ES502644A0 - Procedimiento de obtencion de nuevos derivados de la vin- blastina - Google Patents

Procedimiento de obtencion de nuevos derivados de la vin- blastina

Info

Publication number
ES502644A0
ES502644A0 ES502644A ES502644A ES502644A0 ES 502644 A0 ES502644 A0 ES 502644A0 ES 502644 A ES502644 A ES 502644A ES 502644 A ES502644 A ES 502644A ES 502644 A0 ES502644 A0 ES 502644A0
Authority
ES
Spain
Prior art keywords
derivatives
blastin
procedure
obtaining new
new vin
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES502644A
Other languages
English (en)
Spanish (es)
Other versions
ES8203385A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Ajinomoto Omnichem NV SA
Original Assignee
Omnichem SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from LU82514A external-priority patent/LU82514A1/fr
Priority claimed from LU83034A external-priority patent/LU83034A1/fr
Application filed by Omnichem SA filed Critical Omnichem SA
Publication of ES8203385A1 publication Critical patent/ES8203385A1/es
Publication of ES502644A0 publication Critical patent/ES502644A0/es
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D519/00—Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/04—Dimeric indole alkaloids, e.g. vincaleucoblastine

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicinal Preparation (AREA)
  • Distillation Of Fermentation Liquor, Processing Of Alcohols, Vinegar And Beer (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
ES502644A 1980-06-10 1981-05-30 Procedimiento de obtencion de nuevos derivados de la vin- blastina Granted ES502644A0 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
LU82514A LU82514A1 (fr) 1980-06-10 1980-06-10 Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique
LU83034A LU83034A1 (fr) 1980-12-23 1980-12-23 Derives n-(vinblastinoyl-23) d'acides amines et de peptides, leur preparation et leur application therapeutique

Publications (2)

Publication Number Publication Date
ES8203385A1 ES8203385A1 (es) 1982-04-01
ES502644A0 true ES502644A0 (es) 1982-04-01

Family

ID=26640267

Family Applications (1)

Application Number Title Priority Date Filing Date
ES502644A Granted ES502644A0 (es) 1980-06-10 1981-05-30 Procedimiento de obtencion de nuevos derivados de la vin- blastina

Country Status (21)

Country Link
US (1) US4388305A (enExample)
EP (1) EP0041935B1 (enExample)
AT (2) AT390793B (enExample)
AU (1) AU541747B2 (enExample)
CA (1) CA1196326A (enExample)
DD (1) DD160417A5 (enExample)
DE (2) DE3122479A1 (enExample)
DK (1) DK160614C (enExample)
ES (1) ES502644A0 (enExample)
FR (1) FR2483926A1 (enExample)
GB (1) GB2078730A (enExample)
GR (1) GR74565B (enExample)
HU (1) HU185261B (enExample)
IE (1) IE51403B1 (enExample)
IL (1) IL63038A0 (enExample)
IT (1) IT1144601B (enExample)
NL (1) NL8102802A (enExample)
NZ (1) NZ197299A (enExample)
OA (1) OA06421A (enExample)
PT (1) PT73161B (enExample)
SE (1) SE8103594L (enExample)

