ES484571A1 - Procedimiento para la obtencion de compuestos de n-oxaciclil-alquil-piperidil-diaza - Google Patents
Procedimiento para la obtencion de compuestos de n-oxaciclil-alquil-piperidil-diazaInfo
- Publication number
- ES484571A1 ES484571A1 ES484571A ES484571A ES484571A1 ES 484571 A1 ES484571 A1 ES 484571A1 ES 484571 A ES484571 A ES 484571A ES 484571 A ES484571 A ES 484571A ES 484571 A1 ES484571 A1 ES 484571A1
- Authority
- ES
- Spain
- Prior art keywords
- lower alkyl
- compounds
- hydrogen
- oxacyclylalkyl
- piperidines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Medicinal Chemistry (AREA)
- Psychiatry (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Procedimiento para la obtención de compuestos de N-oxaciclil-alquil- piperidil-diaza, de fórmula general I **(Fórmula)** donde e Ph significa 1, 2-fenileno insustituido, ó 1, 2-fenileno que está sustituido por 1 a 3 sustituyentes iguales o diferentes del grupo compuesto de alquilo inferior, alcoxi inferior, alquilendioxi inferior, halógeno ó trifluormetilo, cada uno de los símbolos R1 y R2 significa hidrogeno ó alquilo inferior, cada uno de los símbolos R3 y R4 significa hidrógeno ó alquilo inferior ó (R3 + R4) está por Ph ó alquileno inferior, que separa los dos átomos de nitrógeno por 2 hasta 3 átomos de carbono, R5 significa hidrógeno, alquilo inferior ó HPh, significa oxo, tioxo, imino ó alquilo inferior-imino, Y significa epoxi, epitio ó sulfinilo, m está por un número entero de 1 hasta 7, cada uno de los símbolos p y q significa un número entero de 1 hasta 3, donde (p + q) es el número 4, y las sales de adición de estos compuestos.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88808978A | 1978-03-20 | 1978-03-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES484571A1 true ES484571A1 (es) | 1980-05-16 |
Family
ID=25392505
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES478662A Expired ES478662A1 (es) | 1978-03-20 | 1979-03-15 | Procedimiento para a obtencion de compuestos de n-oxacicli-alquil-piperidil-diaza |
| ES484572A Expired ES484572A1 (es) | 1978-03-20 | 1979-09-28 | Procedimiento para la obtencion de compuestos de n-oxaciclil-alquil-piperidil-diaza |
| ES484571A Expired ES484571A1 (es) | 1978-03-20 | 1979-09-28 | Procedimiento para la obtencion de compuestos de n-oxaciclil-alquil-piperidil-diaza |
| ES484570A Expired ES484570A1 (es) | 1978-03-20 | 1979-09-28 | Procedimiento para la obtencion de compuestos de n-oxaciclil-alquil-piperidil-diaza |
Family Applications Before (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES478662A Expired ES478662A1 (es) | 1978-03-20 | 1979-03-15 | Procedimiento para a obtencion de compuestos de n-oxacicli-alquil-piperidil-diaza |
| ES484572A Expired ES484572A1 (es) | 1978-03-20 | 1979-09-28 | Procedimiento para la obtencion de compuestos de n-oxaciclil-alquil-piperidil-diaza |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES484570A Expired ES484570A1 (es) | 1978-03-20 | 1979-09-28 | Procedimiento para la obtencion de compuestos de n-oxaciclil-alquil-piperidil-diaza |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0004358B1 (es) |
| JP (1) | JPS54157570A (es) |
| AR (4) | AR227272A1 (es) |
| AT (1) | AT372088B (es) |
| AU (1) | AU529838B2 (es) |
| DD (1) | DD142341A5 (es) |
| DE (1) | DE2961738D1 (es) |
| DK (1) | DK113079A (es) |
| ES (4) | ES478662A1 (es) |
| FI (1) | FI66373C (es) |
| GB (1) | GB2019837B (es) |
| GR (1) | GR71865B (es) |
| HU (1) | HU182941B (es) |
| IL (1) | IL56908A (es) |
| MY (1) | MY8700122A (es) |
| NO (1) | NO150202C (es) |
| NZ (1) | NZ189939A (es) |
| PL (1) | PL116514B1 (es) |
| PT (1) | PT69369A (es) |
| ZA (2) | ZA79417B (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4329348A (en) * | 1979-02-26 | 1982-05-11 | Ciba-Geigy Corporation | N-Oxacyclic-alkylpiperidines as psychostimulants |
| DE3124366A1 (de) * | 1981-06-20 | 1982-12-30 | Hoechst Ag, 6000 Frankfurt | N-oxacyclyl-alkylpiperidin-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische praeparate und deren verwendung |
| FR2524887A1 (fr) * | 1982-04-08 | 1983-10-14 | Bouchara Emile | Nouvelles cyanoguanidines, leur procede d'obtention et les compositions pharmaceutiques en renfermant |
| FR2525600A1 (fr) * | 1982-04-21 | 1983-10-28 | Bouchara Emile | Nouvelles carboxamidoguanidines, leur procede d'obtention et les compositions pharmaceutiques en renfermant |
| US4556660A (en) * | 1982-07-12 | 1985-12-03 | Janssen Pharmaceutica N.V. | N-(Bicyclic heterocyclyl)-4-piperidinamines |
