ES516611A0 - "un procedimiento para la preparacion de monohidrato de dipropionato de beclometasona micronizado". - Google Patents

"un procedimiento para la preparacion de monohidrato de dipropionato de beclometasona micronizado".

Info

Publication number
ES516611A0
ES516611A0 ES516611A ES516611A ES516611A0 ES 516611 A0 ES516611 A0 ES 516611A0 ES 516611 A ES516611 A ES 516611A ES 516611 A ES516611 A ES 516611A ES 516611 A0 ES516611 A0 ES 516611A0
Authority
ES
Spain
Prior art keywords
micronized
procedure
preparation
beclometasone dipropionate
dipropionate monohydrate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES516611A
Other languages
English (en)
Spanish (es)
Other versions
ES8404374A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Glaxo Group Ltd
Original Assignee
Glaxo Group Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Glaxo Group Ltd filed Critical Glaxo Group Ltd
Publication of ES8404374A1 publication Critical patent/ES8404374A1/es
Publication of ES516611A0 publication Critical patent/ES516611A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/007—Pulmonary tract; Aromatherapy
    • A61K9/0073—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy
    • A61K9/0075—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a dry powder inhaler [DPI], e.g. comprising micronized drug mixed with lactose carrier particles
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/56—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids
    • A61K31/57—Compounds containing cyclopenta[a]hydrophenanthrene ring systems; Derivatives thereof, e.g. steroids substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane or progesterone
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
    • A61K9/141—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers
    • A61K9/145—Intimate drug-carrier mixtures characterised by the carrier, e.g. ordered mixtures, adsorbates, solid solutions, eutectica, co-dried, co-solubilised, co-kneaded, co-milled, co-ground products, co-precipitates, co-evaporates, co-extrudates, co-melts; Drug nanoparticles with adsorbed surface modifiers with organic compounds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J5/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond
    • C07J5/0046—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa
    • C07J5/0061—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16
    • C07J5/0069—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group
    • C07J5/0076—Normal steroids containing carbon, hydrogen, halogen or oxygen, substituted in position 17 beta by a chain of two carbon atoms, e.g. pregnane and substituted in position 21 by only one singly bound oxygen atom, i.e. only one oxygen bound to position 21 by a single bond substituted in position 17 alfa substituted in position 16 by a saturated or unsaturated hydrocarbon group by an alkyl group

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Public Health (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Epidemiology (AREA)
  • Pulmonology (AREA)
  • Otolaryngology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Steroid Compounds (AREA)
ES516611A 1981-10-19 1982-10-18 "un procedimiento para la preparacion de monohidrato de dipropionato de beclometasona micronizado". Granted ES516611A0 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB8131425 1981-10-19

Publications (2)

Publication Number Publication Date
ES8404374A1 ES8404374A1 (es) 1984-05-01
ES516611A0 true ES516611A0 (es) 1984-05-01

Family

ID=10525238

Family Applications (1)

Application Number Title Priority Date Filing Date
ES516611A Granted ES516611A0 (es) 1981-10-19 1982-10-18 "un procedimiento para la preparacion de monohidrato de dipropionato de beclometasona micronizado".

Country Status (22)

Country Link
US (1) US4866051A (enExample)
JP (1) JPS5890599A (enExample)
KR (1) KR890000664B1 (enExample)
AU (1) AU551471B2 (enExample)
BE (1) BE894725A (enExample)
CA (1) CA1189853A (enExample)
CH (1) CH652134A5 (enExample)
DE (1) DE3238569A1 (enExample)
DK (1) DK168389B1 (enExample)
DO (1) DOP1990004774A (enExample)
ES (1) ES516611A0 (enExample)
FI (1) FI73128C (enExample)
FR (1) FR2514769B1 (enExample)
HK (1) HK100989A (enExample)
IE (1) IE54170B1 (enExample)
IT (1) IT1196553B (enExample)
MY (1) MY8700910A (enExample)
NL (1) NL8204013A (enExample)
NZ (1) NZ202212A (enExample)
PT (1) PT75692A (enExample)
SE (1) SE454356B (enExample)
ZA (1) ZA827601B (enExample)

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US6565885B1 (en) 1997-09-29 2003-05-20 Inhale Therapeutic Systems, Inc. Methods of spray drying pharmaceutical compositions
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JP4713798B2 (ja) * 1999-06-29 2011-06-29 マンカインド コーポレイション ペプチドおよびタンパク質の薬学的因子の精製および安定化
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JP5167133B2 (ja) 2005-09-14 2013-03-21 マンカインド コーポレイション 結晶性微粒子表面に対する活性薬剤の親和性の増大に基づく薬物処方の方法
US8084420B2 (en) * 2005-09-29 2011-12-27 Biodel Inc. Rapid acting and long acting insulin combination formulations
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Also Published As

Publication number Publication date
PT75692A (en) 1982-11-01
KR890000664B1 (ko) 1989-03-22
AU8946082A (en) 1984-05-03
SE454356B (sv) 1988-04-25
FI73128C (fi) 1987-09-10
IE54170B1 (en) 1989-07-05
FI73128B (fi) 1987-05-29
NZ202212A (en) 1986-01-24
DE3238569A1 (de) 1983-05-05
KR840002007A (ko) 1984-06-11
AU551471B2 (en) 1986-05-01
US4866051A (en) 1989-09-12
DOP1990004774A (es) 1996-02-02
IT8249294A1 (it) 1984-04-18
FI823561A0 (fi) 1982-10-18
DK461182A (da) 1983-04-20
ES8404374A1 (es) 1984-05-01
IT1196553B (it) 1988-11-16
SE8205904L (sv) 1983-04-20
CA1189853A (en) 1985-07-02
JPS5890599A (ja) 1983-05-30
ZA827601B (en) 1983-09-28
HK100989A (en) 1989-12-29
SE8205904D0 (sv) 1982-10-18
MY8700910A (en) 1987-12-31
CH652134A5 (de) 1985-10-31
IT8249294A0 (it) 1982-10-18
NL8204013A (nl) 1983-05-16
FI823561L (fi) 1983-04-20
FR2514769A1 (fr) 1983-04-22
IE822514L (en) 1983-04-19
JPH0424358B2 (enExample) 1992-04-24
DE3238569C2 (enExample) 1991-01-31
BE894725A (fr) 1983-04-18
FR2514769B1 (fr) 1985-08-30
DK168389B1 (da) 1994-03-21

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 20040203