JP6894382B2 - 免疫シグナル伝達をもたらし、かつ/または腸管バリア機能に影響を与え、かつ/または代謝状態を調節するためのポリペプチドの使用 - Google Patents

免疫シグナル伝達をもたらし、かつ/または腸管バリア機能に影響を与え、かつ/または代謝状態を調節するためのポリペプチドの使用 Download PDF

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JP6894382B2
JP6894382B2 JP2017557983A JP2017557983A JP6894382B2 JP 6894382 B2 JP6894382 B2 JP 6894382B2 JP 2017557983 A JP2017557983 A JP 2017557983A JP 2017557983 A JP2017557983 A JP 2017557983A JP 6894382 B2 JP6894382 B2 JP 6894382B2
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acid sequence
amino acid
seq
polypeptide
nucleic acid
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ベルザー,クララ
ヴォス,ウィレム マインダート デ
ヴォス,ウィレム マインダート デ
ダニエル カニ,パトリス
ダニエル カニ,パトリス
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ヴァーヘニンゲン ユニバーシテイト
ヴァーヘニンゲン ユニバーシテイト
ウニベルシテ カソリーク デ ルーベン
ウニベルシテ カソリーク デ ルーベン
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    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • A61K38/16—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • A61K38/164—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/06—Antihyperlipidemics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A61P3/08—Drugs for disorders of the metabolism for glucose homeostasis
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N1/00—Microorganisms; Compositions thereof; Processes of propagating, maintaining or preserving microorganisms or compositions thereof; Processes of preparing or isolating a composition containing a microorganism; Culture media therefor
    • C12N1/20—Bacteria; Culture media therefor
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

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  • Health & Medical Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
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  • Genetics & Genomics (AREA)
  • Diabetes (AREA)
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  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Obesity (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Hematology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biotechnology (AREA)
  • Wood Science & Technology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Emergency Medicine (AREA)
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  • Tropical Medicine & Parasitology (AREA)
  • Biomedical Technology (AREA)
  • General Engineering & Computer Science (AREA)
  • Microbiology (AREA)
  • Virology (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
JP2017557983A 2015-05-06 2016-05-04 免疫シグナル伝達をもたらし、かつ/または腸管バリア機能に影響を与え、かつ/または代謝状態を調節するためのポリペプチドの使用 Active JP6894382B2 (ja)

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EP15166598 2015-05-06
EP15166598.1 2015-05-06
PCT/EP2016/060033 WO2016177797A1 (en) 2015-05-06 2016-05-04 Use of a polypeptide for effecting immune signalling and/or affecting intestinal barrier function and/or modulating metabolic status

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US20210322492A1 (en) * 2020-04-16 2021-10-21 Amucin Oy Ltd Probiotic strains and uses thereof
CN111690044B (zh) * 2020-05-06 2022-03-01 中南大学湘雅二医院 Amuc1100蛋白的用途
WO2022002660A1 (en) 2020-07-01 2022-01-06 Wageningen Universiteit Amuc-1100 polypeptide variants for effecting immune signalling and/or affecting intestinal barrier function and/or modulating metabolic status
WO2022098051A1 (ko) * 2020-11-05 2022-05-12 한국생명공학연구원 항염 및 조직 재생작용을 갖는 신규 펩타이드
CN113413466B (zh) * 2020-12-15 2022-08-19 和度生物医药(上海)有限公司 用于治疗癌症的amuc_1100和免疫检查点调节剂的组合疗法
CN115364198A (zh) * 2022-08-23 2022-11-22 广州康泽医疗科技有限公司 膜蛋白Amuc_1100在促进前脂肪细胞脂解和棕色化中的应用
CN116059254B (zh) * 2023-02-27 2025-04-18 广州知易生物科技有限公司 嗜黏蛋白阿克曼氏菌在制备用于改善和治疗多发性硬化症药物中的应用
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PL3292135T3 (pl) 2023-01-02
CN107980043A (zh) 2018-05-01
WO2016177797A1 (en) 2016-11-10
ES2934138T3 (es) 2023-02-17
IL255405B (en) 2022-01-01
DK3292135T3 (da) 2022-10-31
US20210147489A1 (en) 2021-05-20
EA201700507A1 (ru) 2018-05-31
CN107980043B (zh) 2021-09-24
HK1252412A1 (zh) 2019-05-24
US11466057B2 (en) 2022-10-11
EP3292135A1 (en) 2018-03-14
US10738089B2 (en) 2020-08-11
KR102736980B1 (ko) 2024-12-02
AU2016257315A1 (en) 2017-11-23
AU2020267210A1 (en) 2020-12-17
MX390092B (es) 2025-03-11
KR20180011130A (ko) 2018-01-31
IL255405A0 (en) 2017-12-31
JP2018515502A (ja) 2018-06-14
CA2984985A1 (en) 2016-11-10
AU2020267210B2 (en) 2023-10-12
NZ737765A (en) 2024-08-30
MX2017014111A (es) 2018-02-26
EP3292135B1 (en) 2022-09-21
BR112017023751A2 (pt) 2018-07-31
US20180265554A1 (en) 2018-09-20

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