ES2817888T3 - Inhibidor de galactósido de galectina-3 y su uso para tratar fibrosis pulmonar - Google Patents
Inhibidor de galactósido de galectina-3 y su uso para tratar fibrosis pulmonar Download PDFInfo
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- ES2817888T3 ES2817888T3 ES13785446T ES13785446T ES2817888T3 ES 2817888 T3 ES2817888 T3 ES 2817888T3 ES 13785446 T ES13785446 T ES 13785446T ES 13785446 T ES13785446 T ES 13785446T ES 2817888 T3 ES2817888 T3 ES 2817888T3
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- compound
- galectin
- pulmonary fibrosis
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- lung
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- A61K9/0078—Sprays or powders for inhalation; Aerolised or nebulised preparations generated by other means than thermal energy for inhalation via a nebulizer such as a jet nebulizer, ultrasonic nebulizer, e.g. in the form of aqueous drug solutions or dispersions
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Landscapes
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Applications Claiming Priority (5)
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| US201261720641P | 2012-10-31 | 2012-10-31 | |
| CA2794066A CA2794066C (en) | 2012-10-31 | 2012-10-31 | Galactoside inhibitor of galectins |
| CA2795753A CA2795753A1 (en) | 2012-10-31 | 2012-11-15 | Novel galactoside inhibitor of galectins |
| US13/832,672 US9243021B2 (en) | 2012-10-31 | 2013-03-15 | Galactoside inhibitor of galectins |
| PCT/EP2013/072691 WO2014067986A1 (en) | 2012-10-31 | 2013-10-30 | Galactoside inhibitor of galectin-3 and its use for treating pulmonary fibrosis |
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| ES13785446T Active ES2817888T3 (es) | 2012-10-31 | 2013-10-30 | Inhibidor de galactósido de galectina-3 y su uso para tratar fibrosis pulmonar |
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| JP (1) | JP2015535233A (member.php) |
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| ES (1) | ES2817888T3 (member.php) |
| IN (1) | IN2015DN02573A (member.php) |
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| EP2620443A1 (en) | 2012-01-25 | 2013-07-31 | Galecto Biotech AB | Novel galactoside inhibitors of galectins |
| ES2784873T3 (es) | 2014-07-09 | 2020-10-01 | Galecto Biotech Ab | Novedoso inhibidor galactósido híbrido de galectinas |
| ES2776255T3 (es) | 2015-01-16 | 2020-07-29 | Galecto Biotech Ab | Novedoso inhibidor de galactósido de galectinas |
| EP3250581B1 (en) | 2015-01-30 | 2021-01-20 | Galecto Biotech AB | Alpha-d-galactoside inhibitors of galectins |
| CA2983198C (en) | 2015-05-12 | 2022-07-19 | Galecto Biotech Ab | Once-daily treatment of pulmonary fibrosis |
| JP6915956B2 (ja) * | 2015-05-15 | 2021-08-11 | ガレクト・バイオテック・エイビイ | 肺線維症の１日１回の治療 |
| US10799522B2 (en) * | 2015-07-27 | 2020-10-13 | Wayne State University | Compositions and methods relating to galectin detection |
| WO2017080973A1 (en) | 2015-11-09 | 2017-05-18 | Galecto Biotech Ab | 1,1 '-sulfanediyl-di-beta-d-galactopyranosides as inhibitors of galectins |
| CA3004632A1 (en) | 2015-12-18 | 2017-06-22 | Galecto Biotech Ab | Polymorphic forms and process |
| US20190367552A1 (en) * | 2016-03-04 | 2019-12-05 | Galectin Sciences, Llc | Selenogalactoside compounds for the prevention and treatment of diseases associated with galectin and the use thereof |
| US10889610B2 (en) | 2016-07-12 | 2021-01-12 | Galecto Biotech Ab | Alpha-D-galactoside inhibitors of galectins |
| CN109563120B (zh) * | 2016-07-12 | 2022-12-02 | 格莱克特生物技术公司 | 半乳糖凝集素的α-D-半乳糖苷抑制剂 |
| AU2018265571B2 (en) | 2017-05-12 | 2022-09-29 | Galectin Sciences, Llc | Compounds for the prevention and treatment of diseases and the use thereof |
