ES484570A1 - Procedimiento para la obtencion de compuestos de n-oxaciclil-alquil-piperidil-diaza - Google Patents
Procedimiento para la obtencion de compuestos de n-oxaciclil-alquil-piperidil-diazaInfo
- Publication number
- ES484570A1 ES484570A1 ES484570A ES484570A ES484570A1 ES 484570 A1 ES484570 A1 ES 484570A1 ES 484570 A ES484570 A ES 484570A ES 484570 A ES484570 A ES 484570A ES 484570 A1 ES484570 A1 ES 484570A1
- Authority
- ES
- Spain
- Prior art keywords
- lower alkyl
- compounds
- hydrogen
- oxacyclylalkyl
- piperidines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/14—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/24—Antidepressants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/26—Psychostimulants, e.g. nicotine, cocaine
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Psychiatry (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Hydrogenated Pyridines (AREA)
Abstract
Procedimiento para la obtención de compuestos de N-oxaciclil-alquil- piperidil-diaza, de fórmula general I **(Fórmula)** donde Ph significa 1, 2-fenileno insustituido, ¿0 1,2-fenileno que está sustituido por 1 a 3 sustituyentes iguales o diferentes del grupo compuesto de alquilo inferior, alcoxi inferior, alquilendioxi inferior, halógeno ó trifluormetilo, cada uno de los símbolos R1 y R2 significa hidrógeno ó alquilo inferior, cada uno de los símbolos R3 y R4 significa hidrógeno ó alquilo inferior ó (R3 + R4) está por Ph ó alquileno inferior, que separa los dos átomos de nitrógeno por 2 hasta 3 átomos de carbono, R5 significa hidrógeno, alquilo inferior ó HPh, X significa oxo, tioxo, imino ó alquilo inferior-imino, Y significa qposi, epitio ó sulfinilo, m está por un número entero de 1 hasta 7, cada uno de los símbolos p y q significa un número entero de 1 hasta 3, donde (p + q) es el número 4, y las sales de adición de ácido de estos compuestos.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US88808978A | 1978-03-20 | 1978-03-20 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES484570A1 true ES484570A1 (es) | 1980-05-16 |
Family
ID=25392505
Family Applications (4)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES478662A Expired ES478662A1 (es) | 1978-03-20 | 1979-03-15 | Procedimiento para a obtencion de compuestos de n-oxacicli-alquil-piperidil-diaza |
| ES484571A Expired ES484571A1 (es) | 1978-03-20 | 1979-09-28 | Procedimiento para la obtencion de compuestos de n-oxaciclil-alquil-piperidil-diaza |
| ES484572A Expired ES484572A1 (es) | 1978-03-20 | 1979-09-28 | Procedimiento para la obtencion de compuestos de n-oxaciclil-alquil-piperidil-diaza |
| ES484570A Expired ES484570A1 (es) | 1978-03-20 | 1979-09-28 | Procedimiento para la obtencion de compuestos de n-oxaciclil-alquil-piperidil-diaza |
Family Applications Before (3)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES478662A Expired ES478662A1 (es) | 1978-03-20 | 1979-03-15 | Procedimiento para a obtencion de compuestos de n-oxacicli-alquil-piperidil-diaza |
| ES484571A Expired ES484571A1 (es) | 1978-03-20 | 1979-09-28 | Procedimiento para la obtencion de compuestos de n-oxaciclil-alquil-piperidil-diaza |
| ES484572A Expired ES484572A1 (es) | 1978-03-20 | 1979-09-28 | Procedimiento para la obtencion de compuestos de n-oxaciclil-alquil-piperidil-diaza |
Country Status (20)
| Country | Link |
|---|---|
| EP (1) | EP0004358B1 (es) |
| JP (1) | JPS54157570A (es) |
| AR (4) | AR227272A1 (es) |
| AT (1) | AT372088B (es) |
| AU (1) | AU529838B2 (es) |
| DD (1) | DD142341A5 (es) |
| DE (1) | DE2961738D1 (es) |
| DK (1) | DK113079A (es) |
| ES (4) | ES478662A1 (es) |
| FI (1) | FI66373C (es) |
| GB (1) | GB2019837B (es) |
| GR (1) | GR71865B (es) |
| HU (1) | HU182941B (es) |
| IL (1) | IL56908A (es) |
| MY (1) | MY8700122A (es) |
| NO (1) | NO150202C (es) |
| NZ (1) | NZ189939A (es) |
| PL (1) | PL116514B1 (es) |
| PT (1) | PT69369A (es) |
| ZA (2) | ZA79417B (es) |
