ES475328A1 - Procedimiento de preparacion de nuevas indol (2,3-a)quinoli-zidinas - Google Patents
Procedimiento de preparacion de nuevas indol (2,3-a)quinoli-zidinasInfo
- Publication number
- ES475328A1 ES475328A1 ES475328A ES475328A ES475328A1 ES 475328 A1 ES475328 A1 ES 475328A1 ES 475328 A ES475328 A ES 475328A ES 475328 A ES475328 A ES 475328A ES 475328 A1 ES475328 A1 ES 475328A1
- Authority
- ES
- Spain
- Prior art keywords
- quinolizidines
- indolo
- preparation
- therapeutic use
- new
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 230000001225 therapeutic effect Effects 0.000 title 1
- IJGRMHOSHXDMSA-UHFFFAOYSA-N Atomic nitrogen Chemical compound N#N IJGRMHOSHXDMSA-UHFFFAOYSA-N 0.000 abstract 2
- OURDZMSSMGUMKR-UHFFFAOYSA-N 1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a]quinolizine Chemical class C1=CC=C2C(CCN3CCCCC33)=C3NC2=C1 OURDZMSSMGUMKR-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000004519 manufacturing process Methods 0.000 abstract 1
- 229910052757 nitrogen Inorganic materials 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
- C07D471/14—Ortho-condensed systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Cardiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Heart & Thoracic Surgery (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Indole Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB4920177 | 1977-11-25 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES475328A1 true ES475328A1 (es) | 1979-04-01 |
Family
ID=10451538
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES475328A Expired ES475328A1 (es) | 1977-11-25 | 1978-11-23 | Procedimiento de preparacion de nuevas indol (2,3-a)quinoli-zidinas |
Country Status (28)
| Country | Link |
|---|---|
| JP (1) | JPS6147838B2 (en, 2012) |
| AR (1) | AR218514A1 (en, 2012) |
| AT (1) | AT372384B (en, 2012) |
| AU (1) | AU529108B2 (en, 2012) |
| BE (1) | BE872134A (en, 2012) |
| CA (1) | CA1100959A (en, 2012) |
| CH (1) | CH641181A5 (en, 2012) |
| DE (1) | DE2851028A1 (en, 2012) |
| DK (1) | DK154430C (en, 2012) |
| EG (1) | EG13683A (en, 2012) |
| ES (1) | ES475328A1 (en, 2012) |
| FI (1) | FI64372C (en, 2012) |
| FR (2) | FR2423492A1 (en, 2012) |
| HK (1) | HK60884A (en, 2012) |
| IE (1) | IE47518B1 (en, 2012) |
| IN (1) | IN151146B (en, 2012) |
| IT (1) | IT1160263B (en, 2012) |
| LU (1) | LU80576A1 (en, 2012) |
| MX (1) | MX5529E (en, 2012) |
| MY (1) | MY8500029A (en, 2012) |
| NL (1) | NL7811562A (en, 2012) |
| NO (1) | NO151288C (en, 2012) |
| NZ (1) | NZ188974A (en, 2012) |
| PT (1) | PT68825A (en, 2012) |
| SE (2) | SE431650B (en, 2012) |
| SG (1) | SG61182G (en, 2012) |
| WO (1) | WO1979000319A1 (en, 2012) |
| ZA (1) | ZA786426B (en, 2012) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0079411B1 (fr) * | 1981-11-18 | 1987-02-04 | Thal, Claude | Dérivés d'indoloquinolizine, leur procédé de préparation et leur application en thérapeutique |
| FR2529552B1 (fr) * | 1982-07-05 | 1985-09-27 | Centre Nat Rech Scient | Nouveau procede de preparation d'intermediaires de synthese de la vindoline et intermediaires de synthese |
| HU191454B (en) * | 1984-10-05 | 1987-02-27 | Richter Gedeon Vegyeszeti Gyar Rt.,Hu | Process for producing amides of oktahydro-indolo/2,3-a/quinolyzin-1-yl-alkanecarboxylic acids and pharmaceutically acceptable acid additional salts thereof |
| HU194220B (en) * | 1985-04-19 | 1988-01-28 | Richter Gedeon Vegyeszet | Process for production of derivatives of 1,12 b disubstituated-octahydro-indolo /2,3-a/ quinolisine and medical compounds containing thereof |
| HU195214B (en) * | 1985-04-19 | 1988-04-28 | Richter Gedeon Vegyeszet | Process for producing 12b-substituted-1-(hydroxymethyl)-octahydro-indolo /2,3-a/ quinolizine derivatives and pharmaceutical preparations comprising these compounds |
| FI95572C (fi) | 1987-06-22 | 1996-02-26 | Eisai Co Ltd | Menetelmä lääkeaineena käyttökelpoisen piperidiinijohdannaisten tai sen farmaseuttisen suolan valmistamiseksi |
