ES8301882A1 - Un procedimiento para la preparacion de un derivado de fene-tilamina - Google Patents

Un procedimiento para la preparacion de un derivado de fene-tilamina

Info

Publication number
ES8301882A1
ES8301882A1 ES504376A ES504376A ES8301882A1 ES 8301882 A1 ES8301882 A1 ES 8301882A1 ES 504376 A ES504376 A ES 504376A ES 504376 A ES504376 A ES 504376A ES 8301882 A1 ES8301882 A1 ES 8301882A1
Authority
ES
Spain
Prior art keywords
group
hydrogen atom
lower alkyl
alkyl group
represents hydrogen
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES504376A
Other languages
English (en)
Other versions
ES504376A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Yamanouchi Pharmaceutical Co Ltd
Original Assignee
Yamanouchi Pharmaceutical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP10417580A external-priority patent/JPS5728040A/ja
Priority claimed from JP9201081A external-priority patent/JPS57206652A/ja
Application filed by Yamanouchi Pharmaceutical Co Ltd filed Critical Yamanouchi Pharmaceutical Co Ltd
Publication of ES504376A0 publication Critical patent/ES504376A0/es
Publication of ES8301882A1 publication Critical patent/ES8301882A1/es
Expired legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/13Amines
    • A61K31/135Amines having aromatic rings, e.g. ketamine, nortriptyline
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/21Esters, e.g. nitroglycerine, selenocyanates
    • A61K31/255Esters, e.g. nitroglycerine, selenocyanates of sulfoxy acids or sulfur analogues thereof

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Emergency Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE UN DERIVADO DE FENETILAMINA, DE FORMULA (I), EN LA QUE R ES ALQUILO INFERIOR; R ES ALQUILO O ALCOXI INFERIORES; R Y R SON HIDROGENO O ALQUILO INFERIOR; R ES HIDROGENO O ALCOXI INFERIOR; X ES OXIGENO O METILENO; Y M Y N VALEN 1-3 Y 0-2, RESPECTIVAMENTE. CONSISTE EN LA REACCION DE UN COMPUESTO DE FORMULA (II), CON UNA AMINA DE FORMULA (III), EN LAS QUE W ES UN RADICAL DE FORMULA (IV) O (V); Z ES HIDROGENO O BENICLO; HAL ES HALOGENO; Y LOS DEMAS SIMBOLOS TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I). LA REACCION SE LLEVA A CABO EN UN DISOLVENTE, A LA TEMPERATURA DE REFLUJO DE LA MEZCLA DE REACCION. ESTOS COMPUESTOS TIENE APLICACIONES FARMACOLOGICAS COMO AGENTES HIPERTENSIVOS.
ES504376A 1980-07-29 1981-07-28 Un procedimiento para la preparacion de un derivado de fene-tilamina Expired ES8301882A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP10417580A JPS5728040A (en) 1980-07-29 1980-07-29 Phenylethanolamine derivative
JP9201081A JPS57206652A (en) 1981-06-15 1981-06-15 Substituted phenyl ether derivative

Publications (2)

Publication Number Publication Date
ES504376A0 ES504376A0 (es) 1982-12-16
ES8301882A1 true ES8301882A1 (es) 1982-12-16

Family

ID=26433470

Family Applications (1)

Application Number Title Priority Date Filing Date
ES504376A Expired ES8301882A1 (es) 1980-07-29 1981-07-28 Un procedimiento para la preparacion de un derivado de fene-tilamina

Country Status (7)

Country Link
US (2) US4880841A (es)
CA (1) CA1224494A (es)
DE (1) DE3128117A1 (es)
ES (1) ES8301882A1 (es)
FR (1) FR2487827A1 (es)
GB (1) GB2083022B (es)
IT (1) IT1172230B (es)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5198587A (en) * 1980-07-29 1993-03-30 Yamanouchi Pharmaceutical Co., Ltd. Phenethylamine derivatives
JPS6341451A (ja) * 1986-08-06 1988-02-22 Nippon Kayaku Co Ltd エ−テル誘導体およびそれを有効成分とする殺ダニ、殺虫組成物
WO1999057131A1 (en) * 1998-05-06 1999-11-11 Duke University Method of treating bladder and lower urinary tract syndromes
WO2005056521A1 (en) * 2003-12-09 2005-06-23 Cj Corporation Method of preparing optically pure phenethylamine derivatives
CN102050766B (zh) * 2009-11-03 2013-08-07 安徽省新星药物开发有限责任公司 一种盐酸氨磺洛尔的合成方法
WO2020112855A1 (en) * 2018-11-29 2020-06-04 Reform Biologics, Llc Excipient compounds for protein processing
US10478498B2 (en) 2014-06-20 2019-11-19 Reform Biologics, Llc Excipient compounds for biopolymer formulations
US20160074515A1 (en) 2014-06-20 2016-03-17 Reform Biologics, Llc Viscosity-reducing excipient compounds for protein formulations
US11357857B2 (en) 2014-06-20 2022-06-14 Comera Life Sciences, Inc. Excipient compounds for protein processing

