ES430116A1 - Un procedimiento mejorado para la preparacion de cefalexinay sales no toxicas y farmaceuticamente aceptables de la mis-ma. - Google Patents

Un procedimiento mejorado para la preparacion de cefalexinay sales no toxicas y farmaceuticamente aceptables de la mis-ma.

Info

Publication number
ES430116A1
ES430116A1 ES430116A ES430116A ES430116A1 ES 430116 A1 ES430116 A1 ES 430116A1 ES 430116 A ES430116 A ES 430116A ES 430116 A ES430116 A ES 430116A ES 430116 A1 ES430116 A1 ES 430116A1
Authority
ES
Spain
Prior art keywords
acid
amino
alcoholysis
silyl
compound
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES430116A
Other languages
English (en)
Inventor
J Rubinfeld
R Lemiuex
R Raap
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Bristol Myers Co
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of ES430116A1 publication Critical patent/ES430116A1/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D501/00—Heterocyclic compounds containing 5-thia-1-azabicyclo [4.2.0] octane ring systems, i.e. compounds containing a ring system of the formula:, e.g. cephalosporins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulfur-containing hetero ring
    • C07D501/02—Preparation
    • C07D501/08—Preparation by forming the ring or condensed ring systems
    • C07D501/10—Preparation by forming the ring or condensed ring systems from compounds containing the penicillin ring system

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Catalysts (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
ES430116A 1971-05-11 1974-09-16 Un procedimiento mejorado para la preparacion de cefalexinay sales no toxicas y farmaceuticamente aceptables de la mis-ma. Expired ES430116A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US00143683A US3843637A (en) 1971-05-11 1971-05-11 Process for rearranging 6-acylamidopenicillanic acid-1-oxides to 7-acyla mido-3-methyl-ceph-3-em-4-carboxylic acids

Publications (1)

Publication Number Publication Date
ES430116A1 true ES430116A1 (es) 1976-10-16

Family

ID=22505135

Family Applications (3)

Application Number Title Priority Date Filing Date
ES402672A Expired ES402672A1 (es) 1971-05-11 1972-05-12 Un procedimiento para la transposicion de un sulfoxido de acido 6-acilamidopenicilanico a acido 7-acilamido-3-metilcef-3-em-4-carboxilico.
ES430117A Expired ES430117A1 (es) 1971-05-11 1974-09-16 Un procedimiento mejorado para la preparacion de hetacefa- lexina.
ES430116A Expired ES430116A1 (es) 1971-05-11 1974-09-16 Un procedimiento mejorado para la preparacion de cefalexinay sales no toxicas y farmaceuticamente aceptables de la mis-ma.

Family Applications Before (2)

Application Number Title Priority Date Filing Date
ES402672A Expired ES402672A1 (es) 1971-05-11 1972-05-12 Un procedimiento para la transposicion de un sulfoxido de acido 6-acilamidopenicilanico a acido 7-acilamido-3-metilcef-3-em-4-carboxilico.
ES430117A Expired ES430117A1 (es) 1971-05-11 1974-09-16 Un procedimiento mejorado para la preparacion de hetacefa- lexina.

Country Status (27)