| JP3489116B2 (ja) * | 1993-06-18 | 2004-01-19 | 藤沢薬品工業株式会社 | 新規合成中間体およびアミノピペラジン誘導体の製造法 |
| FR2713643B1 (fr) * | 1993-12-14 | 1996-06-07 | Adir | Nouveaux analogues de l'éburnane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
| FR2713644B1 (fr) * | 1993-12-14 | 1996-02-09 | Adir | Nouveaux analogues de l'éburnane, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent. |
| AU2003260599A1 (en) † | 2002-06-24 | 2004-01-06 | Saint-Gobain Isover | Insulation panel for supply duct |
| FR2911141B1 (fr) * | 2007-01-05 | 2009-02-20 | Servier Lab | Nouveaux derives triazabenzo[a]naphtho[2,1,8-cde]azulene, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| FR2911143A1 (fr) * | 2007-01-05 | 2008-07-11 | Servier Lab | Utilisation de composes neuroprotecteurs pour l'obtention de medicaments destines au traitement de maladies neurodegeneratives. |
| FR2911142A1 (fr) * | 2007-01-05 | 2008-07-11 | Servier Lab | Nouveaux derives aminopyrrolo[1,2-a]indole et aminopyridazino[1,6-a]indole,leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| USD685271S1 (en) | 2012-04-04 | 2013-07-02 | Colgate-Palmolive Company | Container |
| USD685269S1 (en) | 2012-04-04 | 2013-07-02 | Colgate-Palmolive Company | Container |
| USD685270S1 (en) | 2012-04-04 | 2013-07-02 | Colgate-Palmolive Company | Container |
| USD688951S1 (en) | 2012-04-04 | 2013-09-03 | Colgate-Palmolive Company | Container |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU167366B (en, 2012) * | 1972-09-06 | 1975-09-27 | ||
| BE802387A (fr) * | 1973-07-16 | 1973-11-16 | Omnium Chimique Sa | Procede de preparation de la vincamone et de l'epi-21 vincamone a partir de la tabersonine et derives indoliques nouveaux. |
| HU169916B (en, 2012) * | 1974-09-27 | 1977-02-28 | ||
| HU171165B (hu) * | 1974-11-26 | 1977-11-28 | Richter Gedeon Vegyeszet | Sposob poluchenija proizvodnykh oktagidro-indolo-skobka-2,3-a-skobka zakryta-kinolizina |
| FR2315277A1 (fr) * | 1975-06-25 | 1977-01-21 | Anvar | Nouveaux derives pentacycliques, leur preparation et les compositions qui les contiennent |
-
1978
- 1978-11-15 ZA ZA00786426A patent/ZA786426B/xx unknown
- 1978-11-20 BE BE191824A patent/BE872134A/xx not_active IP Right Cessation
- 1978-11-22 NZ NZ188974A patent/NZ188974A/xx unknown
- 1978-11-23 NO NO783958A patent/NO151288C/no unknown
- 1978-11-23 AU AU41874/78A patent/AU529108B2/en not_active Expired
- 1978-11-23 AT AT0837478A patent/AT372384B/de active
- 1978-11-23 ES ES475328A patent/ES475328A1/es not_active Expired
- 1978-11-23 PT PT68825A patent/PT68825A/pt unknown
- 1978-11-23 FI FI783581A patent/FI64372C/fi not_active IP Right Cessation
- 1978-11-23 AR AR274552A patent/AR218514A1/es active
- 1978-11-24 FR FR7833175A patent/FR2423492A1/fr active Granted
- 1978-11-24 IN IN851/DEL/78A patent/IN151146B/en unknown
- 1978-11-24 NL NL7811562A patent/NL7811562A/xx not_active Application Discontinuation
- 1978-11-24 JP JP54500118A patent/JPS6147838B2/ja not_active Expired
- 1978-11-24 WO PCT/FR1978/000043 patent/WO1979000319A1/fr unknown
- 1978-11-24 FR FR7833176A patent/FR2409755A1/fr active Granted
- 1978-11-24 CH CH683579A patent/CH641181A5/fr not_active IP Right Cessation
- 1978-11-24 IT IT30171/78A patent/IT1160263B/it active
- 1978-11-24 DK DK524978A patent/DK154430C/da not_active IP Right Cessation
- 1978-11-24 IE IE2328/78A patent/IE47518B1/en unknown
- 1978-11-24 CA CA316,809A patent/CA1100959A/en not_active Expired
- 1978-11-24 LU LU80576A patent/LU80576A1/xx unknown
- 1978-11-24 DE DE19782851028 patent/DE2851028A1/de active Granted
- 1978-11-24 MX MX787557U patent/MX5529E/es unknown
- 1978-11-25 EG EG669/78A patent/EG13683A/xx active
-
1979
- 1979-07-23 SE SE7906287A patent/SE431650B/sv not_active IP Right Cessation
-
1980
- 1980-11-07 SE SE8007845A patent/SE435622B/sv not_active IP Right Cessation
-
1982
- 1982-12-03 SG SG611/82A patent/SG61182G/en unknown
-
1984
- 1984-08-02 HK HK608/84A patent/HK60884A/xx unknown
-
1985
- 1985-12-30 MY MY29/85A patent/MY8500029A/xx unknown
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19990201 |