DE2964097D1 - Anti-arthritic hydroxyacetic acid derivatives, pharmaceutical compositions thereof, and processes for their manufacture - Google Patents

Anti-arthritic hydroxyacetic acid derivatives, pharmaceutical compositions thereof, and processes for their manufacture

Info

Publication number
DE2964097D1
DE2964097D1 DE7979301483T DE2964097T DE2964097D1 DE 2964097 D1 DE2964097 D1 DE 2964097D1 DE 7979301483 T DE7979301483 T DE 7979301483T DE 2964097 T DE2964097 T DE 2964097T DE 2964097 D1 DE2964097 D1 DE 2964097D1
Authority
DE
Germany
Prior art keywords
sup
arthritic
manufacture
processes
pharmaceutical compositions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
DE7979301483T
Other languages
English (en)
Inventor
Michael Derek Edge
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Imperial Chemical Industries Ltd
Original Assignee
Imperial Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Imperial Chemical Industries Ltd filed Critical Imperial Chemical Industries Ltd
Application granted granted Critical
Publication of DE2964097D1 publication Critical patent/DE2964097D1/de
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00—Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40—Unsaturated compounds
    • C07C59/58—Unsaturated compounds containing ether groups, groups, groups, or groups
    • C07C59/64—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings
    • C07C59/66—Unsaturated compounds containing ether groups, groups, groups, or groups containing six-membered aromatic rings the non-carboxylic part of the ether containing six-membered aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45—Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46—Friedel-Crafts reactions
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00—Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/367—Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in singly bound form

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DE7979301483T 1978-09-08 1979-07-25 Anti-arthritic hydroxyacetic acid derivatives, pharmaceutical compositions thereof, and processes for their manufacture Expired DE2964097D1 (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB7836173 1978-09-08

Publications (1)

Publication Number Publication Date
DE2964097D1 true DE2964097D1 (en) 1982-12-30

Family

ID=10499548

Family Applications (3)

Application Number Title Priority Date Filing Date
DE7979301483T Expired DE2964097D1 (en) 1978-09-08 1979-07-25 Anti-arthritic hydroxyacetic acid derivatives, pharmaceutical compositions thereof, and processes for their manufacture
DE19792934398 Withdrawn DE2934398A1 (de) 1978-09-08 1979-08-24 Hydroxyalkansaeurederivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen
DE19792934375 Withdrawn DE2934375A1 (de) 1978-09-08 1979-08-24 Hydroxyessigsaeurederivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen

Family Applications After (2)

Application Number Title Priority Date Filing Date
DE19792934398 Withdrawn DE2934398A1 (de) 1978-09-08 1979-08-24 Hydroxyalkansaeurederivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen
DE19792934375 Withdrawn DE2934375A1 (de) 1978-09-08 1979-08-24 Hydroxyessigsaeurederivate, verfahren zu ihrer herstellung und sie enthaltende pharmazeutische zusammensetzungen

Country Status (27)

Country Link
US (2) US4310544A (de)
EP (1) EP0009306B1 (de)
JP (2) JPS5538384A (de)
AT (1) ATE1855T1 (de)
AU (1) AU522183B2 (de)
BE (2) BE878594A (de)
CA (1) CA1142542A (de)
CS (1) CS212244B2 (de)
DD (1) DD145747A5 (de)
DE (3) DE2964097D1 (de)
DK (1) DK369579A (de)
ES (2) ES483977A1 (de)
FI (1) FI792564A (de)
FR (2) FR2468574A1 (de)
GB (1) GB2031406B (de)
GR (1) GR65651B (de)
IE (1) IE48791B1 (de)
IL (1) IL58074A (de)
IT (1) IT1122501B (de)
NL (2) NL7906339A (de)
NO (1) NO792589L (de)
PH (1) PH14631A (de)
PL (2) PL124197B1 (de)
PT (1) PT70146A (de)
SE (2) SE7907311L (de)
ZA (1) ZA794088B (de)
ZW (1) ZW15179A1 (de)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2073178B (en) * 1980-04-03 1984-01-25 Ici Ltd Dioxolane derivatives
FR2514355A1 (fr) * 1981-10-14 1983-04-15 Fabre Sa Pierre Derives de biphenyl alcoyl carboxylates, leur procede de preparation et leur utilisation comme medicaments
US5789434A (en) * 1994-11-15 1998-08-04 Bayer Corporation Derivatives of substituted 4-biarylbutyric acid as matrix metalloprotease inhibitors
HRP950558A2 (en) * 1994-11-15 1997-12-31 Scott M. Wilhelm Substituted 4-biarylbutric or biarylpentanoic acids and derivatives as matrix metalloprotease inhibitors
JP2002516855A (ja) * 1998-06-02 2002-06-11 アースロミックス・パブリック・リミテッド・カンパニー 繊維症治療用の甲状腺ホルモン受容体と相互作用する化合物
US8742167B2 (en) * 2008-01-11 2014-06-03 Shanghai Institute Of Pharmaceutical Industry Therapeutic formulations based on asiatic acid and selected salts thereof

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB1140748A (en) * 1966-06-23 1969-01-22 Ici Ltd New carboxylic acid derivatives
DE2358789A1 (de) * 1973-02-07 1975-06-05 Merck Patent Gmbh Hydratropasaeure-derivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
BE878595A (fr) 1980-03-04
FI792564A (fi) 1980-03-09
FR2468575B1 (de) 1983-02-18
FR2468574B1 (de) 1983-04-22
PL217978A1 (de) 1980-04-21
PH14631A (en) 1981-10-12
AU522183B2 (en) 1982-05-20
IL58074A (en) 1982-07-30
ATE1855T1 (de) 1982-12-15
IE48791B1 (en) 1985-05-15
IT1122501B (it) 1986-04-23
IT7925221A0 (it) 1979-08-21
GB2031406B (en) 1982-06-16
EP0009306B1 (de) 1982-11-24
SE7907311L (sv) 1980-03-09
PL124197B1 (en) 1982-12-31
DD145747A5 (de) 1981-01-07
GB2031406A (en) 1980-04-23
NO792589L (no) 1980-03-11
ES483978A1 (es) 1980-04-16
ES483977A1 (es) 1980-04-16
IL58074A0 (en) 1979-12-30
DK369579A (da) 1980-03-09
IE791510L (en) 1980-03-08
SE7907390L (sv) 1980-03-09
US4310544A (en) 1982-01-12
BE878594A (fr) 1980-03-04
CS212244B2 (en) 1982-03-26
AU4975379A (en) 1980-03-13
NL7906339A (nl) 1980-03-11
JPS5538384A (en) 1980-03-17
DE2934398A1 (de) 1980-06-12
US4304788A (en) 1981-12-08
DE2934375A1 (de) 1980-06-12
PL117130B1 (en) 1981-07-31
CA1142542A (en) 1983-03-08
NL7906554A (nl) 1980-03-11
JPS5538385A (en) 1980-03-17
FR2468574A1 (fr) 1981-05-08
ZW15179A1 (en) 1981-03-18
SE437262B (sv) 1985-02-18
FR2468575A1 (fr) 1981-05-08
GR65651B (en) 1980-10-16
PT70146A (en) 1979-10-01
ZA794088B (en) 1980-08-27
EP0009306A1 (de) 1980-04-02

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Legal Events

Date Code Title Description
8339 Ceased/non-payment of the annual fee