Families Citing this family (37)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
LU83822A1 (fr) * 1981-12-08 1983-09-01 Omnichem Sa Derives n-(vinblastinoyl-23)d'acides amines,leur preparation et leur application therapeutique
US4639456A (en) * 1980-06-10 1987-01-27 Omnichem S.A. Vinblastin-23-oyl amino acid derivatives
IT1170152B (it) * 1982-07-19 1987-06-03 Lilly Co Eli Miglioramenti a o riguardanti formulazioni di vinca-alcaloidi
GR79898B (enExample) * 1983-03-30 1984-10-31 Lilly Industries Ltd
GR81790B (enExample) * 1983-04-29 1984-12-12 Omnichem Sa
US4675400A (en) * 1985-06-17 1987-06-23 Eli Lilly And Company Bifunctional derivatives of 4-desacetyl indole-dihydroindole alkaloids
US4667030A (en) * 1985-06-17 1987-05-19 Eli Lilly And Company Hydrazide succinimide derivatives of antineoplastic indole-dihydroindole alkaloids
FI860456A7 (fi) * 1985-07-16 1987-01-17 Huhtamaeki Oy Laeaeketehdas Le Bis-indolalkaloiders proteinkonjugat, bis-indolalkaloider, deras framstaellning och anvaendning.
EP0232693A3 (fr) * 1985-12-16 1988-04-06 La Region Wallonne Conjugués de la vinblastine et de ses dérivés, procédé pour leur préparation et compositions pharmaceutiques les contenant
US4831038A (en) * 1986-01-13 1989-05-16 Ire-Celltarg S.A. Vinblastine derivatives and pharmaceutical composition containing them
EP0316030B1 (en) * 1987-11-11 1991-12-18 Akzo N.V. Vincristine-containing product
FR2623504B1 (fr) * 1987-11-25 1990-03-09 Adir Nouveaux derives n-(vinblastinoyl-23) d'acide amino-1 methylphosphonique, leurs procedes de preparation et les compositions pharmaceutiques qui les contiennent
FR2626882B1 (fr) * 1988-02-08 1991-11-08 Ire Celltarg Sa Conjugues de derives de vinca comportant une chaine detergente en position c-3
US4980343A (en) * 1988-10-27 1990-12-25 Bayer Aktiengesellschaft Aminooxodihydroisoindoloquinazoline carcinostatic agents
US5043340A (en) * 1990-04-03 1991-08-27 Eli Lilly And Company Derivatives of 4-desacetyl VLB C-3 carboxhydrazide
US5043336A (en) * 1990-04-03 1991-08-27 Eli Lilly And Company Cyclic imide derivatives of 4-desacetyl VLB c-3 carboxhydrazide
US6143864A (en) * 1994-06-28 2000-11-07 Merck & Co., Inc. Peptides
US5866679A (en) * 1994-06-28 1999-02-02 Merck & Co., Inc. Peptides
US5599686A (en) * 1994-06-28 1997-02-04 Merck & Co., Inc. Peptides
EP1880737A1 (fr) * 1994-08-19 2008-01-23 La Region Wallonne Composés, composition pharmaceutique et dispositif de diagnostic les comprenant et leur utilisation
BE1008581A3 (fr) * 1994-08-19 1996-06-04 Wallone Region Prodrogues, composition pharmaceutique les comprenant et leur utilisation.
US5998362A (en) * 1996-09-12 1999-12-07 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US5948750A (en) * 1996-10-30 1999-09-07 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US6127333A (en) * 1997-07-10 2000-10-03 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US6391305B1 (en) 1997-09-10 2002-05-21 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
AU5240999A (en) * 1998-07-31 2000-02-21 Goldsmith Seeds Inc. Trimeric and polymeric alkaloids
DE19842416A1 (de) * 1998-09-16 2000-04-13 Max Planck Gesellschaft Sekundäre Amine zur Prävention und Therapie von Erkrankungen, die durch Oxidationsprozesse verursacht oder verstärkt werden
US7425541B2 (en) * 1998-12-11 2008-09-16 Medarex, Inc. Enzyme-cleavable prodrug compounds
JP2004510702A (ja) 2000-06-14 2004-04-08 メダレックス，インコーポレイティド イソロイシンを有するプロドラッグ化合物
US20030232760A1 (en) * 2001-09-21 2003-12-18 Merck & Co., Inc. Conjugates useful in the treatment of prostate cancer
US7235564B2 (en) * 2003-12-04 2007-06-26 Amr Technology, Inc. Vinorelbine derivatives
EP1689395B1 (en) * 2003-12-04 2016-02-17 Albany Molecular Research, Inc. Vinca derivatives
US20080125451A1 (en) * 2006-09-12 2008-05-29 Amr Technology, Inc. Vinorelbine derivatives
WO2008033930A2 (en) * 2006-09-12 2008-03-20 Amr Technology, Inc. Vinca derivatives
JP7620649B2 (ja) 2020-06-10 2025-01-23 アリゴス セラピューティクス インコーポレイテッド コロナウイルス、ピコルナウイルス及びノロウイルス感染を治療するための抗ウイルス化合物
AU2022306289A1 (en) 2021-07-09 2024-01-18 Aligos Therapeutics, Inc. Anti-viral compounds
WO2023043816A1 (en) 2021-09-17 2023-03-23 Aligos Therapeutics, Inc. Anti-viral compounds for treating coronavirus, picornavirus, and norovirus infections

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3387001A (en) * 1964-10-19 1968-06-04 Lilly Co Eli Novel aminoacyl esters of desacetyl vincaleukoblastine
AR204004A1 (es) * 1973-04-02 1975-11-12 Lilly Co Eli Procedimientos para preparar derivados de vinblastina leurosidina y leurocristina
GR69783B (enExample) * 1976-09-08 1982-07-07 Lilly Co Eli
US4203898A (en) * 1977-08-29 1980-05-20 Eli Lilly And Company Amide derivatives of VLB, leurosidine, leurocristine and related dimeric alkaloids

Also Published As

Publication number Publication date
EP0041935B1 (fr) 1984-09-19
ATA253881A (de) 1989-12-15
AT390793B (de) 1990-06-25
NZ197299A (en) 1985-10-11
EP0041935A1 (fr) 1981-12-16
OA06421A (fr) 1981-09-30
FR2483926A1 (fr) 1981-12-11
ES8203385A1 (es) 1982-04-01
IT1144601B (it) 1986-10-29
GB2078730A (en) 1982-01-13
DK160614B (da) 1991-04-02
PT73161A (fr) 1981-07-01
IE811275L (en) 1981-12-10
IL63038A0 (en) 1981-09-13
AU541747B2 (en) 1985-01-17
SE8103594L (sv) 1981-12-11
AU7126281A (en) 1981-12-17
PT73161B (fr) 1982-07-16
DK250181A (da) 1981-12-11
DK160614C (da) 1991-09-23
DE3166150D1 (en) 1984-10-25
DE3122479A1 (de) 1982-06-16
IT8167782A0 (it) 1981-06-08
DD160417A5 (de) 1983-07-27
US4388305A (en) 1983-06-14
IE51403B1 (en) 1986-12-24
CA1196326A (en) 1985-11-05
HU185261B (en) 1984-12-28
NL8102802A (nl) 1982-01-04
ATE9475T1 (de) 1984-10-15
FR2483926B1 (enExample) 1983-07-29
GR74565B (enExample) 1984-06-29

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19960603