ES469895A1 - Procedimiento para la obtencion de derivados de alquilendia-mina - Google Patents
Procedimiento para la obtencion de derivados de alquilendia-minaInfo
- Publication number
- ES469895A1 ES469895A1 ES469895A ES469895A ES469895A1 ES 469895 A1 ES469895 A1 ES 469895A1 ES 469895 A ES469895 A ES 469895A ES 469895 A ES469895 A ES 469895A ES 469895 A1 ES469895 A1 ES 469895A1
- Authority
- ES
- Spain
- Prior art keywords
- sub
- radical
- dioxopyrimidyl
- aryloxypropyl
- alkylenediamines
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired
Links
- 229910052739 hydrogen Inorganic materials 0.000 abstract 2
- 239000001257 hydrogen Substances 0.000 abstract 2
- 125000004214 1-pyrrolidinyl group Chemical group [H]C1([H])N(*)C([H])([H])C([H])([H])C1([H])[H] 0.000 abstract 1
- UFHFLCQGNIYNRP-UHFFFAOYSA-N Hydrogen Chemical compound [H][H] UFHFLCQGNIYNRP-UHFFFAOYSA-N 0.000 abstract 1
- 239000002253 acid Substances 0.000 abstract 1
- 125000004442 acylamino group Chemical group 0.000 abstract 1
- 125000003342 alkenyl group Chemical group 0.000 abstract 1
- 125000004183 alkoxy alkyl group Chemical group 0.000 abstract 1
- 125000003545 alkoxy group Chemical group 0.000 abstract 1
- 125000005083 alkoxyalkoxy group Chemical group 0.000 abstract 1
- 125000000217 alkyl group Chemical group 0.000 abstract 1
- 125000005263 alkylenediamine group Chemical group 0.000 abstract 1
- 125000000304 alkynyl group Chemical group 0.000 abstract 1
- 125000005133 alkynyloxy group Chemical group 0.000 abstract 1
- 125000001589 carboacyl group Chemical group 0.000 abstract 1
- 125000000392 cycloalkenyl group Chemical group 0.000 abstract 1
- 125000000000 cycloalkoxy group Chemical group 0.000 abstract 1
- 125000000753 cycloalkyl group Chemical group 0.000 abstract 1
- 229910052736 halogen Inorganic materials 0.000 abstract 1
- 150000002367 halogens Chemical class 0.000 abstract 1
- 150000002431 hydrogen Chemical class 0.000 abstract 1
- 125000002887 hydroxy group Chemical group [H]O* 0.000 abstract 1
- 125000005113 hydroxyalkoxy group Chemical group 0.000 abstract 1
- -1 morpholino, piperidino Chemical group 0.000 abstract 1
- 125000000449 nitro group Chemical group [O-][N+](*)=O 0.000 abstract 1
- 125000001997 phenyl group Chemical group [H]C1=C([H])C([H])=C(*)C([H])=C1[H] 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 125000002023 trifluoromethyl group Chemical group FC(F)(F)* 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/02—Drugs for disorders of the nervous system for peripheral neuropathies
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/06—Antiarrhythmics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Heart & Thoracic Surgery (AREA)
- Cardiology (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Neurosurgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Hydrogenated Pyridines (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| LU77339A LU77339A1 (GUID-C5D7CC26-194C-43D0-91A1-9AE8C70A9BFF.html) | 1977-05-16 | 1977-05-16 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| ES469895A1 true ES469895A1 (es) | 1979-09-16 |
Family
ID=19728575
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| ES469895A Expired ES469895A1 (es) | 1977-05-16 | 1978-05-16 | Procedimiento para la obtencion de derivados de alquilendia-mina |
Country Status (30)
Families Citing this family (16)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3023369A1 (de) * | 1980-06-23 | 1982-01-14 | Boehringer Mannheim Gmbh, 6800 Mannheim | Aryloxypropanolamine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| DE3048487A1 (de) * | 1980-12-22 | 1982-07-29 | Cassella Ag, 6000 Frankfurt | Basisch substituierte pyridazine, ihre herstellung und ihre verwendung |
| DE3131146A1 (de) * | 1981-08-06 | 1983-02-24 | Boehringer Mannheim Gmbh, 6800 Mannheim | Neue heteroaryloxypropanolamine, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel |
| JPS59225170A (ja) * | 1983-06-07 | 1984-12-18 | Mitsui Toatsu Chem Inc | アミノプロパノ−ル誘導体、その製造法、および該化合物を含有する心臓選択性β−アドレナリン作用遮断剤 |
| JPH0637479B2 (ja) * | 1987-12-28 | 1994-05-18 | 三井東圧化学株式会社 | 新規ピリミジン誘導体、その製造法およびそれを含有する抗不整脈剤 |