| WO2019067702A1 (en) | 2017-09-27 | 2019-04-04 | Bristol-Myers Squibb Company | INHIBITORS WITH SMALL MOLECULES OF GALECTIN-3 |
| US11072626B2 (en) | 2017-10-11 | 2021-07-27 | Bristol-Myers Squibb Company | Small molecule inhibitors of Galectin-3 |
| CA3085356A1 (en) | 2017-12-29 | 2019-07-04 | Glycomimetics, Inc. | Heterobifunctional inhibitors of e-selectin and galectin-3 |
| WO2019137971A1 (en) | 2018-01-10 | 2019-07-18 | Galecto Biotech Ab | Novel galactoside inhibitor of galectins |
| AU2019271285B2 (en) * | 2018-05-17 | 2024-10-03 | Actuate Therapeutics, Inc. | Treatment of idiopathic pulmonary fibrosis with glycogen synthase kinase 3 form beta inhibitors |
| ES2912499T3 (es) * | 2018-06-15 | 2022-05-26 | Bristol Myers Squibb Co | Miméticos de tiodisacáridos a base de tetrahidropirano como inhibidores de galectina-3 |
| CN112672765A (zh) * | 2018-06-29 | 2021-04-16 | 格莱科斯生物医药公司 | 结合物 |
| JP2022508720A (ja) | 2018-10-15 | 2022-01-19 | ガレクト バイオテック エービー | ガレクチンのガラクトシド阻害剤 |
| WO2020078807A1 (en) | 2018-10-15 | 2020-04-23 | Galecto Biotech Ab | Prodrug of galactoside inhibitors of galectins |
| EP3883946A1 (en) | 2018-11-21 | 2021-09-29 | Galecto Biotech AB | Alpha-d-galactoside inhibitors of galectins |
| KR20210100139A (ko) | 2018-12-06 | 2021-08-13 | 브리스톨-마이어스 스큅 컴퍼니 | 갈렉틴-3의 소분자 억제제 |
| CA3122321A1 (en) | 2018-12-27 | 2020-07-02 | Glycomimetics, Inc. | Galectin-3 inhibiting c-glycosides |
| US11845771B2 (en) | 2018-12-27 | 2023-12-19 | Glycomimetics, Inc. | Heterobifunctional inhibitors of E-selectin and galectin-3 |
| EP3947407B1 (en) | 2019-03-26 | 2024-06-12 | Bristol-Myers Squibb Company | Small molecule inhibitors of galectin-3 |
| US12269819B2 (en) | 2019-04-10 | 2025-04-08 | Bristol-Myers Squibb Company | Small molecule inhibitors of Galectin-3 |
| CA3138668A1 (en) | 2019-06-14 | 2020-12-17 | Denis Giguere | Synthesis of 3-azido-3-deoxy-d-galactopyranose |
| CA3144551A1 (en) | 2019-06-24 | 2020-12-30 | Galecto Biotech Ab | Large scale process of 3,3'-dideoxy-3,3'-bis-[4-(3-fluorophenyl)-1h-1,2,3-triazol-1-yl]-1,1'-sulfanediyl-di-beta-d-galactopyranoside |
| WO2021001538A1 (en) | 2019-07-03 | 2021-01-07 | Galecto Biotech Ab | Novel galactoside inhibitor of galectins |
| CN114555620A (zh) | 2019-07-03 | 2022-05-27 | 格莱克特生物技术公司 | 半乳糖凝集素的新型半乳糖苷抑制剂 |
| US12441755B2 (en) | 2019-07-05 | 2025-10-14 | Galecto Biotech Ab | Galactoside inhibitor of galectins |
| CA3147078A1 (en) | 2019-08-09 | 2021-02-18 | Martin Bolli | (2-acetamidyl)thio-beta-d-galactopyranoside derivatives |
| CN114206893A (zh) | 2019-08-09 | 2022-03-18 | 爱杜西亚药品有限公司 | (杂)芳基-甲基-硫代-β-D-吡喃半乳糖苷衍生物 |
| JP7604457B2 (ja) | 2019-08-15 | 2024-12-23 | イドルシア・ファーマシューティカルズ・リミテッド | ２－ヒドロキシシクロアルカン－１－カルバモイル誘導体 |
| RS65294B1 (sr) | 2019-08-29 | 2024-04-30 | Idorsia Pharmaceuticals Ltd | Derivati alfa-d-galaktopiranozida |
| WO2021123506A1 (en) | 2019-12-18 | 2021-06-24 | Glykos Biomedical Oy | Stabile conjugate |
| WO2021195020A1 (en) * | 2020-03-23 | 2021-09-30 | G3 Pharmaceuticals, Inc. | Methods and compositions for preventing and treating fibrosis resulting from a coronavirus infection |
| JP2023519952A (ja) | 2020-03-31 | 2023-05-15 | ガレクト バイオテック エービー | １，２，４，６－テトラ－ｏ－アセチル－３－アジド－３－デオキシ－ｄ－ガラクトピラノシドを調製するための大規模方法 |
| EP4146646A1 (en) | 2020-05-05 | 2023-03-15 | Bristol-Myers Squibb Company | Small molecule inhibitors of galectin-3 |
| JP7677995B2 (ja) | 2020-05-11 | 2025-05-15 | ブリストル－マイヤーズ スクイブ カンパニー | ガレクチン－３の低分子阻害剤 |
| WO2021242982A1 (en) | 2020-05-28 | 2021-12-02 | Bristol-Myers Squibb Company | Galectin-3 inhibitors |