Families Citing this family (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4329348A (en) * | 1979-02-26 | 1982-05-11 | Ciba-Geigy Corporation | N-Oxacyclic-alkylpiperidines as psychostimulants |
| DE3124366A1 (de) * | 1981-06-20 | 1982-12-30 | Hoechst Ag, 6000 Frankfurt | N-oxacyclyl-alkylpiperidin-derivate, verfahren zu ihrer herstellung, sie enthaltende pharmazeutische praeparate und deren verwendung |
| FR2524887A1 (fr) * | 1982-04-08 | 1983-10-14 | Bouchara Emile | Nouvelles cyanoguanidines, leur procede d'obtention et les compositions pharmaceutiques en renfermant |
| FR2525600A1 (fr) * | 1982-04-21 | 1983-10-28 | Bouchara Emile | Nouvelles carboxamidoguanidines, leur procede d'obtention et les compositions pharmaceutiques en renfermant |
| US4556660A (en) * | 1982-07-12 | 1985-12-03 | Janssen Pharmaceutica N.V. | N-(Bicyclic heterocyclyl)-4-piperidinamines |
| JP2807577B2 (ja) * | 1990-06-15 | 1998-10-08 | エーザイ株式会社 | 環状アミド誘導体 |
| SI9300097B (en) * | 1992-02-27 | 2001-12-31 | Janssen Pharmaceutica Nv | (benzodioxan, benzofuran or benzopyran) alkylamino) alkyl substituted guanidines |
| US5703115A (en) * | 1993-02-19 | 1997-12-30 | Janssen Pharmaceutica, N.V. | (benzodioxan, benzofuran or benzopyran) alkylamino! alkyl substituted guanidines |
| US6133277A (en) * | 1997-12-05 | 2000-10-17 | Janssen Pharmaceutica N.V. | (Benzodioxan, benzofuran or benzopyran) derivatives having fundic relaxation properties |
| UA73123C2 (en) | 1999-06-02 | 2005-06-15 | Janssen Pharmaceutica Nv | Derivatives of benzodioxane, benzofuran or benzopyran substituted by pyrolidinyl, piperidinyl or homopiperidinyl |
| IL146840A0 (en) | 1999-06-02 | 2002-07-25 | Janssen Pharmaceutica Nv | Aminoalkyl substituted (benzodioxan, benzofuran or benzopyran) derivatives |
| JO2352B1 (en) * | 2000-06-22 | 2006-12-12 | جانسين فارماسيوتيكا ان. في | Compounds for the treatment of non-adaptation of the bottom of the uterus |
| WO2006089053A2 (en) | 2005-02-17 | 2006-08-24 | Wyeth | Cycloalkylfused indole, benzothiophene, benzofuran and indene derivatives |
| CN114920686B (zh) * | 2022-05-20 | 2023-11-24 | 山东农业大学 | 5-(苯磺酰基)-n-哌啶-4-基-2-(三氟甲基)苯磺酰胺盐酸盐的合成方法 |
Family Cites Families (1)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3910930A (en) * | 1973-01-04 | 1975-10-07 | Janssen Pharmaceutica Nv | 1-{55 1-{8 2-(1,4-Benzodioxan-2-yl)-2-hydroxyethyl{9 -4-piperidyl{56 -2-benzimidazolinones |
-
1977
- 1977-08-17 GR GR58624A patent/GR71865B/el unknown
-
1979
- 1979-01-31 ZA ZA79417A patent/ZA79417B/xx unknown
- 1979-03-15 ES ES478662A patent/ES478662A1/es not_active Expired
- 1979-03-15 GB GB7909231A patent/GB2019837B/en not_active Expired
- 1979-03-16 FI FI790894A patent/FI66373C/fi not_active IP Right Cessation
- 1979-03-16 DE DE7979100815T patent/DE2961738D1/de not_active Expired
- 1979-03-16 EP EP79100815A patent/EP0004358B1/de not_active Expired
- 1979-03-17 PL PL1979214206A patent/PL116514B1/pl unknown
- 1979-03-19 IL IL56908A patent/IL56908A/xx unknown
- 1979-03-19 NZ NZ189939A patent/NZ189939A/xx unknown
- 1979-03-19 DD DD79211661A patent/DD142341A5/de unknown
- 1979-03-19 HU HU79CI1923A patent/HU182941B/hu unknown
- 1979-03-19 NO NO790917A patent/NO150202C/no unknown
- 1979-03-19 AT AT0204479A patent/AT372088B/de not_active IP Right Cessation
- 1979-03-19 ZA ZA791276A patent/ZA791276B/xx unknown
- 1979-03-19 AU AU45243/79A patent/AU529838B2/en not_active Ceased
- 1979-03-19 DK DK113079A patent/DK113079A/da not_active Application Discontinuation
- 1979-03-19 PT PT69369A patent/PT69369A/pt unknown
- 1979-03-20 AR AR275879A patent/AR227272A1/es active
- 1979-03-20 JP JP3184279A patent/JPS54157570A/ja active Pending
- 1979-09-28 ES ES484571A patent/ES484571A1/es not_active Expired
- 1979-09-28 ES ES484572A patent/ES484572A1/es not_active Expired
- 1979-09-28 ES ES484570A patent/ES484570A1/es not_active Expired
-
1980
- 1980-10-20 AR AR282944A patent/AR231638A1/es active
- 1980-10-20 AR AR282945A patent/AR227400A1/es active
- 1980-10-20 AR AR282946A patent/AR227527A1/es active
-
1987
- 1987-12-30 MY MY122/87A patent/MY8700122A/xx unknown
