ES2970324T3 - Adormidera con alto contenido de tebaína y métodos para producirla - Google Patents
Adormidera con alto contenido de tebaína y métodos para producirla Download PDFInfo
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- ES2970324T3 ES2970324T3 ES17838267T ES17838267T ES2970324T3 ES 2970324 T3 ES2970324 T3 ES 2970324T3 ES 17838267 T ES17838267 T ES 17838267T ES 17838267 T ES17838267 T ES 17838267T ES 2970324 T3 ES2970324 T3 ES 2970324T3
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- C12Y—ENZYMES
- C12Y114/00—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14)
- C12Y114/11—Oxidoreductases acting on paired donors, with incorporation or reduction of molecular oxygen (1.14) with 2-oxoglutarate as one donor, and incorporation of one atom each of oxygen into both donors (1.14.11)
- C12Y114/11032—Codeine 3-O-demethylase (1.14.11.32)
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Applications Claiming Priority (3)
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|---|---|---|---|
| US201662374682P | 2016-08-12 | 2016-08-12 | |
| CA2941315A CA2941315C (en) | 2016-08-12 | 2016-09-07 | High thebaine poppy and methods of producing the same |
| PCT/CA2017/050951 WO2018027324A1 (en) | 2016-08-12 | 2017-08-11 | High thebaine poppy and methods of producing the same |
Publications (1)
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| ES2970324T3 true ES2970324T3 (es) | 2024-05-28 |
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| ES17838267T Active ES2970324T3 (es) | 2016-08-12 | 2017-08-11 | Adormidera con alto contenido de tebaína y métodos para producirla |
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| Country | Link |
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| US (2) | US10808258B2 (https=) |
| EP (1) | EP3334826B1 (https=) |
| JP (2) | JP6906812B2 (https=) |
| CN (1) | CN110088284A (https=) |
| AU (3) | AU2017310339B2 (https=) |
| CA (1) | CA2941315C (https=) |
| DK (1) | DK3334826T5 (https=) |
| ES (1) | ES2970324T3 (https=) |
| HU (1) | HUE065349T2 (https=) |
| PT (1) | PT3334826T (https=) |
| WO (1) | WO2018027324A1 (https=) |
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| DK3553177T3 (da) | 2013-03-15 | 2021-02-15 | Univ Leland Stanford Junior | Benzylisoquinolinalkaloider (bia) som producerer mikrober, og fremgangsmåder til fremstilling og anvendelse deraf |
| CN112410379B (zh) | 2013-11-04 | 2024-12-31 | 小利兰·斯坦福大学托管委员会 | 产生苄基异喹啉生物碱(bia)前体的微生物以及制备和使用所述前体的方法 |
| EP3292203A4 (en) | 2015-05-04 | 2019-10-09 | The Board of Trustees of the Leland Stanford Junior University | BENZYL ISOCHINOLIN ALKALOID (BIA) Precursor Producing Microbicides and Method for the Preparation and Use Thereof |
| JP7266966B2 (ja) | 2015-05-08 | 2023-05-01 | ザ ボード オブ トラスティーズ オブ ザ レランド スタンフォード ジュニア ユニバーシティー | エピメラーゼ及びベンジルイソキノリンアルカロイドを産生する方法 |
| WO2018075670A1 (en) | 2016-10-18 | 2018-04-26 | Antheia, Inc. | Methods of producing nor-opioid and nal-opioid benzylisoquinoline alkaloids |
| AU2018203033B2 (en) * | 2017-05-02 | 2021-07-01 | Sun Pharmaceutical Industries Australia Pty Limited | Modified plant |
| WO2019028390A1 (en) | 2017-08-03 | 2019-02-07 | Antheia, Inc. | ALKALOID BENZYLISOQUINOLEIN GENETICALLY MODIFIED EPIMERASES AND METHODS FOR PRODUCING BENZYLISOQUINOLINE ALKALOIDS |
| EP3758728A4 (en) * | 2018-03-02 | 2021-12-22 | Tasmanian Alkaloids Pty. Ltd. | PAPAVER SOMNIFERUM PLANT WITH AN MODIFIED ALKALOID PROFILE |
| CN120399912A (zh) | 2019-03-08 | 2025-08-01 | 小利兰·斯坦福大学托管委员会 | 产生莨菪烷生物碱(ta)的非植物宿主细胞及其制备和使用方法 |
| JP7555091B2 (ja) * | 2020-02-29 | 2024-09-24 | 国立大学法人千葉大学 | 代謝物センサ及び酵素活性のスクリーニング方法 |
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| US6067749A (en) * | 1996-07-11 | 2000-05-30 | Tasmanian Alkaloids Pty. Ltd. | Papaver somniferum strain with high concentration of thebaine and oripavine |
| GB9710809D0 (en) | 1997-05-23 | 1997-07-23 | Medical Res Council | Nucleic acid binding proteins |
| CA2317508A1 (en) | 1998-01-08 | 1999-07-15 | Commonwealth Scientific And Industrial Research Organisation | Methods for plant transformation and regeneration |
