ES483511A1 - Un procedimiento para la preparaion de nuevas espiro-oxazo- lidinohoinas. - Google Patents
Un procedimiento para la preparaion de nuevas espiro-oxazo- lidinohoinas.Info
- Publication number
- ES483511A1 ES483511A1 ES483511A ES483511A ES483511A1 ES 483511 A1 ES483511 A1 ES 483511A1 ES 483511 A ES483511 A ES 483511A ES 483511 A ES483511 A ES 483511A ES 483511 A1 ES483511 A1 ES 483511A1
- Authority
- ES
- Spain
- Prior art keywords
- oxazolidindiones
- spiro
- disclosed
- diabetic complications
- chronic diabetic
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 208000002249 Diabetes Complications Diseases 0.000 abstract 2
- 206010012655 Diabetic complications Diseases 0.000 abstract 2
- 230000001684 chronic effect Effects 0.000 abstract 2
- 239000003288 aldose reductase inhibitor Substances 0.000 abstract 1
- 229940090865 aldose reductase inhibitors used in diabetes Drugs 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 229940124597 therapeutic agent Drugs 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D335/00—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom
- C07D335/04—Heterocyclic compounds containing six-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
- C07D335/06—Benzothiopyrans; Hydrogenated benzothiopyrans
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/22—Anxiolytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
- A61P27/12—Ophthalmic agents for cataracts
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P3/00—Drugs for disorders of the metabolism
- A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
- A61P3/10—Drugs for disorders of the metabolism for glucose homeostasis for hyperglycaemia, e.g. antidiabetics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
- C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
- C07D311/04—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring
- C07D311/22—Benzo[b]pyrans, not hydrogenated in the carbocyclic ring with oxygen or sulfur atoms directly attached in position 4
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F7/00—Compounds containing elements of Groups 4 or 14 of the Periodic Table
- C07F7/02—Silicon compounds
- C07F7/08—Compounds having one or more C—Si linkages
- C07F7/18—Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
- C07F7/1804—Compounds having Si-O-C linkages
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Life Sciences & Earth Sciences (AREA)
- Engineering & Computer Science (AREA)
- Diabetes (AREA)
- Ophthalmology & Optometry (AREA)
- Emergency Medicine (AREA)
- Endocrinology (AREA)
- Obesity (AREA)
- Hematology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Heterocyclic Compounds Containing Sulfur Atoms (AREA)
- Pyrane Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Photosensitive Polymer And Photoresist Processing (AREA)
- Moulding By Coating Moulds (AREA)
- Dental Preparations (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US05/935,199 US4200642A (en) | 1978-08-21 | 1978-08-21 | Spiro-oxazolidindiones |
Publications (1)
Publication Number | Publication Date |
---|---|
ES483511A1 true ES483511A1 (es) | 1980-09-01 |
Family
ID=25466700
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES483511A Expired ES483511A1 (es) | 1978-08-21 | 1979-08-20 | Un procedimiento para la preparaion de nuevas espiro-oxazo- lidinohoinas. |
Country Status (34)
