ES2874077T3 - Métodos y compuestos mejorados para eliminar respuestas inmunitarias a agentes terapéuticos - Google Patents
Métodos y compuestos mejorados para eliminar respuestas inmunitarias a agentes terapéuticos Download PDFInfo
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- ES2874077T3 ES2874077T3 ES16778714T ES16778714T ES2874077T3 ES 2874077 T3 ES2874077 T3 ES 2874077T3 ES 16778714 T ES16778714 T ES 16778714T ES 16778714 T ES16778714 T ES 16778714T ES 2874077 T3 ES2874077 T3 ES 2874077T3
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Classifications
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- C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
- C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
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- A61K39/001—Preparations to induce tolerance to non-self, e.g. prior to transplantation
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- C—CHEMISTRY; METALLURGY
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- A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
- A61K2035/122—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells for inducing tolerance or supression of immune responses
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- A61K2039/57—Medicinal preparations containing antigens or antibodies characterised by the type of response, e.g. Th1, Th2
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- A—HUMAN NECESSITIES
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- A61K2039/62—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier
- A61K2039/627—Medicinal preparations containing antigens or antibodies characterised by the link between antigen and carrier characterised by the linker
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- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
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- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K2319/00—Fusion polypeptide
- C07K2319/40—Fusion polypeptide containing a tag for immunodetection, or an epitope for immunisation
Landscapes
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- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
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- Biomedical Technology (AREA)
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- Transplantation (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Peptides Or Proteins (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
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| EP2247306B1 (en) | 2008-02-14 | 2018-04-18 | Life Sciences Research Partners VZW | Immunogenic control of tumours and tumour cells |
| ES2924027T3 (es) | 2010-11-25 | 2022-10-04 | Imcyse Sa | Péptidos inmunogénicos para su uso en la prevención y/o tratamiento de enfermedades infecciosas, enfermedades autoinmunitarias, respuestas inmunitarias a alofactores, enfermedades alérgicas, tumores, rechazo de injerto y respuestas inmunitarias contra vectores virales usados para terapia génica o vacunación génica |
| GB201201511D0 (en) | 2012-01-30 | 2012-03-14 | Univ Leuven Kath | Modified epitopes for boosting CD4+ T-cell responses |
| GB201309469D0 (en) | 2013-05-28 | 2013-07-10 | Imcyse Sa | Detection of CD4+ T lymphocytes |
| GB201418433D0 (en) | 2014-10-17 | 2014-12-03 | Imcyse Sa | Novel immunogenic peptides |
| US10729791B2 (en) | 2015-05-18 | 2020-08-04 | Imcyse Sa | Animal models for evaluating pharmaceutical compounds |
| JP7090335B2 (ja) | 2015-09-25 | 2022-06-24 | イムサイス エスエー | 治療剤に対する免疫応答を除去するための改善された方法及び化合物 |
| AU2017252192C1 (en) | 2016-04-19 | 2023-06-08 | Imcyse Sa | Novel immunogenic CD1d binding peptides |
| EP3592765A1 (en) | 2017-03-09 | 2020-01-15 | ImCyse SA | Peptides and methods for the treatment of diabetes |
| US20230113747A1 (en) * | 2019-05-16 | 2023-04-13 | Imcyse Sa | Immunogenic peptides with an oxidoreductase motif comprising a modified cysteine |
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| CN115867567A (zh) * | 2020-05-06 | 2023-03-28 | 易姆赛斯股份公司 | 具有新氧化还原酶基序的免疫原性肽 |
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| CN113621030B (zh) * | 2020-07-14 | 2023-05-26 | 上海科技大学 | 一种诱导蛋白质降解的多肽及其应用 |
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| US4599231A (en) | 1984-03-09 | 1986-07-08 | Scripps Clinic And Research Foundation | Synthetic hepatitis B virus vaccine including both T cell and B cell determinants |
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| US4886782A (en) | 1987-02-26 | 1989-12-12 | The United States Of America As Represented By The Department Of Health And Human Services | Malarial immunogen |
| US5433948A (en) | 1990-02-13 | 1995-07-18 | Thomas; Wayne R. | Cloning and sequencing of allergens of dermatophagoides (house dust mite) |
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| ATE444360T1 (de) | 1991-10-16 | 2009-10-15 | Merck Patent Gmbh | T-zell epitopen von den wichtigsten allergene von dermatophagoides (hausmilbe) |
| US7252829B1 (en) | 1998-06-17 | 2007-08-07 | Idm Pharma, Inc. | HLA binding peptides and their uses |
| US5589582A (en) | 1992-10-27 | 1996-12-31 | Biotransplant, Inc. | Polynucleotides en coding porcine cytokines |
| US5633234A (en) | 1993-01-22 | 1997-05-27 | The Johns Hopkins University | Lysosomal targeting of immunogens |
| US5824315A (en) | 1993-10-25 | 1998-10-20 | Anergen, Inc. | Binding affinity of antigenic peptides for MHC molecules |
| US8791237B2 (en) | 1994-11-08 | 2014-07-29 | The Trustees Of The University Of Pennsylvania | Compositions and methods for treatment of non-hodgkins lymphoma |
| US7157089B1 (en) | 1996-11-26 | 2007-01-02 | Stressgen Biotechnologies Corporation | Immune responses using compositions containing stress proteins |
| AU1124499A (en) | 1997-10-28 | 1999-05-17 | Maxygen, Inc. | Human papillomavirus vectors |
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| AR020102A1 (es) | 1998-07-30 | 2002-04-10 | Ucb Sa | Compuesto para la prevencion y/o tratamiento de la alergia; composicion farmaceutica, composicion cosmetica, composicion en forma de bebida, alimento y/oalimento para animales domesticos que lo comprende y uso de dicho compuesto o dicha composicion farmaceutica para la fabricacion de un alimento |
| CA2350911A1 (en) | 1998-11-16 | 2000-05-25 | Board Of Regents, The University Of Texas System | Hiv-specific t-cell induction |
| GB0006437D0 (en) | 2000-03-17 | 2000-05-10 | Leuven Res & Dev Vzw | Compounds for the modulation of allergen sensitivity by antigens sharing T cell epitopes with allergens |
| EP2258835A1 (en) * | 2000-04-28 | 2010-12-08 | Novozymes A/S | Lipolytic enzyme variant |
| AU2001272491A1 (en) | 2000-06-26 | 2002-01-08 | Smithkline Beecham Biologicals (S.A.) | Triple fusion proteins comprising ubiquitin fused between thioredoxin and a polypeptide of interest |
| US7049413B2 (en) | 2001-05-18 | 2006-05-23 | Ludwig Institute For Cancer Research | MAGE-A3 peptides presented by HLA class II molecules |
| EP1409650B1 (en) | 2001-05-30 | 2006-04-12 | Fondazione Telethon | Ex-vivo isolated cd25+cd4+ t cells with immunosuppressive activity and uses thereof |
| JP4537060B2 (ja) | 2001-10-03 | 2010-09-01 | ユニリーバー・ナームローゼ・ベンノートシヤープ | 治療剤および他剤の送達のための炭水化物結合領域含有融合タンパク質、およびそれらを含む組成物 |
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- 2016-09-23 ES ES16778714T patent/ES2874077T3/es active Active
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| HK1252695A1 (en) | 2019-05-31 |
| EP3939606A2 (en) | 2022-01-19 |
| AU2016328582A1 (en) | 2018-03-15 |
| EP3352782B1 (en) | 2021-03-31 |
| US11787849B2 (en) | 2023-10-17 |
| CN108289941B (zh) | 2022-06-21 |
| CA2995771A1 (en) | 2017-03-30 |
| EP3352782A1 (en) | 2018-08-01 |
| AU2016328582B2 (en) | 2022-11-24 |
| EP3939606A3 (en) | 2022-04-20 |
| AU2023201135A1 (en) | 2023-03-30 |
| WO2017050966A1 (en) | 2017-03-30 |
| JP2018528237A (ja) | 2018-09-27 |
| CN108289941A (zh) | 2018-07-17 |
| US20240109951A1 (en) | 2024-04-04 |
| US20180258154A1 (en) | 2018-09-13 |
| JP7090335B2 (ja) | 2022-06-24 |
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