ES2721174T3 - Modalidades mejoradas para el tratamiento de enfermedades degenerativas de la retina - Google Patents

Modalidades mejoradas para el tratamiento de enfermedades degenerativas de la retina Download PDF

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Publication number
ES2721174T3
ES2721174T3 ES11183613T ES11183613T ES2721174T3 ES 2721174 T3 ES2721174 T3 ES 2721174T3 ES 11183613 T ES11183613 T ES 11183613T ES 11183613 T ES11183613 T ES 11183613T ES 2721174 T3 ES2721174 T3 ES 2721174T3
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Prior art keywords
retina
treatment
degenerative diseases
rpe cells
human embryonic
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Expired - Lifetime
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ES11183613T
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English (en)
Spanish (es)
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Irina Klimanskaya
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Astellas Institute for Regenerative Medicine
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Astellas Institute for Regenerative Medicine
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    • A—HUMAN NECESSITIES
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/30—Nerves; Brain; Eyes; Corneal cells; Cerebrospinal fluid; Neuronal stem cells; Neuronal precursor cells; Glial cells; Oligodendrocytes; Schwann cells; Astroglia; Astrocytes; Choroid plexus; Spinal cord tissue
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
    • A61K35/44—Vessels; Vascular smooth muscle cells; Endothelial cells; Endothelial progenitor cells
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
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    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P27/00—Drugs for disorders of the senses
    • A61P27/02—Ophthalmic agents
    • A—HUMAN NECESSITIES
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/062—Sensory transducers, e.g. photoreceptors; Sensory neurons, e.g. for hearing, taste, smell, pH, touch, temperature, pain
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    • C12N5/00—Undifferentiated human, animal or plant cells, e.g. cell lines; Tissues; Cultivation or maintenance thereof; Culture media therefor
    • C12N5/06—Animal cells or tissues; Human cells or tissues
    • C12N5/0602—Vertebrate cells
    • C12N5/0618—Cells of the nervous system
    • C12N5/0621—Eye cells, e.g. cornea, iris pigmented cells
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    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K35/00—Medicinal preparations containing materials or reaction products thereof with undetermined constitution
    • A61K35/12—Materials from mammals; Compositions comprising non-specified tissues or cells; Compositions comprising non-embryonic stem cells; Genetically modified cells
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/01—Modulators of cAMP or cGMP, e.g. non-hydrolysable analogs, phosphodiesterase inhibitors, cholera toxin
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/115—Basic fibroblast growth factor (bFGF, FGF-2)
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/15—Transforming growth factor beta (TGF-β)
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/10—Growth factors
    • C12N2501/155—Bone morphogenic proteins [BMP]; Osteogenins; Osteogenic factor; Bone inducing factor
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    • C12N2501/00—Active agents used in cell culture processes, e.g. differentation
    • C12N2501/30—Hormones
    • C12N2501/33—Insulin
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    • C12N2506/00—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells
    • C12N2506/02—Differentiation of animal cells from one lineage to another; Differentiation of pluripotent cells from embryonic cells

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  • Bioinformatics & Cheminformatics (AREA)
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  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Neurosurgery (AREA)
  • Wood Science & Technology (AREA)
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  • Developmental Biology & Embryology (AREA)
  • Ophthalmology & Optometry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
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  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
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  • Acoustics & Sound (AREA)
  • Physics & Mathematics (AREA)
  • Urology & Nephrology (AREA)
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ES11183613T 2004-01-23 2005-01-24 Modalidades mejoradas para el tratamiento de enfermedades degenerativas de la retina Expired - Lifetime ES2721174T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US53896404P 2004-01-23 2004-01-23

Publications (1)

Publication Number Publication Date
ES2721174T3 true ES2721174T3 (es) 2019-07-29

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ES11183613T Expired - Lifetime ES2721174T3 (es) 2004-01-23 2005-01-24 Modalidades mejoradas para el tratamiento de enfermedades degenerativas de la retina

Country Status (15)

Country Link
US (6) US7736896B2 (https=)
EP (8) EP2929782A1 (https=)
JP (10) JP2007522131A (https=)
KR (3) KR101398356B1 (https=)
CN (3) CN1968608B (https=)
AU (6) AU2005207042B2 (https=)
BR (1) BRPI0507074A (https=)
CA (2) CA2555370C (https=)
ES (1) ES2721174T3 (https=)
HK (2) HK1216068A1 (https=)
IL (3) IL177015B (https=)
MX (4) MX375065B (https=)
NZ (1) NZ548929A (https=)
SG (4) SG188122A1 (https=)
WO (1) WO2005070011A2 (https=)

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