Families Citing this family (27)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4329459A (en) * | 1980-05-05 | 1982-05-11 | The Upjohn Company | Tetrahydrobenzopyran derivatives |
GB2080803B (en) * | 1980-07-28 | 1984-01-18 | Pfizer | Hypoglycemic 5-substituted oxazolidine-2,4-diones |
US4367234A (en) * | 1980-07-28 | 1983-01-04 | Pfizer Inc. | Hypoglycemic 5-substituted oxazolidine-2,4-diones |
ES8400116A1 (es) * | 1981-10-13 | 1983-10-16 | Pfizer | "un procedimiento por analogia para la preparacion de derivados de espiro-oxindol-oxazolidindiona". |
US4540700A (en) * | 1982-04-15 | 1985-09-10 | Alcon Laboratories, Inc. | Treatment of diabetic complications with certain spiro-imidazolidine-diones |
US4438272A (en) | 1982-04-15 | 1984-03-20 | Alcon Laboratories, Inc. | Spiro-(fluoren-9,4'-imidazolidine)-2',5'-diones |
US4436745A (en) | 1982-04-15 | 1984-03-13 | Alcon Laboratories, Inc. | Method of inhibiting aldose reductase activity |
US4464385A (en) * | 1982-04-15 | 1984-08-07 | Alcon Laboratories, Inc. | Treatment of diabetic complications with hydantoins |
ZA832679B (en) * | 1982-05-07 | 1983-12-28 | Ici Plc | Indoline derivatives |
US4430337A (en) * | 1982-06-23 | 1984-02-07 | Pfizer Inc. | Alicyclic substituted oxazolidine-2,4-diones having hypoglycemic activity |
US4556670A (en) * | 1982-12-06 | 1985-12-03 | Pfizer Inc. | Spiro-3-hetero-azolones for treatment of diabetic complications |
US4464380A (en) * | 1983-05-25 | 1984-08-07 | Pfizer Inc. | Imidazolidinedione derivatives |
US4533667A (en) * | 1983-05-25 | 1985-08-06 | Pfizer Inc. | Imidazolidinedione derivatives |
DK277484A (da) * | 1983-06-23 | 1984-12-24 | Hoffmann La Roche | Thiazolidinderivater |
JPS61200991A (ja) * | 1985-03-04 | 1986-09-05 | Sanwa Kagaku Kenkyusho:Kk | スピロ―3―ヘテロアゾリジン化合物、その製法及びそれを有効成分とする糖尿病合併症の予防及び治療剤 |
DE3522791C1 (en) * | 1985-06-26 | 1987-01-02 | Ferroplast Gmbh | Positioning wall for lagging a cavity to be filled with a hardenable material in mining or tunnelling |
US4853410A (en) * | 1986-01-17 | 1989-08-01 | Pfizer Inc. | Hydroxyacetic acid derivatives for the treatment of diabetic complications |
US5039672A (en) * | 1990-04-05 | 1991-08-13 | Pfizer Inc. | Heterocyclic compounds as aldose reductase inhibitors |
US5068332A (en) * | 1990-10-12 | 1991-11-26 | American Home Products Corporation | Alkylidene analogs of 1'-aminospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrones useful as aldose reductase inhibitors |
US5102886A (en) * | 1990-10-12 | 1992-04-07 | American Home Products Corporation | 1'-aminospiro[isoquinoline-4(1H),3'-pyrrolidine]-1,2',3,5'(2H)-tetrones and analogs thereof useful as aldose reductase inhibitors |
FR2707981B1 (fr) * | 1993-07-20 | 1995-09-01 | Adir | Nouveaux dérivés de benzospiroalcène, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
CA2377246A1 (en) | 1999-06-18 | 2000-12-28 | Ranjit C. Desai | Arylthiazolidinedione and aryloxazolidinedione derivatives |
EP1194146B1 (en) | 1999-06-18 | 2006-07-19 | Merck & Co., Inc. | Arylthiazolidinedione and aryloxazolidinedione derivatives |
ITPI20060083A1 (it) * | 2006-07-11 | 2008-01-12 | Univ Pisa | Derivati 2,2-dimetilcromanici 4-spiro-eterocicilici azotati (a 5 e 6 termini) n-sostituiti quali cardio-protettori nei confronti dell'insulto ischemico |
USD775790S1 (en) * | 2015-11-18 | 2017-01-10 | Ginger Damon | Motorcycle jacket |
CN111246828B (zh) | 2017-12-21 | 2022-07-01 | 易希提卫生与保健公司 | 具有通道密封件的吸收性物品和制造吸收性物品的方法 |
