ES465861A1 - Procedimiento de preparacion de 4-difenilmetilen-1-hidroxi- bencil-piperidinas. - Google Patents

Procedimiento de preparacion de 4-difenilmetilen-1-hidroxi- bencil-piperidinas.

Info

Publication number
ES465861A1
ES465861A1 ES465861A ES465861A ES465861A1 ES 465861 A1 ES465861 A1 ES 465861A1 ES 465861 A ES465861 A ES 465861A ES 465861 A ES465861 A ES 465861A ES 465861 A1 ES465861 A1 ES 465861A1
Authority
ES
Spain
Prior art keywords
piperidine derivatives
halomethyloalkyl
a1a2a3
piperidines
addiction
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES465861A
Other languages
English (en)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
UCB SA
Original Assignee
UCB SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UCB SA filed Critical UCB SA
Publication of ES465861A1 publication Critical patent/ES465861A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28—Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/30—Oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/08—Vasodilators for multiple indications
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D211/00—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings
    • C07D211/04—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D211/68—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member
    • C07D211/70—Heterocyclic compounds containing hydrogenated pyridine rings, not condensed with other rings with only hydrogen or carbon atoms directly attached to the ring nitrogen atom having one double bond between ring members or between a ring member and a non-ring member with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms

Abstract

Procedimiento de preparación de 4-difenil-metilen-1-hidroxibencil-piperidinas de fórmula general***(ver fórmula I)en la que A1A2A3 y A4 representan independientemente unos de otrosun átomo de hidrógeno o halógenoun radical halometiloalcohilo o alcoxiy sus sales de adicción de ácidos farmacéuticamente aceptables.
ES465861A 1977-01-11 1978-01-10 Procedimiento de preparacion de 4-difenilmetilen-1-hidroxi- bencil-piperidinas. Expired ES465861A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB931/77A GB1542823A (en) 1977-01-11 1977-01-11 Piperidine derivatives

Publications (1)

Publication Number Publication Date
ES465861A1 true ES465861A1 (es) 1978-09-16

Family

ID=9713045

Family Applications (1)

Application Number Title Priority Date Filing Date
ES465861A Expired ES465861A1 (es) 1977-01-11 1978-01-10 Procedimiento de preparacion de 4-difenilmetilen-1-hidroxi- bencil-piperidinas.

Country Status (22)

Country Link
JP (1) JPS5387367A (es)
BE (1) BE862769A (es)
BG (1) BG28574A3 (es)
CA (1) CA1101426A (es)
CS (1) CS195652B2 (es)
DD (1) DD134089A5 (es)
DE (1) DE2800919A1 (es)
DK (1) DK5778A (es)
ES (1) ES465861A1 (es)
FI (1) FI780028A (es)
FR (1) FR2376846A1 (es)
GB (1) GB1542823A (es)
IL (1) IL53766A0 (es)
IT (1) IT1103117B (es)
LU (1) LU78839A1 (es)
NL (1) NL7800146A (es)
NO (1) NO780040L (es)
PL (1) PL203912A1 (es)
PT (1) PT67511B (es)
SE (1) SE7800184L (es)
SU (2) SU772482A3 (es)
ZA (1) ZA78158B (es)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4650874A (en) * 1984-11-26 1987-03-17 G. D. Searle & Co. N-(aralkoxybenzyl)-4(benzhydryl) piperidines
US4628095A (en) * 1985-06-05 1986-12-09 G. D. Searle & Co. Substituted N-benzyl-4-(benzhydryl) piperidines
EP0228893A3 (en) * 1985-12-20 1990-01-03 A.H. ROBINS COMPANY, INCORPORATED (a Delaware corporation) Arylalkyl-heterocyclic amines, n-substituted by aryloxyalkyl group in allergy treatment
GB9000305D0 (en) * 1990-01-06 1990-03-07 Pfizer Ltd Anticholinergic agents
WO1997022583A1 (de) * 1995-12-20 1997-06-26 Eckhart Pein Neue 1-phenylalkyl/alkylen-4-(.alpha.-hydroxydiphenylmethyl)-piperidin derivate und ihre verwendung als serotonin antagonisten
DE69924467T2 (de) * 1998-01-16 2006-02-16 Eisai Co., Ltd. Verfahren zur herstellung von donepezilderivaten
KR20050085673A (ko) * 2002-12-18 2005-08-29 에프엠씨 코포레이션 Ｎ-(치환된 아릴메틸)-4-(이치환된 메틸)피페리딘 및피페라진
WO2004103972A1 (ja) * 2003-05-20 2004-12-02 Ajinomoto Co.,Inc. 新規ピペリジン誘導体

Also Published As

Publication number Publication date
NO780040L (no) 1978-07-12
SE7800184L (sv) 1978-07-12
IT7847573A0 (it) 1978-01-10
IL53766A0 (en) 1978-04-30
CS195652B2 (en) 1980-02-29
PT67511A (fr) 1978-02-01
LU78839A1 (fr) 1978-09-18
ZA78158B (en) 1978-10-25
PL203912A1 (pl) 1979-06-04
NL7800146A (nl) 1978-07-13
CA1101426A (en) 1981-05-19
PT67511B (fr) 1979-06-11
SU990761A1 (ru) 1983-01-23
BE862769A (fr) 1978-07-10
DD134089A5 (de) 1979-02-07
JPS5387367A (en) 1978-08-01
BG28574A3 (en) 1980-05-15
JPS6125031B2 (es) 1986-06-13
FI780028A (fi) 1978-07-12
DE2800919A1 (de) 1978-07-13
DK5778A (da) 1978-07-12
IT1103117B (it) 1985-10-14
GB1542823A (en) 1979-03-28
SU772482A3 (ru) 1980-10-15
FR2376846A1 (fr) 1978-08-04
FR2376846B1 (es) 1983-02-04

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