1) EP0100561B1 (es)
JP (2) JPH0653073B2 (es)
AT (1) ATE43636T1 (es)
AU (1) AU566348B2 (es)
CA (1) CA1341381C (es)
CY (1) CY1451A (es)
DD (1) DD218118A5 (es)
DE (1) DE3379960D1 (es)
DK (1) DK174905B1 (es)
ES (3) ES8505724A1 (es)
FI (1) FI80720C (es)
GB (1) GB2125047B (es)
GR (1) GR78924B (es)
HK (1) HK90688A (es)
HU (1) HU204095B (es)
IE (1) IE55598B1 (es)
NO (1) NO172548C (es)
NZ (1) NZ205178A (es)
PH (1) PH25617A (es)
PT (1) PT77167B (es)

Families Citing this family (42)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2125047B (en) * 1982-08-09 1986-02-19 Ciba Geigy Ag Yeast hybrid vectors and their use for the production of polypeptides
JPS5936699A (ja) * 1982-08-20 1984-02-28 Chemo Sero Therapeut Res Inst シヤトルベクタ−
JPS5931799A (ja) * 1982-08-16 1984-02-20 Science & Tech Agency Ｂ型肝炎ウイルス遺伝子を組込んだ組換えプラスミド
DE3381566D1 (de) * 1982-08-16 1990-06-21 Agency Science & Tech Hepatitis-b-virus-gen enthaltendes rekombinantes plasmid, mit diesem rekombinanten plasmid transformierte hefe und herstellung von hepatitis-b-virus-oberflaechenantigen.
AU584580B2 (en) * 1982-09-08 1989-06-01 Smith Kline - Rit Hepatitis B virus vaccine
JPS5974988A (ja) * 1982-10-20 1984-04-27 Suntory Ltd 酵母の誘導発現型プラスミドベクタ−およびその利用方法
ZA843275B (en) * 1983-05-05 1984-12-24 Hoffmann La Roche Novel vectors for interferon expression
GR80966B (en) * 1983-11-21 1985-03-15 Ciba Geigy Ag Synthesis of fibrinolytic agents by yeast
JPS60248181A (ja) * 1984-05-23 1985-12-07 Shiseido Co Ltd 酵母発現ベクタ−
AU600885B2 (en) * 1984-05-25 1990-08-30 Zymogenetics Inc. Stable DNA constructs
US5723292A (en) * 1984-05-25 1998-03-03 Zymogenetics, Inc. Stable DNA constructs
GB8415186D0 (en) * 1984-06-14 1984-07-18 Ciba Geigy Ag Polypeptides
EP0188555A4 (en) * 1984-07-09 1988-04-18 Integrated Genetics Inc YEAST CLONING VEHICLE.
JPS61502795A (ja) * 1984-07-09 1986-12-04 レモント，ジェフリ−・エフ 酵母クロ−ニング　ビ−クル
EP0192679A4 (en) * 1984-07-31 1988-04-26 Integrated Genetics Inc YEAST CLONING VECTORS.
JPS61103895A (ja) * 1984-10-26 1986-05-22 Green Cross Corp:The ＨＢｓＡｇの精製方法
US5336609A (en) * 1984-12-06 1994-08-09 Labofina, S.A. Transformed yeasts for producing lysozyme, plasmids used for this transformation, method of producing lysozyme
DE3685044D1 (de) * 1985-02-01 1992-06-04 Ici Plc Analoge interferon-polypeptide, verfahren zu deren herstellung und diese enthaltende pharmazeutische zusammensetzungen.
GB8521496D0 (en) * 1985-08-29 1985-10-02 Ciba Geigy Ag Repressible yeast promoters
DE3675724D1 (de) * 1985-09-18 1991-01-03 Green Cross Corp Hefe-promotor und verfahren zur herstellung von heterologen proteinen.
JPS62151183A (ja) * 1985-09-18 1987-07-06 Green Cross Corp:The 酵母プロモ−タ−及び異種蛋白質の製造方法
GB8530631D0 (en) 1985-12-12 1986-01-22 Ciba Geigy Ag Thrombin inhibitors
GB2188049B (en) * 1986-03-15 1990-09-05 Ciba Geigy Ag Insecticidal proteinaceous substance
EP0240224A3 (en) * 1986-03-31 1989-02-01 Interferon Sciences, Inc. An alpha interferon analogue
US4857467A (en) * 1986-07-23 1989-08-15 Phillips Petroleum Company Carbon and energy source markers for transformation of strains of the genes Pichia
EP0263072B1 (en) 1986-10-03 1994-03-23 Ciba-Geigy Ag Novel lymphokine related peptides
US5013652A (en) * 1986-10-14 1991-05-07 Genex Corporation Composite yeast vectors
US5180667A (en) * 1988-03-07 1993-01-19 Ciba-Geigy Corporation Genes encoding eglin C mutants
ES2063161T3 (es) * 1988-03-07 1995-01-01 Ciba Geigy Ag Proteinas modificadas.
DE68928124T2 (de) 1988-09-02 1997-10-16 Univ Rockefeller Makrophagenabgeleiteter entzündungsmediator(mip-2)
JPH02145193A (ja) * 1988-11-19 1990-06-04 Lotte Confectionery Co Ltd 遺伝子の組換えによる酵母でのヒト・アルファ・インターフェロンの製造方法
AU648214B2 (en) * 1991-12-31 1994-04-14 Lucky Limited Recombinant gene coding for human alpha interferon and expression vector thereof, etc.
DE69434492T2 (de) 1993-03-10 2006-07-13 Smithkline Beecham Corp. Phosphodiesterase des menschlichen gehirns
US6500645B1 (en) 1994-06-17 2002-12-31 Novo Nordisk A/S N-terminally extended proteins expressed in yeast
CA2498017C (en) 2002-09-13 2016-06-14 Cornell Research Foundation, Inc. Using mutations to improve aspergillus phytases
DE102005030552B4 (de) * 2005-06-22 2009-05-28 Eucodis Bioscience Selektion von Phosphatase-Aktivität
CN102059495A (zh) * 2010-11-06 2011-05-18 中国长江航运集团宜昌船厂 一种船体框架胎模及加工方法
ES2627117T3 (es) 2010-12-09 2017-07-26 Institut Pasteur Método basado en MGMT para obtener un rendimiento elevado de expresión de proteínas recombinantes
EP2768950B1 (en) 2011-10-20 2018-03-07 University of Iowa Research Foundation N-demethyase genes and uses thereof
AU2012350229B2 (en) 2011-12-09 2018-03-22 Institut Pasteur Multiplex immuno screening assay
WO2013187957A1 (en) 2012-06-15 2013-12-19 University Of Iowa Research Foundation Caffeine responsive promoters and regulatory genes
WO2022049409A1 (en) 2020-09-02 2022-03-10 Sia Terragen Express diagnosticum for sars-cov-2