CN111465377A (zh) | 2017-12-21 | 2020-07-28 | 易希提卫生与保健公司 | 包括强壮的通道密封结合的吸收性物品 |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE1204232B (de) * | 1959-07-16 | 1965-11-04 | Ncr Co | Verfahren zur Herstellung von Derivaten von 3-Alkyl-3'-methyl-spiro[benzoxazolin-2, 2'-(2'H-1'-benzopyran)] |
US3532744A (en) * | 1967-07-28 | 1970-10-06 | American Home Prod | 1- and 2-amino substituted indane and tetralene carboxylic acids |
US3821383A (en) * | 1972-07-10 | 1974-06-28 | Ayerst Mckenna & Harrison | Compositions for and a method of treating diabetic complications |
CA1088945A (en) * | 1976-10-18 | 1980-11-04 | Pfizer Limited | Hydantoin derivatives as therapeutic agents |
-
1978
- 1978-08-21 US US05/935,199 patent/US4200642A/en not_active Expired - Lifetime
-
1979
- 1979-06-20 DK DK258479A patent/DK258479A/da not_active Application Discontinuation
- 1979-06-21 IN IN451/DEL/79A patent/IN152416B/en unknown
- 1979-07-27 GB GB7926348A patent/GB2028318B/en not_active Expired
- 1979-08-16 YU YU1999/79A patent/YU41488B/xx unknown
- 1979-08-16 CH CH752879A patent/CH639974A5/fr not_active IP Right Cessation
- 1979-08-17 DE DE2953954A patent/DE2953954C2/de not_active Expired
- 1979-08-17 CA CA000333955A patent/CA1121361A/en not_active Expired
- 1979-08-17 HU HU79PI685A patent/HU179746B/hu unknown
- 1979-08-17 DE DE2933441A patent/DE2933441C2/de not_active Expired
- 1979-08-17 FI FI792567A patent/FI65255C/fi not_active IP Right Cessation
- 1979-08-18 JP JP54105459A patent/JPS6011914B2/ja not_active Expired
- 1979-08-20 IL IL58076A patent/IL58076A/xx unknown
- 1979-08-20 ES ES483511A patent/ES483511A1/es not_active Expired
- 1979-08-20 NZ NZ191350A patent/NZ191350A/en unknown
- 1979-08-20 LU LU81613A patent/LU81613A1/fr unknown
- 1979-08-20 SE SE7906949A patent/SE447116B/sv not_active IP Right Cessation
- 1979-08-20 AT AT0560579A patent/AT366689B/de not_active IP Right Cessation
- 1979-08-20 IT IT25182/79A patent/IT1123536B/it active
- 1979-08-20 EG EG79509A patent/EG14639A/xx active
- 1979-08-20 ZA ZA00794379A patent/ZA794379B/xx unknown
- 1979-08-20 IE IE1592/79A patent/IE48932B1/en not_active IP Right Cessation
- 1979-08-20 AU AU50092/79A patent/AU535170B2/en not_active Ceased
- 1979-08-20 SU SU792803649A patent/SU942597A3/ru active
- 1979-08-20 BE BE0/196785A patent/BE878311A/fr not_active IP Right Cessation
- 1979-08-20 PT PT70086A patent/PT70086A/pt unknown
- 1979-08-20 GR GR59870A patent/GR71913B/el unknown
- 1979-08-20 NO NO792699A patent/NO792699L/no unknown
- 1979-08-20 FR FR7920969A patent/FR2442851A1/fr active Granted
- 1979-08-21 PL PL1979217881A patent/PL130686B1/pl unknown
- 1979-08-21 PH PH22931A patent/PH18091A/en unknown
- 1979-08-21 DD DD79215099A patent/DD146602A5/de unknown
- 1979-08-21 NL NL7906318A patent/NL7906318A/nl active Search and Examination
- 1979-08-21 AR AR277784A patent/AR225614A1/es active
- 1979-08-21 CS CS795699A patent/CS208129B2/cs unknown
- 1979-08-27 GB GB8001161A patent/GB2033904B/en not_active Expired
- 1979-11-16 JP JP54148748A patent/JPS6011915B2/ja not_active Expired
- 1979-11-16 JP JP54148747A patent/JPS5946517B2/ja not_active Expired
- 1979-11-16 JP JP54148749A patent/JPS5943954B2/ja not_active Expired
-
1980
- 1980-02-07 FR FR8002697A patent/FR2440949A1/fr active Granted
- 1980-02-07 FR FR8002698A patent/FR2440950A1/fr active Granted
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
MM4A | Patent lapsed |
Effective date: 19960506 |