| US6453242B1 (en) | 1999-01-12 | 2002-09-17 | Sangamo Biosciences, Inc. | Selection of sites for targeting by zinc finger proteins and methods of designing zinc finger proteins to bind to preselected sites |
| US6730838B1 (en) | 1999-02-12 | 2004-05-04 | Council Of Scientific And Industrial Research | Opiumless and alkaloid-free non-narcotic opium poppy (Papaver somniferum) variety “Sujata” |
| AUPP946399A0 (en) | 1999-03-26 | 1999-04-22 | Johnson & Johnson Research Pty. Limited | Codeinone reductase from alkaloid poppy |
| EP1270727A1 (en) | 2001-06-11 | 2003-01-02 | Institut für Pflanzenbiochemie | Salutaridinol 7-O-acetyltransferase and derivatives thereof |
| CH695417A5 (de) * | 2001-11-15 | 2006-05-15 | Ddr Wassyl Nowicky Dipl Ing | Verfahren zur Umsetzung von Alkaloiden. |
| US6790959B1 (en) | 2003-06-05 | 2004-09-14 | Halsey Drug Company, Inc. | Process for manufacturing thebaine |
| US6864370B1 (en) | 2003-06-05 | 2005-03-08 | Zhaiwei Lin | Process for manufacturing oxycodone |
| EP1512748A1 (en) | 2003-09-03 | 2005-03-09 | Johnson & Johnson Research Pty Limited | O-methyltransferases of tetrahydrobenzylisoquinoline alkaloid biosynthesis in papaver somniferum |
| EP1632565A1 (en) | 2004-08-12 | 2006-03-08 | Johnson & Johnson Research Pty Limited | Modulation of alkaloid biosynthesis in plants and plants having altered alkaloid biosynthesis |
| DE102005005449A1 (de) * | 2005-02-04 | 2006-08-10 | Grünenthal GmbH | Verfahren zur Herstellung einer gegen Missbrauch gesicherten Darreichungsform |
| AU2006216715A1 (en) | 2005-02-22 | 2006-08-31 | Ceres Inc. | Modulating plant alkaloids |
| WO2006115575A1 (en) | 2005-04-20 | 2006-11-02 | Ceres Inc. | Regulatory regions from papaveraceae |
| US9131649B2 (en) * | 2008-03-07 | 2015-09-15 | Tasmanian Alkaloids Pty. Ltd | Papaver somniferum strain with high concentration of thebaine |
| US8541647B2 (en) | 2008-05-29 | 2013-09-24 | Tasmania Alkaloids Pty, Ltd. | Papaver somniferum with high concentration of codeine |
| US8586526B2 (en) | 2010-05-17 | 2013-11-19 | Sangamo Biosciences, Inc. | DNA-binding proteins and uses thereof |
| WO2011058446A2 (en) * | 2009-11-12 | 2011-05-19 | Uti Limited Partnership | Thebaine 6-o-demethylase and codeine o-demethylase from papaver somniferum |
| CA2872079A1 (en) * | 2012-04-30 | 2013-11-07 | Tpi Enterprises Ltd | Papaver bracteatum with modified alkaloid content |
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2016
- 2016-09-07 CA CA2941315A patent/CA2941315C/en active Active
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2017
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- 2017-08-11 DK DK17838267.7T patent/DK3334826T5/da active
- 2017-08-11 CN CN201780063464.9A patent/CN110088284A/zh active Pending
- 2017-08-11 US US15/762,090 patent/US10808258B2/en active Active
- 2017-08-11 HU HUE17838267A patent/HUE065349T2/hu unknown
- 2017-08-11 AU AU2017310339A patent/AU2017310339B2/en active Active
- 2017-08-11 ES ES17838267T patent/ES2970324T3/es active Active
- 2017-08-11 WO PCT/CA2017/050951 patent/WO2018027324A1/en not_active Ceased
- 2017-08-11 PT PT178382677T patent/PT3334826T/pt unknown
- 2017-08-11 JP JP2019521398A patent/JP6906812B2/ja active Active
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2019
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2021
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| DK3334826T5 (da) | 2024-10-07 |
| PT3334826T (pt) | 2024-02-07 |
| CN110088284A (zh) | 2019-08-02 |
| HUE065349T2 (hu) | 2024-05-28 |
| AU2017310339A1 (en) | 2018-04-12 |
| JP2021000097A (ja) | 2021-01-07 |
| US20190169625A1 (en) | 2019-06-06 |
| CA2941315A1 (en) | 2016-11-08 |
| EP3334826A1 (en) | 2018-06-20 |
| AU2019201771A1 (en) | 2019-04-04 |
| US10808258B2 (en) | 2020-10-20 |
| JP6906812B2 (ja) | 2021-07-21 |
| DK3334826T3 (da) | 2024-01-15 |
| JP2019528084A (ja) | 2019-10-10 |
| US20210246460A1 (en) | 2021-08-12 |
| WO2018027324A9 (en) | 2019-07-18 |
| CA2941315C (en) | 2018-03-06 |
| EP3334826A4 (en) | 2018-08-08 |
| EP3334826B1 (en) | 2023-10-11 |
| WO2018027324A1 (en) | 2018-02-15 |
| AU2017310339B2 (en) | 2019-01-17 |
| AU2021232757A1 (en) | 2021-10-21 |
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