ES2934138T3 - Uso de un polipéptido para efectuar la señalización inmunitaria y/o afectar la función de la barrera intestinal y/o modular el estado metabólico - Google Patents

Uso de un polipéptido para efectuar la señalización inmunitaria y/o afectar la función de la barrera intestinal y/o modular el estado metabólico Download PDF

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Publication number
ES2934138T3
ES2934138T3 ES16724321T ES16724321T ES2934138T3 ES 2934138 T3 ES2934138 T3 ES 2934138T3 ES 16724321 T ES16724321 T ES 16724321T ES 16724321 T ES16724321 T ES 16724321T ES 2934138 T3 ES2934138 T3 ES 2934138T3
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Prior art keywords
polypeptide
acid sequence
amino acid
seq
taught
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ES16724321T
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English (en)
Spanish (es)
Inventor
Clara Belzer
Vos Willem Meindert De
Patrice Daniel Cani
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Universite Catholique de Louvain UCL
Wageningen Universiteit
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Universite Catholique de Louvain UCL
Wageningen Universiteit
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • A61K38/16Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/06Antihyperlipidemics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00Drugs for disorders of the metabolism
    • A61P3/08Drugs for disorders of the metabolism for glucose homeostasis
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00Microorganisms, e.g. protozoa; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20Bacteria; Culture media therefor
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
  • Biochemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Emergency Medicine (AREA)
  • Endocrinology (AREA)
  • Microbiology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ES16724321T 2015-05-06 2016-05-04 Uso de un polipéptido para efectuar la señalización inmunitaria y/o afectar la función de la barrera intestinal y/o modular el estado metabólico Active ES2934138T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP15166598 2015-05-06
PCT/EP2016/060033 WO2016177797A1 (en) 2015-05-06 2016-05-04 Use of a polypeptide for effecting immune signalling and/or affecting intestinal barrier function and/or modulating metabolic status

Publications (1)

Publication Number Publication Date
ES2934138T3 true ES2934138T3 (es) 2023-02-17

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ES16724321T Active ES2934138T3 (es) 2015-05-06 2016-05-04 Uso de un polipéptido para efectuar la señalización inmunitaria y/o afectar la función de la barrera intestinal y/o modular el estado metabólico

Country Status (14)

Country Link
US (2) US10738089B2 (enExample)
EP (1) EP3292135B1 (enExample)
JP (1) JP6894382B2 (enExample)
KR (1) KR102736980B1 (enExample)
CN (1) CN107980043B (enExample)
AU (2) AU2016257315A1 (enExample)
DK (1) DK3292135T3 (enExample)
EA (1) EA201700507A1 (enExample)
ES (1) ES2934138T3 (enExample)
HK (1) HK1252412A1 (enExample)
IL (1) IL255405B (enExample)
MX (1) MX390092B (enExample)
PL (1) PL3292135T3 (enExample)
WO (1) WO2016177797A1 (enExample)

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EP3823651A4 (en) 2018-07-19 2022-04-27 Pendulum Therapeutics, Inc. METHODS AND COMPOSITIONS FOR MICROBIAL TRANSPLANTATION
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KR102197180B1 (ko) 2018-10-11 2020-12-31 주식회사 고바이오랩 아커만시아 뮤시니필라 균주 및 이를 포함하는 식욕 억제 및 대사성 질환 예방, 개선, 완화 및 치료용 조성물
CN110079474B (zh) * 2019-04-12 2022-11-25 沈阳药科大学 一种高密度培养艾克曼嗜黏蛋白菌的方法
KR102263030B1 (ko) * 2019-05-07 2021-06-10 한국생명공학연구원 염증성 장질환의 예방 또는 치료용 펩타이드
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EP4079837A4 (en) * 2019-09-25 2024-06-05 HealthBiome, Inc. OBLIGATE ANAEROBIC HUMAN INTESTINAL MICROBES FOR CANCER TREATMENT AND ITS USE
KR102397916B1 (ko) * 2019-10-01 2022-05-17 (주)헬스바이옴 건강한 임산부 모유 유래 혐기성 인체 균주 및 이를 이용한 대사성 질환의 예방 또는 치료방법
CN110950937B (zh) * 2019-11-25 2021-05-04 安徽大学 一种改造的艾克曼菌Amuc_1100蛋白及其制备方法和应用
CN115315433A (zh) * 2020-01-10 2022-11-08 黄志宏 Tlr2交互作用的胜肽以及包括其的组合物
KR102671044B1 (ko) * 2020-03-25 2024-05-31 한국생명공학연구원 아커만시아 뮤시니필라 유래의 tars 또는 이의 단편 및 이의 용도
US20210322492A1 (en) * 2020-04-16 2021-10-21 Amucin Oy Ltd Probiotic strains and uses thereof
CN111690044B (zh) * 2020-05-06 2022-03-01 中南大学湘雅二医院 Amuc1100蛋白的用途
AU2021299904A1 (en) 2020-07-01 2023-01-19 Advanced Microbiome Interventions B.V. Amuc-1100 polypeptide variants for effecting immune signalling and/or affecting intestinal barrier function and/or modulating metabolic status
WO2022098051A1 (ko) * 2020-11-05 2022-05-12 한국생명공학연구원 항염 및 조직 재생작용을 갖는 신규 펩타이드
CN113413466B (zh) * 2020-12-15 2022-08-19 和度生物医药(上海)有限公司 用于治疗癌症的amuc_1100和免疫检查点调节剂的组合疗法
CN115364198A (zh) * 2022-08-23 2022-11-22 广州康泽医疗科技有限公司 膜蛋白Amuc_1100在促进前脂肪细胞脂解和棕色化中的应用
CN116059254B (zh) * 2023-02-27 2025-04-18 广州知易生物科技有限公司 嗜黏蛋白阿克曼氏菌在制备用于改善和治疗多发性硬化症药物中的应用
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CN117304264B (zh) * 2023-11-27 2024-02-06 中国科学院烟台海岸带研究所 一种具有肠屏障保护功能的五肽rp5及其应用
CN118063567B (zh) * 2024-03-03 2025-11-21 吉林大学 一种用于炎性肠病治疗的重组蛋白的制备与应用
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Also Published As

Publication number Publication date
MX390092B (es) 2025-03-11
CN107980043A (zh) 2018-05-01
KR20180011130A (ko) 2018-01-31
EA201700507A1 (ru) 2018-05-31
AU2020267210A1 (en) 2020-12-17
IL255405A0 (en) 2017-12-31
HK1252412A1 (zh) 2019-05-24
NZ737765A (en) 2024-08-30
AU2016257315A1 (en) 2017-11-23
US20180265554A1 (en) 2018-09-20
WO2016177797A1 (en) 2016-11-10
US10738089B2 (en) 2020-08-11
DK3292135T3 (da) 2022-10-31
MX2017014111A (es) 2018-02-26
AU2020267210B2 (en) 2023-10-12
PL3292135T3 (pl) 2023-01-02
KR102736980B1 (ko) 2024-12-02
JP2018515502A (ja) 2018-06-14
EP3292135B1 (en) 2022-09-21
JP6894382B2 (ja) 2021-06-30
EP3292135A1 (en) 2018-03-14
BR112017023751A2 (pt) 2018-07-31
CN107980043B (zh) 2021-09-24
CA2984985A1 (en) 2016-11-10
IL255405B (en) 2022-01-01
US11466057B2 (en) 2022-10-11
US20210147489A1 (en) 2021-05-20

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