| US5008267A (en) * | 1988-10-29 | 1991-04-16 | Mitsui Toatsu Chemicals, Incorporated | Pyrimidinedione compounds, method of producing the same and antiarrythmic agents containing the same |
| US5308848A (en) * | 1989-10-24 | 1994-05-03 | Mitsui Toatsu Chemicals, Incorporated | Pyrimidinedione derivatives and antiarrythmic agents containing the same |
| JP2815218B2 (ja) * | 1990-04-13 | 1998-10-27 | 三井化学株式会社 | ピリミジンジオン誘導体、およびそれを含有する抗不整脈剤 |
| JPH03173885A (ja) * | 1989-12-01 | 1991-07-29 | Mitsui Toatsu Chem Inc | ピリミジンジオン誘導体化合物、該化合物の製造法および該化合物を含む抗不整脈剤 |
| JPH0413669A (ja) * | 1990-04-27 | 1992-01-17 | Mitsui Toatsu Chem Inc | 新規ピリミジンジオン誘導体及び該化合物を含有する抗不整脈剤 |
| DE4035599A1 (de) * | 1990-11-06 | 1992-05-07 | Dresden Arzneimittel | Neue 5-(phenoxyalkanoylamino)-uracile, verfahren zu ihrer herstellung und ihre verwendung als arzneimittel |
| EP1387673B1 (en) | 2001-05-11 | 2010-12-29 | Endo Pharmaceuticals Inc. | Abuse-resistant controlled-release opioid dosage form |
| DK2425821T5 (en) | 2002-04-05 | 2018-02-12 | Mundipharma As | Pharmaceutical preparation containing oxycodone and naloxone |
| EP1702558A1 (en) | 2005-02-28 | 2006-09-20 | Euro-Celtique S.A. | Method and device for the assessment of bowel function |
| AU2010223323B2 (en) | 2009-03-10 | 2013-07-04 | Euro-Celtique S.A. | Immediate release pharmaceutical compositions comprising oxycodone and naloxone |
| US10071089B2 (en) | 2013-07-23 | 2018-09-11 | Euro-Celtique S.A. | Combination of oxycodone and naloxone for use in treating pain in patients suffering from pain and a disease resulting in intestinal dysbiosis and/or increasing the risk for intestinal bacterial translocation |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| BE787103A (fr) * | 1971-08-04 | 1973-02-02 | Pfizer | Nouveaux derives de propanolamine et composition pharmaceutiqueles contenant |
| US4020071A (en) * | 1973-12-20 | 1977-04-26 | Cassella Farbwerke Mainkur Aktiengesellschaft | Derivatives of 1-phenoxy-3-amino-propan-2-ol |
-
1977
- 1977-05-16 LU LU77339A patent/LU77339A1/xx unknown
-
1978
- 1978-05-02 US US05/902,000 patent/US4216314A/en not_active Expired - Lifetime
- 1978-05-05 DE DE19782819629 patent/DE2819629A1/de not_active Withdrawn
- 1978-05-09 FI FI781461A patent/FI781461A7/fi not_active Application Discontinuation
- 1978-05-09 NO NO78781635A patent/NO781635L/no unknown
- 1978-05-09 NL NL7804966A patent/NL7804966A/xx not_active Application Discontinuation
- 1978-05-09 BG BG039701A patent/BG28699A3/xx unknown
- 1978-05-09 SE SE7805260A patent/SE7805260L/xx unknown
- 1978-05-09 BG BG039702A patent/BG28700A3/xx unknown
- 1978-05-09 DK DK203078A patent/DK203078A/da unknown
- 1978-05-11 AT AT343078A patent/AT359523B/de not_active IP Right Cessation
- 1978-05-11 AT AT342978A patent/AT359522B/de not_active IP Right Cessation
- 1978-05-12 DD DD78205363A patent/DD135489A5/xx unknown
- 1978-05-15 RO RO7894078A patent/RO75870A/ro unknown
- 1978-05-15 PL PL1978215183A patent/PL113674B1/pl unknown
- 1978-05-15 PT PT68044A patent/PT68044B/pt unknown
- 1978-05-15 ZA ZA00782758A patent/ZA782758B/xx unknown
- 1978-05-15 CA CA303,380A patent/CA1085842A/en not_active Expired
- 1978-05-15 AU AU36105/78A patent/AU3610578A/en active Pending
- 1978-05-15 GB GB19535/78A patent/GB1583428A/en not_active Expired
- 1978-05-15 SU SU782614700A patent/SU793389A3/ru active
- 1978-05-15 IT IT7823416A patent/IT1158712B/it active
- 1978-05-15 NZ NZ187272A patent/NZ187272A/xx unknown
- 1978-05-15 PL PL1978206810A patent/PL113762B1/pl unknown
- 1978-05-15 EG EG307/78A patent/EG13302A/xx active
- 1978-05-15 IE IE971/78A patent/IE46895B1/en unknown
- 1978-05-15 JP JP5670378A patent/JPS53141285A/ja active Pending
- 1978-05-16 GR GR56240A patent/GR71668B/el unknown
- 1978-05-16 CS CS783148A patent/CS203005B2/cs unknown
- 1978-05-16 FR FR7814387A patent/FR2391199A1/fr active Granted
- 1978-05-16 ES ES469895A patent/ES469895A1/es not_active Expired
- 1978-05-16 BE BE187732A patent/BE867116A/xx not_active IP Right Cessation
-
1979
- 1979-02-14 SU SU792723299A patent/SU841587A3/ru active
- 1979-08-24 AR AR277849A patent/AR224251A1/es active
Also Published As
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FD1A | Patent lapsed |
Effective date: 19990405 |