ES468578A1 - Un procedimiento para la preparacion de derivados del acido fenilacetico cicloalcano-sustituidos - Google Patents

Un procedimiento para la preparacion de derivados del acido fenilacetico cicloalcano-sustituidos

Info

Publication number
ES468578A1
ES468578A1 ES468578A ES468578A ES468578A1 ES 468578 A1 ES468578 A1 ES 468578A1 ES 468578 A ES468578 A ES 468578A ES 468578 A ES468578 A ES 468578A ES 468578 A1 ES468578 A1 ES 468578A1
Authority
ES
Spain
Prior art keywords
phenylacetic acid
ylmethyl
hydrolyzing
reacting
preparation
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES468578A
Other languages
English (en)
Spanish (es)
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Sankyo Co Ltd
Original Assignee
Sankyo Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from JP3890677A external-priority patent/JPS584699B2/ja
Priority claimed from JP3890777A external-priority patent/JPS6034539B2/ja
Priority claimed from JP6846877A external-priority patent/JPS6034540B2/ja
Application filed by Sankyo Co Ltd filed Critical Sankyo Co Ltd
Publication of ES468578A1 publication Critical patent/ES468578A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C279/00—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups
    • C07C279/04—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton
    • C07C279/14—Derivatives of guanidine, i.e. compounds containing the group, the singly-bound nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of guanidine groups bound to acyclic carbon atoms of a carbon skeleton being further substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
    • C07C251/32—Oximes
    • C07C251/50—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals
    • C07C251/60—Oximes having oxygen atoms of oxyimino groups bound to carbon atoms of substituted hydrocarbon radicals of hydrocarbon radicals substituted by carboxyl groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C57/00—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms
    • C07C57/46—Unsaturated compounds having carboxyl groups bound to acyclic carbon atoms containing six-membered aromatic rings and other rings, e.g. cyclohexylphenylacetic acid
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C2601/00—Systems containing only non-condensed rings
    • C07C2601/06—Systems containing only non-condensed rings with a five-membered ring
    • C07C2601/08—Systems containing only non-condensed rings with a five-membered ring the ring being saturated

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
ES468578A 1977-04-05 1978-04-05 Un procedimiento para la preparacion de derivados del acido fenilacetico cicloalcano-sustituidos Expired ES468578A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
JP3890677A JPS584699B2 (ja) 1977-04-05 1977-04-05 置換フエニル酢酸誘導体及びその製法
JP3890777A JPS6034539B2 (ja) 1977-04-05 1977-04-05 オキシム置換フエニル酢酸誘導体及びその製法
JP6846877A JPS6034540B2 (ja) 1977-06-10 1977-06-10 オキシム置換フエニル酢酸誘導体の製造法

Publications (1)

Publication Number Publication Date
ES468578A1 true ES468578A1 (es) 1979-09-16

Family

ID=27289981

Family Applications (1)

Application Number Title Priority Date Filing Date
ES468578A Expired ES468578A1 (es) 1977-04-05 1978-04-05 Un procedimiento para la preparacion de derivados del acido fenilacetico cicloalcano-sustituidos

Country Status (11)