Country Link
US (1) US3843637A (es)
JP (3) JPS565229B1 (es)
AR (3) AR194364A1 (es)
AT (1) AT325201B (es)
AU (1) AU461358B2 (es)
BE (1) BE783222A (es)
CA (1) CA986096A (es)
CH (1) CH578007A5 (es)
CS (3) CS190399B2 (es)
DD (1) DD99584A5 (es)
DE (1) DE2222953A1 (es)
DK (1) DK140845B (es)
ES (3) ES402672A1 (es)
FI (1) FI58925C (es)
FR (1) FR2143667B1 (es)
GB (1) GB1391838A (es)
HU (2) HU165177B (es)
IE (1) IE36353B1 (es)
IL (1) IL39382A (es)
NL (1) NL7206193A (es)
NO (3) NO146202C (es)
PH (1) PH13518A (es)
PL (3) PL94780B1 (es)
SE (3) SE411045B (es)
SU (2) SU626704A3 (es)
YU (3) YU122672A (es)
ZA (1) ZA723119B (es)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2143211B1 (es) * 1971-06-24 1975-10-31 Fujisawa Pharmaceutical Co
JPS536158B2 (es) * 1972-03-23 1978-03-04
US3960851A (en) * 1972-05-15 1976-06-01 Eli Lilly And Company Preparation of desacetoxy-cephalosporin sulfoxides from penicillin sulfoxides
GB1441587A (en) * 1972-07-14 1976-07-07 Glaxo Lab Ltd Cephalosporin compounds
GB1442785A (en) * 1972-12-09 1976-07-14 Nikken Chemicals Co Ltd Desacetoxy ceaphalosporanic acids
GB1465893A (en) * 1973-02-09 1977-03-02 Gist Brocades Nv I-carboxypropenyl-4-iminothio-azetidine-2-one derivatives methods for their preparation and use
US4010156A (en) * 1973-04-19 1977-03-01 American Home Products Corporation Process for the rearrangement of penicillins to cephalosporins and intermediate compounds thereof
JPS5084591A (es) * 1973-11-29 1975-07-08
US3953440A (en) * 1974-12-13 1976-04-27 Eli Lilly And Company Deacetoxycephalosporins via penicillin sulfoxide rearrangement
US4061862A (en) * 1975-10-06 1977-12-06 Bristol-Myers Company Derivatives of 7-(cyclized)phenylglycyl-3-triazolo-thio methyl cephalosporin
US4091213A (en) * 1975-12-12 1978-05-23 Bristol-Myers Company 7-Cyclizedamino-3-heterothiomethyl cephalosporin derivatives
US4182709A (en) * 1976-01-15 1980-01-08 Glaxo Group Limited Manufacture of semi-synthetic penicillin antibiotics
CN102470648B (zh) 2009-07-08 2015-07-08 利乐拉瓦尔集团及财务有限公司 无箔包装层压材料和其制造方法以及由其制成的包装容器

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2011376B2 (de) * 1969-03-11 1975-08-28 Glaxo Laboratories Ltd., Greenford, Middlesex (Grossbritannien) Verfahren zur Herstellung von 7beta-Acylamido-S-methylceph-S-em^-carbonsäureestern

Also Published As

Publication number Publication date
JPS55108875A (en) 1980-08-21
GB1391838A (en) 1975-04-23
AR194364A1 (es) 1973-07-13
NO146202C (no) 1982-08-18
YU174979A (en) 1983-01-21
PL94030B1 (es) 1977-07-30
SU626704A3 (ru) 1978-09-30
ES402672A1 (es) 1975-10-16
CS190367B2 (en) 1979-05-31
DE2222953A1 (de) 1973-03-01
CS190400B2 (en) 1979-05-31
NO146203C (no) 1982-08-18
IE36353L (en) 1972-11-11
IL39382A (en) 1975-07-28
AT325201B (de) 1975-10-10
SE414177B (sv) 1980-07-14
DK140845B (da) 1979-11-26
SE7414728L (es) 1974-11-22
BE783222A (fr) 1972-11-09
AR200720A1 (es) 1974-12-13
JPS565229B1 (es) 1981-02-04
SU662013A3 (ru) 1979-05-05
FI58925B (fi) 1981-01-30
NO146241B (no) 1982-05-18
PH13518A (en) 1980-06-03
HU166186B (es) 1975-02-28
US3843637A (en) 1974-10-22
NO146203B (no) 1982-05-10
HU165177B (es) 1974-07-27
FI58925C (fi) 1981-05-11
YU174879A (en) 1983-02-28
NL7206193A (es) 1972-11-14
PL94780B1 (pl) 1977-08-31
IE36353B1 (en) 1976-10-13
SE411045B (sv) 1979-11-26
ZA723119B (en) 1973-05-30
AR197310A1 (es) 1974-03-29
DK140845C (es) 1980-05-12
FR2143667B1 (es) 1977-01-28
PL85195B1 (es) 1976-04-30
CS190399B2 (en) 1979-05-31
AU4187672A (en) 1973-11-08
NO146241C (no) 1982-08-25
FR2143667A1 (es) 1973-02-09
JPS55108876A (en) 1980-08-21
IL39382A0 (en) 1972-07-26
DD99584A5 (es) 1973-08-12
YU122672A (en) 1982-02-28
AU461358B2 (en) 1975-05-22
ES430117A1 (es) 1976-10-16
NO146202B (no) 1982-05-10
SE7414727L (es) 1974-11-22
SE414176B (sv) 1980-07-14
JPS565758B2 (es) 1981-02-06
CA986096A (en) 1976-03-23
CH578007A5 (es) 1976-07-30
JPS565759B2 (es) 1981-02-06

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