ES2980417T3 - Composiciones que comprenden anticuerpos anti-CEACAM1 y anti-PD para la terapia del cáncer - Google Patents
Composiciones que comprenden anticuerpos anti-CEACAM1 y anti-PD para la terapia del cáncer Download PDFInfo
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- ES2980417T3 ES2980417T3 ES20151989T ES20151989T ES2980417T3 ES 2980417 T3 ES2980417 T3 ES 2980417T3 ES 20151989 T ES20151989 T ES 20151989T ES 20151989 T ES20151989 T ES 20151989T ES 2980417 T3 ES2980417 T3 ES 2980417T3
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| US10570204B2 (en) | 2013-09-26 | 2020-02-25 | The Medical College Of Wisconsin, Inc. | Methods for treating hematologic cancers |
| SG11201604738TA (en) | 2013-12-12 | 2016-07-28 | Shanghai Hengrui Pharm Co Ltd | Pd-1 antibody, antigen-binding fragment thereof, and medical application thereof |
| KR102452349B1 (ko) * | 2014-04-27 | 2022-10-11 | 페임웨이브 리미티드 | Ceacam1에 대한 인간화 항체 |
| US11427647B2 (en) | 2014-04-27 | 2022-08-30 | Famewave Ltd. | Polynucleotides encoding humanized antibodies against CEACAM1 |
| BR112017004826A2 (pt) | 2014-09-13 | 2017-12-12 | Novartis Ag | terapias de combinação de inibidores de alk |
| CA2978942A1 (en) | 2015-03-13 | 2016-09-22 | Cytomx Therapeutics, Inc. | Anti-pdl1 antibodies, activatable anti-pdl1 antibodies, and methods of use thereof |
| JP7014706B2 (ja) | 2015-07-13 | 2022-02-01 | サイトメックス セラピューティクス インコーポレイテッド | 抗ｐｄ－１抗体、活性化可能抗ｐｄ－１抗体、およびその使用方法 |
| CN114605548A (zh) | 2015-09-01 | 2022-06-10 | 艾吉纳斯公司 | 抗-pd-1抗体及其使用方法 |
| CN106699889A (zh) * | 2015-11-18 | 2017-05-24 | 礼进生物医药科技（上海）有限公司 | 抗pd-1抗体及其治疗用途 |
| CN107345968A (zh) * | 2016-05-05 | 2017-11-14 | 中国医学科学院基础医学研究所 | Cecam1蛋白作为血清标记物在诊断肝脏疾病中的用途 |
| CN107345969A (zh) * | 2016-05-05 | 2017-11-14 | 中国医学科学院基础医学研究所 | 包含afp、gp73和ceacam1的血清标记物在诊断肝脏疾病中的用途 |
| MX2019005491A (es) | 2016-11-14 | 2019-08-12 | Dinona | Anticuerpo que enlaza especificamente a cd66c y uso del mismo. |
| KR102603681B1 (ko) | 2016-12-07 | 2023-11-17 | 아게누스 인코포레이티드 | 항체 및 이의 사용방법 |
| CN106957823A (zh) * | 2016-12-28 | 2017-07-18 | 无锡傲锐东源生物科技有限公司 | 抗pd‑l2蛋白单克隆抗体及其用途 |
| KR102019913B1 (ko) * | 2017-03-24 | 2019-09-09 | 재단법인 목암생명과학연구소 | 항-ceacam1 항체 및 이의 용도 |
| KR20200016899A (ko) | 2017-06-01 | 2020-02-17 | 싸이톰스 테라퓨틱스, 인크. | 활성화가능 항-pdl1 항체, 및 이의 이용 방법 |
| US12173066B2 (en) * | 2018-12-07 | 2024-12-24 | The Brigham And Women's Hospital, Inc. | Humanized and affinity-matured anti-CEACAM1 antibodies |
| EP3898694A4 (en) * | 2018-12-20 | 2023-02-15 | Albert Einstein College of Medicine | ANTAGONIST ANTIBODIES TO HUMAN IMMUNOBAL SCORE CEACAM1 (CD66A) AND FORMULATIONS, KITS AND METHODS OF USE THEREOF |
| KR102166982B1 (ko) * | 2019-01-24 | 2020-10-16 | 가톨릭대학교 산학협력단 | 간암에서 CEACAM1 및 EpCAM의 상관관계 및 이를 이용한 간암 치료효과에 대한 정보를 제공하는 방법 |
| CN114949201A (zh) * | 2019-03-12 | 2022-08-30 | 哈佛大学校长及研究员协会 | 治疗癌症的方法和组合物 |
| WO2021024020A1 (en) | 2019-08-06 | 2021-02-11 | Astellas Pharma Inc. | Combination therapy involving antibodies against claudin 18.2 and immune checkpoint inhibitors for treatment of cancer |
