ES2885423T3 - Procedimientos para la expansión o el empobrecimiento de células T reguladoras - Google Patents

Procedimientos para la expansión o el empobrecimiento de células T reguladoras Download PDF

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ES2885423T3
ES2885423T3 ES14748807T ES14748807T ES2885423T3 ES 2885423 T3 ES2885423 T3 ES 2885423T3 ES 14748807 T ES14748807 T ES 14748807T ES 14748807 T ES14748807 T ES 14748807T ES 2885423 T3 ES2885423 T3 ES 2885423T3
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cancer
cells
virus
tnfr2
antibody
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Denise Faustman
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General Hospital Corp
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General Hospital Corp
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    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/14—Blood; Artificial blood
    • A61K35/17—Lymphocytes; B-cells; T-cells; Natural killer cells; Interferon-activated or cytokine-activated lymphocytes
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    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2878—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • C—CHEMISTRY; METALLURGY
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    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
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    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
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    • C12N2501/50—Cell markers; Cell surface determinants
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    • C12N2501/515—CD3, T-cell receptor complex
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    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

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  • Chemical Kinetics & Catalysis (AREA)
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ES14748807T 2013-02-07 2014-02-06 Procedimientos para la expansión o el empobrecimiento de células T reguladoras Active ES2885423T3 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US201361762136P 2013-02-07 2013-02-07
US201361763217P 2013-02-11 2013-02-11
PCT/US2014/015101 WO2014124134A1 (en) 2013-02-07 2014-02-06 Methods for expansion or depletion of t-regulatory cells

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ES2885423T3 true ES2885423T3 (es) 2021-12-13

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ES14748807T Active ES2885423T3 (es) 2013-02-07 2014-02-06 Procedimientos para la expansión o el empobrecimiento de células T reguladoras

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US (4) US9821010B2 (enExample)
EP (2) EP2953634B1 (enExample)
JP (5) JP6367836B2 (enExample)
DK (1) DK2953634T3 (enExample)
ES (1) ES2885423T3 (enExample)
HR (1) HRP20211353T1 (enExample)
PL (1) PL2953634T3 (enExample)
PT (1) PT2953634T (enExample)
WO (1) WO2014124134A1 (enExample)

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WO2015057968A2 (en) 2013-10-17 2015-04-23 The General Hospital Corporation Methods of identifying subjects responsive to treatment for an autoimmune disease and compositions for treating the same
US10500273B2 (en) * 2015-03-02 2019-12-10 180 Therapeutics Lp Method of treating a localized fibrotic disorder using an IL-33 antagonist
EP4234685A3 (en) 2015-04-17 2023-09-06 Novartis AG Methods for improving the efficacy and expansion of chimeric antigen receptor-expressing cells
FI3447075T3 (fi) 2015-05-15 2023-11-07 Massachusetts Gen Hospital Antagonistisia anti-tuumorinekroositekijäreseptorin superperheen vasta-aineita
CN109476722A (zh) 2015-07-21 2019-03-15 诺华股份有限公司 用于改善免疫细胞的功效和扩张的方法
WO2017040312A1 (en) * 2015-08-28 2017-03-09 The General Hospital Corporation Agonistic anti-tumor necrosis factor receptor 2 antibodies
EP3355914B1 (en) 2015-09-29 2024-03-06 The General Hospital Corporation A composition comprising bcg for reducing cholesterol.
AU2016344745A1 (en) * 2015-10-28 2018-05-17 Life Technologies As Selective expansion of different subpopulations of T cells by the alteration of cell surfacing signals and signal ratio
US10988543B2 (en) 2015-11-11 2021-04-27 Opi Vi—Ip Holdco Llc Humanized anti-tumor necrosis factor alpha receptor 2 (anti-TNFR2) antibodies and methods of use thereof to elicit an immune response against a tumor
CN121294437A (zh) 2015-12-04 2026-01-09 诺华股份有限公司 用于免疫肿瘤学的组合物和方法
TW201726744A (zh) * 2016-01-11 2017-08-01 奧托德里克有限公司 用於檢測奧美沙坦(olmesartan)及改善治療高血壓之遵從性的組成物、裝置及方法
WO2017197331A2 (en) * 2016-05-13 2017-11-16 The General Hospital Corporation Antagonistic anti-tumor necrosis factor receptor superfamily antibodies
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