| IL301815A (en) | 2020-10-06 | 2023-06-01 | Idorsia Pharmaceuticals Ltd | Spiro derivatives of alpha-d-galactopyranosides |
| JP2023547241A (ja) | 2020-11-02 | 2023-11-09 | イドーシア ファーマシューティカルズ リミテッド | ガレクチン－３を阻害する２－ヒドロキシシクロアルカン－１－カルバモイル誘導体 |
| KR20230145111A (ko) | 2021-02-09 | 2023-10-17 | 이도르시아 파마슈티컬스 리미티드 | 히드록시헤테로시클로알칸-카르바모일 유도체 |
| IL305581A (en) | 2021-03-03 | 2023-10-01 | Idorsia Pharmaceuticals Ltd | Triazolyl-methyl-converted alpha-D-galactopyranoside histories |
| WO2025111704A1 (en) * | 2023-12-01 | 2025-06-05 | UNIVERSITé LAVAL | Selective inhibitors of galectin-3 |
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| US5152456A (en) | 1989-12-12 | 1992-10-06 | Bespak, Plc | Dispensing apparatus having a perforate outlet member and a vibrating device |
| GB9027234D0 (en) | 1990-12-15 | 1991-02-06 | Harris Pharma Ltd | An inhalation device |
| EP0940154B1 (en) | 1991-07-02 | 2007-04-18 | Nektar Therapeutics | Device for delivering aerosolized medicaments |
| DE69618624T2 (de) | 1996-01-03 | 2002-08-08 | Glaxo Group Ltd., Greenford | Inhaliervorrichtung |
| DE19726110C2 (de) | 1997-06-20 | 1999-07-22 | Draegerwerk Ag | Aerosolgenerator für Beatmungssysteme |
| US6962151B1 (en) | 1999-11-05 | 2005-11-08 | Pari GmbH Spezialisten für effektive Inhalation | Inhalation nebulizer |
| DE10102846B4 (de) | 2001-01-23 | 2012-04-12 | Pari Pharma Gmbh | Aerosolgenerator |
| ATE269735T1 (de) | 2001-10-18 | 2004-07-15 | Pari Gmbh | Inhalationstherapievorrichtung |
| JP2005513031A (ja) * | 2001-11-26 | 2005-05-12 | アラクノーバ・セラピューティックス・リミテッド | 肺線維症の処置のためのｐｐａｒアクチベーターの使用 |
| EP1386672B1 (en) | 2002-08-02 | 2010-04-07 | PARI Pharma GmbH | Fluid droplet production apparatus |
| DE10250625A1 (de) | 2002-10-30 | 2004-05-19 | Pari GmbH Spezialisten für effektive Inhalation | Inhalationstherapievorrichtung |
| DE10257381B4 (de) | 2002-12-09 | 2006-09-14 | Pari GmbH Spezialisten für effektive Inhalation | Inhalationstherapievorrichtung |
| SE0401301D0 (sv) | 2004-05-21 | 2004-05-21 | Forskarpatent I Syd Ab | Novel 3-triazolyl-galactoside inhibitors of galectins |
| SE0401300D0 (sv) | 2004-05-21 | 2004-05-21 | Forskarpatent I Syd Ab | Novel Galactoside Inhibitors of Galectins |
| JPWO2006009209A1 (ja) * | 2004-07-22 | 2008-05-01 | 科研製薬株式会社 | 慢性炎症性肺疾患を予防もしくは治療する薬剤 |
| US8703720B2 (en) | 2009-04-28 | 2014-04-22 | Galecto Biotech Ab | Galactoside inhibitors of galectins |
| DE102009026636B4 (de) | 2009-06-02 | 2011-04-14 | Pari Pharma Gmbh | Verfahren zum Verschweißen einer Membran mit einem Träger bei der Herstellung eines Membranverneblers |
| CN108014340A (zh) * | 2011-04-12 | 2018-05-11 | 莫伊莱麦屈克斯公司 | 用于预防或治疗以成纤维细胞异常增殖及细胞外基质沉积为特征的疾病的组合物和方法 |
-
2013
- 2013-10-30 IN IN2573DEN2015 patent/IN2015DN02573A/en unknown
- 2013-10-30 CA CA2884802A patent/CA2884802A1/en not_active Abandoned
- 2013-10-30 ES ES13785446T patent/ES2817888T3/es active Active
- 2013-10-30 JP JP2015538502A patent/JP2015535233A/ja active Pending
- 2013-10-30 EP EP17183955.8A patent/EP3278805A1/en not_active Withdrawn
- 2013-10-30 EP EP13785446.9A patent/EP2914269B1/en active Active
- 2013-10-30 WO PCT/EP2013/072691 patent/WO2014067986A1/en not_active Ceased
- 2013-10-30 CN CN201380057194.2A patent/CN104755088A/zh active Pending
Also Published As
| Publication number | Publication date |
|---|---|
| CN104755088A (zh) | 2015-07-01 |
| WO2014067986A8 (en) | 2016-04-14 |
| IN2015DN02573A (member.php) | 2015-09-11 |
| EP3278805A1 (en) | 2018-02-07 |
| WO2014067986A1 (en) | 2014-05-08 |
| EP2914269B1 (en) | 2020-07-29 |
| EP2914269A1 (en) | 2015-09-09 |
| JP2015535233A (ja) | 2015-12-10 |
| CA2884802A1 (en) | 2014-05-08 |
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