| AU2021306613A1 (en) | 2020-07-07 | 2023-02-02 | BioNTech SE | Therapeutic RNA for HPV-positive cancer |
| WO2022116079A1 (zh) * | 2020-12-03 | 2022-06-09 | 上海吉倍生物技术有限公司 | 一种抗ceacam5的人源化抗体及其制备方法和用途 |
| WO2022135666A1 (en) | 2020-12-21 | 2022-06-30 | BioNTech SE | Treatment schedule for cytokine proteins |
| TW202245808A (zh) | 2020-12-21 | 2022-12-01 | 德商拜恩迪克公司 | 用於治療癌症之治療性ｒｎａ |
| WO2022135667A1 (en) | 2020-12-21 | 2022-06-30 | BioNTech SE | Therapeutic rna for treating cancer |
| CA3225254A1 (en) | 2021-07-13 | 2023-01-19 | BioNTech SE | Multispecific binding agents against cd40 and cd137 in combination therapy for cancer |
| TW202333802A (zh) | 2021-10-11 | 2023-09-01 | 德商拜恩迪克公司 | 用於肺癌之治療性rna(二) |
| KR20250139898A (ko) * | 2022-11-10 | 2025-09-23 | 페임웨이브 리미티드 | 호중구 세포외 트랩 (net) 매개 활성 억제를 위한 항암배아항원 관련 세포 부착 분자 1 (ceacam1) 항체 |
| WO2024120084A1 (zh) * | 2022-12-07 | 2024-06-13 | 宜明昂科生物医药技术（上海）股份有限公司 | 使用cd24抗体和pd-1-pd-l1通路阻断抗体的癌症联合疗法 |
| KR20250120305A (ko) | 2022-12-14 | 2025-08-08 | 아스텔라스 파마 유럽 비.브이. | Cldn18.2 및 cd3에 결합하는 2중 특이성 결합제와 면역 체크포인트 저해제를 수반한 조합 요법 |
| KR20240113400A (ko) * | 2023-01-11 | 2024-07-22 | 한국과학기술원 | 종양 내 Treg의 바이오마커를 포함하는 진단용 조성물 및 약학 조성물 |
| WO2024213096A1 (en) * | 2023-04-13 | 2024-10-17 | Suzhou Neologics Bioscience Co., Ltd. | Ceacam1-targeting antibodies and uses thereof |
| WO2025120867A1 (en) | 2023-12-08 | 2025-06-12 | Astellas Pharma Inc. | Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and anti-vegfr2 antibodies |
| WO2025120866A1 (en) | 2023-12-08 | 2025-06-12 | Astellas Pharma Inc. | Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2 |
| WO2025121445A1 (en) | 2023-12-08 | 2025-06-12 | Astellas Pharma Inc. | Combination therapy involving bispecific binding agents binding to cldn18.2 and cd3 and agents stabilizing or increasing expression of cldn18.2 |
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| HK1225998A1 (zh) | 2017-09-22 |
| MX2016006726A (es) | 2016-12-16 |
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| KR20160108310A (ko) | 2016-09-19 |
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| KR102362803B1 (ko) | 2022-02-14 |
| EP3074035A4 (en) | 2017-06-21 |
| BR112016010557A2 (pt) | 2017-12-05 |
| EP3074035A1 (en) | 2016-10-05 |
| CA2930218C (en) | 2020-11-17 |
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| WO2015075725A1 (en) | 2015-05-28 |
| AU2014351308B2 (en) | 2020-03-05 |
| EP3763387A1 (en) | 2021-01-13 |
| PL3074035T3 (pl) | 2021-03-08 |
| US10081679B2 (en) | 2018-09-25 |
| MX375221B (es) | 2025-03-06 |
| CN105744955A (zh) | 2016-07-06 |
| RU2016124540A (ru) | 2017-12-29 |
| JP2020055853A (ja) | 2020-04-09 |
| CN105744955B (zh) | 2020-03-20 |
| AU2014351308A1 (en) | 2016-05-05 |
| CA2930218A1 (en) | 2015-05-28 |
| US20170166637A1 (en) | 2017-06-15 |
| RU2697522C1 (ru) | 2019-08-15 |
| EP3074035B1 (en) | 2020-05-13 |
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