Family Cites Families (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE1543372A1 (de) * 1966-10-18 1971-04-01 Boehringer Sohn Ingelheim Verfahren zur Herstellung von o-substituierten 3,4-Dioxyphenylalkanolaminen
GB1321701A (en) * 1969-10-01 1973-06-27 Continental Pharma Amino-alcohols their salts and process for prepairing the same
US4137328A (en) * 1970-07-18 1979-01-30 Pfizer Inc. Phenyl-alkanolamine, alkylamine and α-aminoalkyl ketone derivatives as heart stimulants
GB1390748A (en) * 1973-04-09 1975-04-16 Continental Pharma Alkyl and cycloalkylthiophenylalkylaminoalkanols their salts and the preparation thereof
US4048229A (en) * 1975-01-08 1977-09-13 Smithkline Corporation α-AMINOMETHYL-4-HYDROXY-3-METHYLSULFONYL BENZYL ALCOHOLS
US4119729A (en) * 1975-12-19 1978-10-10 Mead Johnson & Company Alkylsulfonylphenoxypropanolamine therapeutic process
US4695589A (en) * 1976-06-25 1987-09-22 Sterling Drug Inc. Alpha-(aminoalkyl-4-hydroxy-3-(alkylthio)benzenemethanols
US4327224A (en) * 1976-06-25 1982-04-27 Sterling Drug Inc. α-[(alkylamino)alkyl]-4-hydroxy-3-(alkylthio)benzenemethanols, derivatives thereof and intermediates therefor
GB1544872A (en) * 1976-06-25 1979-04-25 Sterling Drug Inc 4-hydroxyphenylalkanolamine derivatives and preparation thereof
US4374149A (en) * 1977-06-03 1983-02-15 Sterling Drug Inc. α-{[(Arylalkyl)amino]alkyl}-4-hydroxy-3-(lower-alkylsulfinyl)benzenemethanols
JPS552639A (en) * 1978-06-21 1980-01-10 Yamanouchi Pharmaceut Co Ltd Phenylethanolamine derivative and its preparation
CA1147342A (en) * 1977-10-12 1983-05-31 Kazuo Imai Process of producing novel phenylethanolamine derivatives
LU79970A1 (fr) * 1978-07-13 1980-02-14 Continental Pharma Procede de preparation de derives de 1-phenyl-1-propanol
US4304790A (en) * 1979-06-12 1981-12-08 Schering Corporation 2-(Alkylthio, alkylsulfinyl or alkylsulfonyl)-4-[2-anilinoalkylamino)-1-hydroxyethyl]phenols and derivatives thereof
EP0040000B1 (en) * 1980-05-08 1983-10-12 Beecham Group Plc Arylethanolamine derivatives, their preparation and use in pharmaceutical compositions
US4379166A (en) * 1981-08-03 1983-04-05 Schering Corporation Arylmethoxy-, arylmethylthio-, heteroarylmethoxy-, and heteroarylmethylthio-alkylaminoalcohols
US4720586A (en) * 1983-12-06 1988-01-19 Fisons, Plc Substituted 3,4-dihydroxy-phenylethylamino compounds

Also Published As

Publication number Publication date
FR2487827A1 (fr) 1982-02-05
IT1172230B (it) 1987-06-18
GB2083022A (en) 1982-03-17
US4880841A (en) 1989-11-14
ES504376A0 (es) 1982-12-16
US5063246A (en) 1991-11-05
GB2083022B (en) 1984-09-12
IT8168052A0 (it) 1981-07-28
FR2487827B1 (es) 1985-04-19
CA1224494A (en) 1987-07-21
DE3128117A1 (de) 1982-03-11

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970303