Also Published As
| Publication number | Publication date |
|---|---|
| GB2019837B (en) | 1982-08-25 |
| AR231638A1 (es) | 1985-01-31 |
| FI790894A (fi) | 1979-09-21 |
| DK113079A (da) | 1979-09-21 |
| GB2019837A (en) | 1979-11-07 |
| DE2961738D1 (en) | 1982-02-25 |
| NO790917L (no) | 1979-09-21 |
| ES478662A1 (es) | 1980-01-16 |
| ES484572A1 (es) | 1980-05-16 |
| AR227272A1 (es) | 1982-10-15 |
| ZA79417B (en) | 1980-01-30 |
| NO150202C (no) | 1984-09-05 |
| GR71865B (es) | 1983-07-07 |
| EP0004358B1 (de) | 1982-01-06 |
| AT372088B (de) | 1983-08-25 |
| ZA791276B (en) | 1980-03-26 |
| PT69369A (en) | 1979-04-01 |
| ATA204479A (de) | 1983-01-15 |
| HU182941B (en) | 1984-03-28 |
| AU529838B2 (en) | 1983-06-23 |
| MY8700122A (en) | 1987-12-31 |
| DD142341A5 (de) | 1980-06-18 |
| IL56908A (en) | 1983-09-30 |
| FI66373B (fi) | 1984-06-29 |
| AR227400A1 (es) | 1982-10-29 |
| AU4524379A (en) | 1979-09-27 |
| IL56908A0 (en) | 1979-05-31 |
| NO150202B (no) | 1984-05-28 |
| EP0004358A1 (de) | 1979-10-03 |
| FI66373C (fi) | 1984-10-10 |
| AR227527A1 (es) | 1982-11-15 |
| ES484571A1 (es) | 1980-05-16 |
| PL116514B1 (en) | 1981-06-30 |
| PL214206A1 (es) | 1980-02-25 |
| JPS54157570A (en) | 1979-12-12 |
| NZ189939A (en) | 1981-12-15 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| ES478662A1 (es) | Procedimiento para a obtencion de compuestos de n-oxacicli-alquil-piperidil-diaza | |
| ES8306141A1 (es) | Un procedimiento para la produccion de un derivado de carbostirilo | |
| IL68075A0 (en) | Pyridine and pyrane derivatives,their preparation and pharmaceutical compositions containing them | |
| ES8306159A1 (es) | Un procedimiento para la preparacion de nuevos derivados de cefalosporina. | |
| ES8302656A1 (es) | "un procedimiento para la preparacion de nuevos derivados de piperidina" | |
| ES8301972A1 (es) | Procedimiento para la obtencion de n-oxidos de compuestos den-oxaciclil-alquil-piperidil-diaza | |
| SE8501421D0 (sv) | 1-(hydroximetyl)-1,6,7,11b-tetrahydro-2h,4h-(1,3)-oxazino- eller -tiazino(4,3-a)isokinolinderivat, forfarande for deras framstellning och farmaceutiska kompositioner innehallande dem | |
| ES486824A1 (es) | Procedimiento para la preparacion de nuevos derivados de 4- (naftilmetil) piperidinas | |
| ATE77818T1 (de) | Neue naphthylderivate, diese verbindungen enthaltende arzneimittel und verfahren zu ihrer herstellung. | |
| ES8205791A1 (es) | Procedimiento para la preparacion de derivados de imidazol del sistema de 1,4-benzodioxan-2-ilo | |
| ES8100284A1 (es) | Un procedimiento de preparacion de derivados del jurano | |
| ES8301882A1 (es) | Un procedimiento para la preparacion de un derivado de fene-tilamina | |
| ES8400743A1 (es) | "procedimiento para la preparacion de compuestos de 1-fenilindazol-3-ona". | |
| IL102792A0 (en) | Cyclic urea compounds and pharmaceutical compositions containing them | |
| ES8200113A1 (es) | Un procedimiento para la preparacion de derivados de cefalosporina. | |
| PT83786A (de) | Neue basisch substituierte pyridinverbindungen verfahren zu ihrer herstellung die sie enthaltenden arzneimittel und ihre verwendung | |
| ES8300778A1 (es) | Procedimiento de preparar nuevos compuestos citostaticos del tipo de las ruiblastinas y similares. | |
| ES8501382A1 (es) | Procedimiento para la preparacion de derivados de acido fenilacetico. | |
| ES8401059A1 (es) | Procedimiento para la preparacion de fenoleteres biciclicos. | |
| ES8400406A1 (es) | Procedimiento para preparar derivados de indano. | |
| ES8307233A1 (es) | Procedimiento para preparar derivados del acido 1,4-tiazan-3-carboxilico. | |
| SE8405338D0 (sv) | (1,3) oxazino (4,3-a) isoquinoline derivatives, process for their preparation and pharmaceutical compositions containing them | |
| IE801382L (en) | Piperidines. | |
| ES8704459A1 (es) | Procedimiento para la obtencion de acemetacina. | |
| ES8402821A1 (es) | Procedimiento de obtencion de las feniloxoalcoil piperidinas. |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 20000201 |