ES483977A1 - Procedimiento para la obtencion de derivados de acido hidroxiacetico - Google Patents
Procedimiento para la obtencion de derivados de acido hidroxiaceticoInfo
- Publication number
- ES483977A1 ES483977A1 ES483977A ES483977A ES483977A1 ES 483977 A1 ES483977 A1 ES 483977A1 ES 483977 A ES483977 A ES 483977A ES 483977 A ES483977 A ES 483977A ES 483977 A1 ES483977 A1 ES 483977A1
- Authority
- ES
- Spain
- Prior art keywords
- arthritic
- manufacture
- processes
- pharmaceutical compositions
- acid derivatives
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
- C07C59/40—Unsaturated compounds
- C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
- C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
- C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
- C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
- C07C45/46—Friedel-Crafts reactions
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
- C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
- C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Health & Medical Sciences (AREA)
- Oil, Petroleum & Natural Gas (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Abstract
Procedimiento para preparar derivados del ácido hidroxiacético y, más particularmente, para preparar derivados del ácido hidroxiacético que poseen propiedades antiartríticas útiles en el tratamiento de las enfermedades de las articulaciones artríticas. Es sabido que diversos ácidos 2-(benciloxi sustituido)acéticos y sus derivados 2-trifluorometilo hacen descender el nivel de por lo menos un factor que se cree está comprendido en la enfermedad ateroesclerótica, por ejemplo del nivel del colesterol en el suero, de los triglicéridos en el suero y del fibrinógeno en el plasma, y, en determinados casos, también poseen propiedades artiartríticas. También es sabido que diversos derivados del ácido 2-(fenoxi)fenilacético poseen propiedades hipocolesterolémicas.
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB7836173 | 1978-09-08 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES483977A1 true ES483977A1 (es) | 1980-04-16 |
Family
ID=10499548
Family Applications (2)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES483977A Expired ES483977A1 (es) | 1978-09-08 | 1979-09-07 | Procedimiento para la obtencion de derivados de acido hidroxiacetico |
| ES483978A Expired ES483978A1 (es) | 1978-09-08 | 1979-09-07 | Procedimiento para la obtencion de derivados de acido hidro-xialcanoico |
Family Applications After (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES483978A Expired ES483978A1 (es) | 1978-09-08 | 1979-09-07 | Procedimiento para la obtencion de derivados de acido hidro-xialcanoico |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US4310544A (es) |
| EP (1) | EP0009306B1 (es) |
| JP (2) | JPS5538384A (es) |
| AT (1) | ATE1855T1 (es) |
| AU (1) | AU522183B2 (es) |
| BE (2) | BE878594A (es) |
| CA (1) | CA1142542A (es) |
| CS (1) | CS212244B2 (es) |
| DD (1) | DD145747A5 (es) |
| DE (3) | DE2964097D1 (es) |
| DK (1) | DK369579A (es) |
| ES (2) | ES483977A1 (es) |
| FI (1) | FI792564A (es) |
| FR (2) | FR2468574A1 (es) |
| GB (1) | GB2031406B (es) |
| GR (1) | GR65651B (es) |
| IE (1) | IE48791B1 (es) |
| IL (1) | IL58074A (es) |
| IT (1) | IT1122501B (es) |
| NL (2) | NL7906339A (es) |
| NO (1) | NO792589L (es) |
| PH (1) | PH14631A (es) |
| PL (2) | PL124197B1 (es) |
| PT (1) | PT70146A (es) |
| SE (2) | SE7907311L (es) |
| ZA (1) | ZA794088B (es) |
| ZW (1) | ZW15179A1 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB2073178B (en) * | 1980-04-03 | 1984-01-25 | Ici Ltd | Dioxolane derivatives |
