ATE28631T1 - Substituierte 1-azaspiro(4.5)-decane und 1azaspiro(5.5)-undecane, zwischenprodukte, verfahren zu ihrer herstellung und verwendung als heilmittel. - Google Patents

Substituierte 1-azaspiro(4.5)-decane und 1azaspiro(5.5)-undecane, zwischenprodukte, verfahren zu ihrer herstellung und verwendung als heilmittel.

Info

Publication number
ATE28631T1
ATE28631T1 AT84101085T AT84101085T ATE28631T1 AT E28631 T1 ATE28631 T1 AT E28631T1 AT 84101085 T AT84101085 T AT 84101085T AT 84101085 T AT84101085 T AT 84101085T AT E28631 T1 ATE28631 T1 AT E28631T1
Authority
AT
Austria
Prior art keywords
azaspiro
undecanes
decanes
substituted
preparation
Prior art date
Application number
AT84101085T
Other languages
English (en)
Inventor
Joseph T Strupczewski
Beth A Gardner
Original Assignee
Hoechst Roussel Pharma
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Roussel Pharma filed Critical Hoechst Roussel Pharma
Application granted granted Critical
Publication of ATE28631T1 publication Critical patent/ATE28631T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D221/00—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00
    • C07D221/02—Heterocyclic compounds containing six-membered rings having one nitrogen atom as the only ring hetero atom, not provided for by groups C07D211/00 - C07D219/00 condensed with carbocyclic rings or ring systems
    • C07D221/20—Spiro-condensed ring systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/54—Spiro-condensed

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pain & Pain Management (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Indole Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
AT84101085T 1983-02-09 1984-02-03 Substituierte 1-azaspiro(4.5)-decane und 1azaspiro(5.5)-undecane, zwischenprodukte, verfahren zu ihrer herstellung und verwendung als heilmittel. ATE28631T1 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/465,146 US4430335A (en) 1983-02-09 1983-02-09 Substituted 1-azaspiro[4,5]decanes and their analgesic compositions
EP84101085A EP0116347B1 (de) 1983-02-09 1984-02-03 Substituierte 1-Azaspiro(4.5)-decane und 1-Azaspiro(5.5)-undecane, Zwischenprodukte, Verfahren zu ihrer Herstellung und Verwendung als Heilmittel

Publications (1)

Publication Number Publication Date
ATE28631T1 true ATE28631T1 (de) 1987-08-15

Family

ID=23846664

Family Applications (1)

Application Number Title Priority Date Filing Date
AT84101085T ATE28631T1 (de) 1983-02-09 1984-02-03 Substituierte 1-azaspiro(4.5)-decane und 1azaspiro(5.5)-undecane, zwischenprodukte, verfahren zu ihrer herstellung und verwendung als heilmittel.

Country Status (6)

Country Link
US (1) US4430335A (de)
EP (1) EP0116347B1 (de)
JP (1) JPS60500765A (de)
AT (1) ATE28631T1 (de)
DE (1) DE3465080D1 (de)
WO (1) WO1984003090A1 (de)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4430335A (en) * 1983-02-09 1984-02-07 Hoechst-Roussel Pharmaceuticals Inc. Substituted 1-azaspiro[4,5]decanes and their analgesic compositions
US4570010A (en) * 1983-03-23 1986-02-11 The Upjohn Company Product
US5286723A (en) * 1988-08-31 1994-02-15 Daiichi Seiyaku Co., Ltd. Spiro compound
CA1336090C (en) * 1988-08-31 1995-06-27 Isao Hayakawa Spiro-substituted cyclic amines of quinolone derivatives
GB9223445D0 (en) * 1992-11-09 1992-12-23 Boots Co Plc Therapeutic agents
NZ286951A (en) * 1995-07-13 1998-02-26 Anormed Inc Substituted Under N-n-diethyl-8,8-dipropyl-2-azaspiro[4,5]decane-2-propanamine dimaleate
DE10146910A1 (de) * 2001-09-24 2003-04-10 Bayer Cropscience Ag Spirocyclische 3-Phenyl-3-substituierte-4-ketolaktame und -laktone
DE10210190A1 (de) * 2002-03-07 2003-09-25 Sanol Arznei Schwarz Gmbh Aza-Spiroverbindungen
DE10210195B4 (de) 2002-03-07 2005-12-15 Schwarz Pharma Ag Verwendung von 1,3-Diazaspiro-[4,5]decan-2,4-dithion zur Behandlung von Schmerz