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2458585A1 (fr) * 1979-06-07 1981-01-02 Pasteur Institut Procede de production de proteines par expression des genes correspondants dans des micro-organismes et vecteurs susceptibles d'etre mis en oeuvre dans de tels procedes
WO1981002425A1 (en) * 1980-02-25 1981-09-03 R Axel The use of eucaryotic promoter sequences in the production of proteinaceous materials
IL63270A0 (en) * 1980-08-05 1981-10-30 Univ Leland Stanford Junior Eukaryotic autonomously replicating segment
IL63035A (en) * 1980-09-09 1985-05-31 Univ California Dnas capable of replication and stable mitotic maintenance in a host eukaryote,their preparation and eukaryotic cells comprising them
NZ199722A (en) * 1981-02-25 1985-12-13 Genentech Inc Dna transfer vector for expression of exogenous polypeptide in yeast;transformed yeast strain
AU560472B2 (en) * 1981-08-25 1987-04-09 Celltech Limited Yeast expression vectors
NZ201705A (en) * 1981-08-31 1986-03-14 Genentech Inc Recombinant dna method for production of hepatitis b surface antigen in yeast
GB2125047B (en) * 1982-08-09 1986-02-19 Ciba Geigy Ag Yeast hybrid vectors and their use for the production of polypeptides
JPS5931799A (ja) * 1982-08-16 1984-02-20 Science & Tech Agency Ｂ型肝炎ウイルス遺伝子を組込んだ組換えプラスミド

Also Published As

Publication number Publication date
JPH0653073B2 (ja) 1994-07-20
HK90688A (en) 1988-11-18
AU1768283A (en) 1984-02-16
DD218118A5 (de) 1985-01-30
NO172548C (no) 1993-08-04
GR78924B (es) 1984-10-02
IE55598B1 (en) 1990-11-21
DK361483A (da) 1984-02-10
FI832825A0 (fi) 1983-08-05
CY1451A (en) 1989-03-10
ES540881A0 (es) 1986-05-16
GB2125047B (en) 1986-02-19
NO172548B (no) 1993-04-26
DE3379960D1 (en) 1989-07-06
ES8505724A1 (es) 1985-06-01
DK361483D0 (da) 1983-08-08
ES8607026A1 (es) 1986-05-16
FI80720C (fi) 1990-07-10
PH25617A (en) 1991-08-08
CA1341381C (en) 2002-08-06
EP0100561A1 (en) 1984-02-15
ES8607391A1 (es) 1986-05-16
JPH0515379A (ja) 1993-01-26
FI80720B (fi) 1990-03-30
JPH0813277B2 (ja) 1996-02-14
NZ205178A (en) 1986-09-10
HU204095B (en) 1991-11-28
GB2125047A (en) 1984-02-29
JPS5948082A (ja) 1984-03-19
PT77167B (en) 1986-03-20
ATE43636T1 (de) 1989-06-15
NO832848L (no) 1984-02-10
DK174905B1 (da) 2004-02-16
FI832825A (fi) 1984-02-10
IE831860L (en) 1984-02-09
ES540880A0 (es) 1986-05-16
GB8319099D0 (en) 1983-08-17
PT77167A (en) 1983-09-01
EP0100561B1 (en) 1989-05-31
AU566348B2 (en) 1987-10-15

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Legal Events

Date Code Title Description
PC1A Transfer granted
FD1A Patent lapsed

Effective date: 20050309