Country Link
US (1) US4161538A (sv)
BE (1) BE869097A (sv)
CA (1) CA1113113A (sv)
CH (1) CH633515A5 (sv)
DE (1) DE2814556A1 (sv)
DK (1) DK150472C (sv)
ES (1) ES468578A1 (sv)
FR (1) FR2395256A1 (sv)
GB (1) GB1580113A (sv)
NL (1) NL190519C (sv)
SE (1) SE437261B (sv)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DD141422A5 (de) * 1978-01-27 1980-04-30 Schering Ag Verfahren zur herstellung von phenylessigsaeure-derivaten
EP0007319B1 (de) * 1978-07-21 1981-09-16 Schering Aktiengesellschaft Neue Indan-1-carbonsäure-Derivate, Verfahren zu ihrer Herstellung, und diese Verbindungen enthaltende pharmazeutische Präparate
CH645539A5 (de) * 1980-06-09 1984-10-15 Sankyo Co Antiinflammatorische mittel fuer die aeusserliche anwendung.
US4423068A (en) * 1982-07-14 1983-12-27 Syntex (U.S.A.) Inc. (3.2.0) Bicycloheptanone oxime ethers with therapeutic properties
JPS59196839A (ja) * 1983-04-21 1984-11-08 Sankyo Co Ltd フエニル酢酸誘導体
JPS6038323A (ja) * 1983-08-10 1985-02-27 Sankyo Co Ltd 眼科用消炎剤
SE8400239D0 (sv) * 1984-01-19 1984-01-19 Pharmacia Ab Nya arylettiksyraderivat
JPS61268621A (ja) * 1985-05-21 1986-11-28 Sankyo Co Ltd シロツプ製剤
US4968718A (en) * 1988-01-25 1990-11-06 University Of Iowa Research Foundation Topically effective, nonsteroidal drug for use in external and internal eye inflammations
US5179124A (en) * 1988-01-25 1993-01-12 University Of Iowa Research Foundation Anti-inflammatory for use in external and internal eye inflammations
US5700947A (en) * 1993-10-06 1997-12-23 Nicox S.A. Nitric esters having anti-inflammatory and/or analgesic activity and process for their preparation
IT1282660B1 (it) * 1996-02-21 1998-03-31 Chemi Spa Processo per produrre l'acido (t) 2- 4-2-oxociclopentilmetil) fenilpropionico ed i suoi sali
IT1308633B1 (it) 1999-03-02 2002-01-09 Nicox Sa Nitrossiderivati.
KR100695334B1 (ko) * 2000-02-10 2007-03-15 니뽄 세키유 가가쿠 가부시키가이샤 2-치환 프로피온산의 제조방법
IT1318673B1 (it) * 2000-08-08 2003-08-27 Nicox Sa Farmaci per le disfunzioni sessuali.
IT1318674B1 (it) * 2000-08-08 2003-08-27 Nicox Sa Faramaci per l'incontinenza.
MY144587A (en) * 2001-06-21 2011-10-14 Kao Corp Polishing composition
ITMI20020773A1 (it) * 2002-04-11 2003-10-13 Nicox Sa Farmaci per il trattamento dell'artrite
TW200827343A (en) 2006-09-11 2008-07-01 Fuji Yakuhin Co Ltd Novel phenylacetic acid derivative
JP5390883B2 (ja) 2009-02-26 2014-01-15 国立大学法人 熊本大学 ロキソプロフェン誘導体及びそれを含有する医薬
WO2014167509A2 (en) * 2013-04-10 2014-10-16 Shasun Pharmaceuticals Limited Loxoprofen polymorphs and process for preparation of the same
EP2926810A1 (en) 2014-03-31 2015-10-07 Sanovel Ilac Sanayi ve Ticaret A.S. Oral liquid pharmaceutical formulations of loxoprofen
EP2926832A1 (en) 2014-03-31 2015-10-07 Sanovel Ilac Sanayi ve Ticaret A.S. Pharmaceutical formulations of loxoprofen for topical use
EP2939666A1 (en) 2014-04-29 2015-11-04 Sanovel Ilac Sanayi ve Ticaret A.S. Pharmaceutical formulations of loxoprofen
EP2959889A1 (en) 2014-06-25 2015-12-30 Sanovel Ilac Sanayi ve Ticaret A.S. Orally disintegrating formulations of loxoprofen
US20170151177A1 (en) 2014-06-30 2017-06-01 Sanovel Ilac Sanayi Ve Ticaret Anonim Sirketi Loxoprofen and gamma-aminobutiric acid receptor agonist combinations
EP3197434A1 (en) 2014-09-24 2017-08-02 Sanovel Ilac Sanayi ve Ticaret A.S. Loxoprofen and antispastic drug combinations
WO2016156354A1 (en) 2015-03-31 2016-10-06 Sanovel Ilac Sanayi Ve Ticaret A.S. Pharmaceutical composition comprising loxoprofen, glucosamine, chondroitin, hyaluronic acid for joint and cartilage disorders
CN109467506B (zh) * 2017-09-07 2021-12-07 江苏瑞科医药科技有限公司 一种取代苯乙酸衍生物的制备方法
CN108997119B (zh) * 2018-07-13 2020-10-20 湖北迅达药业股份有限公司 洛索洛芬钠合成工艺中缩合反应中间体的纯化方法
CN112851500B (zh) * 2021-02-10 2022-11-29 南京知和医药科技有限公司 S-洛索洛芬衍生物及其制备方法、药物组合物和用途

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB971700A (en) * 1961-02-02 1964-09-30 Boots Pure Drug Co Ltd Anti-Inflammatory Agents
US3894080A (en) * 1970-05-05 1975-07-08 Rorer Inc William H Phenylacetic acids
US3825587A (en) * 1970-05-05 1974-07-23 Rorer Inc William H Substituted phenylacetic acid compounds
US3864384A (en) * 1970-05-05 1975-02-04 Rorer Inc William H Substituted phenylacetic acid compounds
US4008269A (en) * 1970-05-05 1977-02-15 William H. Rorer, Inc. Phenylacetic acids
GB1364075A (en) * 1971-09-04 1974-08-21 Logeais Labor Jacques Phenylacetic acid derivatives process for their preparation and therapeutic compositions
FR2243680B2 (sv) * 1973-09-17 1977-01-28 Logeais Labor Jacques

Also Published As

Publication number Publication date
BE869097A (fr) 1979-01-18
CA1113113A (en) 1981-11-24
FR2395256B1 (sv) 1982-12-10
DE2814556C2 (sv) 1987-03-12
NL190519C (nl) 1994-04-05
DE2814556A1 (de) 1978-10-12
DK148478A (da) 1978-10-06
NL190519B (nl) 1993-11-01
FR2395256A1 (fr) 1979-01-19
GB1580113A (en) 1980-11-26
DK150472B (da) 1987-03-09
US4161538A (en) 1979-07-17
DK150472C (da) 1987-12-14
SE437261B (sv) 1985-02-18
CH633515A5 (de) 1982-12-15
NL7803644A (nl) 1978-10-09
SE7803848L (sv) 1978-10-06

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