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH579547A5 (de) * 1973-07-25 1976-09-15 Ciba Geigy Ag
US4430335A (en) * 1983-02-09 1984-02-07 Hoechst-Roussel Pharmaceuticals Inc. Substituted 1-azaspiro[4,5]decanes and their analgesic compositions

Also Published As

Publication number Publication date
US4430335A (en) 1984-02-07
JPS60500765A (ja) 1985-05-23
EP0116347A1 (de) 1984-08-22
JPS6216947B2 (de) 1987-04-15
DE3465080D1 (en) 1987-09-03
WO1984003090A1 (en) 1984-08-16
EP0116347B1 (de) 1987-07-29

Similar Documents

Publication Publication Date Title
DE3482039D1 (de) Benzofurancarboxamide, verfahren zu ihrer herstellung und pharmazeutische zubereitungen die sie enthalten.
ZA82567B (en) Process for the preparation of 2-penem compounds,novel 2-penem compounds produced thereby,and pharmaceutical compositions containing them
ES8400422A1 (es) "procedimiento de preparacion de eteres triciclicos, asi como de sus sales de adicion con un acido mineral u organico terapeuticamente compatible".
ES8206556A1 (es) Un procedimiento para la preparacion de esteres de heparina.
ATE28631T1 (de) Substituierte 1-azaspiro(4.5)-decane und 1azaspiro(5.5)-undecane, zwischenprodukte, verfahren zu ihrer herstellung und verwendung als heilmittel.
ES8105988A1 (es) Procedimiento para la preparacion de acidos oxirancarboxili-cos sustituidos
DE2965904D1 (en) 3,20-dioxo-4,9-diene-21-hydroxy-steroid compounds, process for their preparation, their use in medicines and pharmaceutical compositions containing them
ES8505518A1 (es) Procedimiento para preparar derivados de aminoacidos
ES2019163A6 (es) Procedimiento para preparar derivados de imidazol.
ES8101550A1 (es) Un procedimiento para la preparacion de nuevos derivados de 2-pirrolidin-metanol.
ES8202780A1 (es) Procedimiento para la preparacion de acidos oxocarboxilicos sustituidos
ATE13880T1 (de) N-2-hydroxypropyl-piperidine und verfahren zu ihrer herstellung.
MY110450A (en) Imidazolylmethyl-pyridines, their production their use as pharmaceuticals and pharmaceutical compositions containing them
ES8301882A1 (es) Un procedimiento para la preparacion de un derivado de fene-tilamina
ES8308554A1 (es) "procedimiento de obtencion de productos para tratamiento de polimeros polihidroxilicos o poliaminicos".
ES8400743A1 (es) "procedimiento para la preparacion de compuestos de 1-fenilindazol-3-ona".
ATE18667T1 (de) Aethenylimidazol-derivate, verfahren zu deren herstellung und deren pharmazeutische zusammensetzungen, bei deren herstellung verwendbare zwischenprodukte und verfahren zu deren herstellung.
GR3019711T3 (en) Spiro-indoline-oxazine compounds with photochromatic and photosensitizing characteristics and the process for their preparation
ES8403891A1 (es) Un procedimiento para la preparacion de un derivado del acido furiloxazolila-cetico
ES8307780A1 (es) "procedimiento para la preparacion de acidos fenilalcohiloxirancarboxilicos".
JPS5576872A (en) Imidazolidinone derivative
DE3564426D1 (en) Polyprenyl compound, process of producing it and pharmaceutical use
HUT65533A (en) Process for producing 2-amino-pyrimidine-4-carboxamide derivatives and pharmaceutical preparations containing them
DE69125569D1 (de) 8-Azabicyclo[3.2.1]octylalkylthiazolidinone, Verfahren zu ihrer Herstellung und ihre Verwendung als Arzneimittel
ES8307233A1 (es) Procedimiento para preparar derivados del acido 1,4-tiazan-3-carboxilico.

Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee