ES2753216T3 - Formulación de anticuerpos anti-IL17RA y regímenes terapéuticos para el tratamiento de la psoriasis - Google Patents

Formulación de anticuerpos anti-IL17RA y regímenes terapéuticos para el tratamiento de la psoriasis Download PDF

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Publication number
ES2753216T3
ES2753216T3 ES17195530T ES17195530T ES2753216T3 ES 2753216 T3 ES2753216 T3 ES 2753216T3 ES 17195530 T ES17195530 T ES 17195530T ES 17195530 T ES17195530 T ES 17195530T ES 2753216 T3 ES2753216 T3 ES 2753216T3
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Spain
Prior art keywords
administered
dose
psoriasis
week
administration
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English (en)
Spanish (es)
Inventor
Dingjiang Liu
Holly Zhuohong Huang
David Andrew Martin
Christopher Boyd Russell
David H Salinger
Scott Walter Baumgartner
Christopher J Endres
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Amgen K A Inc
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Amgen K A Inc
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/08Solutions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2866Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against receptors for cytokines, lymphokines, interferons
    • AHUMAN NECESSITIES
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    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
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    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • AHUMAN NECESSITIES
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    • A61K39/395Antibodies; Immunoglobulins; Immune serum, e.g. antilymphocytic serum
    • A61K39/39591Stabilisation, fragmentation
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    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/16Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing nitrogen, e.g. nitro-, nitroso-, azo-compounds, nitriles, cyanates
    • A61K47/18Amines; Amides; Ureas; Quaternary ammonium compounds; Amino acids; Oligopeptides having up to five amino acids
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    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00Medicinal preparations characterised by special physical form
    • A61K9/0012Galenical forms characterised by the site of application
    • A61K9/0019Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021Intradermal administration, e.g. through microneedle arrays, needleless injectors
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    • A61P1/16Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
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    • AHUMAN NECESSITIES
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    • A61P37/00Drugs for immunological or allergic disorders
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
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    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
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    • AHUMAN NECESSITIES
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    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/02Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
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    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00Drugs for disorders of the blood or the extracellular fluid
    • A61P7/06Antianaemics
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/505Medicinal preparations containing antigens or antibodies comprising antibodies
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/54Medicinal preparations containing antigens or antibodies characterised by the route of administration
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00Medicinal preparations containing antigens or antibodies
    • A61K2039/545Medicinal preparations containing antigens or antibodies characterised by the dose, timing or administration schedule
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/50Immunoglobulins specific features characterized by immunoglobulin fragments
    • C07K2317/56Immunoglobulins specific features characterized by immunoglobulin fragments variable (Fv) region, i.e. VH and/or VL
    • C07K2317/565Complementarity determining region [CDR]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/70Immunoglobulins specific features characterized by effect upon binding to a cell or to an antigen
    • C07K2317/76Antagonist effect on antigen, e.g. neutralization or inhibition of binding

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  • Health & Medical Sciences (AREA)
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  • General Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Immunology (AREA)
  • Epidemiology (AREA)
  • Diabetes (AREA)
  • Dermatology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Mycology (AREA)
  • Microbiology (AREA)
  • Hematology (AREA)
  • Physical Education & Sports Medicine (AREA)
  • Pulmonology (AREA)
  • Endocrinology (AREA)
  • Neurology (AREA)
  • Orthopedic Medicine & Surgery (AREA)
  • Rheumatology (AREA)
  • Oncology (AREA)
  • Emergency Medicine (AREA)
  • Reproductive Health (AREA)
  • Pain & Pain Management (AREA)
  • Neurosurgery (AREA)
  • Communicable Diseases (AREA)
  • Obesity (AREA)
ES17195530T 2010-01-15 2011-01-12 Formulación de anticuerpos anti-IL17RA y regímenes terapéuticos para el tratamiento de la psoriasis Active ES2753216T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US29538710P 2010-01-15 2010-01-15
US42205910P 2010-12-10 2010-12-10

Publications (1)

Publication Number Publication Date
ES2753216T3 true ES2753216T3 (es) 2020-04-07

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ID=43858045

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Application Number Title Priority Date Filing Date
ES17195530T Active ES2753216T3 (es) 2010-01-15 2011-01-12 Formulación de anticuerpos anti-IL17RA y regímenes terapéuticos para el tratamiento de la psoriasis
ES11705713.3T Active ES2652637T3 (es) 2010-01-15 2011-01-12 Formulación de anticuerpos y regímenes terapéuticos

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES11705713.3T Active ES2652637T3 (es) 2010-01-15 2011-01-12 Formulación de anticuerpos y regímenes terapéuticos

Country Status (38)

Country Link
US (5) US8883151B2 (forum.php)
EP (3) EP3632466A1 (forum.php)
JP (2) JP5743234B2 (forum.php)
KR (1) KR101766936B1 (forum.php)
CN (1) CN102821787B (forum.php)
AR (1) AR079903A1 (forum.php)
AU (3) AU2011205402B2 (forum.php)
BR (1) BR112012017150B1 (forum.php)
CA (1) CA2787128C (forum.php)
CL (1) CL2012001966A1 (forum.php)
CO (1) CO6640206A2 (forum.php)
CR (1) CR20120419A (forum.php)
CY (2) CY1119852T1 (forum.php)
DK (2) DK2523688T3 (forum.php)
EA (2) EA201891433A3 (forum.php)
ES (2) ES2753216T3 (forum.php)
HR (1) HRP20171939T1 (forum.php)
HU (2) HUE035618T2 (forum.php)
IL (1) IL220602B (forum.php)
IN (1) IN2012DN06720A (forum.php)
LT (2) LT3295957T (forum.php)
MA (1) MA33989B1 (forum.php)
MX (1) MX349856B (forum.php)
MY (1) MY182680A (forum.php)
NO (1) NO2523688T3 (forum.php)
NZ (1) NZ601125A (forum.php)
PE (1) PE20121691A1 (forum.php)
PH (1) PH12012501364A1 (forum.php)
PL (2) PL2523688T3 (forum.php)
PT (2) PT2523688T (forum.php)
RS (2) RS59743B1 (forum.php)
SG (2) SG10201604093XA (forum.php)
SI (2) SI2523688T1 (forum.php)
TN (1) TN2012000335A1 (forum.php)
TW (1) TWI554282B (forum.php)
UA (1) UA112288C2 (forum.php)
WO (1) WO2011088120A1 (forum.php)
ZA (1) ZA201205167B (forum.php)

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JP6795397B2 (ja) * 2014-09-10 2020-12-02 日油株式会社 蛋白質吸着抑制剤及び蛋白質吸着抑制方法
KR102745501B1 (ko) 2014-12-03 2024-12-23 체에스엘 베링 아게 면역글로불린을 포함하는 안정성이 증가된 약제학적 제품
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JP6909208B2 (ja) 2015-09-17 2021-07-28 アムジェン インコーポレイテッド Il23経路バイオマーカーを使用するil23アンタゴニストに対する臨床応答の予測
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JP6694522B2 (ja) 2016-04-19 2020-05-13 セイジ・エレクトロクロミクス,インコーポレイテッド 透明導電性酸化物層及びバスバーを含むエレクトロクロミックデバイス、ならびにその形成プロセス
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