ES470296A1 - Mejoras introducidas en un procedimiento para la preparacionde fluormetal-aminoacidos - Google Patents

Mejoras introducidas en un procedimiento para la preparacionde fluormetal-aminoacidos

Info

Publication number
ES470296A1
ES470296A1 ES470296A ES470296A ES470296A1 ES 470296 A1 ES470296 A1 ES 470296A1 ES 470296 A ES470296 A ES 470296A ES 470296 A ES470296 A ES 470296A ES 470296 A1 ES470296 A1 ES 470296A1
Authority
ES
Spain
Prior art keywords
compounds
amino acids
acid addition
addition salts
alpha
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES470296A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Merck and Co Inc
Original Assignee
Merck and Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/802,391 external-priority patent/US4325961A/en
Application filed by Merck and Co Inc filed Critical Merck and Co Inc
Publication of ES470296A1 publication Critical patent/ES470296A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
ES470296A 1977-06-01 1978-05-29 Mejoras introducidas en un procedimiento para la preparacionde fluormetal-aminoacidos Expired ES470296A1 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US80238977A 1977-06-01 1977-06-01
US05/802,391 US4325961A (en) 1977-06-01 1977-06-01 Fluorinated amino acids

Publications (1)

Publication Number Publication Date
ES470296A1 true ES470296A1 (es) 1979-09-16

Family

ID=27122442

Family Applications (1)

Application Number Title Priority Date Filing Date
ES470296A Expired ES470296A1 (es) 1977-06-01 1978-05-29 Mejoras introducidas en un procedimiento para la preparacionde fluormetal-aminoacidos

Country Status (26)

Country Link
JP (1) JPS5416423A (fi)
AR (1) AR223463A1 (fi)
AT (1) AT360509B (fi)
AU (1) AU518479B2 (fi)
CA (1) CA1120040A (fi)
CH (1) CH639639A5 (fi)
DD (1) DD138651A5 (fi)
DE (1) DE2824116A1 (fi)
DK (1) DK149841C (fi)
ES (1) ES470296A1 (fi)
FI (1) FI66840C (fi)
FR (1) FR2392958A1 (fi)
GB (1) GB1602525A (fi)
GR (1) GR64495B (fi)
HK (1) HK18184A (fi)
HU (1) HU181911B (fi)
IE (1) IE46983B1 (fi)
IT (1) IT1104709B (fi)
LU (1) LU79750A1 (fi)
NL (1) NL190485C (fi)
NO (1) NO147382C (fi)
NZ (1) NZ187377A (fi)
PL (1) PL115731B1 (fi)
PT (1) PT68102B (fi)
SE (1) SE7806440L (fi)
YU (1) YU129178A (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL59481A0 (en) * 1977-07-11 1980-05-30 Merrell Toraude & Co -halomethyl amino acids
CA1091661A (en) * 1977-07-11 1980-12-16 Philippe Bey .alpha.-HALOMETHYL DERIVATIVES OF .alpha.-AMINO ACIDS
ZA783273B (en) * 1977-07-11 1979-06-27 Merrell Toraude & Co A-halomethyl amino acids
US4315095A (en) * 1977-07-28 1982-02-09 Merrell Toraude Et Compagnie α-Halomethyl derivatives of amino acids
ATE3282T1 (de) * 1978-07-24 1983-05-15 Merck & Co. Inc. Alpha-difluormethyl-alpha-aminosaeuren und sie enthaltende pharmazeutische zusammensetzung.
IE49522B1 (en) * 1979-04-26 1985-10-16 Merrell Toraude & Co Alpha-halomethylaminoacids
CA1158657A (en) * 1979-07-26 1983-12-13 Philippe Bey Preparation of fluorinated methyl aminoalkanoic acids and novel process intermediates
ZA813018B (en) * 1980-05-09 1982-05-26 Merrell Toraude & Co Fluoromethylated tyrosine methyl ester
ZA813953B (en) * 1980-06-16 1982-06-30 Merrell Dow Pharma Method of inhibiting the growth of protozoa
US4421767A (en) * 1981-06-01 1983-12-20 Merrell Toraude Et Compagnie Compounds and methods for treating depression
GB9325368D0 (en) * 1993-12-10 1994-02-16 Univ Bristol Organic compounds

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3046300A (en) * 1960-10-21 1962-07-24 Merck & Co Inc alpha-trifluoromethyloxyphenylalanines

Also Published As

Publication number Publication date
FR2392958A1 (fr) 1978-12-29
AU518479B2 (en) 1981-10-01
LU79750A1 (fr) 1979-02-02
IT1104709B (it) 1985-10-28
DD138651A5 (de) 1979-11-14
AR223463A1 (es) 1981-08-31
AT360509B (de) 1981-01-12
DK149841B (da) 1986-10-13
PT68102B (en) 1982-06-08
CA1120040A (en) 1982-03-16
YU129178A (en) 1983-01-21
NO147382C (no) 1983-03-30
AU3658678A (en) 1979-12-06
GB1602525A (en) 1981-11-11
NO781892L (no) 1978-12-04
DK237978A (da) 1979-01-19
NO147382B (no) 1982-12-20
PL207242A1 (pl) 1979-04-23
IE46983B1 (en) 1983-11-16
PT68102A (en) 1978-06-01
IE781078L (en) 1978-12-01
FI781674A (fi) 1978-12-02
GR64495B (en) 1980-03-31
FI66840C (fi) 1984-12-10
NL190485B (nl) 1993-10-18
PL115731B1 (en) 1981-04-30
FI66840B (fi) 1984-08-31
ATA393278A (de) 1980-06-15
CH639639A5 (en) 1983-11-30
JPS641474B2 (fi) 1989-01-11
NL7805981A (nl) 1978-12-05
NL190485C (nl) 1994-03-16
DK149841C (da) 1987-04-21
HK18184A (en) 1984-03-09
HU181911B (en) 1983-11-28
JPS5416423A (en) 1979-02-07
DE2824116A1 (de) 1978-12-14
SE7806440L (sv) 1978-12-02
NZ187377A (en) 1981-05-15
IT7849637A0 (it) 1978-05-31
DE2824116C2 (fi) 1989-04-27
FR2392958B1 (fi) 1980-10-24

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19980202