| FR2514355A1 (fr) * | 1981-10-14 | 1983-04-15 | Fabre Sa Pierre | Derives de biphenyl alcoyl carboxylates, leur procede de preparation et leur utilisation comme medicaments |
| US5789434A (en) * | 1994-11-15 | 1998-08-04 | Bayer Corporation | Derivatives of substituted 4-biarylbutyric acid as matrix metalloprotease inhibitors |
| HRP950558A2 (en) * | 1994-11-15 | 1997-12-31 | Scott M. Wilhelm | Substituted 4-biarylbutric or biarylpentanoic acids and derivatives as matrix metalloprotease inhibitors |
| JP2002516855A (ja) * | 1998-06-02 | 2002-06-11 | アースロミックス・パブリック・リミテッド・カンパニー | 繊維症治療用の甲状腺ホルモン受容体と相互作用する化合物 |
| US8742167B2 (en) * | 2008-01-11 | 2014-06-03 | Shanghai Institute Of Pharmaceutical Industry | Therapeutic formulations based on asiatic acid and selected salts thereof |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| GB1140748A (en) * | 1966-06-23 | 1969-01-22 | Ici Ltd | New carboxylic acid derivatives |
| DE2358789A1 (de) * | 1973-02-07 | 1975-06-05 | Merck Patent Gmbh | Hydratropasaeure-derivate und verfahren zu ihrer herstellung |
-
1979
- 1979-07-25 EP EP79301483A patent/EP0009306B1/en not_active Expired
- 1979-07-25 DE DE7979301483T patent/DE2964097D1/de not_active Expired
- 1979-07-25 AT AT79301483T patent/ATE1855T1/de not_active IP Right Cessation
- 1979-07-30 GB GB7926481A patent/GB2031406B/en not_active Expired
- 1979-08-06 GR GR59783A patent/GR65651B/el unknown
- 1979-08-07 CA CA000333277A patent/CA1142542A/en not_active Expired
- 1979-08-07 ZW ZW151/79A patent/ZW15179A1/xx unknown
- 1979-08-07 ZA ZA00794088A patent/ZA794088B/xx unknown
- 1979-08-08 IE IE1510/79A patent/IE48791B1/en unknown
- 1979-08-08 NO NO792589A patent/NO792589L/no unknown
- 1979-08-09 AU AU49753/79A patent/AU522183B2/en not_active Ceased
- 1979-08-13 PH PH22892A patent/PH14631A/en unknown
- 1979-08-17 FI FI792564A patent/FI792564A/fi not_active Application Discontinuation
- 1979-08-20 IL IL58074A patent/IL58074A/xx unknown
- 1979-08-21 IT IT25221/79A patent/IT1122501B/it active
- 1979-08-22 NL NL7906339A patent/NL7906339A/nl not_active Application Discontinuation
- 1979-08-24 DE DE19792934398 patent/DE2934398A1/de not_active Withdrawn
- 1979-08-24 DE DE19792934375 patent/DE2934375A1/de not_active Withdrawn
- 1979-08-27 PL PL1979227292A patent/PL124197B1/pl unknown
- 1979-08-27 PL PL1979217978A patent/PL117130B1/pl unknown
- 1979-08-31 NL NL7906554A patent/NL7906554A/nl not_active Application Discontinuation
- 1979-09-03 SE SE7907311A patent/SE7907311L/xx not_active Application Discontinuation
- 1979-09-04 BE BE0/197011A patent/BE878594A/fr not_active IP Right Cessation
- 1979-09-04 DK DK369579A patent/DK369579A/da not_active Application Discontinuation
- 1979-09-04 BE BE197012A patent/BE878595A/fr unknown
- 1979-09-05 SE SE7907390A patent/SE437262B/sv not_active IP Right Cessation
- 1979-09-05 CS CS796015A patent/CS212244B2/cs unknown
- 1979-09-05 PT PT70146A patent/PT70146A/pt unknown
- 1979-09-06 DD DD79215387A patent/DD145747A5/de unknown
- 1979-09-07 FR FR7922375A patent/FR2468574A1/fr active Granted
- 1979-09-07 ES ES483977A patent/ES483977A1/es not_active Expired
- 1979-09-07 FR FR7922374A patent/FR2468575A1/fr active Granted
- 1979-09-07 JP JP11437179A patent/JPS5538384A/ja active Pending
- 1979-09-07 ES ES483978A patent/ES483978A1/es not_active Expired
- 1979-09-07 JP JP11437279A patent/JPS5538385A/ja active Pending
-
1980
- 1980-10-31 US US06/203,225 patent/US4310544A/en not_active Expired - Lifetime
- 1980-12-29 US US06/220,718 patent/US4304788A/en not_active Expired - Fee Related
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