ES2718474T3 - Receptores murinos de células T anti-NY-ESO-1 - Google Patents

Receptores murinos de células T anti-NY-ESO-1 Download PDF

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Publication number
ES2718474T3
ES2718474T3 ES13726389T ES13726389T ES2718474T3 ES 2718474 T3 ES2718474 T3 ES 2718474T3 ES 13726389 T ES13726389 T ES 13726389T ES 13726389 T ES13726389 T ES 13726389T ES 2718474 T3 ES2718474 T3 ES 2718474T3
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seq
amino acid
acid sequence
tcr
chain
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ES13726389T
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English (en)
Spanish (es)
Inventor
Maria R Parkhurst
Richard A Morgan
Steven A Rosenberg
Shannon Faith Rosati
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US Department of Health and Human Services
Office of Technology Transfer
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US Department of Health and Human Services
Office of Technology Transfer
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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503Immunoglobulin superfamily
    • C07K14/7051T-cell receptor (TcR)-CD3 complex
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2803Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily
    • C07K16/2809Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the immunoglobulin superfamily against the T-cell receptor (TcR)-CD3 complex
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/30Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants from tumour cells
    • C07K16/3069Reproductive system, e.g. ovaria, uterus, testes, prostate
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/06Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K7/00Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04Linear peptides containing only normal peptide links
    • C07K7/08Linear peptides containing only normal peptide links having 12 to 20 amino acids
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/574Immunoassay; Biospecific binding assay; Materials therefor for cancer
    • G01N33/57484Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites
    • G01N33/57492Immunoassay; Biospecific binding assay; Materials therefor for cancer involving compounds serving as markers for tumor, cancer, neoplasia, e.g. cellular determinants, receptors, heat shock/stress proteins, A-protein, oligosaccharides, metabolites involving compounds localized on the membrane of tumor or cancer cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/68Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing involving proteins, peptides or amino acids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2317/00Immunoglobulins specific features
    • C07K2317/20Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/21Immunoglobulins specific features characterized by taxonomic origin from primates, e.g. man
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K2319/00Fusion polypeptide
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2510/00Genetically modified cells
    • GPHYSICS
    • G01MEASURING; TESTING
    • G01NINVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N2333/00Assays involving biological materials from specific organisms or of a specific nature
    • G01N2333/435Assays involving biological materials from specific organisms or of a specific nature from animals; from humans
    • G01N2333/705Assays involving receptors, cell surface antigens or cell surface determinants
    • G01N2333/70503Immunoglobulin superfamily, e.g. VCAMs, PECAM, LFA-3
    • G01N2333/7051T-cell receptor (TcR)-CD3 complex

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  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Immunology (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Engineering & Computer Science (AREA)
  • Hematology (AREA)
  • Urology & Nephrology (AREA)
  • Biomedical Technology (AREA)
  • Oncology (AREA)
  • Food Science & Technology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Toxicology (AREA)
  • Hospice & Palliative Care (AREA)
  • Gynecology & Obstetrics (AREA)
  • Pregnancy & Childbirth (AREA)
  • Reproductive Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
ES13726389T 2012-05-22 2013-05-22 Receptores murinos de células T anti-NY-ESO-1 Active ES2718474T3 (es)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US201261650020P 2012-05-22 2012-05-22
PCT/US2013/042162 WO2013177247A1 (en) 2012-05-22 2013-05-22 Murine anti-ny-eso-1 t cell receptors

Publications (1)

Publication Number Publication Date
ES2718474T3 true ES2718474T3 (es) 2019-07-02

Family

ID=48539439

Family Applications (3)

Application Number Title Priority Date Filing Date
ES19152955T Active ES2835200T3 (es) 2012-05-22 2013-05-22 Uso médico de células que comprenden receptores de células T anti-NY-ESO-1
ES13726389T Active ES2718474T3 (es) 2012-05-22 2013-05-22 Receptores murinos de células T anti-NY-ESO-1
ES20201340T Active ES2998514T3 (en) 2012-05-22 2013-05-22 Pharmaceutical composition comprising host cells encoding anti-ny-eso-1 t cell receptors

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES19152955T Active ES2835200T3 (es) 2012-05-22 2013-05-22 Uso médico de células que comprenden receptores de células T anti-NY-ESO-1

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES20201340T Active ES2998514T3 (en) 2012-05-22 2013-05-22 Pharmaceutical composition comprising host cells encoding anti-ny-eso-1 t cell receptors

Country Status (10)

Country Link
US (3) US9487573B2 (OSRAM)
EP (3) EP2852613B1 (OSRAM)
JP (2) JP6378172B2 (OSRAM)
CN (2) CN107881183B (OSRAM)
AU (1) AU2013266421B2 (OSRAM)
CA (1) CA2874486C (OSRAM)
ES (3) ES2835200T3 (OSRAM)
IL (1) IL235720A0 (OSRAM)
PT (2) PT2852613T (OSRAM)
WO (1) WO2013177247A1 (OSRAM)

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EP3067366A1 (en) * 2015-03-13 2016-09-14 Max-Delbrück-Centrum Für Molekulare Medizin Combined T cell receptor gene therapy of cancer against MHC I and MHC II-restricted epitopes of the tumor antigen NY-ESO-1
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Also Published As

Publication number Publication date
PT3527584T (pt) 2021-01-04
CN104507963A (zh) 2015-04-08
CN107881183B (zh) 2021-04-02
US20170029483A1 (en) 2017-02-02
US20150141347A1 (en) 2015-05-21
IL235720A0 (en) 2015-01-29
EP3527584A1 (en) 2019-08-21
CN107881183A (zh) 2018-04-06
US10407485B2 (en) 2019-09-10
CN104507963B (zh) 2017-12-15
US20180371050A1 (en) 2018-12-27
ES2998514T3 (en) 2025-02-20
ES2835200T3 (es) 2021-06-22
AU2013266421B2 (en) 2017-06-01
EP2852613A1 (en) 2015-04-01
AU2013266421A1 (en) 2014-12-04
JP2015525208A (ja) 2015-09-03
EP3828197B1 (en) 2024-10-02
EP3527584B1 (en) 2020-10-14
EP2852613B1 (en) 2019-01-23
HK1251874A1 (zh) 2019-04-26
US9487573B2 (en) 2016-11-08
CA2874486C (en) 2021-08-24
CA2874486A1 (en) 2013-11-28
EP3527584B8 (en) 2020-12-16
WO2013177247A1 (en) 2013-11-28
PT2852613T (pt) 2019-05-20
EP3828197A1 (en) 2021-06-02
US10087230B2 (en) 2018-10-02
JP2018196384A (ja) 2018-12-13
JP6378172B2 (ja) 2018-08-22

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