ES2887201T3 - Variantes de empalme asociadas con mutantes neomórficos de SF3B1 - Google Patents

Variantes de empalme asociadas con mutantes neomórficos de SF3B1 Download PDF

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ES2887201T3
ES2887201T3 ES16766420T ES16766420T ES2887201T3 ES 2887201 T3 ES2887201 T3 ES 2887201T3 ES 16766420 T ES16766420 T ES 16766420T ES 16766420 T ES16766420 T ES 16766420T ES 2887201 T3 ES2887201 T3 ES 2887201T3
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sf3b1
seq
cell
cancer
neomorphic
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Spanish (es)
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Lihua Yu
Kian Lim
Jacob Feala
Silvia Buonamici
Yoshiharu Mizui
Peter Smith
Ping Zhu
Eunice Park
Michael Seiler
Marco Fekkes
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Eisai R&D Management Co Ltd
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    • A61K31/33Heterocyclic compounds
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    • A61K31/33Heterocyclic compounds
    • A61K31/395Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
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ES16766420T 2015-09-01 2016-08-30 Variantes de empalme asociadas con mutantes neomórficos de SF3B1 Active ES2887201T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201562212876P 2015-09-01 2015-09-01
PCT/US2016/049490 WO2017040526A2 (en) 2015-09-01 2016-08-30 Splice variants associated with neomorphic sf3b1 mutants

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ES2887201T3 true ES2887201T3 (es) 2021-12-22

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US (2) US10889866B2 (cg-RX-API-DMAC7.html)
EP (2) EP3344780B1 (cg-RX-API-DMAC7.html)
JP (2) JP6876680B2 (cg-RX-API-DMAC7.html)
ES (1) ES2887201T3 (cg-RX-API-DMAC7.html)
WO (1) WO2017040526A2 (cg-RX-API-DMAC7.html)

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WO2017040526A2 (en) 2015-09-01 2017-03-09 Eisai R&D Management Co., Ltd. Splice variants associated with neomorphic sf3b1 mutants
US20200190593A1 (en) * 2017-03-15 2020-06-18 Eisai R&D Management Co., Ltd. Spliceosome mutations and uses thereof
WO2019027987A2 (en) * 2017-07-31 2019-02-07 The Johns Hopkins University COMPOSITIONS AND METHODS FOR TARGETING MASAS TO TREAT CANCERS WITH SPLICE COMPLEX MUTATIONS
KR20210006907A (ko) * 2018-04-09 2021-01-19 에자이 알앤드디 매니지먼트 가부시키가이샤 플라디에놀리드 화합물 및 그의 용도
CN112367996B (zh) 2018-06-01 2024-05-24 卫材R&D管理有限公司 使用剪接调节剂的方法
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US20220073971A1 (en) * 2019-02-08 2022-03-10 Zenick Corporation Method for analyzing mrna precursor, information processing apparatus, and computer program
JP6931860B2 (ja) * 2019-02-08 2021-09-08 株式会社Zenick mRNA前駆体の解析方法、情報処理装置、コンピュータプログラム
WO2020264177A1 (en) * 2019-06-26 2020-12-30 Fred Hutchinson Cancer Research Center Methods and compositions comprising brd9 activating therapies for treating cancers and related disorders
CN111518805A (zh) * 2020-04-30 2020-08-11 北京航空航天大学 一种可用于抑制肿瘤增殖的非编码基因及其应用
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CN116507334A (zh) * 2020-11-04 2023-07-28 卫材R&D管理有限公司 骨髓增生异常综合征(mds)的生物标记物及其使用方法
KR20230104204A (ko) 2020-11-04 2023-07-07 에자이 알앤드디 매니지먼트 가부시키가이샤 골수이형성 증후군(mds)에 대한 바이오마커 및 이를 사용하는 방법
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EP3910073A1 (en) 2021-11-17
US10889866B2 (en) 2021-01-12
US20180318312A1 (en) 2018-11-08
EP3344780B1 (en) 2021-06-23
JP7256840B2 (ja) 2023-04-12
EP3344780A2 (en) 2018-07-11
US11761045B2 (en) 2023-09-19
JP6876680B2 (ja) 2021-05-26
WO2017040526A2 (en) 2017-03-09
JP2018525994A (ja) 2018-09-13
JP2021106615A (ja) 2021-07-29
US20210130909A1 (en) 2021-05-06
WO2017040526A3 (en) 2017-04-20
EP3910073B1 (en) 2024-03-06

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