| JP2807577B2 (ja) * | 1990-06-15 | 1998-10-08 | エーザイ株式会社 | 環状アミド誘導体 |
| SI9300097B (en) * | 1992-02-27 | 2001-12-31 | Janssen Pharmaceutica Nv | (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines |
| US5703115A (en) * | 1993-02-19 | 1997-12-30 | Janssen Pharmaceutica, N.V. | (benzodioxan, benzofuran or benzopyran) alkylamino! alkyl substituted guanidines |
| US6133277A (en) * | 1997-12-05 | 2000-10-17 | Janssen Pharmaceutica N.V. | (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties |
| CZ20014167A3 (cs) | 1999-06-02 | 2002-06-12 | Janssen Pharmaceutica N. V. | Pyrrolidinylem, piperidinylem nebo homopiperidinylem substituované deriváty benzodioxanu, benzofuranu nebo benzopyranu |
| HUP0201404A3 (en) | 1999-06-02 | 2005-02-28 | Janssen Pharmaceutica Nv | Aminoalkyl substituted benzodioxan, benzofuran or benzopyran derivatives, pharmaceutical compositions containing them and their use and process for their preparations |
| JO2352B1 (en) * | 2000-06-22 | 2006-12-12 | جانسين فارماسيوتيكا ان. في | Compounds for the treatment of non-adaptation of the bottom of the uterus |
| CA2597616A1 (en) | 2005-02-17 | 2006-08-24 | Wyeth | Cycloalkylfused indole, benzothiophene, benzofuran and indene derivatives |
| CN114920686B (zh) * | 2022-05-20 | 2023-11-24 | 山东农业大学 | 5-(苯磺酰基)-n-哌啶-4-基-2-(三氟甲基)苯磺酰胺盐酸盐的合成方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3910930A (en) * | 1973-01-04 | 1975-10-07 | Janssen Pharmaceutica Nv | 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones |
-
1977
- 1977-08-17 GR GR58624A patent/GR71865B/el unknown
-
1979
- 1979-01-31 ZA ZA79417A patent/ZA79417B/xx unknown
- 1979-03-15 GB GB7909231A patent/GB2019837B/en not_active Expired
- 1979-03-15 ES ES478662A patent/ES478662A1/es not_active Expired
- 1979-03-16 DE DE7979100815T patent/DE2961738D1/de not_active Expired
- 1979-03-16 EP EP79100815A patent/EP0004358B1/de not_active Expired
- 1979-03-16 FI FI790894A patent/FI66373C/fi not_active IP Right Cessation
- 1979-03-17 PL PL1979214206A patent/PL116514B1/pl unknown
- 1979-03-19 AT AT0204479A patent/AT372088B/de not_active IP Right Cessation
- 1979-03-19 HU HU79CI1923A patent/HU182941B/hu unknown
- 1979-03-19 DD DD79211661A patent/DD142341A5/de unknown
- 1979-03-19 AU AU45243/79A patent/AU529838B2/en not_active Ceased
- 1979-03-19 NZ NZ189939A patent/NZ189939A/xx unknown
- 1979-03-19 DK DK113079A patent/DK113079A/da not_active Application Discontinuation
- 1979-03-19 PT PT69369A patent/PT69369A/pt unknown
- 1979-03-19 NO NO790917A patent/NO150202C/no unknown
- 1979-03-19 IL IL56908A patent/IL56908A/xx unknown
- 1979-03-19 ZA ZA791276A patent/ZA791276B/xx unknown
- 1979-03-20 AR AR275879A patent/AR227272A1/es active
- 1979-03-20 JP JP3184279A patent/JPS54157570A/ja active Pending
- 1979-09-28 ES ES484572A patent/ES484572A1/es not_active Expired
- 1979-09-28 ES ES484571A patent/ES484571A1/es not_active Expired
- 1979-09-28 ES ES484570A patent/ES484570A1/es not_active Expired
-
1980
- 1980-10-20 AR AR282945A patent/AR227400A1/es active
- 1980-10-20 AR AR282946A patent/AR227527A1/es active
- 1980-10-20 AR AR282944A patent/AR231638A1/es active
-
1987
- 1987-12-30 MY MY122/87A patent/MY8700122A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB2019837B (en) | 1982-08-25 |
| ZA791276B (en) | 1980-03-26 |
| NO150202B (no) | 1984-05-28 |
| AR227400A1 (es) | 1982-10-29 |
| DE2961738D1 (en) | 1982-02-25 |
| AR227272A1 (es) | 1982-10-15 |
| FI66373B (fi) | 1984-06-29 |
| ATA204479A (de) | 1983-01-15 |
| PL214206A1 (es) | 1980-02-25 |
| ZA79417B (en) | 1980-01-30 |
| FI790894A (fi) | 1979-09-21 |
| IL56908A (en) | 1983-09-30 |
| NZ189939A (en) | 1981-12-15 |
| EP0004358B1 (de) | 1982-01-06 |
| ES484572A1 (es) | 1980-05-16 |
| HU182941B (en) | 1984-03-28 |
| FI66373C (fi) | 1984-10-10 |
| AU529838B2 (en) | 1983-06-23 |
| DD142341A5 (de) | 1980-06-18 |
| DK113079A (da) | 1979-09-21 |
| ES484570A1 (es) | 1980-05-16 |
| EP0004358A1 (de) | 1979-10-03 |
| PT69369A (en) | 1979-04-01 |
| IL56908A0 (en) | 1979-05-31 |
| MY8700122A (en) | 1987-12-31 |
| GB2019837A (en) | 1979-11-07 |
| PL116514B1 (en) | 1981-06-30 |
| JPS54157570A (en) | 1979-12-12 |
| AR227527A1 (es) | 1982-11-15 |
| NO790917L (no) | 1979-09-21 |
| AU4524379A (en) | 1979-09-27 |
| AR231638A1 (es) | 1985-01-31 |
| ES478662A1 (es) | 1980-01-16 |
| GR71865B (es) | 1983-07-07 |
| AT372088B (de) | 1983-08-25 |
| NO150202C (no) | 1984-09-05 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20000201 |